| the presence of anti-lps antibodies and human serum activity against proteus mirabilis s/r forms in correlation with tlr4 (thr399ile) gene polymorphism in rheumatoid arthritis. | proteus mirabilis strains are human pathogens responsible for urinary tract infections, which may also be involved in rheumatoid arthritis (ra). | 2012 | 22749779 |
| bladder stones in catheterized spinal cord-injured patients in nigeria. | the objective was to determine the incidence of bladder stones in patients with spinal cord injury (sci) and to assess if catheter encrustation or positive urinary culture of proteus mirabilis is predictive of bladder stones. | 2016 | 22718163 |
| [plasmid-mediated ampc producing proteus mirabilis in the health care area of santiago de compostela: molecular and epidemiological analysis by rep-pcr and maldi-tof]. | proteus mirabilis is an important pathogen isolated from both community-acquired and health-care associated infections. acquired ampc-type beta-lactamases represent an important mechanism of resistance to extended-spectrum cephalosporins and are emerging in several european countries. the objective of this work was to know the prevalence of acquired ampc beta-lactamase producing p. mirabilis over the last three years and eight months and their clonal relationships comparing maldi-tof and automat ... | 2012 | 22707100 |
| [urinary tract nosocomial infections at the clinical centre in kragujevac]. | urinary tract infections are the most frequent hospital infections and account for about 40% of total hospital infections. the main risk factor for their development is the use of catheters. | 2012 | 22650105 |
| comparison of the binding specificity of two bacterial metalloproteases, lasb of pseudomonas aeruginosa and zapa of proteus mirabilis, using n-alpha mercaptoamide template-based inhibitor analogues. | the metalloproteases zapa of proteus mirabilis and lasb of pseudomonas aeruginosa are known to be virulence factors their respective opportunistic bacterial pathogens, and are members of the structurally related serralysin and thermolysin families of bacterial metalloproteases respectively. secreted at the site of infection, these proteases play a key role in the infection process, contributing to tissue destruction and processing of components of the host immune system. inhibition of these viru ... | 2012 | 22575503 |
| proteus mirabilis urinary tract infection and bacteremia: risk factors, clinical presentation, and outcomes. | proteus mirabilis is a common pathogen responsible for complicated urinary tract infections (utis) that sometimes causes bacteremia. most cases of p. mirabilis bacteremia originate from a uti; however, the risk factors for bacteremia and mortality rates from p. mirabilis uti have not been determined. | 2012 | 22572004 |
| characterization of a transmissible plasmid encoding veb-1 and vim-1 in proteus mirabilis. | | 2012 | 22547621 |
| virulence factors in proteus bacteria from biofilm communities of catheter-associated urinary tract infections. | more than 40% of nosocomial infections are those of the urinary tract, most of these occurring in catheterized patients. bacterial colonization of the urinary tract and catheters results not only in infection, but also various complications, such as blockage of catheters with crystalline deposits of bacterial origin, generation of gravels and pyelonephritis. the diversity of the biofilm microbial community increases with duration of catheter emplacement. one of the most important pathogens in th ... | 2012 | 22533980 |
| multidrug-resistant proteus mirabilis bloodstream infections: risk factors and outcomes. | our aims were to identify (i) risk factors associated with the acquisition of multidrug-resistant (mdr, to 3 or more classes of antimicrobials) proteus mirabilis isolates responsible for bloodstream infections (bsis) and (ii) the impact on mortality of such infections. risk factors for acquiring mdr p. mirabilis bsis were investigated in a case-case-control study; those associated with mortality were assessed by comparing survivors and nonsurvivors in a cohort study. the population consisted of ... | 2012 | 22450979 |
| bacteriology of infected burn wounds in the burn wards of a teaching hospital in southwest nigeria. | burns are characterized by the loss of varying proportions of the protective layers of the skin, depression of immune responses, and increased wound susceptibility to infection. wound infection is a major cause of morbidity and mortality in burn cases. this study characterizes those factors that predispose burn wounds to infection and the bacteriology of the microorganisms in our environment. | 2013 | 22386976 |
| antimicrobial activities against biofilm formed by proteus mirabilis isolates from wound and urinary tract infections. | bacterial species are capable of living as biofilm and/or planktonic forms. there is increasing evidence for the role of bacterial biofilm in various wound and urinary tract infections (utis). the aim of the present study was to evaluate the ability of the bacteria, isolated from urinary tract infections (utis) and wound infections, to form biofilm and correlate the role of biofilm with their antimicrobial resistance. | 2012 | 22361765 |
| chemical constituents and antibacterial activity of the leaf essential oil of feronia limonia. | the essential oil from the leaves of feronia limonia was extracted and the chemical constituents and antibacterial activity were studied. the gc and gc-ms analyses revealed that the leaf essential oil of f. limonia contained fourteen compounds representing about 98.4% of the total oil. the major chemical compounds identified were eudesma-4 (14).11-dine (46.3%), carvacrol (29.6%) and 1,5-cyclodecandine (13.4%). the essential oil was screened for its antibacterial activity against different clinic ... | 2010 | 22815575 |
| isolation and purification of complex ii from proteus mirabilis strain atcc 29245. | a respiratory complex was isolated from plasma membrane of pathogenic proteus mirabilis strain atcc 29245. it was identified as complex ii consisting of succinate:quinone oxidoreductase (ec 1.3.5.1) containing single heme b. the complex ii was purified by ion-exchange chromatography and gel filtration. the molecular weight of purified complex was 116.5 kda and it was composed of three subunits with molecular weights of 19 kda, 29 kda and 68.5 kda. the complex ii contained 9.5 nmoles of cytochrom ... | 2010 | 24031557 |
| concurrent neonatal proteus mirabilis infection in dizygotic twins. | a case of concomitant infection with proteus mirabilis in dizygotic twin neonates is presented. the first twin presented with meningitis and septic shock at eight days of age and subsequently died. an investigation of the asymptomatic second twin revealed a urinary tract infection that resolved with antimicrobial therapy. it is recommend that when infection with this virulent organism is diagnosed in one twin, the second twin should be fully evaluated for sepsis and empirical antimicrobial thera ... | 1999 | 22346381 |
| efficiency of hydrogen photoproduction by photosystem i-enriched subchloroplast vesicles combined with proteus mirabilis cells. effects of some exogenous electron donors. | high rates of hydrogen photoproduction are obtained when glutaraldehyde-fixed photosystem i-enriched vesicles (photosystem ii-depleted) are added to hydrogenase-containing cells of proteus mirabilis in the presence of the mediator methylviologen and a suitable electron donating system. this donor system includes ascorbate, dithioerythritol (dte) and the mediator tetramethylphenylene-diamine (tmpd) and reduces the photosynthetic electron transfer chain at the level of plastocyanin. both dte and a ... | 1984 | 24458776 |
| hematogenous proteus mirabilis osteomyelitis. | hematogenous gram negative infection of the long bones can present a confusing clinical picture that may delay treatment or lead to an inappropriate choice of initial treatment, and thereby compromise the resuit. this report emphasizes the common clinical features of this condition: previous urinary or gastrointestinal tract instrumentation, a long history of diffuse pain, swelling, and tenderness of the affected limb, weight loss and anorexia, and a potentially nondiagnostic radiographic appear ... | 1983 | 24823220 |
| chemical constituents of helichrysum italicum (roth) g. don essential oil and their antimicrobial activity against gram-positive and gram-negative bacteria, filamentous fungi and candida albicans. | the aerial parts of helichrysum italicum (roth) g. don were subjected to hydrodistillation to obtain essential oils which had been analyzed by gas chromatography and gas chromatography coupled with mass spectrometry and tested for antimicrobial activity against 12 bacteria, two yeasts and four fungi by agar diffusion method. the essential oil yielded 0.44% (v/w) and 67 compounds accounting for 99.24% of the oil were identified with a high content of oxygenated sesquiterpenes (61.42%). the most o ... | 2017 | 28725151 |
| in vitro antibacterial activity of poly (amidoamine)-g7 dendrimer. | nano-scale dendrimers are synthetic macromolecules that frequently used in medical and health field. traditional anibiotics are induce bacterial resistence so there is an urgent need for novel antibacterial drug invention. in the present study seventh generation poly (amidoamine) (pamam-g7) dendrimer was synthesized and its antibacterial activities were evaluated against representative gram- negative and gram-positive bacteria. | 2017 | 28583153 |
| [effects of vacuum sealing drainage technique in acute and chronic suppurative tenosynovitis of hand]. | objective: to investigate the effects of vacuum sealing drainage technique in acute and chronic suppurative tenosynovitis of hand. methods: a total of 9 cases acute and chronic suppurative tenosynovitis patients from january 2013 to april 2015 in puai hospital affiliated to tongji medical college, huazhong university of science and technology were retrospectively reviewed. there were 6 males and 3 females, aging from 27 to 65 years, the average age was 55 years. there were 3 cases of index finge ... | 2017 | 28464581 |
| monitoring in vitro antibacterial efficacy of 26 indian spices against multidrug resistant urinary tract infecting bacteria. | to screen methanolic extracts of 26 commonly used indian spices against nine species of uropathogenic bacteria (enterococcus faecalis, staphylococcus aureus, acinetobacter baumannii, citrobacter freundii, enterobacter aerogenes, escherichia coli, klebsiella pneumoniae, proteus mirabilis, and pseudomonas aeruginosa), isolated from clinical samples of a tertiary care hospital for antibacterial activity. | 2014 | 28664089 |
| antibacterial effects of lactobacillus isolates of curd and human milk origin against food-borne and human pathogens. | this study was undertaken to assess the antibacterial efficacy of lactobacilli isolated from curd and human milk samples. identities of thirty-one different lactobacilli (20 from curd and 11 from human milk) were confirmed by genus-specific pcr and 16s rrna-based sequencing. these strains belonged to five species, lactobacillus casei, l. delbrueckii, l. fermentum, l. plantarum, and l. pentosus. antibacterial activities of cell-free supernatants (cfss) of all the lactobacillus isolates were estim ... | 2017 | 28401466 |
| environmental monitoring and assessment of antibacterial metabolite producing actinobacteria screened from marine sediments in south coastal regions of karnataka, india. | assessment of the therapeutic potential of secondary metabolite producing microorganisms from the marine coastal areas imparts scope and application in the field of environmental monitoring. the present study aims to screen metabolites with antibacterial potential from actionbacteria associated with marine sediments collected from south coastal regions of karnataka, india. the actinobacteria were isolated and characterized from marine sediments by standard protocol. the metabolites were extracte ... | 2017 | 28534309 |
| the distribution of carbapenem- and colistin-resistance in gram-negative bacteria from the tamil nadu region in india. | the occurrence of carbapenem- and colistin-resistance among gram-negative bacteria is increasing worldwide. the aim of this study was to understand the distribution of carbapenem- and colistin-resistance in two areas in tamil nadu, india. | 2017 | 28671537 |
| bacterial genus is a risk factor for major amputation in patients with diabetic foot. | to evaluate whether bacterial genus is a risk factor for major amputation in patients with diabetic foot and infected ulcer. | 2017 | 28658333 |
| antimicrobial property of lemongrass (cymbopogon citratus) oil against pathogenic bacteria isolated from pet turtles. | the usage of essential oils as antimicrobial agents is gaining attention. besides, pet turtles were known to harbor a range of pathogenic bacteria while the turtle keeping is a growing trend worldwide.the current study examined the antimicrobial activity of lemon grass oil (lgo) against seven species of gram negative bacteria namely; aeromonas hydrophila, a. caviae, citrobacter freundii, salmonella enterica, edwardsiella tarda, pseudomonas aeruginosa, and proteus mirabilis isolated from three po ... | 2017 | 28747972 |
| bacterial species and mycotoxin contamination associated with locust bean, melon and their fermented products in south-western nigeria. | the microbiological safety of spontaneously fermented foods is not always guaranteed due to the undefined fermenting microbial consortium and processing materials. in this study, two commonly consumed traditional condiments (iru and ogiri) and their respective raw seeds (locust bean and melon) purchased from markets in south-western nigeria were assessed for bacterial diversity and mycotoxin contamination using 16s rrna gene sequencing and liquid chromatography tandem mass spectrometry (lc-ms/ms ... | 2017 | 28759798 |
| antimicrobial activity of endophytic bacterial populations isolated from medical plants of iran. | endophytic actinobacteria colonize inside the plant tissues without causing damages to the host plant. since these microorganisms colonize in the different parts of plants and can stop plant disease, they have been applied as biological agents for controlling human diseases. the aim of this study was molecular identification and measuring the antimicrobial activity of endophytic actinomycetes isolated from medicinal plants of iran. | 2017 | 28775818 |
| chemical composition of mentha pulegium and rosmarinus officinalis essential oils and their antileishmanial, antibacterial and antioxidant activities. | the aim of the study was the determination of the chemical composition of mentha pulegium l. and rosmarinus officinalis l. essential oils and the evaluation of their antileishmanial, antibacterial and antioxidant activities. essential oils (eos) were isolated using steam distillation and the chemical composition was determined using gc-ms analysis. the antibacterial activity was tested against ten pathogenic strains using the diffusion method, the minimum inhibitory concentration (mic) and the m ... | 2017 | 28821401 |
| [to the state of the fetoplacental complex in women with the threat of abortion]. | the goal is a comprehensive study of the morphofunctional state of the mother-placenta-fetus system in placental insufficiency and infection. 250 pregnant and puerperas for the period 2008-2014 were examined. detection of bacterial flora was carried out in 35 pregnant women aged 20.4±0.8 years with the threat of abortion from an early gestation period and a prolonged persistent infection of the genitals, bacterial vaginosis. methods are applied: culture, ion chromatography, gas-liquid chromatogr ... | 2017 | 28820412 |
| fungal bezoar: a rare cause of ureteral obstruction. | a 52-year-old male, with diabetes mellitus and alcoholic liver disease, presented to the emergency room for right flank pain of 3 days' duration, associated with dysuria. physical examination revealed right flank tenderness with fever and hypotension; laboratory findings showed acute kidney injury and large blood and leucocytes in the urine. a ct abdomen and pelvis showed hydronephrosis of the right collecting system of a horseshoe kidney with air and hyperdense debris in the renal pelvis. patie ... | 2017 | 28804662 |
| colorimetric sensing of toxic metal and antibacterial studies by using bioextract synthesized silver nanoparticles. | here, we report the simple and cost effective colorimetric technique for the determination of toxic metals (hg(2+)) in aqueous sample by using bioextract silver nanoparticles (agnps). the indigenous agnps were synthesised by green and ecologically friendly style using extract of fig (ficus carica) leaf. the synthesized agnps were confirmed by uv-vis spectroscopy, ft-ir spectroscopy, and scanning electron microscopy methods. the synthesis of agnps was observed by its colour changing from light ye ... | 2017 | 28748516 |
| the antimicrobial spectrum of xeroform(®). | xeroform(®) is a petrolatum-based fine mesh gauze containing 3% bismuth tribromophenate. bismuth, similar to other metals, has antimicrobial properties. xeroform(®) has been used for decades in burn and plastic surgery as a donor site dressing and as a covering for wounds or partial thickness burns. despite this, the antimicrobial spectrum of xeroform(®) remains largely unknown. we examined the in-vitro efficacy of xeroform(®) against common burn pathogens using zone-of-inhibition methodology in ... | 2017 | 28641915 |
| short ftsz filaments can drive asymmetric cell envelope constriction at the onset of bacterial cytokinesis. | ftsz, the bacterial homologue of eukaryotic tubulin, plays a central role in cell division in nearly all bacteria and many archaea. it forms filaments under the cytoplasmic membrane at the division site where, together with other proteins it recruits, it drives peptidoglycan synthesis and constricts the cell. despite extensive study, the arrangement of ftsz filaments and their role in division continue to be debated. here, we apply electron cryotomography to image the native structure of intact ... | 2017 | 28438890 |
| prophylactic use of intraoperative vancomycin powder and postoperative infection: an analysis of microbiological patterns in 1200 consecutive surgical cases. | objective wound infections following spinal surgery for deformity place a high toll on patients, providers, and the health care system. the prophylactic application of intraoperative vancomycin powder has been shown to lower the infection risk after thoracolumbar decompression and fusion for deformity correction. the purpose of this study was to assess the microbiological patterns of postoperative surgical site infections (ssis) after prophylactic use of vancomycin powder in adult patients under ... | 2017 | 28665245 |
| dissemination of bla oxa-370 gene among several enterobacteriaceae species in brazil. | oxa-370 is a recently described oxa-48 variant that has only been described in a few enterobacter spp. and klebsiella pneumoniae isolates. the purpose of this study is to assess the prevalence of oxa-370-producing isolates in carbapenem-nonsusceptible enterobacteriaceae recovered from 28 hospitals from brazil. real-time pcr was used to determine the presence of bla ndm-1, bla kpc-2, bla vim-type, bla ges-type, bla oxa-48-like, and bla imp-type genes. a total of 4,451 enterobacteriaceae were scre ... | 2017 | 28555403 |
| imipenem-resistant gram-negative bacterial isolates carried by persons upon medical examination in korea. | carbapenem-resistant gram-negative bacteria (cr-gnb) have emerged and disseminated worldwide, become a great concern worldwide including korea. the prevalence of fecal carriage of imipenem-resistant gram-negative bacteria (ir-gnb) in persons in korea was investigated. stool samples were collected from 300 persons upon medical examination. samples were screened for ir-gnb by using macconkey agar with 2 μl/ml imipenem. species were identified by 16s rrna gene sequence analysis, and antimicrobial s ... | 2017 | 28721477 |
| accelerated detection of extended-spectrum β-lactamases in clinical isolates of enterobacteriaceae. | a prospective study is carried out to evaluate the performance of a protocol for the accelerated detection of extended-spectrum β-lactamases (esbls) in clinical isolates of escherichia coli, klebsiella pneumoniae and other gram-negative bacteria. a modified double-disc test (mddt) is incorporated in a gram-negative template for routine susceptibility testing. the mddt identified accurately esbls in all isolates subsequently confirmed as esblproducers by the standard clinical laboratory standards ... | 2006 | 28700883 |
| assessment of facultative anaerobes from the root canals of deciduous molars: an in vivo study. | background. the current research aimed to assess the prevalence of facultative anaerobes isolated from the root canals of deciduous molars. methods. the present research enrolled 60 children in the 6‒9-year age group based on clinical and radiographic findings. under aseptic conditions, access cavities were prepared followed by collection of samples from infected root canals with the help of sterile paper points. the samples thus obtained were subjected for microbial assay. results. it was found ... | 2017 | 28748050 |
| spectrum and antibiotic resistance of uropathogens between 2004 and 2015 in a tertiary care hospital in hungary. | surveillance of the bacterial spectrum and antibiotic-resistance patterns of locally occurring uropathogens is essential to serve as a basis for empirical treatment of urinary tract infections (utis), as antibiotic-resistance rates may vary geographically with significant differences between countries and regions, and with time. | 2017 | 28621642 |
| collaborative research on puerperal infections in bangladesh. | bangladesh is considered as a high-risk country for emerging infectious diseases because of its high population density, poverty, and unhygienic conditions. although control efforts have primarily been focused on major infectious diseases such as diarrheal diseases, tuberculosis, malaria, and hiv infection, the prevalence and impact of many local or minor infectious diseases are still unclarified in this country. in this review, we present our recent experience and outcomes of collaborative rese ... | 2017 | 28552890 |
| influence of different wild-garlic (allium ursinum) extracts on the gastrointestinal system: spasmolytic, antimicrobial and antioxidant properties. | as there are no previous studies of the european wild-garlic (allium ursinum) effects on the gastrointestinal system, despite its traditional applications in gastrointestinal disorders' treatment and regular use in the human diet, we have quantified and compared spasmolytic, antimicrobial and antioxidant activities of its different leaf extracts. | 2017 | 28543032 |
| development of a panel of recombinase polymerase amplification assays for detection of common bacterial urinary tract infection pathogens. | to develop and evaluate the performance of a panel of isothermal real-time recombinase polymerase amplification (rpa) assays for detection of common bacterial urinary tract infection (uti) pathogens. | 2017 | 28510991 |
| antimicrobial resistance patterns in women with positive urine culture: does menopausal status make a significant difference? | aim. urinary tract infection (uti) is considered one of the most common bacterial infections in women. the aim of this study was to investigate the types of uropathogens present, as well as the degree of antimicrobial drug resistance seen among premenopausal (n = 2748) and postmenopausal (n = 1705) women with uncomplicated uti. methods. urinary samples (n = 4453) collected from women with uti were analyzed in terms of uropathogens present. these were considered as positive if bacterial growth wa ... | 2017 | 28497048 |
| recurrence of deep surgical site infection in cerebral palsy after spinal fusion is rare. | retrospective review of prospective registry. | 2017 | 28449964 |
| bacterial epidemiology and antimicrobial resistance profiles of urinary specimens of the elderly. | although urinary tract infections are the second leading cause of infections among patients aged above 65 years, data on bacterial epidemiology of urinary specimens in these patients is scarce. our aim was to describe the main bacterial species found at significant levels in urine specimens of the elderly and to determine their antimicrobial resistance profiles. | 2017 | 28408060 |
| prevalence study of plasmid-mediated ampc β-lactamases in enterobacteriaceae lacking inducible ampc from saudi hospitals. | enterobacteriaceae encoding plasmid-mediated ampc (pampc) β-lactamases confer resistance to the third generation cephalosporins. pampc association with extended spectrum β-lactamases (esbls), plasmid-mediated quinolone resistance (pmqr) and aminoglycoside modifying enzymes (ames) is well documented. there are limited data regarding the epidemiology and clinical significance of pampc in saudi arabia. this study aimed to determine the prevalence of pampc and its coexistence with esbls, pmqr and am ... | 2017 | 28820112 |
| evolving beta-lactamase epidemiology in enterobacteriaceae from italian nationwide surveillance, october 2013: kpc-carbapenemase spreading among outpatients. | extended-spectrum beta-lactamases (esbls), ampc-type beta-lactamases (acbls) and carbapenemases are among the most important resistance mechanisms in enterobacteriaceae. this study investigated the presence of these resistance mechanisms in consecutive non-replicate isolates of escherichia coli (n = 2,352), klebsiella pneumoniae (n = 697), and proteus mirabilis (n = 275) from an italian nationwide cross-sectional survey carried out in october 2013. overall, 15.3% of isolates were non-susceptible ... | 2017 | 28797330 |
| a novel type 1/2 hybrid incc plasmid carrying fifteen antimicrobial resistance genes recovered from proteus mirabilis in china. | incc plasmids are of great concern as vehicles of broad-spectrum cephalosporins and carbapenems resistance genes blacmy and blandm. the aim of this study was to sequence and characterize a multidrug resistance (mdr) incc plasmid (ppm14c18) recovered from proteus mirabilis. ppm14c18 was identified in a cmy-2-producing p. mirabilis isolate from chicken in china in 2014, and could be transferred to escherichia coli conferring an mdr phenotype. whole genome sequencing confirmed ppm14c18 was a novel ... | 2017 | 28757095 |
| propensity-matched analysis of the impact of extended-spectrum β-lactamase production on adults with community-onset escherichia coli, klebsiella species, and proteus mirabilis bacteremia. | the presence of extended-spectrum β-lactamase (esbl) in escherichia coli, klebsiella species, and proteus mirabilis (ekp) is of great microbiological and clinical importance. the study dealing with the direct impact of esbl producers on the outcome of patients with community-onset bacteremia is lacking. | 2017 | 28698042 |
| clinical benefits of antimicrobial de-escalation in adults with community-onset monomicrobial escherichia coli, klebsiella species and proteus mirabilis bacteremia. | the clinical benefits of an antimicrobial de-escalation strategy were compared with those of a no-switch strategy in bacteremic patients. adults with community-onset monomicrobial escherichia coli, klebsiella species and proteus mirabilis bacteremia treated empirically using broad-spectrum beta-lactams, including third-generation cephalosporins (gcs), fourth-gc or carbapenems, were treated definitively with first- or second-gcs (de-escalation group), the same regimens as empirical antibiotics (n ... | 2017 | 28694235 |
| expression, purification, and characterization of a membrane-bound d-amino acid dehydrogenase from proteus mirabilis jn458. | to characterize a novel membrane-bound d -amino acid dehydrogenase from proteus mirabilis jn458 (pmdad). | 2017 | 28676939 |
| effect of the 2014 clinical and laboratory standards institute urine-specific breakpoints on cefazolin susceptibility rates at a community teaching hospital. | enterobacteriaceae, which include escherichia coli, klebsiella pneumoniae, and proteus mirabilis, are identified as the infectious etiology in the majority of urinary tract infections (utis) in community hospitals across the united states. the minimum inhibitory concentration (mic) is a useful tool when choosing an appropriate antibacterial agent. recent changes to the 2014 clinical and laboratory standards institute (clsi) guidelines included reporting a urine-specific cefazolin breakpoint for ... | 2017 | 28558707 |
| development and characterization of a stable adhesive bond between a poly(dimethylsiloxane) catheter material and a bacterial biofilm resistant acrylate polymer coating. | catheter associated urinary tract infections are the most common health related infections worldwide, contributing significantly to patient morbidity and mortality and increased health care costs. to reduce the incidence of these infections, new materials that resist bacterial biofilm formation are needed. a composite catheter material, consisting of bulk poly(dimethylsiloxane) (pdms) coated with a novel bacterial biofilm resistant polyacrylate [ethylene glycol dicyclopentenyl ether acrylate (eg ... | 2017 | 28535686 |
| characterisation of a thiamine diphosphate-dependent alpha-keto acid decarboxylase from proteus mirabilis jn458. | alpha-keto acid decarboxylases can convert keto acids to their corresponding aldehydes, which are often volatile aroma compounds. the gene encoding α-keto acid decarboxylase in proteus mirabilis jn458 was cloned, and the enzyme overexpressed in escherichia coli bl21 (de3), purified in high yield, and characterised. the molecular weight is 62.291kda by maldi-tof ms, and optimum activity at ph 6.0 and 40-50°c. the enzyme is a typical decarboxylase, dependent on thiamine diphosphate and mg(2+) as c ... | 2017 | 28490063 |
| synergic bactericidal effects of reduced graphene oxide and silver nanoparticles against gram-positive and gram-negative bacteria. | reduced graphene oxide (rgo) is a promising antibacterial material, the efficacy of which can be further enhanced by the addition of silver nanoparticles (nag). in this study, the mechanisms of antibacterial activity of rgo-nag nanocomposite against several important human pathogenic multi-drug resistant bacteria, namely gram-positive coccal staphylococcus aureus and gram-negative rod-shaped escherichia coli and proteus mirabilis are investigated. at the same concentration (100 µg/ml), rgo-nag n ... | 2017 | 28484209 |
| assessment of urinary pharmacokinetics and pharmacodynamics of orbifloxacin in healthy dogs with ex vivo modelling. | the aim of this study was to investigate the urinary pharmacokinetics (pk) of orbifloxacin (obfx) administered at 5 mg kg-1 in six healthy dogs. a further aim was to use an ex vivo model to evaluate the urinary pk and pharmacodynamics (pd) of obfx to determine its urinary bactericidal titre (ubt), which represents the maximal dilution of urine allowing bactericidal activity. | 2017 | 28470147 |
| antibiofilm potential of synthetic 2-amino-5-chlorobenzophenone schiff bases and its confirmation through fluorescence microscopy. | antibacterial/antibiofilm potential of microwave-assisted synthetic thirty-three 2-amino-5-chloro benzophenone schiff bases have been carried out against four bacterial strains i.e. klebsiella pneumoniae, proteus mirabilis, staphylococcus aureus and streptococcus mutans. among them compounds 5, 6, 8, 9, 14, 16, 22, 24, 26, and 30-32 showed antibiofilm activities against isolates at less than 100 μg/ml concentrations. these compounds showed enhanced antibiofilm activity against s. aureus as compa ... | 2017 | 28755874 |
| antibiofilm potential of 16-oxo-cleroda-3, 13(14) e-diene-15 oic acid and its five new γ-amino γ-lactone derivatives against methicillin resistant staphylococcus aureus and streptococcus mutans. | the clerodane diterpenoids 16-oxo-cleroda-3, 13(14) e-diene-15 oic acid (1) and kolavenic acid (2) isolated from polyalthia longifolia var. pendula (linn.) were previously reported for their antimicrobial activity. thus present study was designed to investigate the biofilm inhibiting potential of these diterpenoids (1-2) and five new lactone derivatives (3-7) of 1 against methicillin resistant staphylococcus aureus (mrsa), streptococcus mutans, klebsiella pneumoniae and proteus mirabilis. compou ... | 2017 | 28692914 |
| formulation of carbapenems loaded gold nanoparticles to combat multi-antibiotic bacterial resistance: in vitro antibacterial study. | despite the fact that carbapenems (powerful β-lactams antibiotics) were able to fight serious infectious diseases, nowadays the spread of carbapenems-resistant bacteria is considered the main challenge in antibacterial therapy. in this study, we focused on evaluating the surface conjugation of carbapenems (imipenem and meropenem) with gold nanoparticles as a delivering strategy to specifically and safely maximize their therapeutic efficacy while destroying the developing resistance of the pathog ... | 2017 | 28411141 |
| lactococcus lactis as a safe and inexpensive source of bioactive silver composites. | this research develops a safe, inexpensive, and more accessible source for synthesis of silver nanoparticles. the bioactive silver composites synthesized by lactococcus lactis 56 ky484989 (lclb56-agcs) were characterized by various physico-chemical techniques and investigated for their antimicrobial activity and cytotoxicity. the average amount of nanoparticles was 0.363 ± 0.09 mg from 50 ml of culture medium. the synthesis efficiency varied from 71 to 85%. synthesized silver nanoparticles with ... | 2017 | 28842740 |
| oral immunisation with taishan pinus massoniana pollen polysaccharide adjuvant with recombinant lactococcus lactis-expressing proteus mirabilis ompa confers optimal protection in mice. | proteus mirabilis poses a critical burden on the breeding industry, but no efficient vaccine is available for animals. | 2017 | 28629671 |
| multidrug resistance salmonella genomic island 1 in a morganella morganii subsp. morganii human clinical isolate from france. | salmonella genomic island 1 (sgi1) is a multidrug resistance integrative mobilizable element that harbors a great diversity of antimicrobial resistance gene clusters described in numerous salmonella enterica serovars and also in proteus mirabilis. a serious threat to public health was revealed in the recent description in p. mirabilis of a sgi1-derivative multidrug resistance island named pgi1 (proteus genomic island 1) carrying extended-spectrum-β-lactamase (esbl) and metallo-β-lactamase resist ... | 2017 | 28435889 |
| a case of tetraplegia after proteus mirabilis infection. | | 2017 | 28855782 |
| postoperative nasal septal abscess following use of 2-octylcyanoacrylate and polydioxanone plate in open septorhinoplasty: a case series. | the employment of 2-octylcyanoacrylate adhesive (dermabond) to assist graft placement in open septorhinoplasty has been increasingly used to stabilize cartilage grafts. literature regarding this application has been mixed, with some showing the possibility of increased rates of inflammation, if not infection. we present an original comparative case series involving postoperative septal abscess formation adjacent to caudal strut grafting where both dermabond and an absorbable polydioxanone (pds) ... | 2017 | 28831833 |
| evaluation of biofilm-induced urinary infection stone formation in a novel laboratory model system. | infection stones comprise approximately 15% of all urinary tract stones and are induced by infection with urease-positive pathogens. the bacteria within the stone matrix present significant treatment impediments compared to metabolic kidney stones. while much is known about how urinary composition regulates metabolic stone formation, there is a general lack of knowledge around which urinary factors regulate the rate of infection stone formation. unfortunately, more in-depth research into infecti ... | 2017 | 28827106 |
| gc-ms analysis and gastroprotective evaluations of crude extracts, isolated saponins, and essential oil from polygonum hydropiper l. | peptic ulceration is among the most prevalent gastrointestinal disorders characterized by pepsin and gastric acid mediated mucosal damage, as result of imbalance between defensive and offensive processes. the main objective of the current study was to investigate the antiulcer potentials of polygonum hydropiper crude methanolic ectract (ph.cr) in aspirin induced ulcerogenesis using pylorus ligated rat model. in-vitro urease and proteus mirabilis inhibitory potentials were evaluated using standar ... | 2017 | 28824906 |
| camp receptor protein regulates mouse colonization, motility, fimbria-mediated adhesion, and stress tolerance in uropathogenic proteus mirabilis. | cyclic amp receptor protein (crp) is a major transcriptional regulator in bacteria. this study demonstrated that crp affects numerous virulence-related phenotypes, including colonization of mice, motility, fimbria-mediated adhesion, and glucose stress tolerance in uropathogenic proteus mirabilis. diabetic mice were more susceptible to kidney colonization by wild-type strain than nondiabetic mice, in which the crp mutant exhibited increased kidney colonization. loss of crp or addition of 10% gluc ... | 2017 | 28779108 |
| a shape-shifting redox foldase contributes to proteus mirabilis copper resistance. | copper resistance is a key virulence trait of the uropathogen proteus mirabilis. here we show that p. mirabilis scsc (pmscsc) contributes to this defence mechanism by enabling swarming in the presence of copper. we also demonstrate that pmscsc is a thioredoxin-like disulfide isomerase but, unlike other characterized proteins in this family, it is trimeric. pmscsc trimerization and its active site cysteine are required for wild-type swarming activity in the presence of copper. moreover, pmscsc ex ... | 2017 | 28722010 |
| septic arthritis of the pubis symphysis: clinical and therapeutic features. | septic arthritis of the pubis symphysis is rare and difficult to diagnose. the objective of our study was to describe the biological, clinical, radiological and therapeutic aspects of this disease. this is a retrospective study of 4 cases of septic arthritis of the pubic symphysis collected in the department of rheumatology and orthopaedics in sousse in tunisia over a period of 16 years (2000-2016). our population consists of 3 women and one men. the mean age was 47 years (18-83). clinical signs ... | 2017 | 28690730 |
| [proteus mirabilis septic arthritis]. | acute septic arthritis is rare. it is associated with poor prognosis in terms of mortality and morbidity. we report the case of a 61-year old patient with spontaneous proteus mirabilis septic arthritis. he suffered from complicated diabetes associated with positive blood cultures and synovial fluid cultures. patient's evolution was favorable thanks to early diagnosis and initiation of adequate antibiotic therapy. proteus mirabilis septic arthritis is rare. on that basis we conducted a literature ... | 2017 | 28674590 |
| genome-wide transposon mutagenesis of proteus mirabilis: essential genes, fitness factors for catheter-associated urinary tract infection, and the impact of polymicrobial infection on fitness requirements. | the gram-negative bacterium proteus mirabilis is a leading cause of catheter-associated urinary tract infections (cautis), which are often polymicrobial. numerous prior studies have uncovered virulence factors for p. mirabilis pathogenicity in a murine model of ascending uti, but little is known concerning pathogenesis during cauti or polymicrobial infection. in this study, we utilized five pools of 10,000 transposon mutants each and transposon insertion-site sequencing (tn-seq) to identify the ... | 2017 | 28614382 |
| genetic characteristic of class 1 integrons in proteus mirabilis isolates from urine samples. | proteus mirabilis is an opportunistic pathogen, commonly associated with complicated urinary tract infections (utis). utis caused by multidrug-resistant proteus mirabilis have increased worldwide. multidrug-resistance of gram-negative enteric bacteria is usually associated with class 1 integrons. | 2017 | 28612707 |
| identification and characterization of new members of the sxt/r391 family of integrative and conjugative elements (ices) in proteus mirabilis. | integrative and conjugative elements (ices) are self-transmissible chromosomal mobile elements that play significant roles in the dissemination of antimicrobial resistance genes. identification of the structures and functions of ices, particularly those in pathogens, improves understanding of the dissemination of antimicrobial resistance. this study identified new members of the sulfamethoxazole-trimethoprim (sxt)/r391 family of ices that could confer multi-drug resistance in the opportunistic p ... | 2017 | 28602701 |
| persistence of blacmy-2-producing proteus mirabilis in two gull colonies at a 1-year interval in southern france. | | 2017 | 28572037 |
| the link between proteus mirabilis, environmental factors and autoantibodies in rheumatoid arthritis. | rheumatoid arthritis (ra) is a relatively common and potentially disabling immune-mediated inflammatory systemic disease, predominantly affecting women and characterised by multiple small joint arthritis. extensive data supports the roles of genetic, environmental and microbial factors in the triggering and development of this disease. proteus mirabilis is considered as the main microbial culprit in the causation of ra. the evidence for the role of these microbes in ra and their links with commo ... | 2017 | 28516867 |
| phenotypic detection and antibiogram of β-lactamase-producing proteus species in a tertiary care hospital, india. | proteus species cause a variety of community- and hospital-acquired illnesses. synthesis of β-lactamases is the predominant mechanism for resistance to β-lactam antibiotics. among the β-lactamases, extended spectrum β-lactamases (esbls) and ampc β-lactamases are the most common. | 2017 | 28503342 |
| fourier transform infrared spectroscopy as a tool in analysis of proteus mirabilis endotoxins. | fourier transform infrared spectroscopy (ft-ir) was used to scan whole bacterial cells as well as lipopolysaccharides (lpss, endotoxins) isolated from them. proteus mirabilis cells, with chemically defined lpss, served as a model for the atr ft-ir method. the paper focuses on three steps of infrared spectroscopy: (1) sample preparation, (2) ir scanning, and (3) multivariate analysis of ir data (principal component analysis, pca). | 2017 | 28478562 |
| the impact of production of extended-spectrum β-lactamases on the 28-day mortality rate of patients with proteus mirabilis bacteremia in korea. | the incidence of proteus mirabilis antimicrobial resistance, especially that mediated by extended-spectrum β-lactamases (esbls), has increased. we investigated the impact of esbl production on the mortality of patients with p. mirabilis bacteremia in korea. | 2017 | 28468622 |
| genome sequence of a providencia stuartii strain isolated from luciliasericata salivary glands. | we present here the draft genome sequence of a providencia stuartii strain, derived from the salivary glands of larval lucilia sericata, a common blow fly important to forensic, medical, and veterinary science. the genome sequence will help dissect coinfections involving p. stuartii and proteus mirabilis, as well as blow fly-bacteria interactions. | 2017 | 28450516 |
| superficial swab versus deep-tissue biopsy for the microbiological diagnosis of local infection in advanced-stage pressure ulcers of spinal-cord-injured patients: a prospective study. | to assess the predictive value of superficial ulcer swab culture to make a microbiological diagnosis of deep wound infections in spinal cord injury (sci) patients with advanced-stage pressure ulcers. | 2017 | 28433727 |