| the activity of salmonella phage p22 gene 24 product in escherichia coli. | | 1978 | 208254 |
| alteration of the ability of liver microsomes to activate n-2-fluorenylacetamide to a mutagen of salmonella typhimurium during hepatocarcinogenesis. | | 1978 | 208764 |
| identification of some metabolic products of 5' -deoxy-5' -s-isobutylthioadenosine, an inhibitor of virus-induced cell transformation. | 5' -deoxy-5' -s-isobutylthioadenosine (ibus)5' ado has been shown to be rapidly degraded to 5-deoxy-5-s-isobutylthioribose and adenine in procaryotes. in chick embryo fibroblasts there are two metabolic pathways for (ibus)5' ado degradation: (a) oxidative deamination into 5' -deoxy-5'-s-isobutylthioinosine (the main product) and (b) hydrolysis into 5-deoxy-5-s-isobutylthioribose plus adenine. the latter reaction is not due to bacterial contamination, since the same results were obtained under st ... | 1978 | 208841 |
| noncultivable viruses and neonatal diarrhea: fifteen-month survey in a newborn special care nursery. | during a 15-month period of surveillance, diarrhea developed in 257 of 913 babies (28%) admitted within 2 hours of birth to a special care nursery in melbourne, australia. diarrhea was seasonal, affecting a maximum of 43% of babies admitted during one winter month (july) and a minimum of 13% of babies admitted during one summer month (december). diarrhea was no more frequent nor more severe in babies of very low birth weight or of very early gestational age. two noncultivable viruses were locate ... | 1978 | 209058 |
| new and old agents in diarrhea: a prospective study of an indigenous adult african population. | we conducted a prospective study 77 indigenous african adults with acute diarrhea seeking care at the major hospital in nairobi, kenya, to determine the major pathogens responsible for this syndrome in adults. fecal and blood specimens were collected and examined for enteric bacterial pathogens, viruses, and parasites. in 13 (26%) inpatients and 11 (49%) outpatients shigella was found, and heat-labile and heat-stable forms of enterotoxigenic escherichia coli were found in 9 (18%) inpatients and ... | 1978 | 209697 |
| travelers' diarrhea among united states marines in south korea. | a battalion of united states marines traveling to south korea in the spring of 1976 was studied to determine the incidence and etiology of gastroenteritis. during the three weeks they visited south korea, 21% of 694 marines developed diarrhea. stool and serum specimens collected before, during, and after their stay were examined for evidence of infection with salmonella, shigella, and vibrio species, enterotoxigenic and invasive escherichia coli, reovirus-like agent (rvla), and intestinal ova an ... | 1978 | 210660 |
| prospective study of enteropathogens in children with diarrhea in houston and mexico. | during a 22-month period, 595 children with diarrhea and 210 age-matched controls attending clinics in houston (367 children) and mexico (438) were prospectively evaluated for enteric pathogens. enteropathogens associated with disease were shigella (18%), rotavirus (14%), salmonella (9%), toxigenic escherichia coli (6%), and others (12%), including 14 proteus isolates that caused rounding of adrenal cells. enteropathogens were isolated from a greater (p less than 0.001) number of children with d ... | 1978 | 211215 |
| carbamoyl-phosphate synthetase (glutamine): salmonella. | | 1978 | 211376 |
| phosphoribosylpyrophosphate synthetase (ribose-5-phosphate pyrophosphokinase) from salmonella typhimurium. | | 1978 | 211378 |
| nucleoside diphosphokinase from salmonella typhimurium. | | 1978 | 211385 |
| the potential carcinogenicity of methyl fluorosulphonate (ch3oso2f;magic methyl). | | 1978 | 211408 |
| metabolism of bromobiphenyls. | | 1978 | 212083 |
| foodborne hazards of microbial origin. | foods can serve as vehicles of many pathogenic and toxigenic agents of disease. bacterial agents comprise three groups: 1) those that grow in the food and produce an active toxin before consumption (e.g., clostridium botulinium); 2) those that merely exist as contaminants in the food but are able to initiate infection when swallowed (e.g., salmonella spp.); and 3) those that multiply and produce large numbers of vegetative cells in the food, then release an active enterotoxin when they sporulate ... | 1978 | 212326 |
| panel report on the colloquium on selected diarrheal diseases of the young. | | 1978 | 212391 |
| physiology of diarrhea--large intestine. | | 1978 | 212413 |
| the adrenal response to exogenous adrenocorticotrophin in patients with infections due to neisseria meningitidis. | the adrenal response to a soluble form of beta1-24-corticotropin (tetracosactrin [acth]: 250 microgram administered intramuscularly) was studied in 28 patients with meningitis due to neisseria meningitidis (21 with petechiae and seven without) and in six patients with salmonella typhi bacteremia. six normal subjects also were tested for adrenal responsiveness at four different times of the day (8 a.m., 12 noon, 4 p.m., and 10 p.m.) and served as controls. the results showed that, whatever the ti ... | 1978 | 212489 |
| diseases transmitted from pets to man: an evolving concern for veterinarians. | pets are not a major source of human infections but they can transmit certain diseases to man. this transmission usually is complex, requiring close contact with pets or their excretions and frequently involves a breach of sound hygienic practice. in some instances, pathogens of animal origin are acquired inadvertently because infectivity can persist after evidence of gross contamination has gone. veterinarians participate in controlling zoonotic diseases by encouraging rabies vaccination and h ... | 1978 | 213237 |
| concurrent rotavirus and salmonella infections in foals. | | 1978 | 213413 |
| absence of cytotoxic effect of selected pathogens on hla b27 positive fibroblasts. | | 1978 | 213785 |
| woodrige memorial lecture. the veterinary profession and an intensive poultry industry. | | 1978 | 213871 |
| failure of mecillinam and pivmecillinam to eradicate convalescent carriage of salmonellas. | | 1978 | 214204 |
| [inner membrane structures and the electron paramagnetic resonance spectra of salmonella typhimurium cells after their interaction with nitroso compounds]. | | 1978 | 214672 |
| [infectious causes of perinatal mortalities in ruminants (author's transl)]. | the advantages and disadvantages of the different diagnostic techniques e.g. pathological and microbiological studies, immunoglobulin and specific antibody determinations and fluorescent antibody studies in relation to these mortalities are discussed. the most important pathological lesions in the placentas and foetuses are described. | 1978 | 215769 |
| enteropathogenic organisms. new etiologic agents and concepts of disease. | | 1978 | 215856 |
| food-borne disease. i. | | 1979 | 215944 |
| utilization of d-xylose by wild-type strains of salmonella typhimurium. | enzyme studies of strains of salmonella typhimurium representing biotypes that utilized d-xylose rapidly (xylose strong) or slowly (xylose weak) showed that they were different in the utilization of d-xylose because the xylose-weak strains were deficient in the transport of d-xylose. this observation is consistent with the idea that strains of the different xylose-weak biotypes, e.g. biotypes 17 to 32, were descended from strains of xylose-strong types, particularly from biotype 1. | 1979 | 216662 |
| gastroenteritis: etiology, pathophysiology and clinical manifestations. | the infectious etiologic agents of gastroenteritis are manifold and have only recently been studied in greater depth. part of the problem in studies pertaining to diarrhea is the difficulty in identifying fecal "pathogens" among an enormous number of indigenous fecal microorganisms. finally, the recognition of the pathogenicity of enterotoxins has created an awareness of the complexity of gastrointestinal physiology with host-parasite interactions. | 1979 | 216878 |
| 5-fluoroorotate-resistant mutants of salmonella typhimurium. | spontaneously occurring mutants of salmonella typhimurium resistant to 5-fluoroorotate (5-foa) were isolated. one class of mutant showed marked derepression of pyrimidine biosynthetic enzymes and had the unusual property of being unable to grow on nutrient agar. however, when the osmotic strength of nutrient agar was increased, the mutants were able to grow. the genetic basis for the osmotic fragility and elevated pyr enzyme synthesis was the result of mutations affecting pyrh, encoding the enzy ... | 1978 | 217514 |
| study on the mutagenicity of conjugated estrogens in human, animal and bacterial systems. | conjugated estrogens were studied for mutagenicity (and implied carcinogenicity) in two strains of s. typhimurium, two normal and three neoplastic human lymphoid cell lines (the latter from burkitt's lymphoma patients) in cell culture and a chinese hamster cell line in diffusion chambers implanted into mice. no significant increase in mutation rate or chromosome aberrations were noticed after exposure to conjugated estrogens. | 1978 | 217940 |
| immunochemical analysis of membrane vesicles from escherichia coli. | membrane vesicles isolated from escherichia coli ml 308--225 have been analyzed by crossed immunoelectrophoresis, and immunoprecipitates corresponding to the following cellular components have been identified: atpase (ec 3.6.1,3), two or three nadh dehydrogenases (ec 1.6.99.3), d-lactate dehydrogenase (ec 1.1.1.27), glutamate dehydrogenase (ec 1.4.1.4), dihydro-orotate dehydrogenase (ec 1.3.3.1), 6-phosphogluconate dehydrogenase (ec 1.1.1.43), polynucleotide phosphorylase (ec 2.3.7.8), beta-gala ... | 1979 | 218620 |
| synthesis of adenosine 3':5'-cyclic monophosphate in salmonella typhimurium growing in continuous culture. | | 1979 | 219134 |
| effects of cyclic amp altering drugs on endotoxin-induced termination of pregnancy. | the effects of dibutyryl-cyclic amp (dbcamp), propranolol, and theophylline on endotoxin (lps) challenged pregnant mice was determined by comparing the patterns of termination and times of fetal expulsion. endotoxin isolated from wild type (wt) and re chemotype mutant cells of salmonella typhimurium was used. wild type lps caused the expulsion of the fetuses, while re lps primarily caused the resorption of the fetuses. the major change in pattern occurred in the propranolol treated re lps challe ... | 1979 | 219454 |
| pyridine nucleotide cycle of salmonella typhimurium: isolation and characterization of pnca, pncb, and pncc mutants and utilization of exogenous nicotinamide adenine dinucleotide. | mutants of salmonella typhimurium lt-2 deficient in nicotinamidase activity (pnca) or nicotinic acid phosphoribosyltransferase activity (pncb) were isolated as resistant to analogs of nicotinic acid and nicotinamide. information obtained from interrupted mating experiments placed the pnca gene at 27 units and the pncb gene at 25 units on the s. typhimurium lt-2 linkage map. a major difference in the location of the pnca gene was found between the s. typhimurium and escherichia coli linkage maps. ... | 1979 | 220211 |
| travelers' diarrhea among u.s. army troops in south korea. | a prospective study of diarrhea was conducted among 98 u.s. army soldiers during their first six weeks in south korea. diarrhea developed in 54 (55%) of 98 soldiers and had a mean duration of five days. infections with salmonella, shigella, vibrio, enterotoxigenic escherichia coli, enteroviruses, and intestinal parasites were uncommon. four (8%) of 50 soldiers with documented diarrhea, two (6%) or 32 with a history of diarrhea, and one (3%) of 29 who denied gastrointestinal symptoms had serologi ... | 1979 | 220334 |
| phagolysosome formation, cyclic adenosine 3':5'-monophosphate and the fate of salmonella typhimurium within mouse peritoneal macrophages. | salmonella typhimurium did not inhibit fusion of lysosomes with the phagocytic vacuoles in infected macrophages and caused no increase in cyclic adenosine 3':5'-monophosphate. glutaraldehyde-killed bacteria showed rapid ultrastructural degeneration within the phagolysosomes. in contrast, untreated bacteria were resistant to digestion by lysosomal enzymes. intracellular survival of this species appears to depend on resistance to, and not evasion of, lysosomal enzymes. | 1979 | 220378 |
| alcohol-related diseases and carcinogenesis. | possible mechanisms whereby alcohol abuse and alcohol-related diseases may promote the development of cancer are analyzed. the mechanisms discussed include: (a) contact-related local effects on the upper gastrointestinal tract; (b) the presence of low levels of carcinogens in alcoholic beverages; (c) induction of microsomal enzymes involved in carcinogen metabolism; (d) various types of cellular injury produced by ethanol and its metabolites and their relationship to cancer, particularly in the ... | 1979 | 221110 |
| etiology of infantile enteritis in south africa. | infantile enteritis constitutes a major health problem in developing countries. several investigations into the etiology of this condition among various south african populations have been undertaken during the past few years. recent studies of black urban infants have revealed that salmonellae, shigellae, enterotoxigenic enterobacteriaceae, and rotaviruses play a relatively minor role in infantile enteritis. on the other hand, all studies, including a number performed several years ago, have de ... | 1979 | 221438 |
| migration of epithelial cells in the small intestine of mice perorally infected with coxsackievirus b5. | the rate of cell migration in the small intestine during enteric viral infections has not been assessed previously. cd-1 mice (33 days old) were infected perorally with 1.0 x 10(8) plague-forming units of coxsackievirus b5 and 12 hr later were injected intraperitoneally with 2 micron ci of [3h]thymidine/g of body weight. after 2, 12, 24, 48, 60, and 72 hr, mice were killed, and the small intestine was removed. specimens obtained at each interval were examined by radioautography; similar specimen ... | 1979 | 221595 |
| [broad-spectrum disinfectants]. | | 1979 | 222042 |
| [infectious bronchitis and pullorum disease in chickens]. | | 1979 | 222043 |
| human enteroviruses in oysters and their overlying waters. | the presence of enteroviruses in oysters and oyster-harvesting waters of the texas gulf coast was monitored over a period of 10 months. viruses were detected in water and oyster samples obtained from areas both open and closed to shellfish harvesting. viruses were detected periodically in waters that met current bacteriological standards for shellfish harvesting. no significant statistical relationship was demonstrated between virus concentration in oysters and the bacteriological and physiochem ... | 1979 | 222210 |
| survival of bacteria in carcasses. | bacteria injected into the bloodstream of guinea pigs shortly before death decreased in number in carcass tissues for about 1 h after death. if initial bacterial numbers were sufficiently low, all bacteria were eliminated, and carcass tissues were sterile 24 h after death. carcass tissue sterility was maintained with an initial density of clostridium perfringens or salmonella typhimurium of 20 cells per g or with an initial density of the other species examined of several hundred cells per gram. ... | 1979 | 222211 |
| kinetic and magnetic resonance studies of the interaction of the cr-atp complex with phosphoribosylpyrophosphate synthetase from salmonella typhimurium. | | 1979 | 222212 |
| magnetic resonance studies of the anthranilate synthetase-phosphoribosyltransferase enzyme complex from salmonella typhimurium. | | 1979 | 222217 |
| [stress and immunity in cattle]. | stress of variable length may be caused in calf by parenteral administration of supercortisol and application of acute thermal load. hormonal or thermal stress may have negative impact on postvaccinal immunity to paratyphoid (salmonella dublin 81), as may be interpreted with reference to the o-agglutination titre of blood serum. the extent to which immunity is suppressed by stress was found to depend on the moment of stress application, duration of stress, and age of the calf. | 1979 | 222226 |
| pyridine nucleotide cycle of salmonella typhimurium: regulation of nicotinic acid phosphoribosyltransferase and nicotinamide deamidase. | nicotinic acid phosphoribosyl transferase (naprtase) and nicotinamide deamidase activities from salmonella typhimurium were examined regarding their regulation by either feedback inhibition or repression mechanisms. the results indicate that neither enzyme is subject to feedback inhbition. nicotinamide deamidase does not appear to be under repression control. naprtase, however, is repressed when cells are grown in minimal medium supplemented with various intermediates of the pyridine nucleotide ... | 1979 | 222729 |
| uptake and catabolism of d-xylose in salmonella typhimurium lt2. | salmonella typhimurium lt2 grows on d-xylose as sole carbon source with a generation time of 105 to 110 min. the following activities are induced at the indicated time after the addition of the inducer, d-xylose: d-xylulokinase (5 min), d-xylose isomerase (7 to 8 min), and d-xylose transport (10 min). all other pentoses and pentitols tested failed to induce isomerase or kinase. synthesis of d-xylose isomerase was subject to catabolite repression, which was reversed by the addition of cyclic aden ... | 1979 | 222731 |
| genetics and regulation of d-xylose utilization in salmonella typhimurium lt2. | twenty-one xyl- mutants of salmonella typhimurium were selected: all had lost one or more of the activities for d-xylose isomerase, c-xylulokinase, or d-xylose transport. the mutants were classified into five functional groups: xylr, pleiotropic negative (12 mutants); xyla, d-xylose isomerase defective (3 mutants); xylb, d-xylulokinase defective (2 mutants); xylt, d-xylose transport defective (1 mutant); and 3 mutants with defective d-xylose isomerase and d-xylulokinase. some nonsense mutations ... | 1979 | 222732 |
| arylsulfatase in salmonella typhimurium: detection and influence of carbon source and tyramine on its synthesis. | arylsulfatase synthesis was shown to occur in salmonella typhimurium lt2. the enzyme had a molecular weight of approximately 50,000 and was separated into five forms by isoelectrofocusing. the optimal ph for substrate hydrolysis was ph 6.7, with michaelis constants for nitrocatechol sulfate and nitrophenyl sulfate being 4.1 and 7.9 mm, respectively. enzyme synthesis was strongly influenced by the presence of tyramine in the growth medium. the uptake of [14c]tyramine and arylsulfatase synthesis w ... | 1979 | 222733 |
| decreased binding of polymyxin by polymyxin-resistant mutants of salmonella typhimurium. | polymyxin-resistant pmra strains were shown to absorb only about 25% of the amount of polymyxin absorbed by the corresponding polymyxin-sensitive parent strains. the lipopolysaccharide from the pmra strains bound less polymyxin than the lipopolysaccharide from the parent strains. | 1979 | 222738 |
| generation of cytotoxic lymphocytes against human tumor cells in vitro by various soluble microbial extracts. | | 1979 | 222929 |
| depression of spontaneous and ionophore-induced neurotransmitter release by salmonella. | exposure of frog neuromuscular junctions to heat-killed, lyophilized salmonella typhimurium (sr 11) produces an early increase in spontaneous transmitter release followed by depression of release and blockade of the obligatory release usually induced by ionophore x537a. | 1979 | 223876 |
| oral rehydration and maintenance of children with rotavirus and bacterial diarrhoeas. | the outcome of administering ort (oral rehydration therapy) to 62 infants admitted to a costa rican hospital with acute rotavirus or bacterial diarrheas and with 5-10% dehydration was described. 94% of the infants were successfully treated by administering only ort. there were no significant differences in the success rates for rotavirus diarrhea patients and for various bacterial diarrhea patients. success rates were 92% for rotavirus patients, 93% for escherichia coli patients, 96% for idio ... | 1979 | 225048 |
| [seromonitoring of laboratory mouse and rat colonies for common murine pathogens (author's transl)]. | during a period from 1973 to 1978, 392 and 225 lots including 12,232 mouse and 8,044 rat individual sera, respectively, were examined for antibodies to murine hepatitis virus, sendai virus, bordetella bronchiseptica, mycoplasma pulmonis, tyzzer agents, salmonella typhimurium and corynebacterium kutscheri. of mouse lots 94.5% and 39.3% from breeder and user colonies, respectively, were negative for all antibodies examined as well as 31.6% and 17.2% of rat breeder and user colonies, respectively. ... | 1979 | 225183 |
| [mass food poisoning of bacterial etiology in poland in the years 1973-1976]. | | 1979 | 225759 |
| steady-state investigations of the mechanism of histidinol dehydrogenase. | initial velocities of the histidinol dehydrogenase reaction (ec 1.1.1.23) were measured as a function of the concentrations of the substrates histidinol and nad+ and in the presence and absence of the product nadh. the data are consistent with a bi uni uni bi ping pong mechanism. the kinetic constants of this mechanism were determined; km for histidinol was found to be 14 microm and for nad+ 0.7 mv; ki for nad+ was 0.4 mm. | 1979 | 226079 |
| interaction of divalent cations and polymyxin b with lipopolysaccharide. | | 1979 | 226126 |
| effect of silica on the innate resistance of inbred mice to salmonella typhimurium infection. | the role of macrophages in the innate immunity of (cba/n female x dba/2n male)f1 female mice to salmonella typhimurium was assessed with silica, an agent which has been reported to selectively inactivate macrophages. silica, administered intravenously to mice, markedly decreased the phagocytic capacity of splenic macrophages but had no effect on splenic responsiveness to the b-cell mitogen lipopolysaccharidide or the t-cell mitogen phytohemagglutinin, nor did it affect the frequency of surface i ... | 1979 | 226477 |
| human rotavirus in an adult population with travelers' diarrhea and its relationship to the location of food consumption. | the role of human rotavirus in adult diarrhea was evaluated in 164 newly arrived us students attending summer school at an urban mexican university. rotavirus was identified in stool samples by electron microscopy. rotavirus was found in 26 of 109 students with diarrhea (24%) and in 8 of 55 asymptomatic control students (15%). although bacterial pathogens were recovered from virus positive students with diarrhea, viral shedding also occurred independently of other agents. clinical disease in stu ... | 1979 | 226656 |
| thin-layer chromatographic methods to isolate 32p-labeled 5-phosphoribosyl-alpha-1-pyrophosphate (prpp): determination of cellular prpp pools and assay of prpp synthetase activity. | | 1979 | 227291 |
| [acute infectious gastroenteritis. etiology and its correlation with clinical manifestations and fecal mucus]. | 343 children with acute diarrhea were studied from january 1976 to september 1977. rotavirus was the agent most frequently isolated (18 per cent) followed by shigella (12 per cent) and salmonella (10 per cent). enterotoxigenic e. coli was identified in 8 per cent and invasive e. coli only in two cases. 80 per cent of isolated rotavirus fell in the neonate group and 25 per cent in the infant group. diarrhea caused by rotavirus had a short duration, fever was negligible and abundant liquid stools ... | 1979 | 227338 |
| mutagenic testing of diethylhydroxylamine, nitroethane, and diethylamine hydrogen sulfite. | | 1979 | 227678 |
| prenatal influence on immunocompetence of the neonate. | | 1979 | 227826 |
| phylogenetic relationships between different d-xylose biogroups in wild-type salmonella typhimurium strains and a suggested evolutionary pathway. | | 1979 | 227827 |
| new function for high density lipoproteins. their participation in intravascular reactions of bacterial lipopolysaccharides. | the addition of bacterial lipopolysaccharide (lps) from escherichia coli 0111:b4 or salmonella minnesota r595 to plasma (or serum) resulted in a marked reduction of the hydrated buoyant density of the parent lps (0111:b4 [d = 1.44 g/cm3] and r595 [d = 1.38 g/cm3]), to d less than 1.2 g/cm3. this reduction in buoyant density to less than 1.2 g/cm3 of the lps required plasma (or serum) lipid. delipidation of plasma (or serum) by extraction with n-butanol/diisopropyl ether (40/60, vol:vol) prevente ... | 1979 | 227936 |
| [biological activity of bordetella and salmonella endotoxins]. | | 1979 | 228129 |
| changes in the activities of enzymes, especially lactate dehydrogenase, in endotoxin-poisoned mice. | | 1979 | 228162 |
| [salmonella osteomyelitis (authors transl)]. | a case of osteomyelitis due to salmonella dublin is reported by the authors who underline the features which distinguish this affection from typhous osteomyelitis, which is completely different. | 1979 | 228429 |
| [microbial emission, immission and changes in the germ count in the cooling water during operation of wet cooling towers ii. communication: measuring methods, emission values and changes in the germ count in the cooling system (author's transl)]. | the second in the series "microbial emission, immission and changes in the germ count in the cooling water of wet cooling towers" describes measuring methods and results of the measurements for determining the emission values and the changes in the germ count in the cooling system. the content of colony-forming units (kbe) in the cooling water varied widely, depending on the germ content of the surface water and the preparation of the cooling water (filtration, chemical conditioning). in summer ... | 1979 | 228514 |
| degradation of mutagens from pyrolysates of tryptophan, glutamic acid and globulin by myeloperoxidase. | | 1979 | 228669 |
| inhibitors for the mutagenicities of colon carcinogens, 1,2-dimethylhydrazine and azoxymethane, in the host-mediated assay. | inhibitory effects of several chemicals on the mutagenicities of 1,2-dimethylhydrazine (dmh) and azoxymethane (aom) for salmonella typhimurium g46 in the host-mediated assay were investigated. they were carbon disulfide (cs2), tetraethylthiuram disulfide (disulfiram, dsf), sodium diethyldithiocarbamate (sddc), ethylene-bis(dithiocarbamato) manganese (maneb), pyrazole (pz), aminoacetonitrile hydrogen sulfate (aan), and sodium selenite (se). all the compounds, except for se, inhibited the mutageni ... | 1979 | 228849 |
| mutagenicity of chamuvaritin: a benzyldihydrochalcone isolated from a medicinal plant. | the mutagenic effects of chamuvaritin, dihydrobenzylchalcone isolated from uvaria chamae, were investigated using salmonella typhimurium tester strains ta92, ta94--98, ta100--1535, ta1537 and ta1538. the phytochemical was mutagenic in tester strains ta98 and ta100 and required activation by the hepatic s-9 microsomal enzyme preparation. | 1979 | 228850 |
| etiology of acute gastroenteritis in children in israel: role of human reoviruslike agent and bacterial pathogens. | a study of acute gastroenteritis in children was carried out with the aim of establishing the prevalence of human reoviruslike agent (hrla) and its relation to other enteric pathogens in israel. the stools of 384 children with acute diarrhea referred to a pediatric emergency service were screened for hrla by counterimmunoelectroosmorphoresis (cieop) and for pathogenic bacteria. evidence of hrla infection was found in 65 patients (17%). the highest infection rate prevailed during the cool season ... | 1979 | 229084 |
| bacterial lipopolysaccharide depresses spontaneous, evoked, and ionophore-induced transmitter release at the neuromuscular junction. | the neurotoxocity of rna-free lipopolysaccharide (lps) extracted from salmonella typhimurium (sr-11) was tested at the frog neuromuscular junction using intracellular recording techniques. spontaneous miniature endplate potential (mepp) frequency was reduced to 45% of control after 60 minutes in the presence of 10 and 50 micrograms lps/ml ringer's solution. elevation of extracellular [ca] to 10 mm converted the mepp frequency response to a biphasic pattern of early acceleration followed by late ... | 1979 | 229236 |
| [cyclic nucleotide content in the blood and mucosa of the small intestine in salmonellosis]. | | 1979 | 229572 |
| isolation of temperature-sensitive pantothenate kinase mutants of salmonella typhimurium and mapping of the coaa gene. | temperature-sensitive pantothenate kinase mutants of salmonella typhimurium lt2 were selected by using the excretion of pantothenate at the nonpermissive temperature as a screening method. thermolability of the pathothenate kinase activity in extracts of the mutants was demonstrated. the mutations were mapped at min 89 of the salmonella chromosome, near rpob, by transduction. as pantothenate kinase catalyzes the first step in the biosynthesis of coenzyme a from pantothenate, the new genetic locu ... | 1979 | 230178 |
| [salmonellosis in children in ivory coast, (a study on 69 cases) (author's transl)]. | salmonellosis are still endemic in ivory coast. in 1975 they were responsible for 1,75 p. 100 of the admittances in the pediatric department of treichville university hospital. in children, the conventional distinction between major and minor salmonellosis is not always obvious. interpretation of widal sero-diagnosis is often difficult and awkward. chloramphenicol generally leads to satisfactory evolution. salmonellosis are still a problem for public health service. immunization, is the only eff ... | 1979 | 231722 |
| altered linkage values in phage p22--mediated transduction caused by distant deletions or insertions in donor chromosomes. | the effects of distant deletions or insertions in the salmonella typhimurium donor strains on p22--mediated cotransducibility of genetic markers was studied. we found that deletions of histidine operon, unit 44 of the chromosome map, changed the linkage of markers purf and aroc (unit 49) and pyrf and trpa (unit 34). they did not change the linkage of more distant markers pyre and cyse. the effect of three types of insertions was examined. the donor strains carried f factor, tn10 transposon or pi ... | 1979 | 232232 |
| effect of serum and blood on enterobacteriaceae grown in the presence of subminimal inhibitory concentrations of ampicillin and mecillinam. | bacteria from the strains of five species of enterobacteriaceae grown in the presence of subminimal inhibitory concentrations of ampicillin or mecillinam formed into filamentous or round cells. these filamentous and round cells as well as normal control bacteria were incubated with either fresh human serum or blood, the bactericidal effects of which were then determined. in most cases, the bactericidal effect of either serum or blood on filamentous or round cells was less than the effect on cont ... | 1979 | 232297 |
| [nonspecific prophylaxis and therapy of pseudomonas aeruginosa wound-infections with paramunization using a mouse-model (author's transl)]. | the effectiveness of paramunization as a antigen nonspecific method to activate mechanisms against wound-infections due to pseudomonas aeruginosa was studied using a model of direct infection of mice with a "mice-pathogenic" ps. aeruginosa strain on artificially set wounds. active paramunization by means of a biological inducer "pind-avi" (m-hp 438) significantly reduced the mortality rate between treated and placebo animals. the best results were obtained by parenteral prophylactic application. ... | 1979 | 232340 |
| phosphoribosylpyrophosphate (prpp) synthetase mutant in salmonella typhimurium. | | 1979 | 232626 |
| substrate-specificity of uvr excision repair. | the substrate specificity of the uvr endonuclease, the product of the uvra, uvrb, and uvrc genes is reviewed. it is suggested that the relatively well-defined substrate specificity of this repair enzyme is useful as a guide in determining the nature of the dna-lesion caused by a given mutagen. | 1979 | 233362 |
| [hygienic status of small streams on the periphery of rome. iii. research on pathogenic microorganisms]. | | 1979 | 233380 |
| [epidemiology of r plasmid and transferable antibiotic-resistance (author's transl)]. | the aa. review the basic characteristics of extra-chromosomal antibiotic-resistance along with research guide-lines concerning the epidemiology of r plasmids. they then report the results of their investigations on isolated salmonellae during the years 1971-1977. while s. typhimurium and s. wien showed an high incidence of transferable antibiotic-resistance, other salmonellae belonging to 32 different serotypes had low incidence rates. | 1979 | 233477 |
| isolation of super-repressor mutants in the histidine utilization system of salmonella typhimurium. | two super-repressor mutations in the histidine utilization (hut) operons of salmonella typhimurium are described. cells bearing either of these mutations have levels of hut enzymes that do not increase above the uninduced levels when growth is in the presence of either histidine or the gratuitous inducer imidazole propionate. both mutations lie in the region of the gene for the hut repressor, hutc, and reverse mutations of both are to the constitutive (repressor-negative) rather than to the indu ... | 1975 | 234417 |
| deoxycytidine triphosphate deaminase of salmonella typhimurium. purification and characterization. | deoxycytidine triphosphate deaminase (ec 3.5.4., dctp aminohydrolase) of salmonella typhimurium lt2 has been pruified 500-fold. the reaction requires the presence of mg-2plus, mn-2plus, ca-2lus, or co-2plus. kinetics of the reaction with varying mg-2plus concentrations, keeping the concentration of dctp constant, suggests that the true substrate of the reaction is mgdctp. the dependence of the rate of reaction on dctp concentration in the presnece of 5-fold excess of mg-2plus is sigmoid, with a ... | 1975 | 234434 |
| peyer's patch responsiveness to salmonella in mice. | | 1975 | 234533 |
| [changes in the antibacterial effects of organs and tissues of ornithodoros papillipes birula ticks]. | | 1975 | 234572 |
| use of ph gradient plates for increasing the acid tolerance of salmonellae. | several strains of salmonellae survived higher concentrations of lactic acid after streaking on the surface of ph gradient plates. most strains increased their acid tolerance by about 0.8 to 1.0 ph unit (9-to 10-fold), with salmonella madelia showing the greatest differential, ph 5.2 in the wild strain and ph 4.2 after conditioning. the increased acid resistance was quickly lost after transferring to normal tryptic soy agar. tests for survival in a liquid medium at ph values lower than those giv ... | 1975 | 234717 |
| volume, adherence properties, membrane antigens and mitogen responsiveness of rabbit lymphoid cell subpopulations. | subpopulations of rabbit spleen cells which respond to t and b mitogens, respectively, can be distinguished by sedimentation velocity in the earth's gravitational field. t cell subpopulations which differed in their responsiveness to con a and to pha could be identified by differences in adherence properties and by their sensitivity to complement mediated cell kill with rtla-antiserum. | 1975 | 234909 |
| assay, characterization, and localization of an enterotoxin produced by salmonella. | an enterotoxic factor isolated from cultures of salmonella yielded reproducible results in the suckling mouse model in contrast to other animal models. the enterotoxin appears to possess properties similar to both the heat-stable and heat-labile enterotoxins of escherichia coli. preliminary results indicate that the toxin is a protein, is located in the cell wall or outer-membrane fraction, and is difficult to separate from other cell wall constituents. | 1975 | 234910 |
| phagocytosis of francisella tularensis by rhesus monkey peripheral leukocytes. | phagocytosis of francisella tularensis by rhesus monkey peripheral neutrophils (pmn, was assessed by autoradiography, electron microscopy, and biochemical techniques. pmn, in contrast to mononuclear phagocytes, were unable to phagocytize f. tularensis in vitro in the absence of immune serum. it is postulated that in the nonimmune host the innate inability of pmn to phagocytize f. tularensis deletes one of the possible mechanisms of host defense to bacterial infection and thus permits the early d ... | 1975 | 234911 |
| liver glutathione and glutathione reductase response of endotoxin-treated mice. | the decrease in the level of liver glutathione (gsh) in endotoxin-treated mice was in part due to formation of glutathione disulfide (gssg). an electron-generating system (egs) had no effect when incubated with soluble liver extracts from normal controls but resulted in recovery of gsh amounting to 25% in endotoxin-treated animals. incubation in the absence of the egs caused a decline of 16% in the gsh in extracts from normal animals compared with a 50% decrease in endotoxin-treated animals. exc ... | 1975 | 234913 |
| [resistance to antibiotics, furan drugs and sulfathiazole of s. typhi and s. paratyphi b strains isolated from patients and carriers in the years 1957-1973]. | | 1975 | 235056 |
| microsomal activation to mutagens of antischistosomal methyl thioxanthenones and initial tests on a possibly non-mutagenic analogue. | five methylthioxanthenone and methylbenzothiopyranoindazole analogues, including lucanthone (miracil d), are non-mutagenic for salmonella typhimurium but are activated to mutagens by a rat liver microsome preparation. hydroxymethyl analogues, including hycathone (etrenol), are mutagenic in the absence of microsomes. it seems reasonable to assume that the hydroxymethyl derivatives are the more proximal mutagens and that salmonella is unable to carry out the hydroxylation necessary for mutagen act ... | 1975 | 235087 |
| differential fluorescence labelling with 5-dimethyl-aminonaphthalene-1-sulfonyl chloride of intact cells and isolated membranes in salmonella typhimurium and acholeplasma laidlawii. | for fluorescence labelling intact cells and isolated cell envelopes (membranes) from salmonella typhimurium and acholeplasma laidlawii were treated with mixed dansylchloride-lecithin-cholesterol vesicles. this kind of dansylation, which has been supposed to be specific for cell surface proteins, produced fluorescent protein pattern after sds-polyacrylamide gel electrophoresis only when isolated envelopes were dansylated. acid hydrolysis of fluorescent cell envelopes of salmonella typhimurium yie ... | 1975 | 235245 |
| 1-alkyl-2-nitroimidazol-5-yl derivatives. i. | | 1975 | 235267 |
| genetics of chemotactic behavior in bacteria. | | 1975 | 235371 |
| purine nucleoside phosphorylase from escherichia coli and salmonella typhimurium. purification and some properties. | the purine nucleoside phosphorylases from escherichia coli and from salmonella typhimurium have been purified to electrophoretic homogeneity and crystallized. comparative studies revealed that the two enzymes are very much alike. they obey simple michaelis-menten kinetics for their substrates with the exception of phosphate for which they show negative cooperativity. gel filtration on sephadex g-200 of the native enzymes revealed a molecular weight for both enzymes of 138000 plus or minus 10%. b ... | 1975 | 235429 |
| the compu-pet 100: a versatile dispenser-diluter for the mechanization of microbiological techniques. | the compu-pet 100 diluter/dispenser is a versatile and accurate instrument which can be employed for a wide variety of microbiological tests and techniques. time in performing tests is often more than halved when the diluter is used. large numbers of tests can be performed with minimal fatigue. | 1975 | 235570 |