| phospholipase d activity of gram-negative bacteria. | a phospholipase hydrolyzing cardiolipin to phosphatidic acid and phosphatidyl glycerol was characterized in gram-negative bacteria but was absent in preparations of gram-positive bacteria, saccharomyces cerevisiae, and rat liver mitochondria. in cell-free extracts of escherichia coli, salmonella typhimurium, proteus vulgaris, and pseudomonase aeruginosa, this cardiolipin-hydrolyzing enzyme had similar ph and mg2+ requirements and displayed a specificity which excluded phosphatidyl glycerol and p ... | 1975 | 360 |
| profiles for ph, temperature, and dissolved o2 levels in enzyme production: monitoring in small-scale fermentors. | the profiles thus established may be utilized for investigations of an organism's relationship to its microenvironment including metabolic shifts and pathways. areas of maximum respiratory activity, enzyme production, enzyme degradation, and attainment of the stationary phase are quite evident; however, duration and magnitude of the various phenomena may change with nutrient, temperature, and aeration efficiency. practical application of this simplified method would include: a) determination of ... | 1975 | 1123 |
| isolation and characterization of crystalline methylglyoxal synthetase from proteus vulgaris. | methylglyoxal synthetase, which catalyzes the conversion of dihydroxyacetone phosphate to methylglyoxal and inorganic phosphate, has been isolated and crystalized in good yields from proteus vulgaris. the enzyme was shown to be homogeneous by a variety of criteria and was found to be a dimer (mr = 135,000; s20,w = 7.2 s) composed of two apparently identical catalytic and physical properties and their interconvertible nature suggest that they do not represent true isozymes. the enzyme is specific ... | 1976 | 1386 |
| microbiological study of gentamiycin. | gentamycin prepared at the all-union research institute of antibiotics did not differ by its antibacterial spectrum and the activity level from gentamycin samples from other countries. by its activity against clinical strains of ps. aeruginosa gentamycin was somewhat inferior than polymyxin but much more superior than carbenicillin. an agar-diffusion method using bac. pumilus ntcc 8241 as the test microbe was developed for determination of gentamycin activity. the gentamycin sulfate complex and ... | 1975 | 2095 |
| approach to a practical method for screening and identifying microorganism genera from urine (author's transl). | in this study the author reported upon a practical new system for screening and identifying the microbial agents causing urinary tract infections. this system is composed of a combination of 3 screening procedures (ph-value + nitrite-test + catalase-test) and 8 selective culture media for the purpose of genus identification within 24 hours (uripret-g). a total of 130 cultures was investigated. the employed microorganisms were mainly recovered from urine samples. they included the following speci ... | 1976 | 11179 |
| purification and properties of aldehyde dehydrogenase from proteus vulgaris. | nadp-linked aldehyde dehydrogenase (aldehyde : nadp+ oxidoreductase, ec 1.2.1.4) was purified from proteus vulgaris to the stage of homogeneity as judged by ultracentrifugation and polyacrylamide gel electrophoresis. the molecular weight of the purified enzyme was estimated to be 130000 by gel filtration. the enzyme which was crystallized from ammonium sulfate solution, lost its activity. the enzyme did not require coenzyme a, and the reaction was completely dependent on ammonium ions which coul ... | 1977 | 13839 |
| intracellular nucleodepolymerase of bacteria, representatives of the proteus and providencia groups. its isolation and properties. | high activity of enzymes, splitting native, denaturated dna, deoxyribooligonucleotides and rna, was observed in cell free extracts of bacteria--representatives of 5 strains of proteus-providencia. some properties of nucleases were studied in cell free extracts. in the bacteria studied dnaases were thermolabile proteins, which were completely inactivated at 50-60 degrees, rnaases were more thermostable. the ph optima of the dnaases were at ph 9.0-11.0 in cell free system; rnaases were maximally a ... | 1976 | 17219 |
| inhibition of bacterial agmatinase by substrate analogs. | activity of agmatinase (ec 3.5.3.11) from proteus vulgaris was studied in presence of guanidine derivatives of agmatine as substrates. the guanidine derivatives, containing carboxyl group, did not interact with the enzyme. an inhibitory effect developed if the carboxyl group was esterified. for exhibition of the effect the length of hydrocarbon radical in ligand and presence of hydrophobic groups were important. one of the most effective inhibitor was n-isoamylene agmatine (k1=0.001 m). compound ... | 1976 | 17224 |
| phosphonic analogues as antagonists of amino acid excitants. | | 1977 | 17707 |
| identification of essential histidine residues of aminoacylase by photooxidation and by reaction with diethylpyrocarbonate. | state and function of the histidine residues of aminoacylase were investigated by photoxidation in the presence of methylene blue and by chemical modification with diethylpyrocarbonate. complete inactivation of the enzyme was observed after oxidation of 4 histidine residues. from the ph dependence of the photooxidation it becomes evident that the inactivation of the enzyme is not a consequence of the simultaneous oxidation of tryptophan residues. the enzyme is also inactivated by chemical modifi ... | 1977 | 17959 |
| contamination of rat urine with gut flora using all-glass metabolism cages for collection of urine and faeces. | in rat urine collected in all-glass metabolism cages, at least four strains of intestinal microflora were found: two types of e. coli, enterobacter cloaceae and proteus vulgaris. the number of bacteria of each strain increased with time. 2. the ph of the urine increased from 6-9 after 24 h to 8-95 after 120 h. the ph of the urine of neomycin-treated rats remained nearly constant over a period of two days. 3. nitroreductase activity was present in the rat urine. added p-nitrobenzoic acid was redu ... | 1977 | 18846 |
| tissue fractionation in neurobiochemistry: an analytical tool or a source of artifacts. | | 1977 | 22511 |
| intradermal responses to common bacterial antigens: influences of sex and clinical condition. | intradermal responses to antigens of 12 common bacteria were evaluated in 218 dermatologic and 155 respiratory patients. women responded more frequently than men and respiratory patients responded significantly more frequently than dermatologic patients to certain antigens. interpretation of interspecies associations of responses suggested that certain organisms may be key species in the development of bacterial hypersensitivity. | 1979 | 37788 |
| interaction of complex polysaccharides with the complement system: effect of calcium depletion on terminal component consumption. | complex polysaccharides and lipopolysaccharides can activate the terminal components of complement by either the classical (antibody, c1, c4, and c2) or alternative complement pathways, but the relative importance of either pathway for terminal component consumption in normal serum is poorly understood. since classical complement pathway function requires both calcium and magnesium ions, whereas the alternative pathway requires only magnesium ions, selective chelation of calcium ions in serum ca ... | 1975 | 46215 |
| esterase zymograms of proteus and providencia. | the intracellular esterases of 80 strains of proteus and providencia were analysed by the acrylamide-agarose zymogram technique using several synthetic substrates. the esterase bands were classified in five main groups. the alphaa-esterase bands hydrolysed alpha-naphthyl acetate and were resistant or relatively insensitive to di-isofluoropropyl phosphate (dfp). the alphab-esterase band hydrolysed both alpha-naphthyl acetate and alpha-naphthyl butyrate and were very sensitive to dfp. both groups ... | 1975 | 48538 |
| studies on lipopolysaccharides of proteus vulgaris serogroups. chemotypes of genus proteus lipopolysaccharides. | | 1975 | 55287 |
| [the effect of ear surgery to the immunologic defense system of the middle ear during chronic otitis media (author's transl)]. | alpha-1-antitrypsin and alpha-2-macroglobuline are very important proteinase inhibitors for the healing process in chronic otitis media, because they can inhibit numerous bacterial and leukocytic proteinases: alpha-2-macroglobuline can block the malignant proteinases of pseudomonas aeruginosa, staphylococcus aureus and proteus vulgaris. in 58 cases in the middle ear secretion was examined and the level of alpha-1-antitrypsin and alpha-2-macroglobulin investigated pre- and postoperatively. by the ... | 1976 | 63098 |
| specific and cross-reactive activation of rabbit peripheral blood lymphocytes by streptococcal vaccines. | the ability of primed rabbit blood lymphocytes to respond in vitro to the homologous streptococcal group antigen depends on its presence in culture in the form of vaccine or cell walls thereof. these lymphocytes can also be stimulated in vitro by streptococcal vaccines with chemically related group antigens. the basis for this cross-stimulation apparently resides in shared rhamnose moieties. activation of these lymphocytes was not achieved by vaccines from unrelated bacteria. there is also the s ... | 1978 | 74347 |
| study of the glycolipid composition of the milk fat-globule membrane and the mouse mammary tumour virus prepared from the milk of infected swiss mice [proceedings]. | | 1978 | 84579 |
| the spinal cord protein (scp): appraisal of physiological and immunological hypotheses of anti-encephalitogenic action. | | 1978 | 85602 |
| in vitro synthesis of infectious transforming dna by the avian sarcoma virus reverse transcriptase. | infectious dna molecules, capable of transforming chicken embryo fibroblasts, can be synthesized by the rous sarcoma virus-associated reverse transcriptase in vitro. the optimal enzymatic conditions employed for infectious dna synthesis also facilitate maximum synthesis of genome length dna. analysis of the dna product synthesized by detergent-disrupted rous sarcoma virus under these conditions indicates that dna complementary to viral rna (minus-strand dna) is genome length in size, whereas dna ... | 1979 | 85719 |
| the use of trypan blue for counterstaining in the sepharose bead immunofluorescence test. the application of the test for the demonstration of primate retrovirus-specific antibodies and antigens. | the sepharose bead immunoflurorescence test was performed by counterstaining the beads with trypan blue. this results in a red staining of negative beads which allows an easy distinction from positive green-fluorescent beads. sepharose beads conjugated with viral proteins or antiviral antibodies were used to demonstrate mason-pfizer monkey virus (mpmw)- and simian sarcoma virus (ssv) - specific antigens or antibodies. the test shows a high sensitivity and specificity and needs a small amount of ... | 1978 | 86253 |
| definition of two ld antigens in rhesus monkeys. | two rhesus (macaca mulatta) monkey lymphocyte-defined (ld) antigens have been identified using two typing cells as stiumlators in a one-way mixed leukocyte culture (mlc) assay. an analysis of the genetic behavior of these ld antigens in six rhesus monkey families revealed that both antigens were linked with rhla. one probable recombinant indicated that the ld locus lies outside the two known rhla-sd loci and the locus which controls the serum protein, properdin b(bf). these two antigens, ld1 and ... | 1979 | 87026 |
| similarity of casein- and endotoxin-induced, myeloma- associated and aged sjl/j amyloid in various strains of mice. | amyloidosis was induced in a number of strains of mice by repeated injections of casein and endotoxin. spontaneous amyloid was obtained from balb/c mice bearing a myeloma tumor (igg2a producing mopc 173 tumor) and from aged sjl/j mice. both the induced and spontaneous forms were similar in their size, immunological reactivity, peptide maps and in the susceptibility of histological sections to oxidizing agents with or without trypsin digestion. since case-induced murine amyloid resembles the noni ... | 1979 | 87374 |
| moloney virus-induced cell surface antigens and histocompatibility antigens are located on distinct molecules. | | 1979 | 87439 |
| pattern of milk flow in breast-fed infants. | 122 six-day-old infants were test-weighed during breast feeding. cross-sectional data collection avoided repeated interruptions of individual feeds. milk flow conformed to a definite pattern: a mean of 50% of the feed from each breast was taken in the first two minutes of sucking and a mean of 80-90% was taken by four minutes. the second half of a ten-minute feed from either breast was almost non-nutritive. preliminary studies suggest that the pattern is the same after one month of lactation. | 1979 | 87962 |
| denaturization of allergen p: effect on allergenicity, antigenicity and immunogenicity. | when allergen p was denatured by 8m urea, the modified molecule still reacted with ige specific for the native allergen but not with hemagglutinating antibodies. heating at 100 degrees c abolished the reaction in both cases. the results suggested differences between allergenic and antigenic capacities which may be based on structural differences of the antigenic determinants. | 1979 | 88195 |
| the role of p23,30-bearing human macrophages in antigen-induced t lymphocyte responses. | | 1979 | 88270 |
| a new assay of estrogen receptor by thin-layer gel filtration. | | 1979 | 88911 |
| [post-extrasystolic and post-pacing potentiation. i. experimental study of the isolated heart of the rabbit]. | | 1978 | 88947 |
| reaction of cells from early chick embryos with antiserum against mouse sperm cells. | | 1979 | 89009 |
| preparative isolation of the cell receptor for immunoglobulin e. | | 1979 | 89114 |
| cimetidine: interaction with oral anticoagulants in man. | in 6 patients anticoagulated with warfarin, nicoumalone, or phenindione the addition of cimetidine prolonged the prothrombin-time (pt) by a mean of 12.6 s (range 5--23 s). in 7 volunteers taking daily subtherapeutic doses of warfarin the addition of cimetidine increased the pt from 19.4 to 22.9 s and the plasma-warfarin concentration from 0.96 to 1.76 microgram/ml. cimetidine reduced the single-dose clearance of warfarin and antipyrine. the basis of the interaction between cimetidine and oral an ... | 1979 | 89387 |
| [studies on human immunoglobulin preparations: i. viral antibody profiles (author's transl)]. | a study was undertaken to assess the viral antibody spectrum in human immunoglobulin preparations from four different manufacturers for intravenous and/or intramuscular application. studies of the kind seem to be reasonable for calculating the expected therapeutic effect of the administered immunoglobulin. the investigated 16 gammaglobulin batches showed almost the same variety of viral antibodies and only slightly differring antibody titers. it is interesting to note, that antibodies to vaccini ... | 1979 | 89620 |
| regulation of collagenase. therapeutic considerations. | why the cornea ulcerates, in the sense of what goes awry, may be related to the trapping of wound healing in a phase of proteolytic debridement related to a persistent epithelial defect. the initial avascularity of the cornea makes it particularly vulnerable to proteolytic damage. studies on the biochemistry and cell biology of corneal ulceration have indicated that sequential interactions occur which result in the generation of collagenase activity and the development of ulceration. it is likel ... | 1978 | 89726 |
| monkey antiserum to mlc-primed human t lymphocytes. | | 1979 | 89737 |
| steroid secretion by in vitro perfused testes: inhibitors of testosterone biosynthesis. | | 1979 | 89816 |
| antibodies in histoplasmosis detected by use of yeast and mycelial antigens in immunodiffusion and electroimmunodiffusion. | | 1979 | 89825 |
| alpha-fetoprotein as a carrier protein in plasma and its bilirubin-binding ability. | the bilirubin-binding ability of human alpha-fetoproteins, which were purified from fetal cord serum and from ascites fluid of a hepatoma-bearing patient, was examined by the difference spectrum and the jacobsen peroxidase methods. the difference spectrum observed as a result of the specific binding of bilirubin to alpha-fetoprotein had a maximum at 482 nm, and this pattern was quite similar to that observed for serum albumin. the result obtained by the difference spectrum method showed that 1 m ... | 1979 | 89900 |
| [a further case of tn-polyagglutination]. | another case of tn-polyagglutination is described where for 6 years those responses have been observed which are typical of the acquired erythrocyte changes, viz. mixed-field polyagglutination by normal adult sera of all blood groups, no response with anti-tah, agglutination of a certain part of erythrocytes by anti-tnss, anti-adb, anti-ahp, agglomeration of the other part by protamin sulfate and a-like specificity. papain treatment eliminates polyagglutination by human sera of adults. sera of n ... | 1979 | 89994 |
| in vitro studies of the replication of moloney murine leukemia virus. | | 1979 | 90575 |
| the effect of bleomycin on rat bone marrow cells. | experiments were carried out to determine the cytogenetic effects of the antibiotic bleomycin (blm) in rats using the bone marrow system. a total of eighteen male and eighteen female sprague-dawley rats were injected with varying concentration of blm, over varying periods of time. the results revealed that at low concentrations blm showed no alteration in the ploidy or the morphology of rat chromosomes. this however, was not the case when the dose or administration period was increased. | 1978 | 90585 |
| relative affinity of antisera for myelin basic protein (mbp) and degree of affinity heterogeneity. | | 1979 | 90641 |
| the location and expression of idiotypic determinants in the immunoglobulin variable region--i. characterization of antibodies directed against the variable region of mouse myeloma immunoglobulins 315 and 460. | | 1979 | 90644 |
| purification of a new high activity form of glucose-6-phosphate dehydrogenase from rat liver and the effect of enzyme inactivation on its immunochemical reactivity. | a new form of cytoplasmic glucose-6-phosphate dehydrogenase (e.c.1.1.1.49) was purified from rat liver by protamine sulfate precipitation, ammonium sulfate fractionation, ion exchange chromatography with diethylaminoethyl cellulose, and affinity chromatography with cibacron blue agarose and nadp agarose. this form of the enzyme has a specific activity of over 600 units/mg of protein and gives essentially a single band by polyacrylamide gel electrophoresis. the form of the enzyme isolated by this ... | 1979 | 90677 |
| [the effect of cerebral perfusion pressure in cerebral infarction after occlusion of middle cerebral artery in dog (author's transl)]. | | 1979 | 91991 |
| viability assessment by dye exclusion. a fluorescent method for fungal cells. | a new fluorescent staining technique for fungi utilizes the differential affinity of dead cells for rhodamine b. a mounting medium has been devised that includes the dye. this medium allows direct processing of cells from a broth and provides optimal conditions for fluorescence intensity. comparison with the standard methylene blue exclusion test as applied to the candida albicans yeast phase indicates similar specificity. various pseudohyphae and several fungi also exhibited selective uptake of ... | 1979 | 92216 |
| populational polymorphisms in silver staining of nucleolus organizer regions (nors) in human acrocentric chromosomes. | the ag stainability of the nucleolus organizer region (nor) was studied in the acrocentric chromosomes identified by q banding of cultured lymphocytes in 41 karyotypically normal persons (33 males and 8 females) originating from southeast estonia. the data obtained are compared with those established earlier for a combined vienna-ulm population of 51 karyotypically normal persons (see mikelsaar et al., 1977a). significant differences between the two populations in the frequency and patterns of a ... | 1979 | 92452 |
| nonspecific light loss and intrinsic dna variation problems associated with feulgen dna cytophotometry. | nonspecific light loss by the cell-wall-plus-cytoplasm (cwc) can cause a 50% increase in feulgen absorption units in peanut root-tip nuclei as determined by scanning at 450 nm, whereas this phenomenon is not evident with chicken erythrocytes. a two wavelength scanning method of subtracting nonspecific 450 nm absorption from 550 nm feulgen absorption values eliminated the nonspecific light loss in cwc, however, the two wavelength scanning method is time consuming and somewhat impractical with a r ... | 1979 | 92496 |
| the carbohydrate content of apolipoprotein e from human very low density lipoproteins. | | 1979 | 92742 |
| enhancement of retrovirus production by anti-interferon serum. | in order to investigate the role of endogenous interferon in retrovirus production by infected or induced cells, the effect of two sera raised against mouse interferon has been tested on various c-type murine viruses. addition of a highly potent anti-interferon serum to 3t3/ic cells chronically infected by the moloney strain of mlv results in a considerable increase of virus production, as tested by reverse transcriptase assay. this effect is neutralized by an excess of exogenous interferon. the ... | 1979 | 93859 |
| a model study for determining the mechanism of exposure of leukemia-specific antigen on dinitrophenylated leukocytes. | | 1979 | 94299 |
| immunodiagnosis of systemic candidiasis: mannan antigenemia detected by radioimmunoassay in experimental and human infections. | a radioimmunoassay (ria) that detects candida mannan was developed so that immunodiagnosis of systemic candidiasis could be improved. the ria was evaluated in an animal model of disseminated disease and in a panel of patient sera. mannan antigenemia was detected with the ria in 52% of 29 rabbits with systemic candidasis, but not in 60 normal rabbits or 31 rabbits with systemic aspergillosis. in an evaluation of human sera, mannan antigenemia was detected in five of 11 patients with systemic cand ... | 1979 | 94341 |
| comparison of the antibodies elicited by the individual structural polypeptides of foot-and mouth disease and polio viruses. | antibody produced against preparations of vp1, one of the four structural polypeptides of foot-and-mouth disease virus, neutralized the virus and reacted with both full and empty particles in radioimmunoassays (ria). antiserum against vp2 reacted with artificial empty particles of the virus but not with full particles. in contrast, none of the individual polypeptides of poliovirus produced antisera which neutralized the virus nor reacted with it in ria. however, antisera produced with vp1 and vp ... | 1979 | 94352 |
| thyroid hormone regulation of alpha-adrenergic receptors: studies in rat myocardium. | the effects of alterations in thyroid state on cardiac alpha-adrenergic receptors were investigated by the binding of [3h]dihydroergocryptine (dhe), a potent alpha-adrenergic antagonist. in seven experiments, cardiac membranes from euthyroid rats bound 47 +/- 9 fmoles dhe/mg protein (mean +/- se) at saturation and demonstrated a dissociation constant (kd) of 2.5 +/- 0.4 nm. hyperthyroidism, produced by parenteral injection of triiodothyronine, significantly reduced the binding of dhe at all conc ... | 1979 | 94388 |
| cellular and virological studies directed to the pathogenesis of the human myelogenous leukemias. | 1. work over the past years and especially results of the past few years indicate that type-c viral or viral related genetic information exists in humans. 2. we do not know how this information entered humans or whether it causes disease, but it is of interest that the probes from the viruses used to detect this information are from the very same viruses which we find can affect growth and differentiation of some human hematopoietic cells. 3. the status of actual virus isolates from humans, thou ... | 1979 | 94583 |
| observations of vitamin e in experimental oxygen-induced retinopathy. | retrolental fibroplasia (rlf) is a proliferative retinopathy observed in premature infants. its relationship to oxygen has led to both clinical and laboratory research into the potential benefits of the antioxidant tocopherol in this disorder. although the clinical trials to date have only suggested a beneficial result, studies in the kitten model demonstrate two significant actions of tocopherol in protecting against this retinopathy, only one of which is predicted by theory. these data support ... | 1979 | 95420 |
| development of visual acuity in infant monkeys (macaca nemestrina) during the early postnatal weeks. | | 1978 | 96592 |
| chymotrypsinlike activity of some intestinal bacteria. | some tests of exocrine pancreatic function are based on the estimation of intestinal chymotryptic activity by using specific substrates such as n-benzoyl-l-tyrosyl-paba (bt-p). in this study the action of a number of bacteria isolated from human or monkey intestines on bt-p was investigated. the monkeys studied had an intestinal flora closely resembling that of man. except for bacteroides, proteus vulgaris no. 73, proteus morgani no. 202, and pseudomonas aeruginosa no. 76, significant splitting ... | 1978 | 98039 |
| [some aspects relating to the aflatoxin generation during the self-heating of cereals]. | in a stored batch of grain which was already affected by mould-formation tests were carried out with the known aflatoxin producer aspergillus flavus. a significantly lower aflatoxin production ensued if the mould growth was not connected with self-heating of the stored product. however, in conformity with increasing mould formation the germinating power was adversely affected and the significant signs (fatty acid number, reductive and none-reductive sugars) were influenced in the grain, irreleve ... | 1978 | 98933 |
| age-associated changes in the blood picture of the goat. | | 1978 | 98936 |
| behavioral measurement measurements of excitability changes in reward sites in the dog: a frequency dependent effect. | | 1978 | 99757 |
| [studies on moraxella. i. a new selective medium for moraxella sp. (author's transl)]. | | 1977 | 101603 |
| [epidemiological study on beta hemolytic streptococci among healthy school children in toda city, saitama (author's transl)]. | | 1978 | 101618 |
| [microbiological characteristics of intestinal dysbacteriosis in acute leukemia]. | | 1978 | 101983 |
| effects of combinations of phencyclidine and pentobarbital on schedule-controlled behavior in the squirrel monkey. | three squirrel monkeys trained on a variable interval schedule of food presentation were used to examine the interaction between phencyclidine (pcp) and pentobarbital (pb). first, dose-response curves for each drug given alone were obtained. pcp caused small response rate increases at low doses, and a dose-dependent decrease in responding at higher doses. pb caused only dose-dependent decreases in responding. the pb dose-response curve was then redetermined in the presence of four doses of pcp. ... | 1978 | 101988 |
| dietary lactose and the aetiology of human small-intestinal hypolactasia. | | 1978 | 103781 |
| blood-brain barrier opening by isotonic saline infusion in normotensive and hypertensive animals. | the blood-brain barrier to intravascular evans blue-albumin was opened in monkeys and rabbits by infusing isotonic saline for 15 s into the common carotid artery, when the external carotid was clamped temporarily and the lingual was catheterized for measuring pressure. barrier opening correlated better with infusion pressure than with infusion rate, and occurred at carotid artery pressures above 170 mmhg. systemic hypertension induced by aramine increased barrier vulnerability by causing a highe ... | 1978 | 104549 |
| [isolation of treponemas from the colon of pigs with clinical dysentery]. | optimal culture conditions in artificial nutritive media were determined for a defined avirulent strain of treponema hyodysenteriae and for four field strains of treponemas in pigs with clinical dysentery. the treponemas were isolated with the use of milliporous filters with pores of 0.3 micrometer in diameter, which were located on the surface of blood agar. no significant difference in the influence of equine, bovine or sheep blood on the growth of treponemas was determined. the commercial amo ... | 1979 | 105448 |
| [b. cereus count in meat and dairy food products]. | studies were carried out to establish the contamination of some meat and dairy food products with b. cereus. a total of 48 heat-treated sausages (32 perishable and 16 durable) and 64 batches of pasteurized milk were sampled. it was found that 25 per cent of investigated sausage samples contained b. cereus. perishables proved to a considerable extent more frequently contaminated (33.3 per cent). the count of b. cereus in such products ranged from 10(1) to 10(3) per g. however, pasteurized milk wa ... | 1978 | 105462 |
| [changes in the spectrum of disease-causing bacteria]. | | 1978 | 105494 |
| [lysozyme concentration in the loose connective tissue of animals with different species sensitivity to brucellosis]. | lysozyme content was determined in the subcutaneous cellular tissue of guinea pigs and albino rats differing by species resistance to brucella infection. experiments were conducted on intact animals and those inoculated subcutaneously with live br. abortus 19-ba vaccine. connective tissue was taken from the site of the vaccine administration and from the contralateral side (control). observations showed connective tissue of the animals highly sensitive to brucella infection to be exceedingly poo ... | 1978 | 105522 |
| further observations on the initiation of sperm motility. | | 1978 | 105770 |
| restricted posterior parietal lesions in the rhesus monkey and performance on visuospatial tasks. | monkeys with lesions restricted to the inferior parietal lobule or the banks and depths of the superior temporal sulcus were tested on a route-following task. these areas are considered on neuroanatomical grounds to be homologous to parts of the human posterior parietal cortex, where lesions produce profound spatial disorientation. the operated monkeys were impaired on the route task, thus confirming at the behavioural level the anatomical predictions of comparability between parietal cortex in ... | 1979 | 103604 |
| new antibiotics, enaminomycins a, b and c. ii. physico-chemical and biological properties. | physico-chemical characterization of enaminomycins revealed that these antibiotics are new members of the epoxy quinone family. from elementary analysis and mass spectroscopic measurements the molecular formulae of enaminomycins a, b and c appear to be c7h5no5, c10h11n06 and c7h7no5, respectively. they are very unique in their chemical properties, possessing various functions, such as epoxy, primary amine and carboxylic acid, in their small structural units. enaminomycin a, the most potent compo ... | 1978 | 101500 |
| insulin and glucagon binding and degradation by kidney cell membranes. | the binding and degradation of insulin and glucagon to kidney cell membranes was examined. time- and temperature-dependent specific binding of [125i]iodo-insulin to kidney cell membranes was demonstrated. the membranes also degraded insulin in a time-, temperature-, and protein concentration-dependent manner. the apparent km of the degradation was 2.7 x 10(-7) m. glucagon degradation by the kidney membranes was extremely active. per milligram of protein the kidney membrane was over 20 times as a ... | 1978 | 105882 |
| thyrotropin response to thyrotropin-releasing hormone in the euthyroid rat: dose-response, time course, and demonstration of partial refractoriness to a second dose of thyrotropin-releasing hormone. | | 1978 | 105883 |
| [intracellular distribution of two lysosomal enzymes in newborn rat liver]. | the distribution of two lysosomal markers (beta-acetylglucosaminidase and acid phosphatase) between liver fractions was studied in the newborn rat. the results indicate that after birth the hydrolase-bearing particles increased in size and had a lower density than the primary lysosomes. these modifications may be related to the autophagic-vacuole formation known to occur during this period. | 1978 | 96999 |
| [concentration of testosterone and luteinizing hormone in the blood plasma of steers during the first year of life]. | | 1978 | 106582 |
| [immunological problems in oncology (author's transl)]. | the authors, after a view of the problems of immunology, regarding the most recent discoveries, deal with the conclusions about the immunological reactions in research and clinical oncology. many specific antibodies, formed as a result of the tumor, have been discovered in the field of research. it is impossible to say the same about human tumors and the probable hypothesis are numerous. the results until now obtained, even if they don't give a definite response, show that the immune defense of ... | 1979 | 95475 |
| transducing activity of bacteriophage spp1. | | 1979 | 106856 |
| demonstration of a murine cell surface component with affinity for exogenous beta 2-microglobulin. | murine and human beta 2-microglobulin (beta 2m) bind to various types of mouse cells. the binding is saturable and displays a single association constant of about 1 x 10(9) liter/mol. the binding of beta 2m to splenocytes was not affected by a variety of metabolic inhibitors but was temperature-dependent. it is suggested that the beta 2m "receptor" exhibits a temperature-dependent conformational change since the "receptor", whether integrated into the membrane or solubilized by the detergent tri ... | 1979 | 95108 |
| studies on fibronectin in the skin. iii. indirect immunofluorescence studies in lichen planus. | fibronectin is a glycoprotein which is responsible for a varity of functions in the human organism, such as mediation of contact between cells and between cells and fibres, opsonic qualities, interaction in the stabilization of fibrin, etc. fibronectin is an important constituent of the ground substance having a special affinity to collagen. in indirect immunofluorescence studies its presence has been abundantly demonstrated in normal human skin, in collagen-rich structures such as the basement ... | 1979 | 94206 |
| isolation of listeria monocytogenes from animals in the sudan. | | 1979 | 107996 |
| decadent sporulation mutants of bacillus subtilis. | in decadent sporulation mutants, sporulating populations are heterogeneous: the cells reach successive chemical and physical resistances with progressively decreasing frequencies. each decadent mutant can be characterized by the shape and slope of the curve describing the frequency of cells resistant to various agents ('the resistance spectrum'). in some mutants the resistance spectrum decreases progressively from xylene resistance to heat resistance; in other mutants it decreases rapidly betwee ... | 1979 | 108358 |
| [microorganisms of genus haemophilus, their biological and serological characteristics (literature review)]. | | 1979 | 92600 |
| a new principle of injectable depot contraceptives. i drug selection and studies in monkeys. | the aim of the investigations was to develop a long-acting depot contraceptive on the basis of norethisterone or levonorgestrel. disappointing results with levonorgestrel nonanoate and levonorgestrel undecylate showed that elongation of the fatty acid, esterified with the steroid, decreased the bioavailability of the latter due to incomplete hydrolysis of the ester. therefore, several new compounds were synthesized which contained a bifunctional molecule between the steroid and the fatty acid. i ... | 1979 | 110513 |
| the role of eosinophil receptors in the non-genomic response to oestrogens in the uterus. | | 1979 | 90751 |
| coupling between neuronal activity and focal blood flow in experimental seizures. | local blood flow, ecog and single cortical neurone activity were recorded simultaneously from single microelectrodes in 17 cats. seizures were induced by repeated intravenous injections of pentylenetetrazol (ptz, 10-20 mg/kg) or by local application of 1 m na-penicillin. seven to 20 sec after appearance of burst activity in cortical neurones and ecog, focal flow increased up to 300% of control. the extent of this flow increase was significantly correlated with the change in firing rate of the ne ... | 1979 | 89943 |
| structure of the gene n:gene ns intercistronic junction in the genome of vesicular stomatitis virus. | | 1979 | 89911 |
| in vitro response to rosette inhibition factor (rif) and rosette restoring factor (rrf) of human lymphocyte after fractionation on a discontinuous density albumin gradient. | in vitro studies on peripheral blood lymphocytes from tuberculous patients and healthy subjects are reported. factors isolated from human serum used in the experiments included the rosette inhibition factor (rif) from serum of tuberculous patients and the rosette restoring factor (rrf) from serum of healthy subjects. lymphocytes were fractionated on a discontinuous bsa gradient. lymphocytes from healthy subjects, sensitive to rif, as well as lymphocytes from tuberculous patients, sensitive to rr ... | 1979 | 117785 |
| antigenic changes associated with liver carcinogenesis. | carcinogen-induced experimental hepatomas are often characterized by new individually distinct antigens capable of inducing tumor immunity in syngeneic hosts. these antigens arise as a consequence of cell-carcinogen interaction and may result from modification or replacement of normal cell-surface components. their role in immunosurveillance is not established, but they offer a target for tumor immunotherapy. reexpressed fetal antigens have also been detected, either as secretory products (alpha ... | 1979 | 89200 |
| [etiotropic treatment of patients with calculous pyelonephritis]. | | 1979 | 118533 |
| magnetic susceptibility of microorganisms. | total magnetic susceptibility of 13 species and varieties of bacteria was investigated using the relative method of guy. it has been established that the index of magnetic susceptibility is a constant characteristic of bacteria. total magnetic susceptibility ranged from --0.3295.10(-6) in escherichia p678 to --0.4965.10(-6) in proteus. it has also been established that magnetic susceptibility changes during long-term passages of bacteria in fluctuating +/- 0.1 oe) magnetic field. this is suggest ... | 1979 | 118995 |
| demonstration of an alpha2-macroglobulin receptor in human fibroblasts, absent in tumor-derived cell lines. | | 1979 | 87392 |
| [differentiation of nonspecific serological reactions in brucellosis]. | differentiation of non-specific agglutination was performed by the complement binding reaction, coombs' reaction, hajdu reaction, the surface fixation and agglutination reaction and the reaction of complement binding with heterologic antigens. for that purpose the following were used: 1) serums--antiglobulin against cattle globulin, 5720 serum of various animals which had manifested non-specific agglutination with brucella antigen and brucella serums of experimentally infected sheep, of naturall ... | 1979 | 120633 |
| in vitro transformation of mouse bone marrow cells by the polycythemic strain of friend leukemia virus. | strains of friend leukemia virus (flv) that are associated with polycythemia contain the defective spleen focus-forming virus (sffv). to determine whether the transforming ability of flv was affected by the presence of this second agent, dba/2j mouse bone marrow cells were infected in vitro. criteria for transformation were the establishment of permanent lines, growth on semisolid agarose, and the production of tumors at the site of inoculation in syngeneic hosts. two lines of immature hematopoi ... | 1979 | 86991 |
| inhibitory effect of normal mammalian sera on the rosette formation of human lymphocytes with sheep red blood cells. | | 1975 | 123840 |
| effect of phospholipase a on active transport of amino acids with membrane vesicles of mycobacterium phlei. | active transport of proline remained unaffected in phospholipase a-treated electron transport particles from mycobacterium phlei. however, the steady state level of proline was reduced 50 to 60% in phospholipase a-treated depleted electron transport particles that were devoid of membrane-bound coupling factor-latent atpase activity. the decrease in the uptake of proline in the phospholipase a-treated depleted electron transport particles was not due to a change in the apparent k-m for proline, b ... | 1975 | 123919 |
| [intratypical antigenic differentiation of poliovirus strains circulating in mali by means of cross-adsorbed sera]. | the intratypic antigenic differentiation of poliovirus strains isolated from sick or healthy children in mali in 1975-1976 was performed. the method is based on the use of cross-adsorbed sera in the neutralization tests in which the virus is titrated by the plaque procedure or by the cytopathic effect. all the examined strains of serologic types i, ii, and iii were distinguished by the antigenic structure from the vaccine strains and were classified as "wild". quantitative differences in the ant ... | 1978 | 86237 |