PMID(sorted descending)
effects of commercial diazinon and imidacloprid on microbial urease activity in soil and sod.diazinon [o,o-diethyl o-2-isopropyl-6-methyl(pyrimidine-4-yl) phosphorothioate] and imidacloprid [1-(1-[6-chloro-3-pyridinyl]methyl)-n-nitro-2-imidazolidinimine] are applied to lawns for insect control simultaneously with nitrogenous fertilizers such as urea, but their potential effect on urease activity and nitrogen availability in turfgrass management has not been evaluated. urease activity in enzyme assays, washed cell assays, and soil slurries was examined as a function of insecticide concen ...200516091610
role of swarming in the formation of crystalline proteus mirabilis biofilms on urinary catheters.the care of many patients undergoing long-term bladder catheterization is frequently complicated by infection with proteus mirabilis. these organisms colonize the catheter, forming surface biofilm communities, and their urease activity generates alkaline conditions under which crystals of magnesium ammonium phosphate and calcium phosphate are formed and become trapped in the biofilm. as the biofilm develops it obstructs the flow of urine through the catheter, causing either incontinence due to l ...200516091430
elevated levels of igm and iga antibodies to proteus mirabilis and igm antibodies to escherichia coli are associated with early rheumatoid factor (rf)-positive rheumatoid arthritis.antibodies to proteus mirabilis were previously detected in patients with established rheumatoid arthritis (ra). we examined the prevalence of antibodies to p. mirabilis and their associations with ra in early synovitis patients.200516091399
structure of the o-polysaccharide and serological studies of the lipopolysaccharide of proteus mirabilis 2002.the structure of the o-polysaccharide of the lipopolysaccharide of proteus mirabilis 2002 was elucidated by chemical methods and 1h and 13c nmr spectroscopy. it was found that the polysaccharide consists of branched pentasaccharide repeating units having the following structure: [structure in text]. the o-polysaccharide of p. mirabilis 2002 has a common tetrasaccharide fragment with that of p. mirabilis 52/57 from serogroup o29, and the lipopolysaccharides of the two strains are serologically re ...200516084933
inhibitor-based methods for detection of plasmid-mediated ampc beta-lactamases in klebsiella spp., escherichia coli, and proteus mirabilis.non-beta-lactam inhibitor-based methods were evaluated for detecting plasmid-mediated ampc beta-lactamases in klebsiella spp., escherichia coli, and proteus mirabilis. using clsi methodology and disks containing cefotetan alone and in combination with 400 mug of boronic acid, 9 of 10 positive control strains and 54 of 55 ampc-pcr-positive clinical isolates were detected. importantly 71% and 40% of these clinical isolates were susceptible by routine testing to ceftriaxone and ceftazidime, respect ...200516081966
[design and improvement of an elective culture medium for bacteriological diagnosis of salmonella infection].experimental studies have provided a nutrient broth for elective accumulation of salmonella (ma broth) and a differential diagnostic culture medium for selective isolation of the causative agents of salmonella toxic infections. the ma broth is used for bacteriological isolation of salmonellae from the low-infected material and for a sanitary-and-bacteriological study of meat-and- sausage and other foods for this pathogen. a combination of high accumulating and inhibiting properties of the design ...200516078535
surveillance of antimicrobial resistance in bulgaria--a synopsis from bulstar 2003.we introduce bulgarian surveillance tracking antimicrobial resistance (bulstar) and make the first report on surveillance data for 2003. this longitudinal surveillance programme monitors the isolation and antimicrobial susceptibility of all clinically significant microorganisms isolated from blood cultures, cerebrospinal fluid, upper and lower respiratory tract, urine and wound samples in the participating microbiology laboratories. twenty eight public, 45 hospital and 6 private laboratories fro ...200516077213
gudair (ojd) vaccine self-inoculation: a case for early debridement. 200516053420
effects of lipopolysaccharides from gram-negative bacteria on the level of thiols in blood platelets.lipopolysaccharide (endotoxin, lps) activates blood platelets and stimulates generation of free radicals in these cells. the mechanism of platelet activation induced by lps is not known. the aim of the present study was to examine how glutathione (gsh) and other thiol-containing compounds are involved in the oxidative stress in blood platelets caused by lps. the hplc technique has been used on the analysis of non-protein thiols from human blood platelets treated with lipopolysaccharides of diffe ...200516049662
in vitro and in vivo antibacterial activities of cs-023 (ro4908463), a novel parenteral carbapenem.cs-023 (ro4908463, formerly r-115685) is a novel 1beta-methylcarbapenem with 5-substituted pyrrolidin-3-ylthio groups, including an amidine moiety at the c-2 position. its antibacterial activity was tested against 1,214 clinical isolates of 32 species and was compared with those of imipenem, meropenem, ceftazidime, ceftriaxone, ampicillin, amikacin, and levofloxacin. cs-023 exhibited a broad spectrum of activity against gram-positive and -negative aerobes and anaerobes, including methicillin-res ...200516048932
fatal herpes simplex virus infection in darier disease under corticotherapy.a 67-year-old man is presented with longstanding and severe darier disease treated by topical antiseptics and potent corticosteroids, in combination with oral glucocorticoids and etretinate. after cardiac bypass surgery in 1997, the patient experienced herpes simplex virus (hsv type-1) infection of the skin that was treated by intravenous aciclovir. in 2003, he presented a widespread atypical exacerbation of his darier disease, involving the face, trunk, buttocks, intertriginous areas and arms. ...200516048763
synthesis, spectra and biomimetic properties of copper(ii)-copper(ii) and copper(ii)-zinc(ii) binuclear complexes with cun5 chromophores.x-band electron spin resonance (esr) and uv-vis spectra of a homobinuclear [(bipy)2cu-e-im-cu(bipy)2](bf4)3 and a heterobinuclear [(bipy)2cu-e-im-zn(bipy)2](bf4)3 complexes, e-im=2-ethylimidazolate ion have been described as possible models for superoxide dismutase (sod). magnetic moment and esr spectral measurements of the homobinuclear complex have shown an antiferromagnetic exchange interaction. from ph-dependent esr and uv-vis spectral measurements studies, these complexes have been found to ...200416043054
application of electrospray ionization with fourier transform ion cyclotron resonance mass spectrometry for structural screening of core oligosaccharides from lipopolysaccharides of the bacteria proteus.electrospray ionization with fourier transform ion cyclotron resonance mass spectrometry (esi-fticrms) was used for screening and structural elucidation of core oligosaccharides isolated from lipopolysaccharides of bacteria of the genus proteus. mass spectra allowed the determination of the molecular masses with high accuracy and the estimation of the chemical heterogeneity of the samples. they did not, however, provide sufficient information to identify structural details of the branched oligos ...200516041825 antimicrobial agents are urgently needed for clinical use due to the increasing prevalence and spread of multidrug-resistant bacteria that are commonly responsible for serious and life-threatening diseases. the need to develop new agents that effectively overcome existing mechanisms of resistance displayed by bacteria resistant to currently available drugs has become paramount. tigecycline, the first in a new class of antimicrobials, the glycylcyclines, is an analogue of minocycline with add ...200516040625
antibacterial and antioxidant activities of ethanol extract from paullinia cupana mart.the antibacterial and antioxidant activity of the ethanol extract from paullinia cupana var. sorbilis mart. (sapindaceae) seeds, commonly called guarana, was assessed towards selected bacteria as well as in different antioxidant models. the extract, at a concentration between 16 and 128 microg/ml, showed a significant antibacterial effect expressed as minimum inhibitory concentration (mic) against both gram-negative and gram-positive bacteria. in particular, pseudomonas aeruginosa (mic=16 microg ...200516040216
antimicrobial susceptibility patterns of contemporary pathogens from uncomplicated urinary tract infections isolated in a multicenter italian survey: possible impact on guidelines.during 2004 four italian laboratories assessed the prevalence of antimicrobial resistance among uropathogens causing acute uncomplicated cystitis in female out-patients. a total of 600 urine samples from individuals aged 18-65 were studied. the overall prevalence of escherichia coli was 85.3%. klebsiella pneumoniae, staphylococcus saprophyticus, proteus mirabilis, enterococcus faecalis and other rarer species were far less represented. determination of the antibiotic susceptibility pattern of th ...200516038517
recalcitrant scoliosis in proteus syndrome.proteus syndrome is a rare congenital condition with various clinical features such as hemihypertrophy, macrodactyly, subcutaneous masses, brain-like hyperplasia of the soles and/or palms, epidermal naevi and scoliosis with other mesodermal malformations. multifocal overgrowth can affect various tissues causing severe functional and cosmetic disability, but intellectual and language development are mostly normal. orthopaedic problems include macrodactyly, hindfoot deformity, limb length inequali ...200516035717
extended-spectrum beta-lactamases.the first beta-lactamase was identified in an isolate of escherichia coli in 1940. to date, there are >130 tem-type and >50 sulfhydryl variable (shv)-type beta-lactamases, mainly in e. coli, klebsiella pneumoniae, and proteus mirabilis but also in other members of the enterobacteriaceae family and in some nonenteric organisms, such as acinetobacter species. the incidence of expanded-spectrum beta-lactamases (esbls) varies, depending on which area of the globe the isolates originate from. esbls r ...200516032564
preclinical evaluation of rapeseed, raspberry, and pine bark phenolics for health related effects.rapeseed, raspberry, and pine bark are promising bioactive sources of plant phenolics selected from among ca. 100 previously screened plant materials for in vitro preclinical evaluation of health related effects. phenolic extracts and isolated fractions of the selected materials were investigated for antioxidant, antimicrobial, antiinflammatory, and antimutagenic properties as well as for cell permeability. it was shown that rapeseed and pine bark phenolics and raspberry anthocyanins were good o ...200516028975
[species-specific detection of proteus vulgaris and proteus mirabilis by the polymerase chain reaction].sets of primers for the species-specific detection of p. mirabilis and p. vulgaris by the polymerase chain reaction (pcr) were developed. as targets for these primers beta-lactamase and 16s rrna gene fragments were chosen on the basis of the multiple leveling of the sequences of the dna of all known p. mirabilis and p. vulgaris isolates. for differential detection oligonucleotides were selected in such a way that primers, specific for p. vulgaris, contained the non-paired nucleotide for p. mirab ...200516028510
pyrrolobenzodiazepine dimers: novel sequence-selective, dna-interactive, cross-linking agents with activity against gram-positive bacteria.pyrrolo[2,1-c][1,4]benzodiazepine (pbd) dimers are synthetic sequence-selective interstrand dna minor-groove cross-linking agents developed from anthramycins. we investigated the antibacterial activity of three dimers, sjg-136, drg-16 and elb-21, which differ in the structure of the pbd monomeric unit and the length of the linker region between the two identical pbd monomers.200516024592
colouterine fistula mimicking pyometrium--diagnosis established with multi-detector computed tomography. 200516022134
molecular characterization of multidrug-resistant proteus mirabilis isolates from retail meat products.sixty-four multidrug-resistant isolates of proteus mirabilis were collected from retail meat products in oklahoma. the isolates showed four different patterns of antibiotic resistance based on their resistant phenotype and genotypes. most of these isolates were resistant to ampicillin, tetracycline, gentamycin, and kanamycin. class 1 integrons were detected as a common carrier of the antibiotic-resistant genes, such as aada1, aadb, and aada2. a few isolates (9%) contained class 2 integrons with ...200516013378
swarmer cell differentiation in proteus mirabilis.under the appropriate environmental conditions, the gram-negative bacterium proteus mirabilis undergoes a remarkable differentiation to form a distinct cell type called a swarmer cell. the swarmer cell is characterized by a 20- to 40-fold increase in both cell length and the number of flagella per cell. environmental conditions required for swarmer cell differentiation include: surface contact, inhibition of flagellar rotation, a sufficient cell density and cell-to-cell signalling. the different ...200516011745
[synthesis and antibacterial activity of 3-(5-substituted phenyl-[1,3,4] oxadiazole-2-yl-methylenethio)-5-pyridin-3-yl-[1,2,4] triazole-4-yl-amines].to study on synthesis and antibacterial activity evaluation of polyheterocycles.200516011262
proteus syndrome: an update.proteus syndrome is a complex disorder consisting variably of disproportionate, asymmetric overgrowth of body parts; cerebriform connective tissue nevi; epidermal nevi; vascular malformations of the capillary, venous, and lymphatic types; and dysregulated adipose tissue. serious complications may ensue, such as pulmonary embolism, cystic lung disease, and various neoplasms. somatic mosaicism, lethal in the nonmosaic state, is the best working hypothesis. although proteus syndrome data are consis ...200516010681
etiological and clinical patterns of childhood urolithiasis in iraq.this study was conducted to evaluate the etiological and clinical characteristics of urolithiasis in iraqi children. from 1999 to 2004, 204 children with renal calculi were evaluated. the age range of the patients was 4 months to 14 years, 61.3% of the patients were under 5 years. male to female ratio was 2.8:1. the mean age at onset of symptoms was 3.2 years, and stone disease was diagnosed at a mean of 3.5 years. hematuria (44.6%) and pain (28.4%) were the main clinical presentation. of the 20 ...200516010596
analysis of pten gene mutations in korean patients with cowden syndrome and polyposis syndrome.pten (phosphatase and tensin homologue deleted in chromosome 10) is a candidate tumor suppressor gene. mutations of this gene are responsible for pten hamartoma tumor syndromes, including cowden syndrome, bannayan-riley-ruvalcaba syndrome, proteus syndrome, and proteus -like syndromes. recently, pten mutations were identified in several human neoplasms. we analyzed the dna of various organs and lesions in korean patients with cowden syndrome, their family members, and patients with familial aden ...200516007494
evaluation of cd4(+)/cd8(+) status and urinary tract infections associated with urinary schistosomiasis among some rural on urinary schistosomiasis in nigeria are mainly epidemological. the knowledge of co-infections of urinary schistosomiasis and other pathogens are important epidemiological tools for the control and health benefits of the rural dwellers. the granulomatous reactions in urinary schistosomiasis is cd4(+) dependent. the cd8(+) is cytotoxic to parasites and it is activated by cd4(+). these parameters therefore participate in the immune responses to urinary schistosomiasis.200516006219
[xanthogranulomatous pyelonephritis: presentation of an unusual case].xanthogranulomatous pyelonephritis is a morphologically and clinically unique manifestation of chronic pyelonephritis with the formation of pus or granulomas. the most frequent predisposing factors for the development of xanthogranulomatous pyelonephritis are urinary obstruction (e. g., stones, tumors, congenital anomalies and functional impairment) and infection of the collecting system.200516001341
ampc disk test for detection of plasmid-mediated ampc beta-lactamases in enterobacteriaceae lacking chromosomal ampc beta-lactamases.although plasmid-mediated ampc beta-lactamases were first reported in the late 1980s, many infectious disease personnel remain unaware of their clinical importance. these enzymes are typically produced by isolates of escherichia coli, klebsiella spp., proteus mirabilis, and salmonella spp. and are associated with multiple antibiotic resistance that leaves few therapeutic options. plasmid-mediated ampc beta-lactamases have been associated with false in vitro susceptibility to cephalosporins. many ...200516000421
[long-term efficacy of trus-guided transperineal needle aspiration and irrigation on persistent hematospermia].to evaluate the long-term efficacy of transrectal ultrasonography (trus)-guided transperineal needle aspiration and irrigation for persistent hematospermia.200515999493
aetiology of catheter-associated bacteriuria in lagos university teaching hospital.a prospective study to determine the causative agents of catheter-related bacteriuria was carried out on 99 patients with median age of 55 years, on admission in the oncology, paediatric surgery and obstetric and gynaecology wards of the lagos university teaching hospital. there was significant bacteriuria in seventy-one (72%) of the 99 urine samples. all catheter urine samples were contaminated by day 5 gram-negative bacilli were predominant (89.3%) of which pseudomonas aeruginosa (26.2%) was t ...200515997255
selective iga immune unresponsiveness to proteus mirabilis fumarate reductase a-chain in rheumatoid determine if selective immune unresponsiveness to microbial antigens is associated with predisposition to rheumatoid arthritis (ra).200515996053
clinical management and outcome of childhood lung abscess: a 16-year order to evaluate the clinical manifestations, management and outcome of childhood lung abscess, a retrospective chart review of 27 pediatric patients with international classification of diseases, ninth revision-clinical modification (icd-9 cm) code of 503.1 (lung abscess) from august 1987 to august 2003 was conducted. among the 27 patients (14 males and 13 females), 30% (8/27) were primary lung abscess and 70% (19/27) had underlying chronic diseases (secondary lung abscess). the predisposin ...200515986068
proteus: identifying signatures in protein termini.proteus (protein terminus) is a web-based tool for the identification of short linear signatures in protein termini. it is based on a position-based search method for revealing short signatures in termini of all proteins. the initial step in proteus development was to collect all signature groups (sigs) based on their relative positions at the termini. the initial set of sigs went through a sequential process of inspection and removal of sigs, which did not meet the attributed statistical thresh ...200515980469
peptides selected for binding to a virulent strain of haemophilus influenzae by phage display are bactericidal.nontypeable haemophilus influenzae (nthi) is an obligate parasite of the oropharynx of humans, in whom it commonly causes mucosal infections such as otitis media, sinusitis, and bronchitis. we used a subtractive phage display approach to affinity select for peptides binding to the cell surface of a novel invasive nthi strain r2866 (also called int1). over half of the selected phage peptides tested were bactericidal toward r2866 in a dose-dependent manner. five of the clones encoded the same pept ...200515980377
proteus mirabilis bloodstream infections: risk factors and treatment outcome related to the expression of extended-spectrum beta-lactamases.bloodstream infection (bsi) due to proteus mirabilis strains is a relatively uncommon clinical entity, and its significance has received little attention. this study was initiated to evaluate risk factors and treatment outcome of bsi episodes due to p. mirabilis producing extended-spectrum beta-lactamases (esbls). twenty-five bsi episodes caused by p. mirabilis occurred at our hospital (ospedale di circolo e fondazione macchi, varese, italy) over a 7.5-year period. phenotypic and molecular metho ...200515980325
structure of the o-polysaccharide of proteus mirabilis oc (ccug 10702) from a new proposed proteus serogroup o75.a neutral o-polysaccharide was obtained by mild acid degradation of the lipopolysaccharide of proteus mirabilis oc (ccug 10702) and studied by sugar and methylation analyses and (1)h and (13)c nmr spectroscopy. the following structure of the tetrasaccharide repeating unit of the polysaccharide was established: [structure: see text]. based on the unique structure of the o-polysaccharide and serological data, we propose classifying p. mirabilis oc (ccug 10702) into a new separate proteus serogroup ...200515979596
bioactivity guided isolation of antimicrobial compounds from lythrum salicaria.lythrum salicaria extracts showed activity against the phytopathogenic fungus cladosporium cucumerinum and activity against the bacteria staphylococcus aureus, proteus mirabilis and microccocus luteus. bioautography on thin-layer chromatograms was used to isolate the two antifungal triterpenoids oleanolic and ursolic acid. the hexahydroxydiphenoyl ester vescalagin was isolated as active principle of the antibacterial activity. furthermore, the flavon-c-glucosides vitexin, isovitexin, orientin an ...200515975734
antimicrobial susceptibility pattern of blood isolates from a teaching hospital in north india.bloodstream infections are associated with significant patient morbidity and mortality worldwide. in this study, we examined antimicrobial susceptibility patterns by reviewing the data on 5,704 blood samples that were collected from patients with fever/sepsis admitted to government medical college and hospital, chandigarh, india, over a period of 1 year from august 2003 to july 2004. among the 567 qualifying samples, pseudomonas aeruginosa (19.75%), escherichia coli (15.17%), klebsiella pneumoni ...200515973011
noninvasive biophotonic imaging for monitoring of catheter-associated urinary tract infections and therapy in mice.urinary tract infections (utis) are among the most common bacterial infections acquired by humans, particularly in catheterized patients. a major problem with catheterization is the formation of bacterial biofilms on catheter material and the risk of developing persistent utis that are difficult to monitor and eradicate. to better understand the course of utis and allow more accurate studies of in vivo antibiotic efficacy, we developed a catheter-based biofilm infection model with mice, using bi ...200515972473
[antibiotic resistance transformation in community-acquired urinary infections].to detect the prevalence of uropathogens in community-acquired urinary tract infection in our environment, and the degree of sensitivity to antibiotics used as empirical treatment.200515970133
in-vitro antibacterial, antifungal and cytotoxic properties of sulfonamide--derived schiff's bases and their metal complexes.a series of new antibacterial and antifungal schiff's bases derived from sulfonamides, as well as their transition metal complexes incorporating cobalt (ii), copper (ii), nickel (ii) and zinc (ii) were synthesized, characterized and screened for their in-vitro antibacterial activity against six gram-negative (escherichia coli, klebsiella pneumoniae, proteus mirabilis, pseudomonas aeruginosa, salmonella typhi and shigella dysentriae) and four gram-positive (bacillus cereus, corynebacterium diphth ...200515968823
first description of dha-1 ampcbeta-lactamase in proteus mirabilis.this report describes the first occurrence of the dha-1 ampcbeta-lactamase gene in proteus mirabilis. the organism was isolated from the vaginal flora of a pregnant woman in a french hospital. the dha-1 beta-lactamase gene was identified on the basis of phenotypic characteristics, pcr amplification and sequencing. antagonism between cefoxitin and the other cephalosporins suggested inducible production of the dha-1 enzyme.200515966982
spread of novel expanded-spectrum beta-lactamases in enterobacteriaceae in a university hospital in the paris area, 2002, 28 non-duplicate enterobacterial isolates producing extended-spectrum beta-lactamases (esbls) were collected from infected patients at the bicêtre hospital in paris, france. escherichia coli was the predominant esbl-positive enterobacterial species, comprising ten (36%) of the isolates. ctx-m enzymes (ctx-m-3, ctx-m-10, ctx-m-14 and ctx-m-15) were produced by 11 (39%) of the isolates (six e. coli, two enterobacter cloacae, one enterobacter aerogenes, one proteus mirabilis and one citrob ...200515966981
dentomaxillofacial imaging in proteus syndrome.proteus syndrome is a rare condition that involves atypical growth of the bones, skin and head and a variety of other symptoms. only a few authors have reported on the craniofacial manifestations so far. the authors present a case of a 7-year-old girl with proteus syndrome in which the facial skeleton showed unilateral overgrowth. the analysis of the radiological evaluation revealed a bialveolar prognathism, a skeletal class iii, a dolicocephalic growth pattern and a left convex face scoliosis. ...200515961602
directed evolution and phenomics screening of new biocatalysts.biodiversity screening and directed evolution are two fruitful complementary approaches for the discovery and design of novel biocatalysts. a new technology for directed evolution, l-shuffling, has been designed and patented by proteus. l-shuffling technology offers several competitive advantages over other technologies including (i) directed evolution of large genes: l-shuffling" means "large-shuffling"; (ii) high fidelity recombination and (iii) control over location and frequency of recombina ...200115954596
adaptation to extreme environments: macromolecular dynamics in complex systems.what we previously thought of as insurmountable physical and chemical barriers to life, we now see as yet another niche harbouring 'extremophiles'. extremophiles and their macromolecules had to develop molecular mechanisms of adaptation to extreme physico-chemical conditions. using neutron spectroscopy, we have demonstrated that molecular dynamics represents one of these molecular mechanisms of adaptation. to which extent do hyper-saline conditions and extreme temperatures influence molecular dy ...200515951115
sesquin, a potent defensin-like antimicrobial peptide from ground beans with inhibitory activities toward tumor cells and hiv-1 reverse antifungal peptide with a molecular mass around 7 kda and an n-terminal sequence highly homologous to defensin was isolated from ground beans (vigna sesquipedalis cv. 'ground bean'). the peptide was adsorbed on affi-gel blue gel and on mono s. it exerted an antifungal action on botrytis cinerea, fusarium oxysporum and mycosphaerella arachidicola; and an antibacterial action on escherichia coli b, proteus vulgaris, mycobacterium phlei and bacillus megaterium. the antimicrobial activity was inh ...200515949629
characterisation of the rac/pak pathway in amoeba proteus.molecular mechanisms underlying the unique locomotion of the highly motile amoeba proteus still remain poorly understood. recently, we have shown that blocking the endogenous amoebal rac-like protein(s) leads to distinct and irreversible changes in the appearance of these large migrating cells as well as to a significant inhibition of their locomotion. to elucidate the mechanism of the rac pathway in amoeba proteus, we tested the effects of blocking the endogenous myosin i heavy chain kinase (mi ...200515948264
synthesis of schiff bases of 2-amino-5-aryl-1,3,4-oxadiazoles and their evaluation for antimicrobial activities.twenty schiff bases of 2-amino-5-aryl-1,3,4-oxadiazoles have been synthesized with different aromatic aldehydes. the structures of the compounds were confirmed by nitrogen analysis, ir and 13c-nmr spectral data. the antibacterial properties of the compounds were investigated against proteus mirabilis (mtcc-425), pseudomonas aeruginosa (mtcc-424), bacillus subtilis (mtcc-619) and staphylococcus aureus (mtcc-96) using the broth dilution method. the most active compounds were 4c (64 microg/ml), 4f ...200515942874
effect of ph and of urea on nitrofurantoin activity. 196715938307
plasmid-mediated, inducible ampc beta-lactamase (dha-1)-producing enterobacteriaceae at a korean hospital: wide dissemination in klebsiella pneumoniae and klebsiella oxytoca and emergence in proteus mirabilis.the aim of the study was to investigate the phenotypic and genetic characteristics of recently emerging cefoxitin-resistant and induction-positive isolates of escherichia coli, klebsiella species, and proteus mirabilis. strains of enterobacteriaceae were isolated at a korean tertiary care hospital between june and december 2002. induction was tested using cefoxitin and aztreonam disks, the bladha allele was detected by pcr, and pulsed-field gel electrophoresis (pfge) patterns were also analyzed. ...200515936167
organisms causing urinary tract infection in pediatric patients at ayub teaching hospital abbottabad.urinary tract infection (uti) is common in pediatric practice and an important cause of morbidity and mortality in children. infected urine stimulates an immunological and inflammatory response leading to renal injury and scarring, ultimately leading to end stage renal failure. the present study identifies the micro organisms causing urinary tract infection in children presenting with uti at ayub teaching hospital, abbottabad.200515929535
preventive and therapeutic administration of an indigenous lactobacillus sp. strain against proteus mirabilis ascending urinary tract infection in a mouse model.probiotics are increasingly being considered as non-pharmaceutical and safe potential alternatives for the treatment and prevention of a variety of pathologies including urinary tract infections. these are the most common infections in medical practice and are frequently treated with antibiotics, which have generated an intense selective pressure over bacterial populations. proteus mirabilis is a common cause of urinary tract infections in catheterised patients and people with abnormalities of t ...200515928974
sternal split approach to the cervicothoracic junction in children.we present a descriptive case series outlining the surgical technique and outcome in six patients managed with a combined anterior neck and sternal splitting approach.200515928540
characterization of a cdna of peroxiredoxin ii responding to hydrogen peroxide and phagocytosis in amoeba proteus.phagocytic cells have defense systems against reactive oxygen species generated as the first non-specific defense mechanism against invading pathogens or microorganisms. we cloned a cdna encoding a 21.69-kda protein in amoeba proteus homologous to 2-cys peroxiredoxin (prx-ap). in the disk inhibition assay using h2o2 as an oxidizing agent, escherichia coli overproducing prx-ap showed better viability than did e. coli transformed with pbluescript ii sk for control. monoclonal antibodies (mab) prod ...200515926998
modeling and designing a proteomics application on proteus.biomedical applications, such as analysis and management of mass spectrometry proteomics experiments, involve heterogeneous platforms and knowledge, massive data sets, and complex algorithms. main requirements of such applications are semantic modeling of the experiments and data analysis, as well as high performance computational platforms. in this paper we propose a software platform allowing to model and execute biomedical applications on the grid.200515924180
using ontologies in proteus for modeling proteomics data mining applications.bioinformatics applications are often characterized by a combination of (pre) processing of raw data representing biological elements, (e.g. sequence alignment, structure prediction), and an high level data mining analysis. developing such applications needs knowledge of both data mining and bioinformatics domains, that can be effectively achieved by combining ontology about the application domain and ontology about the approaches and processes to solve the given problem. in this paper we talk a ...200515923712
microbial persistence: a clinical reminder. 200515913172
polymicrobial osteomyelitis of the odontoid process with epidural abscess: case report and review of literature.osteomyelitis of the odontoid process is a rare disease and staphylococcus aureus is the usual causative organism. we present a case caused by a synergistic infection with staphylococcus aureus and proteus mirabilis, which has not been reported previously. a high index of suspicion is required for diagnosis, and early institution of broad antimicrobial therapy, including agents active against gram-negative organisms, is mandatory.200315912167
characterization of amoeba proteus myosin vi immunoanalog.amoeba proteus, the highly motile free-living unicellular organism, has been widely used as a model to study cell motility. however, molecular mechanisms underlying its unique locomotion and intracellular actin-based-only trafficking remain poorly understood. a search for myosin motors responsible for vesicular transport in these giant cells resulted in detection of 130-kda protein interacting with several polyclonal antibodies against different tail regions of human and chicken myosin vi. this ...200515909304
straightforward representation of antimicrobial chemotherapeutics susceptibility profiles in a private tertiary care hospital.culture-based values for antimicrobial susceptibility of 28 antimicrobials against different bacteria isolated from clinical material in a tertiary care hospital were used to pick the most promising antimicrobials. isolates originating from urinary tract, blood and pyogenic foci, enteric fever and enteritis were grouped. antimicrobials, systemic or oral, exhibiting a 75% or more susceptibility were compartmentalized in relation to divergent clinical disorders. retrospective categorized culture-b ...200515904968
enteric bacteria mandibular osteomyelitis.osteomyelitis of the mandible is a relatively rare inflammatory disease that usually stems from the odontogenic polymicrobial flora of the oral cavity. we are reporting 2 unusual cases of mandibular osteomyelitis resulting from enteric bacteria infection. in one patient, abundant clinical evidence suggested a diagnosis of a chronic factitious disease, whereas in the second patient no obvious etiology was found.200515897844
prulifloxacin versus ciprofloxacin in the treatment of adults with complicated urinary tract infections.the present study was performed to evaluate the efficacy and safety of a 10-day regimen of prulifloxacin 600 mg once daily as compared to ciprofloxacin 500 mg twice daily in the treatment of patients with complicated urinary tract infections (utis).200515897698
vulgarinin, a broad-spectrum antifungal peptide from haricot beans (phaseolus vulgaris).from the seeds of haricot beans (phaseolus vulgaris), an antifungal peptide with a molecular mass around 7 kda was purified by using a simple protocol consisting of affinity chromatography on affi-gel blue gel and gel filtration on superdex 75. this peptide named vulgarinin manifested an antifungal activity toward fungal species such as fusarium oxysporum, mycosphaerella arachidicola, physalospora piricola and botrytis cinerea, and an antibacterial action on mycobacterium phlei, bacillus megater ...200515896669
successfully treated mitral valve proteus mirabilis endocarditis.infective endocarditis caused by proteus mirabilis is rare and is fatal in most cases. a case of a 64-year-old man presenting with fever, dysuria, and murmur is reported. p mirabilis endocarditis was diagnosed based on clinical presentation, blood culture findings, and the presence of a large mitral valve vegetation seen on echocardiogram. the patient survived after long-term antibiotics and surgical replacement of the mitral valve. the clinical characteristics and complications from reported ca ...200515894870
outbreaks of contaminated broncho-alveolar lavage related to intrinsically defective bronchoscopes.from 5 march 2001 to 19 october 2001, outbreaks of broncho-alveolar lavage (bal) contamination with enterobacteraceae were detected in our 700-bed institution. we report the investigation of these outbreaks. a case was defined as the occurrence of pairs of specific enterobacteraceae in bal specimens among any patients who underwent bronchoscopy in the respiratory unit during the period of the outbreak. contamination was identified in 117 bal samples during three outbreaks among 418 patients, and ...200515893850
structure of a lactic acid ether-containing and glycerol phosphate-containing o-polysaccharide from proteus mirabilis o-polysaccharide was isolated by mild acid hydrolysis from the lipopolysaccharide of proteus mirabilis o40 and studied by nmr spectroscopy, including 2d 1h, 1h cosy, tocsy, roesy, and 1h, 13c hmqc experiments, along with chemical methods. the polysaccharide was found to contain an ether of glcnac with lactic acid and glycerol phosphate in the main chain and to have the following structure: --> 3)-beta-d-glcpnac4(r-lac)-(1 --> 3)-alpha-d-galp-(1 --> 3)-d-gro-1-p-(o --> 3)-beta-d-glcpnac-(1 --> ...200515890320
oropharyngeal flora changes in patients with head and neck malignancy post radiotherapy.radiotherapy has been recognized as a valuable modality of treatment in the management of head and neck cancers. it can have a direct bactericidal effect on the normal flora of the oropharynx. the objective of this study is to determine the changes in the oropharyngeal flora after external beam radiation. this prospective non randomized control study was performed to aid in identification of organisms involved in sepsis, as well as aid in choosing appropriate antibiotics for surgical procedures ...200415889559
antagonistic activity of a natural fungal population towards pathogenic bacteria. an in vitro the present work, we performed in vitro testing of 33 species of fungi of the subdivision deuteromycotina isolated from water and sediment of the kolubara river for antagonistic action towards 11 species of pathogenic bacteria. of gram-negative bacteria, the species most sensitive to metabolic fluid of the fungi were proteus mirabilis, salmonella enteritidis, and shigella sonnei, while the most resistant were klebsiella pneumoniae and salmonella typhimurium. of gram-positive bacteria, the mos ...200515889346
early extreme contradictory estimates may appear in published research: the proteus phenomenon in molecular genetics research and randomized trials.divergent results on the same scientific question generate controversy. we hypothesized that controversial data are attractive to investigators and editors, and thus the most extreme, opposite results would appear very early rather than late, as data accumulate, provided data can be generated rapidly.200515878467
antibacterial potential from indian suregada angustifolia.phytochemical analysis of the leaves from indian suregada angustifolia (baill. ex muell. arg.) airy shaw (euphorbiaceae) resulted in the isolation and identification of six known compounds, viz. friedelin, epi-friedelinol, n-octacosanol, alpha-amyrin, beta-sitosterol and beta-sitosterol-3-beta-d-glucopyranoside. aqueous (room temperature, boiled and autoclaved) and various solvent (methanol, chloroform and hexane) extracts of leaves were tested against 12 human pathogenic bacteria by the agar we ...200515878247
detection of anti-dsdna by elisa using different sources of compare different sources of dna for use in elisa-based assays for anti-dsdna antibody detection in systemic lupus erythematosus (sle) diagnosis.200515875736
antibiotic resistance of urinary pathogens in female general practice patients.a cross-sectional study was performed to determine the prevalence of antibiotic resistance in women with uncomplicated and complicated lower urinary tract infection (uti) in germany. in 36 (of 118 invited) general practices, urine cultures and resistance testing were performed during 4 months on all women presenting with symptoms of uti. each patient's symptoms, risk factors and treatment were documented. a total of 445 women were included, and their median age was 53 y. complicating factors wer ...200515871164
childhood urinary tract infection: a clinical analysis of 597 cases.objectives of study: to gain new insights into the epidemiology, genitourinary (gu) tract anomalies, etiologies, susceptibility of urinary pathogens to antibiotics in children with urinary tract infection (uti) during the past decade in taiwan.200415868848
urinary tract infection in children: incidence of vesicoureteral reflux, imaging studies, and antimicrobial resistance among e. coli. 200415868844
the rssab two-component signal transduction system in serratia marcescens regulates swarming motility and cell envelope architecture in response to exogenous saturated fatty acids.serratia marcescens swarms at 30 degrees c but not at 37 degrees c on a nutrient-rich (lb) agar surface. mini-tn5 mutagenesis of s. marcescens ch-1 yielded a mutant (wc100) that swarms not only vigorously at 37 degrees c but also earlier and faster than the parent strain swarms at 30 degrees c. analysis of this mutant revealed that the transposon was inserted into a gene (rssa) predicted to encode a bacterial two-component signal transduction sensor kinase, upstream of which a potential response ...200515866926
bacteriological study of diabetic foot infections.the polymicrobial nature of diabetic foot infection has been well documented in the literature. patients with diabetic foot infection not exposed to antibiotics are not well studied before. the relative frequency of bacterial isolates cultured from community-acquired foot infections that are not exposed to antimicrobial agents for 30 days is studied. in addition, the bacterial comparative in vitro susceptibility to the commonly used antibacterial agents is assessed.200515866058
bacterial infections--the cause of preterm delivery.within diagnostic procedures protocols in preterm delivery, the objective of the study was to examine bacterial causes of preterm deliveries in relation to term deliveries. the study included 106 patients delivered before term (24 to 37 weeks of gestation) and 126 patients with term delivery after 37 to 42 weeks of gestation. bacterial analysis included hospital material: cervix smear in patients before the delivery and protective and functional fetal elements.200515864934
evolution of skin lesions in proteus syndrome.proteus syndrome is a rare overgrowth disorder that is generally progressive, but the natural history of the skin lesions is not known.200515858474
occurrence and molecular analysis of extended-spectrum {beta}-lactamase-producing proteus mirabilis in hong kong, 1999-2002.a study was conducted to evaluate the occurrence and characterization of extended-spectrum beta-lactamases (esbls) among blood isolates of proteus mirabilis collected over a 4 year period in hong kong.200515857942
detection of paragonimus heterotremus eggs in experimentally infected cats by a polymerase chain reaction-based method.a polymerase chain reaction (pcr) procedure for the detection of paragonimus heterotremus eggs in stool samples was developed and compared with stoll's egg count method. the primers were designed on the basis of a previously constructed pph-13-specific dna probe, which produced an approximate 0.5-kb amplified product. this pcr method could detect as few as 5 eggs in 0.6 g of artificially inoculated feces of a healthy control cat or as little as 1 x 10(-4) ng of p. heterotremus genomic dna. the a ...200515856902
a potent sperm motility-inhibiting activity of bioflavonoids from an ethnomedicine of onge, alstonia macrophylla wall ex a. dc, leaf extract.the methanol extract (me) and the n-butanol fractions of methanolic extract of alstonia macrophylla wall ex a. dc leaves were investigated on the forward motility (fm) of mammalian (goat and human) spermatozoa. the me at 600 microg ml-1 as well as fraction b at 100 microg ml-1 concentrations showed marked inhibition of sperm fm in both goat and human species when tested by microscopic and spectrophotometric methods. approximately 60-80% of the goat spermatozoa lost their fm when treated with 600 ...200515854639
[in vitro susceptibilites to levofloxacin and various antibacterial agents of 11,475 clinical isolates obtained from 52 centers in 2002].the susceptibilities of bacteria to fluoroquinolones (fqs), especially levofloxacin, and other antimicrobial agents were investigated using 11,475 clinical isolates collected in japan during 2002. methicillin susceptible staphylococci, streptococcus pyogenes, streptococcus pneumoniae, moraxella catarrhalis, the family of enterobactericeae, haemophilus influenzae and acinetobacter spp. exhibited stable and high susceptibilities to fqs. the rate of fqs-resistant mrsa was 80 approximately 90%, bein ...200515849869
an ethnobotanical survey of bauchi state herbal plants and their antimicrobial activity.a survey of medicinal plants used locally in the treatment of various diseases was carried out in bauchi state-nigeria. a total of 84 medicinal plants were listed. preliminary antimicrobial activity of the aqueous extracts of the plants was investigated. the results indicated that out of 84 plants, 75 exhibited antimicrobial activity against one or more of the test organisms at a concentration of 200 mg/ml. the extracts were found to show potentially interesting activity against proteus mirabili ...200515848012
effects of rate of infusion and probenecid on serum levels, renal excretion, and tolerance of intravenous doses of cefoxitin in humans: comparison with cephalothin.using a randomized crossover design, 1-g intravenous doses of cephalothin and cefoxitin, a cephalosporinase-resistant cephamycin, were infused into 12 normal adult males over periods of 120, 30, and 3 min, the last with and without prior intravenous infusions of probenecid (1 g). mean peak serum concentrations of antibiotic activity after cephalothin infusions were 23, 56, 103, and 102 mug/ml, respectively, and after cefoxitin infusions they were 27, 74, 115, and 125 mug/ml, respectively. proben ...197415830485
susceptibility of clinical isolates of bacteria to cefoxitin and cephalothin.the susceptibility of 4,929 unselected clinical isolates of bacteria to cefoxitin and cephalothin was determined by the single-disk method, using a computer-associated electronic zone analyzer to obtain, record, and process measurements of sizes of zones of inhibition. both cefoxitin and cephalothin were effective against most gram-positive strains, including staphylococcus aureus, s. epidermidis, micrococci, and all streptococci except enterococci. the three strains of listeria monocytogenes te ...197415830480
cefoxitin and cephalothin: antimicrobial activity, human pharmacokinetics, and toxicology.cefoxitin, a semisynthetic cephamycin, has been compared with the widely used parenteral cephalosporin, cephalothin, in terms of antibacterial activity, human pharmacokinetics, and toxicity. for both compounds, minimal inhibitory concentrations were within the therapeutic range against the 156 gram-positive cocci tested (except group d streptococci), but cephalothin was 8 to 20 times more active. regarding the 313 gram-negative organisms tested, both antibiotics were of approximately equal activ ...197415830475
treatment of pneumonia and other serious bacterial infections with cephapirin.nineteen patients with pneumonia due to streptococcus pneumoniae, staphylococcus aureus, klebsiella pneumoniae, or escherichia coli were treated with 4 to 18 g of cephapirin daily. there were three treatment failures. one patient each with pneumonia due to e. coli or s. pneumoniae died despite apparent eradication of the pathogen. lobar pneumonia due to k. pneumoniae progressed during therapy in a third patient to lung gangrene, necessitating pneumonectomy. five additional patients with pneumoco ...197415830473
new antimicrobial nitrofuran, trans-5-amino-3-[2-(5-nitro-2-furyl)vinyl]-delta2-1,2,4-oxadiazole: antimicrobial efficacy in mice, rats, and guinea pigs.a new antimicrobial nitrofuran designated sq 18,506 showed some therapeutic activity when administered orally to mice infected with escherichia coli, salmonella schottmuelleri, shigella flexneri, or klebsiella pneumoniae. animals infected parenterally with streptococcus pyogenes, proteus mirabilis, mycobacterium tuberculosis, and candida albicans, or topically with trichophyton mentagrophytes, did not respond to therapy with the drug at the dosage levels used. the compound was as effective as me ...197415830472
gram-negative bacterial resistance to cephalosporins in community-acquired infections in turkey.cephalosporins are widely used and trustworthy antibiotics in daily medical practice. although antibacterial resistance has been reported in hospital wards, there are less data for community-acquired infections. in this study we investigated the cephalosporin susceptibility profiles of community-acquired gram-negative bacteria isolates in sivas kizilay medical center (turkey) between march 2002 and march 2003. in our study, 949 escherichia coli, 165 proteus spp., 97 enterobacter spp., 24 klebsie ...200515828445
cefamandole, a cephalosporin antibiotic with an unusually wide spectrum of activity.the in vitro activity of cefamandole, 7-d-mandelamido-3-(1 methyl-1h-tetrazol-5 yethiomethyl)-3-cephem-4 carboxylic acid, was investigated. the majority of streptococci and pneumococci were inhibited by 0.1 mug/ml. activity against staphylococcus aureus was below that of cephalothin, but most strains were inhibited by 0.4 mug/ml. enterococci were not inhibited by less than 25 mug/ml. cefamandole was very active against most members of the enterobacteriaceae, with 70% of escherichia coli, 86% of ...197415828189
cefoxitin, a semisynthetic cephamycin antibiotic: antibacterial spectrum and resistance to hydrolysis by gram-negative beta-lactamases.the in vitro activity of cefoxitin, 3-carbamolyloxymethyl-7-alpha-methoxy-7[2-(2-thienyl)acetamido]-3-cephem-4-carboyxlic acid, was investigated. activity against gram-positive organisms was less than that of cephalothin and cephloridine. it was highly active against gram-negative bacilli, with activity against escherichia coli, proteus mirabilis, and klebsiella pneumoniae equal to that of currently available cephalosporins. in addition, it was active against certain enterobacter strains, serrat ...197415828188
butirosin compared with gentamicin in vitro and in vivo.butirosin (btn) (p. w. k. woo, g. l. coffey, h. w. dion, s. a. fusari, and g. d. senos, u. s. patent 3,541,078, 1970) is a new aminoglycoside antibiotic notably active against opportunist bacterial species within pseudomonas, klebsiella, enterobacter, serratia, and proteus. numerous comparative tests were carried out with btn and gentamicin (gtm) in vitro and in experimental infections in mice. btn was more active in mueller-hinton broth than in agar, but its activity was lessened at acid ph or ...197415828182
combined activity of sulfamethoxazole, trimethoprim, and polymyxin b against gram-negative bacilli.the activity of the three two-drug combinations of sulfamethoxazole (smx), trimethoprim (tmp), and polymyxin b (pb) against 52 clinical isolates of gram-negative bacilli was studied by a "checkerboard" agar dilution method. the organisms studied included strains of enterobacter spp., klebsiella pneumoniae, serratia marcescens, providence, proteus, and pseudomonas aeruginosa. the majority of these isolates were resistant to at least two of the three agents used in the combined studies and to the ...197415828175
r-mediated beta-lactamases and episomal resistance to the beta-lactam drugs in different bacterial hosts.ten penicillinase plasmids of varying taxonomic origin were studied after transfer to a variety of bacterial hosts. nine of the ten plasmids specified enzymes with the following identical, or very similar, properties: substrate profile, molecular weight, susceptibility to heat and inhibitors, and electrophoretic mobility, i.e., tem-like enzymes. the tenth r-mediated beta-lactamase was a cephalosporinase. plasmids with tem-like enzymes mediated resistance patterns identical towards the beta-lacta ...197415828172
childhood parapneumonic pleural effusion in review the epidemiological pattern and clinical features, management and outcome of childhood parapneumonic pleural effusion in enugu.200515827593
[severe community-acquired pneumonia due to proteus mirabilis]. 200515826556
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