Publications

TitleAbstractYear
Filter
PMID
Filter
postnatal development of resistance against infection in an experimental model.the postnatal development of resistance against infection was monitored by the treatment of juvenile mice with a virulent strain of listeria monocytogenes. it could be shown that until day 10 after birth, young mice succumbed to an infection with even minimal doses of bacteria. between day 15 and 30, the resistance against infection gradually increases until the rather constant level of grown-up animals is reached (fig. 1). juvenile mice that survive the primary infection are able to build up a ...1978107682
[comparison of two methods of antibiotic sensitivity test: gel diffusion and automatic method using abac apparatus. ii. study on 399 strains isolated in hospital (author's transl)].the authors compared for routine use, the results obtained on 399 strains of gram negative bacilli by two technics of antibiotic sensitivity: the technic of gel diffusion with imprenated discs and an automatic method (abac apparatus). among the antibiotics used as a routine in our laboratory by the diffusion method and the 16 studied with the abac apparatus, 11 are common to both methods and were compared. the concordance of the results was greater than 90% for colistine (94.5%), oxolinic acid ( ...1978107836
conversion of 2,4,6-trinitrophenol to a mutagen by pseudomonas aeruginosa.a strain of pseudomonas aeruginosa reduced 2,4,6-trinitrophenol (picric acid) to 2-amino-4,6-dinitrophenol (picramic acid) under anaerobic conditions. mutagenic assays of picric acid and picramic acid were carried out with histidine-requiring strains of salmonella typhimurium. picric acid (10 micrograms per plate) demonstrated mutagenicity (both frame shift and base substitution-gype mutations) only after activation with a rat liver homogenate preparation. picramic acid (1 microgram per plate) i ...1979107854
isolation and characterization of bacterial flagellar hook proteins from salmonellae and escherichia coli.flagellar hook proteins from salmonella and escherichia coli were dissociated in acid and purified by diethylamino-ethyl-cellulose column chromatography. these two proteins had the same electrophoretic mobility in sodium dodecyl sulfate-polyacrylamide gels. however, analytical electrofocusing patterns showed that these proteins had different isoelectric points (4.7 for salmonella typhimurium and 4.4 for e. coli). immunodiffusion and immuno-electron microscopy carried out with antisera prepared a ...1979108251
a simplified procedure for measuring the class of anti-bacterial antibodies by mixed reverse passive antiglobulin haemagglutination (mrpah).a modified procedure is described for performing the mrpah (mixed reverse passive antiglobulin haemagglutination) reaction as a simple micro-method to measure the classes of bacterial antibodies. this 'bacterial dilution procedure' gave results closely correlated with those obtained by the 'serum (sample) dilution procedure' previously reported and with great economy of materials, labour and time. the method was used to investigate human serum antibodies to br. abortus and s. enteritidis and ser ...1979108336
cost-effective clinical microbiology. 1979109000
effect of listeria monocytogenes lipids on the course of infections with some gram-negative bacilli in mice.the effect of listeria monocytogenes lipids on the course of infections with salmonella enteritidis, yersinia pseudotuberculosis, pseudomonas aeruginosa and klebsiella pneumoniae was studied in mice. the lipids were extracted with chloroform and methanol and used in various doses before and after infection with the bacilli. the lipids significantly increased mouse resistance toward the examined bacteria. the protective effect depended, to a large extent on the applied dose of lipids and its timi ...1979109064
ozonation of mutagenic and carcinogenic polyaromatic amines and polyaromatic hydrocarbons in water.the salmonella-microsome assay for mutagenesis was used to determine the effect of ozone on the mutagenesis of selected carcinogens and mutagens in water. short periods of ozonation were shown to completely inactivate the mutagenicity of several polyaromatic amine mutagens including acriflavine, proflavine, and beta-naphthylamine. selected polyaromatic hydrocarbons were also sensitive to ozonation. kinetic studies revealed that the mutagenicity of benzo(a)pyrene, 3-methylcholanthrene, and 7,12-d ...1979109190
comparative mutagenicity of palmotoxin bo and aflatoxins b1 and m1.the mutagenicity of palmotoxin bo and of aflatoxin m1 relative to that of aflatoxin b1, the potent mutagen, was studied in five ames' tester strains of salmonella typhimurium (ta-98, ta-100, ta-1535, ta-1537, ta-1538). aflatoxins b1 and m1 are both highly mutagenic in a microsome-mediated system in ta-100. the prediction of the relative carcinogenicity of aflatoxin m1 to aflatoxin b1 posed by the mutation of ta-100 is probably more authentic than ta-87. the mutagenic potency of palmotoxin bo is ...1979109559
the emergence of antimicrobial resistance in new zealand. 1979109800
positive control of lac operon expression in vitro by guanosine 5'-diphosphate 3'-diphosphate.maximal expression of the escherichia coli lactose operon in a coupled in vitro transcription-translation system from a salmonella typhimurium rela mutant was strongly dependent upon addition of guanosine 5'-diphosphate 3'-diphosphate (ppgpp). without added ppgpp, at saturating 3',5'-cyclic amp (camp) concentrations, synthesis of beta-galactosidase (beta-d-galactoside galactohydrolase, ec 3.2.1.23) was reproducibly only 5-7% of that which can be obtained with 0.5-0.8 mm ppgpp. experiments in whi ...1979109832
a genetic approach to analysis of transposons.integration of the tetracycline resistance transposon tn10 into laci of a laci-lacz gene fusion permits the isolation of deletions that excise dna from one end of tn10 and fuse tn10 genes with lacz in such a manner that chimeric proteins with beta-galactosidase activity are produced. the synthesis of the chimeric proteins is under the same control as the transposon genes. thus, regulation of expression of tn10 genes can be investigated by measuring beta-galactosidase activity. analysis of tn10-l ...1979109839
iron requirement and chelator production of staphylococci, streptococcus faecalis and enterobacteriaceae.the effect of iron deprivation on growth of 101 aerobic strains of gram-positive and gram-negative bacteria was studied on agar media in the presence of various concentrations of the synthetic iron chelator ethylene diamine diorthohydroxyphenyl acetic acid (edda) and the iron binding protein transferrin. growth of staphylococcus epidermidis was inhibited by 15 mm edda and 1.5 mm transferrin. staphylococcus aureus was only inhibited by 44 mm edda and not by transferrin. none of the strains of s. ...1978110252
effect of salmonella enteritidis 11rx infection on two-stage skin carcinogenesis in mice.s. enteritidis 11rx infection inhibits the growth of a number of transplantable tumours in mice. in addition, oral infection of mice with s. enteritidis 11rx inhibits colon carcinogenesis by 1,2 dimethylhydrazine. this study has examined the effect of s. enteritidis 11rx infection on two-stage skin carcinogenesis in mice using 7,12 dimethylbenz(a)anthracene (dmba) as initiator and croton oil as promoter. no protection was observed in either laca or (balb/c x c57bl/6j)f1 mice when live 11rx was r ...1978110298
aminopeptidase i activities in several microorganisms.aminopeptidase i activity which was found to be localized in the same subcellular fraction and to be similarly heat stable was partially purified by a common procedure from escherichia coli b, escherichia coli k12, enterobacter aerogenes, salmonella typhimurium, serratia marcescens pseudomonas aeruginosa, and proteus vulgaris. the enzyme preparations were shown to contain a single animopeptidase active toward both leucylleucine and methionylalanylserine by mixed-substrate initial-velocity kineti ...1978110425
the association of bacterial mutagenicity of hydrocarbon-derived 'bay-region' dihydrodiols with the iball indices for carcinogenicity and with the extents of dna-binding on mouse skin of the parent hydrocarbons.the mutagenic activities of benz[alpha]anthracene, 7-methylbenz[alpha]anthracene, 7,12-dimethylbenz[alpha]anthracene, 3-methylcholanthrene and benzo[alpha]pyrene, together with those of the trans-dihydrodiols derived from these hydrocarbons that would be expected to yield 'bay-region' vicinal diolepoxides on further metabolism have been examined in assays with s. typhimurium ta100 using post-mitochondrial supernatant fractions prepared from the livers of 3-methylcholanthrene-treated rats. mutage ...1979110477
susceptibility of cba/n mice to infection with salmonella typhimurium: influence of the x-linked gene controlling b lymphocyte function. 1979110879
[paratyphoid c fever. 1 case]. 1979111219
infectious diarrhea. 1979111270
drug therapy reviews: pharmacotherapy of diarrhea.gastrointestinal physiology, and the pathophysiology, diagnosis, symptoms and treatment of acute and chronic diarrhea are reviewed. drugs used in the treatment of diarrhea include opiates (morphine, codeine), synthetic anti-diarrheals (diphenoxylate, loperamide), anticholinergics (atropine, propantheline), adsorbents (kaolin, pectin, cholestyramine resin) and lactobacillus acidophilus. chronic diarrhea and acute diarrhea caused by microorgansims, drugs and viruses are described. the management o ...1979111547
[a case of paratyphoid a occurring in the city of messina]. 1978111633
streptococcus faecalis, a bacterial isolate which protects young chickens from enteric invasion by salmonellae. 1978111659
central thermosensitivity during fever produced by intra-po/ah and intravenous injections of pyrogen.squirrel monkeys with thermodes implanted in the preoptic/anterior hypothalamic (po/ah) region and the medulla oblongata were used to examine three questions about central thermoresponsiveness in fever: does thermoresponsiveness of the po/ah region and medulla change during fevers caused by injection of bacterial endotoxin iv or directly into the po/ah region? does thermosensitivity of these brain regions determine the upper fever limit? is thermoresponsiveness of the po/ah region affected by lo ...1979111777
a lipopolysaccharide-binding cell-surface protein from salmonella minnesota. isolation, partial characterization and occurrence in different enterobacteriaceae.1. protein extracts obtained from salmonella minnesota re mutant cells by treatment with edta/nac1 solution contain a protein which exhibits high affinity to bacterial lipopolysaccharides. the isolation and partial characterization of this lipopolysaccharide-binding protein is described. 2. the protein was purified from edta extracts by a two-step procedure consisting of ion-exchange chromatography on cm-sephadex and preparative polyacrylamide gel electrophoresis at ph 9.5. the yield of the tota ...1979111933
delayed-type hypersensitivity and acquired cellular resistance in mice immunized with killed listeria monocytogenes and adjuvants.delayed-type hypersensitivity (dh) and acquired cellular resistance (arc) to listeria monocytogenes in mice was studied following immunization with killed bacteria in combination with freund's complete adjuvant or the adjuvant dimethyldioctadecylammonium bromide (dda). intracutaneous or intraperitoneal injections of killed listeria mixed with freund's complete adjuvant did neither result in dh nor in acr. intracutaneous injections of killed listeria and dda resulted in an antigen-dose dependent ...1979112043
suppressive effect of bacterial endotoxin on the expression of cell-mediated anti-listeria immunity.intravenous injection of bacterial endotoxin into mice at any time during ongoing infection with listeria monocytogenes resulted in a markedly increased multiplication of this organism in the liver and spleen. experiments designed to investigate the basis of this infection-enhancing effect revealed that endotoxin was also capable of inhibiting the expression of adoptive t-cell-mediated anti-listeria immunity if given to normal recipient mice up to 48 h before they were infused with protective t- ...1979112056
very low frequency and small intensity electromagnetic and magnetic fields as an oecological factor.the effect on microorganisms of electromagnetic and magnetic fields (emf, mf), the frequency and intensity of which were similar to natural ones, was studied. they were found to influence the physiology of bacteria. changes in the rate of proliferation of microbes, in their susceptibility to antibiotic the frequency of formation of recombinants and partial diploids during conjugation of colibacterium were observed during cultivation in these fields.1978112178
the mutagenicity of trimethylphosphate. 1979112474
permeability of the outer membrane of bacteria. 1979112885
salmonella in wildlife from trinidad and grenada, w.i.forty-four of 219 animals from trinidad and grenada, w.i., yielded 20 serotypes of salmonella, 16 of which are known to have been associated with human infection in the united states in recent years. toads (bufo marinus) provided the greatest number of isolates. other carriers were mammals, vultures, lizards, a tree-frog and a cave cockroach.1979113561
[structure and formation of bacterial flagella (author's transl)]. 1979113602
[salmonella paratyphi b osteomyelitis. recurrence after 27 years]. 1979113922
studies on a receptor for pyocin in a r mutant of salmonella minnesota.lipopolysaccharide (lps) isolated from the pyocin sensitive r form strain of salmonella minnesota f6 (chemotype rd1) inhibited the activity of bacteriophage tail-like pyocin p1 whereas no inhibition occurred with lps prepared from the pyocin resistant s form of s. minnesota. subunits of lipopolysaccharide obtained by treatment with sodium deoxycholate and the polysaccharide fraction of the lipopolysaccharide obtained by acid hydrolysis were shown to be still active whereas lipid a fraction had n ...1979113953
[current zoonoses from the food hygiene point of view (author's transl)].of the numerous zoonoses part of which are reportable, according to the federal communicable diseases act, the food hygienist attributes topicality at present to salmonellosis, brucellosis, toxoplasmosis, taeniasis (t. saginata), trichinellosis, and sarcosporidiosis. in salmonellosis, combating is directed to breeding and keeping of salmonella-free flocks, poultry offering favourable conditions for this purpose. moreover, one tries to decontaminate feeds through certain pelleting machines with t ...1979113956
redox potential-dependent nitrite metabolism by salmonella typhimurium.salmonellae are generally resistant to the inhibitory effects of nano2. removal of the lipopolysaccharide of salmonella typhimurium by ethylenediaminetetraacetic acid pretreatment did not result in subsequent inhibtion of growth by nano2, indicating that lipopolysaccharide does not function to exclude nano2 from the cell. nano2 disappeared from the medium while the cells were growing, but, after stationary phase was reached, no further losses were observed unless the ph was maintained above 7.0. ...1979114115
conversion of environmental pollutant to mutagens by visible light. 1979114180
action of bacterial endotoxin and lipid a on mitochondrial enzyme activities of cells in culture and subcellular fractions.escherichia coli o127:b8 lipopolysaccharide (lps), prepared by the westphal procedure, caused a marked decrease in the activities of mitochondrial malate dehydrogenase, succinate dehydrogenase, and adenylate kinase in african green monkey kidney (vero) cells and primary cultures of mouse liver cells within 2 h after exposure to 10 micrograms of lps/ml of culture medium. these three enzyme activities leaked into the supernatant fraction, and cytochrome oxidase activity was lost from the mouse liv ...1979114491
allotypic and idiotypic specificities of rabbit antibodies showing simple spectrotype. 1979114749
studies on egg disinfection.various concentrations of alkyldimethylbenzyl ammonium chloride (qac), na2co3, and ethylenediaminetetracetic acid (edta) were tested for antimicrobial activity singly and in combination against escherichia coli, arizona hinshawii, and pseudomonas aeruginosa. bactericidal activity of the reagents were evaluated in embryonating eggs, trypticase soy broth, and a medium containing lecithin. toxicity of the chemicals was assayed in embryonating eggs. an appraisal was made of an egg-washing solution c ...1979114994
enhancement of endotoxic shock by n-acetylmuramyl-l-alanyl-(l-seryl)-d-isoglutamine (muramyl dipeptide).we described elsewhere that the synergistic antitumor activity of endotoxic extracts from re mutants of gram-negative bacteria and trehalose mycolate against guinea pig syngeneic line 10 tumor was abrogated after peptide substances accompanying these extracts had been removed. this activity could be restored by combining peptide-free endotoxin either with cell wall skeleton from bacillus calmette-guérin, a polymeric mycolic acid-arabinogalactan-mucopeptide complex, or with a combination of two s ...1979115579
[prevention of salmonellosis]. 1979115666
immune response after vaginal application of antigens in the rhesus monkey.the immune response after vaginal application of antigens was investigated in six sexually mature female rhesus monkeys. two model antigens, i.e., lipopolysaccharide (lps) of salmonella typhosa and abortive type t-4 coliphages were applied with or without adjuvant. a plastic sponge used as the antigen carrier was introduced into the upper vagina and placed against the ectocervix. for primary immunization, each monkey received 18 vaginal antigen applications and 10 applications for each booster ...1979115725
differences in the genetic control of primary and secondary antibody responses.primary and secondary antibody responses to f and s antigens of salmonella typhimurium have been studied in h and l lines of mice genetically selected for primary reponse to sheep erythrocytes (se) (selection i). the range of interline separation obtained (non-specific effect of selection i) was as large as for the selection antigen in the primary response to f antigen and slightly smaller in the primary response to s antigen. for these two antigens the interline difference was reduced after boo ...1979115781
influence of a sub-therapeutic level of virginiamycin in feed on the incidence and persistence of salmonella typhimurium in experimentally infected swine. 1979115823
sterilization by means of hydrogen chloride: influence of process parameters on biocidal activity. 1979115827
urinary metabolites of 3a,4,5,6,7,7a-hexahydro-3-(1-methyl-5-nitro-1h-imidazol-2-yl)-1,2-benzisoxazole in the dog.the antiprotozoal drug 3a,4,5,6,7,7a-hexahydro-3-(1-methyl-5-nitro-1h-imidazol-2-yl)-1,2-benzisoxazole (i), which exhibits activity against trypanosomiasis, is also antibacterial in vivo. since the urine from a dog dosed with i showed a broader spectrum of antibacterial activity than i itself, metabolites from this urine were isolated and partially characterized. the metabolites were mono- and dihydroxy-substituted species with the hydroxyl groups on carbons 4--7 of the hexahydrobenzisoxazole ri ...1979115987
partial characterization of anti-tumor effector macrophages in the peritoneal cavities of concomitantly immune mice and mice injected with macrophage-stimulating agents. 1979115998
[organ changes in rabbits in salmonellosis caused by salmonella agona]. 1978116344
peripheral gangrene in salmonella paratyphi septicaemia. 1979116403
[dynamics of the accumulation of the basic immunoglobulin classes in the intestinal contents in food toxinfections].the work presents the data on the dynamics of accululation of the main classes of immunoglobulins (a, g and m) in coprofiltrates obtained from patients with alimentary toxicoinfections (bacteriologically confirmed salmonellosis and diseases of unknown etiology). the levels of immunoglobulins of all classes (mainly iga and igg) were shown to be elevated in the process of the disease. the dynamics of the increase in the level of iga (both general and secretory) was supposed to indicate the formati ...1979116459
main pathway for mutagenic activation of 2-acetylaminofluorene by guinea pig liver homogenates. 1979116658
selective neutralization by antiinterferon globulin of macrophage activation by l-cell interferon, brucella abortus ether extract, salmonella typhimurium lipopolysaccharide, and polyanions. 1979116771
age-related defense against infection with intracellular pathogens.young adult (6--12 weeks old) and aged (20--24 months old) nmri mice were infected with various intracellular parasites. the following results were obtained: (1) after a sublethal infection with listeria monocytogenes, aged mice were found to show a resistance similar to that of young adults. a challenge infection with this pathogen was followed by specific immunity of long duration in both age-groups. (2) on the other hand, young animals were significantly more resistant to salmonella typhimuri ...1979116909
induction of bacteriolytic enzyme from pyocinogenic pseudomonas aeruginosa and its enzymatic properties.mitomycin c induced a pyocinogenic pseudomonas aeruginosa p15 to produce a bacteriolytic enzyme, pr1-lysozyme, together with pyocin r1. no significant accumulation of the enzyme was observed inside the induced cells. the enzyme was partially purified by acrinol treatment and amberlie cg-50 column chromatography. the mode of action of the enzyme on the host bacterial cells as well as on micrococcus lysodeikticus cells or peptidoglycan isolated from salmonella typhimurium, was compared with that o ...1978117282
mutagenicity of nitrosodiethanolamine on salmonella typhimurium.nitrosodiethanolamine was examined in the ames assay for bacterial mutagens. in absence of s9 activation a mutagenic effect was found.1979117355
mutagenicity tests with griseofulvin.griseofulvin was studied for its ability to induce structural chromosomal aberrations in germ and somatic cells of the male mouse. it was also tested for its capacity to produce his+ revertants in salmonella typhimurium. all tests yielded negative results, whereas highly significant effects were recorded in control assays with thio-tepa.1979117357
[survival of bacteria on zinc-coated and aluminum materials].the survival of st. aureus. e. coli, and of salmonellae was tested without any protein error and with it on new galvanized and with disinfection disturbed plate and compared with the survival of these microorganisms on new aluminous plate which was considered to be inert. the investigation by means of the impression method lasted for seven days. the growth of the microorganisms was evaluated according to the index of their survival. a distinct oligodynamic effect of the galvanized plate was prov ...1979117598
[certain results of infectious disease prevention in the german democratic republic].the history of the formation of the sanitary and hygienic service in the gdr is outlined with special reference to the friendly assistance of the ussr. the data on the morbidity dynamics in the gdr for the most important infectious diseases are presented for the 30-year period of the existance of the gdr. the role played by the system of immunoprophylaxis developed in the gdr in controlling infectious diseases, is shown and the immediate tasks presented, at increasing the effectiveness of this s ...1979117653
the clinical implications of contaminated pharmaceutical products. 1979117898
mutagenic and dna-damaging effects of n-alkyl-n-(alpha-acetoxyalkyl)nitrosamines, models for metabolically activated n,n-dialkylnitrosamines.mutagenic and dna-damaging effects of a series of n,n-dialkylnitrosamines monosubstituted at the alpha-carbon with an acetoxyl group were tested in salmonella typhimurium, escherichia coli, and bacilus subtilis in the absence of metabolic activation system. the compounds comprised 8 n-alkyl-n-(acetoxymethyl)nitrosamines (alkyl=methyl, ethyl, propyl, isopropyl, butyl, isobutyl, sec-butyl, or tert-butyl) and n-butyl-n-(1-acetoxybutyl)nitrosamine. all the compounds, except one with a tert-butyl gro ...1979118074
vinyl chloride--part 2: mutagenicity. 1979118101
surface k antigen in salmonella paratyphi b.it was established by agar immunoelectrophoresis that salmonella paratyphi b lysate contains a large number of soluble antigens which display a varying degree of serological specifity as well as different diffusion and electrophoretic mobility. salmonella paratyphi b was found to possess, apart from specific o and h antigens, a surface k antigen. this is a distinct antigen having strict serological specificity. purified k antigen displayed anodic mobility in immunoelectrophoresis. a detailed stu ...1979118212
mutagenicity and metabolism of dimethylnitrosamine and benzo[alpha]pyrene in tissue homogenates from inbred syrian hamsters treated with phenobarbital, 3-methylcholanthrene or polychlorinated biphenyls.there are significant differences between mice and hamsters in polycyclic hydrocarbon and nitrosamine metabolism. homogenates of liver, lung and intestinal mucosa from 6 strains of syrian golden hamster were compared for their ability to metabolize benzo[alpha]pyrene (bp) and dimethylnitrosamine (dmn) to mutagens. females of strains mha/sslak, lsh/sllak, cb/sslak, pd4/lak lhc/lak and lak:lvg (syr) were either untreated or received phenobarbital (pb), 3-methylcholanthrene (mc) or polychlorinated ...1979118380
effects of the hepatic s9 fraction from aroclor-1254-treated rats on the mutagenicity of benzo[alpha]pyrene and 2-aminoanthracene in the salmonella/microsome assay.the mutagenicity of benzo[alpha]pyrene and 2-aminoanthracene for salmonella typhimurium ta98 in the plate-incorporation test was studied using liver s9 from untreated and aroclor-1254-treated rats. the induction of liver s9 protein, arylhydrocarbon hydroxylase (ahh), and cytochrome p448/450 was followed with time. there was no change in protein concentrations with induction; ahh and cytochrome levels were increased at 1, 3, 5 and 7 days post aroclor treatment. benzo[alpha]pyrene mutagenicity was ...1979118381
studies on the mutagenicity of p-phenylenediamine in salmonella typhimurium. presence of pcb's in rat-liver microsomal fraction induced by aroclor.the mutagenicity of fresh solutions of p-phenylenediamine (ppd) and aroclor 1254 was investigated. the histidine-requiring strains of salmonella typhimurium were used in the absence and presence of uninduced and/or aroclor-induced rat-liver homogenate. the presence of polychlorinated biphenyls (pcbs) was also examined by chromatographic methods in aroclor-induced rat-liver homogenate. in the absence of metabolic activation, as well as in the presence of uninduced rat-liver homogenate, ppd was no ...1979118383
[splenic abcess due to salmonella paratyphi a]. 1979118434
[modifications by nematoda of the sensitivity of mice to salmonella abortus ovis administered orally or subcutaneously].mice inoculated 6 to 9 days previously with heligmosomoides polygyrus (=nematospiroides dubius) become more frequently infected than controls after an oral challenge with a constant dose of salmonella abortus ovis. but parasitism increases the ld 50 when the subcutaneous route of infection is used, probably by stimulating the immune system of the host.1979118826
magnetic susceptibility of microorganisms.total magnetic susceptibility of 13 species and varieties of bacteria was investigated using the relative method of guy. it has been established that the index of magnetic susceptibility is a constant characteristic of bacteria. total magnetic susceptibility ranged from --0.3295.10(-6) in escherichia p678 to --0.4965.10(-6) in proteus. it has also been established that magnetic susceptibility changes during long-term passages of bacteria in fluctuating +/- 0.1 oe) magnetic field. this is suggest ...1979118995
bacteriology of rattlesnake venom and implications for therapy.although the incidence of infection secondary to the bites of venomous snakes remains unknown, the routine use of prophylactic antimicrobial therapy is advocated. in this study, the venom from 15 rattlesnakes was cultured, and 58 aerobic and 28 anaerobic strains of bacteria were isolated. the most common species isolated were pseudomonas aeruginosa, proteus species, coagulase-negative staphylocci, and clostridium species. bacteroides fragilis was also recovered. when the fang sheaths of four add ...1979119002
biological effects of magnetic fields: studies with microorganisms.five bacteria and one yeast were grown in magnetic fields of 50-900 gauss with frequencies of 0-0.3 hz and square, triangular, or sine waveform. growth of these microorganisms could be stimulated or inhibited depending upon the field strength and frequency of the pulsed magnetic field. spore germination and mutation frequency were unaffected by the magnetic fields used in this study.1979119572
the relationship between the protective and cross-reacting antigens of brucella spp., yersinia enterocolitica 0:9 and salmonella serotypes of kauffmann-white group n.vaccination with killed cells of brucella abortus, yersinia enterocolitica 0:9 and salmonella neusdorf evoked cross-reacting antibodies in guinea pigs but only the homologous antigen effectively produced protective immunity to br. abortus. none of these preparations induced protective immunity to y. enterocolitica in gerbils but all stimulated protective immunity to s. landau in balb/c mice. the antigenic determinants responsible for protective immunity to salmonella infection were located on th ...1979119612
in vitro studies on the carcinogenic potential of orthodontic bonding materials. 1979119625
distribution of membrane-bound monoamine oxidase in bacteria.the distribution of membrane-bound monoamine oxidase in 30 strains of various bacteria was studied. monoamine oxidase was determined by using an ammonia-selective electrode; analyses were sensitive and easy to perform. the enzyme was found in some strains of the family enterobacteriaceae, such as klebsiella, enterobacter, escherichia, salmonella, serratia, and proteus. among strains of other families of bacteria tested, only pseudomonas aeruginosa ifo 3901, micrococcus luteus ifo 12708, and brev ...1979120132
experimental syphilis in the rabbit: passive transfer of immunity with immunoglobulin g from immune serum.a preparation of immunoglobulin g isolated from a pool of immune sera derived from rabbits with long-term syphilis was shown to possess a high degree of purity as judged by immunodiffusion and protein electrophoresis. the antitreponemal power of the preparation of immunoglobulin g and that of the immune serum pool from which it was derived were found to be equivalent in both the skin protection and the systemic protection test. the observation that neither normal serum nor a pool of serum derive ...1979120386
immunological responses of fluke-infected and fluke-free cattle to salmonella dublin and other antigens.immune responses to heat-killed brucella abortus strain 19 and to ovalbumin were compared in 15 fluke-infected and 15 fluke-free friesian heifers. b abortus was injected 16 weeks and ovalbumin 19 weeks after the oral administration of 1000 metacercariae of fasciola hepatica. agglutinating antibody responses to b abortus were similar in both groups. immediate type hypersensitivity to ovalbumin was apparently suppressed in fluke-infected animals when assessed by active and passive cutaneous anaphy ...1979120572
[experimental salmonella infection under the effect of ionizing radiation]. 1979120601
[importance of respiratory route in experimental salmonellosis in balb/c mice].infection of mice with s. typhimurium, was conducted by respiratory, oral and peritoneal routes. the results obtained showed that infection occurred more quickly by i. p. than by other routes. however i. n. inoculation is the more efficient concerning bacteria concentration per mousse to obtain the dl 100. a study of salmonella growth in vivo was conducted in lungs, spleen, liver and blood. the results are discussed in relation to the calf respiratory salmonellosis actually observed.1979120783
salmonella choleraesuis proteins and their relation to proteins from bacteria of heterologous sero-groups.a diversity of proteins was identified in the material isolated from s. choleraesuis with the help of sera prepared in rabbits with this material. the sera displayed, in agar-gel diffusions, numerous superimposed precipitation lines against proteins from: salmonellae, shigellae and e. coli. in contrast to proteins from s. paratyphi c, sharing identical identical 'o' 'factors, the serological activity of the s. choleraesuis proteins was impaired by heating. the immunochemical analysis of the sera ...1979120926
development of specific cellular immunoreactivity in typhoid fever.development of cellular immunoreactivity to salmonella typhi and salmonella paratyphi-a was studied by the leukocyte migration inhibition test in 9 patients with typhoid fever and in 2 patients with paratyphoid fever. cellular reactivity could be demonstrated from the first days of the disease in all the subjects. the most pronounced migration inhibition was observed during the febrile period. it is suggested that specific cellular reactivity may play a pathogenetic role in typhoid fever.1979121028
a comparison of the genotoxic properties of tris(2,3-dibromopropyl)phosphate and tris(1,3-dichloro-2-propyl)phosphate in a battery of short-term bioassays. 1979121137
mutagenicity of skin tanning lotions.two lotions that tan skin in the absence of sunlight and their active ingredient, dihydroxyacetone (dha), are mutagenic in salmonella typhimurium strain ta100 without metabolic activation. however, addition of s-9 mix that contains aroclor 1254-induced rat hepatic microsomes enhances significantly the mutagenic activity of all three agents. both lotions and dha also cause primary dna damage as determined by the rec-assay in bacillus subtilis. the potential human health hazard of these lotions is ...1979121138
[biological action of triton x-100 on pathogenic bacteria]. 1979121195
differential mutagenicities of triamino benzenes against salmonella typhimurium ta98 in the presence of s9 fractions from polychlorinated biphenyls-, phenobarbital- or 3-methylcholanthrene-pretreated rats, hamsters and mice.mutagenicity of 6 aminobenzene derivatives against salmonella typhimurium ta98 was studied in the presence of various s9 fractions. s9, which has been prepared form the livers of rats, hamsters and mice after pretreatment with different types of inducers; polychlorinated biphenyls, phenobarbital and 3-methylcholanthrene, was used as the methabolic activating enzyme in this mutation assay. the s9 fractions from 3-methylcholanthrene-treated rats and mice are most useful for mutation induction by t ...1979121315
[salmonella infections in the province of frosinone in the period 1974-1978].835 isolates for samonellae have been obtained from more than 32,000 stool cultures carried out on healthy persons living in the frosinone district during 1974-1978. the strains typed were 786 and any of more than 37 serotypes have been identified. s. wien showed the highest incidence.1979121686
protection of mice against babesia microti with cord factor, coam, zymosan, glucan, salmonella and listeria.cord factor (trehalose 6-6' dimycolate). coam (chlorite-oxidized oxyamylose), zymosan, glucan, salmonella enteritidis 11rx and listeria monocytogenes were found to protect mice against subsequent infection with babesia microti, an intra-erythrocytic protozoan parasite. this protection was not observed after injection of staphylococcus epidermidis, a viridans group streptococcus, thioglycollate, or colloidal carbon. all the agents which protect against b. microti have also been reported to induce ...1979121772
present and future uses of mutagenicity tests for assessment of the safety of food additives.the tier approach has been employed for the past 3 years for investigating the potential mutagenicity of food additives and generally recognized as safe (gras) substances. this approach is used to set testing priorities, since a large number of substances must be investigated. three tiers or testing levels are used. the first tier is a pre-screen to determine whether a chemical has the potential to cause genetic damage. the second tier is designed to ascertain whether mutagenic activity detected ...1977121932
[antigenic relationships between salmonella choleraesuis strains and torulopsis (author's transl)].antigenic relationships between candida clausseni and salmonella choleraesuis were presented before. in this study, antigenic relationships between salmonella choleraesuis and different strains of torulopsis analyzed by immunodiffusion studies. antigenic relationships between intragroups of torulopsis were also studied. the results showed that the common thermostable component (s) of s. choleraesuis and torulopsis musae may probably be related to the common enterobacterial antigen. other results ...1979122004
[distribution of different phage types of s. paratyphi b in spain]. 1979122277
isolation of salmonella and pseudomonas aeruginosa from seawater with different levels of pollution in rio de janeiro. 1979122385
[comparative study of microbial methods for the detection of genetic toxicity].it is important to have a rapid and accurate method to detect the toxic action of drugs and chemical compounds used by man. a comparative study with two microbial systems was carried out: one using salmonella typhimurium and the other using bacillus subtilis. the 1-8-dihydroxyantraquinone was the tested drug and the n-methyl-n'-nitro-n-nitrosoguanidine and the 2-aminofluorene were used as control substances. these compounds were used as such or after previous transformation by a microsomal syste ...1979122387
piperacillin, a new penicillin active against many bacteria resistant to other penicillins.the in vitro activity of piperacillin, a new semisynthetic piperazine penicillin derivative, was evaluated against 626 clinical isolates and compared with the activity of other beta-lactam antibiotics. at a concentration of 0.1 microgram/ml, piperacillin inhibited all streptococci except enterococci. non-beta-lactamase-producing staphylococci were inhibited by 1.6 microgram or less per ml. both beta-lactamase- and non-beta-lactamase-producing haemophilus were inhibited by 0.1 microgram/ml. piper ...1978122519
t mitogens trigger lps responsiveness in mouse thymus cells.mouse thymus cells are essentially unresponsive to lipopolysaccharide (lps) stimulation. however, when cultured with minimally mitogenic levels of concanavalin a or submitogenic ratios of mitomycin-treated allogeneic spleen cells, in combination with lps, they demonstrate levels of dna synthesis de novo or greater than those induced by the t cell mitogen alone. dose-response kinetics were characteristic of lps. the subpopulation containing the lps responsive cells was of low net buoyant density. ...1975122988
typhoid cardiac involvement.three cases of typhoid cardiac complications are reported. salmonella typhi was the aetiological agent in all three; the discovery of 3 patients over a period of 18 months merits special interest, especially since typhoid fever is endemic in the area concerned. the significance of the complication reported here is further enhanced by absence of similar specific cases in the english literature dealing with cardiac salmonellosis. one of the cases described in this article, the only fatality of the ...1975123083
requirement for macrophages in lipopolysaccharide-stimulated mixed thymocyte cultures. 1975123174
transfection of escherichia coli spheroplasts. v. activity of recbc nuclease in rec+ and rec minus spheroplasts measured with different forms of bacteriophage dna.the in vivo activity of the recbc nuclease was assayed by transfection of isogenic rec+ and rec minus spheroplasts with bacteriophage dna of various origin and structure. the results indicate that the recbc nuclease can limit transfection at several stages during the production of an infective center; such limitations depend primarily on whether the dna is in, or assumes, a nuclease-sensitive structure. the first stage of limitation can occur when a nuclease-sensitive transfecting molecule enter ...1975123277
[current status of enteric infections]. 1975123454
[epidemiology, terminology and statistical classification of intestinal infections].on the basis of critical survey of literature data and analysis of morbidity of intestinal infections in 5 towns of donbass for 20 years and also of studying 5148 case histories an attempt is made of rational explantation of the causes of growth during the last years of the incidence of sonne dysentery salmonelloses, escherichioses and other diseases caused by conditionally-pathogenic microorganisms. the importance of improvement of nomenclature and of statistical classification of intestinal in ...1975123681
the effect of various amine-depleting drugs on the fever response exhibited by rabbits to bacterial or leucocyte pyrogen.1 the concentration of noradrenaline, dopamine and 5-hydroxytryptamine (5-ht) in the rabbit brainstem was measured during fevers produced by either an injection of bacterial pyrogen (bp) or continuous infusion of leucocyte pyrogen (lp). 2 both procedures had little effect on the concentration of noradrenaline in the preoptic/hypothalamic area but significantly (p smaller than 0.001) lowered the concentration of noradrenaline in the midbrain and pons/medulla. 3 bp significantly (p smaller than 0. ...1975123804
major changes in lymphocyte proliferation evoked by activated macrophages. 1975123831
subunit composition, function, and spatial arrangement in the ca2+-and mg2+-activated adenosine triphosphatases of escherichia coli and salmonella typhimurium. 1975124154
Displaying items 501 - 600 of 70497