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[vascular malformations (i). concept, classification, pathogenesis and clinical features].vascular malformations are anomalies always present at birth that, contrary to hemangiomas, never regress and may grow during lifetime. clinical presentation of vascular malformations is extremely variable and ranges from asymptomatic spots of mere aesthetic concern to lesions with high blood flow or located in critical sites that may be life-threatening. given the low incidence of these disorders it is difficult to establish therapeutic guidelines. in addition to a correct classification of vas ...200717504698
antibacterial effects of home-made resin salve from norway spruce (picea abies).resin salve made from norway spruce (picea abies) is traditionally used in folk medicine to heal skin ulcers and infected wounds. its antimicrobial properties were studied against certain human bacteria important in infected skin wounds. the sensitivity of the resin against gram-positive and gram-negative bacteria was studied in vitro by methods that are routinely used in microbiology laboratories. the resin salve exhibited a bacteriostatic effect against all tested gram-positive bacteria but on ...200717504300
identification of bacteria on the surface of clinically infected and non-infected prosthetic hip joints removed during revision arthroplasties by 16s rrna gene sequencing and by microbiological culture.it has been postulated that bacteria attached to the surface of prosthetic hip joints can cause localised inflammation, resulting in failure of the replacement joint. however, diagnosis of infection is difficult with traditional microbiological culture methods, and evidence exists that highly fastidious or non-cultivable organisms have a role in implant infections. the purpose of this study was to use culture and culture-independent methods to detect the bacteria present on the surface of prosth ...200717501992
new triazole and triazolothiadiazine derivatives as possible antimicrobial agents.triazole and triazoles fused with six-membered ring systems are found to possess diverse applications in the fields of medicine, agriculture and industry. the new 1,2,4-triazole and 1,2,4-triazolo[3,4-b][1,3,4]thiadiazine derivatives were synthesized as novel antimicrobial agents. the reaction of 1h-indol-3-acetic acid with thiocarbohydrazide gave the 4-amino-3-mercapto-5-[(1h-indol-3-yl)methyl]-4h-1,2,4-triazole. the reaction of triazole with arylaldehydes in ethanol gave the 4-arylideneamino-3 ...200817499887
[septic arthritis of the wrist].septic arthritis of the wrist is correlated with a high morbidity. to show diagnostic and therapeutic options we reviewed the patients treated with wrist infections at our institution for one year.200717497607
transmission in the community of clonal proteus mirabilis carrying vim-1 metallo-beta-lactamase.several infections among patients attending our outpatient clinic were caused by imipenem-resistant proteus mirabilis that were phenotypically metallo-beta-lactamase (mbl)-positive. the aim of the study was to investigate this extrahospital dissemination and the mechanisms of resistance to carbapenems.200717491004
co-expression of cyclin d1 and phosphorylated ribosomal s6 proteins in hemimegalencephaly.hemimegalencephaly (hmeg) is a developmental brain malformation highly associated with epilepsy. balloon cells (bcs) and cytomegalic neurons (cns) are frequently observed in hmeg specimens. cytomegaly in developmental brain malformations may reflect in aberrant activation of the mtor and beta-catenin signaling cascades, known regulators of cell size. we hypothesized that there is aberrant co-expression of phospho-ribosomal s6 (p-s6) protein, a downstream effector of the mtor cascade, as well as ...200717483958
bacterial contamination of ophthalmic solutions used in an extended care facility.to assess the frequency of contamination of ophthalmic solutions in a long-term care facility and to describe the characteristics of contaminated solutions.200717475711
psoas abscess ten years after ipsilateral nephrectomy for pyonephrosis.pyogenic abscess of the psoas muscle is a rare disease. the authors report a recently observed case which developed 10 years after ipsilateral nephrectomy for pyonephrosis, reviewing the pertinent literature. the culture of the pus extracted only reproduced proteus mirabilis. the relation between psoas abscess and nephrectomy is unclear. to make diagnosis is important to consider this condition in differential diagnosis in presence of fever and flank tenderness in a nephrectomized patient.200717475114
bacteriological study of pyogenic meningitis with special reference to latex agglutination.bacterial meningitis is an important and frequent devastating disease. the present study was carried out to determine the prevalence of pyogenic meningitis in our hospital in children and to find out the sensitivity of gram stain, crp and latex agglutination tests for the diagnosis of pyogenic meningitis from csf sample. out of 150 csf samples studied, 40 were diagnosed as pyogenic meningitis. h. influenzae was the commonest organism (22.5%), followed by streptococcus pneumoniae 15%, staphylococ ...200717474275
synthesis of isomeric, oxathiolone fused chalcones, and comparison of their activity toward various microorganisms and human cancer cells line.isomeric oxathiolone fused chalcones were prepared by condensation of appropriate acetylbenzo[1,3]oxathiol-2-ones with benzaldehydes under acidic conditions. the synthesized compounds were screened for cytotoxic activity using hela cells, as well as for antibacterial activity against micrococcus luteus, staphylococcus aureus, salmonella typhimurium, escherichia coli, proteus vulgaris, antifungal activity against candida albicans, and tuberculostatic activity against mycobacterium tuberculosis h( ...200717473478
efficacy of a silicone urinary catheter impregnated with chlorhexidine and triclosan against colonization with proteus mirabilis and other uropathogens.we sought to develop an infection-resistant urinary catheter. we evaluated 3 types of catheters for their efficacy against uropathogens in an in vitro model of the urinary tract. the catheter impregnated with chlorhexidine and triclosan suppressed the growth of uropathogens, including proteus mirabilis, for 20-30 days or longer.200717464922
a novel amoeba proteus 120 kda actin-binding protein with only 1 filamin repeat and a coiled-coil region.a novel 120 kda actin-binding protein (apabp-f1) was found in amoeba proteus. it was distributed throughout the cytoplasm, mainly in the subplasma membrane and perinuclear-nuclear areas, enriched in actin. the full-length cdna of apabp consisted of 2672 nucleotides with an open reading frame of 878 amino acids, giving a ~95 kda protein with a theoretical pi value of 5.11. it had a novel domain organization pattern: the n terminus (residues 1-104) contained 1 calponin-homology (ch) domain, follow ...200717464342
canine cathelicidin (k9cath): gene cloning, expression, and biochemical activity of a novel pro-myeloid antimicrobial peptide.cathelicidins, a group of cationic peptides found in leukocytes and epithelial cells, play a central role in the early innate immune defense against infection. although these host defense peptides have been reported in several mammalian species, including primates, no cathelicidins have been identified in carnivores. here we report the cloning, tissue expression and biological activity of a novel canine cathelicidin (k9cath). the full-length cdna sequence of k9cath encodes a predicted 172 amino ...200717462733
albomycin is an effective antibiotic, as exemplified with yersinia enterocolitica and streptococcus pneumoniae.albomycin belongs to the class of sideromycins, compounds composed of iron carriers linked to antibiotic moieties. albomycin was found to be active against bacteria that have a functional ferric hydroxamate transport system meaning that bacteria will actively transport albomycin until they die. we examined the activity spectrum of albomycin for bacterial pathogens and found that enterobacteriaceae except species of proteus and morganella were sensitive. resistance in the two genera was due to th ...200717459767
proteus mirabilis: a rare cause of infectious endocarditis.native valve endocarditis resulting from proteus mirabilis is an exceptionally rare entity. to date, 10 cases have been reported. we present a case of a 58-y-old female with fevers, bacteremia, and embolic phenomenon. unlike previous cases, early antibiotic treatment precluded valvular repair or death, leading to a favorable outcome.200717454908
urinary tract infection in patients with short-term indwelling.seventy patients (44(62.9%) females) requiring short-term urinary bladder catheterisation at the kenyatta national hospital, nairobi formed the study population. their mean ages +/- sd was 41+/- 26 years (range 13-100 years). the common indications and objectives for catheterisation included keeping the environment dry (41.1%), relieving urinary retention (27.0%) and urinary incontinence (24.3%). urinary tract infection (uti) was documented in 48 (68.6%) of the patients. the commonest infection ...199617451307
pattern and multiple drug resistance of bacterial pathogens isolated from wound infection at university of gondar teaching hospital, northwest ethiopia.antibiotics resistance among bacteria is a worldwide problem. the situation in developing countries like ethiopia is particularly serious. since the presence of drug resistant bacteria in the environment are threat for public health, up-to-date information on local pathogens and drug sensitivity pattern is very crucial to treat patients. the aim of this study is to assess the pattern of bacterial pathogens from wound infection and their susceptibility to common antibiotics.200617447374
education and imaging. gastrointestinal: abdominal abscess associated with a ventriculoperitoneal shunt. 200717444867
[susceptibility of clinical isolates from primary care clinics to oral antibacterial agents].the antimicrobial susceptibility of clinical isolates from specimens of patients in primary care clinics in 2005 was investigated by determining the minimum inhibitory concentrations of oral antibacterial agents. the numbers of test strains were 550 for gram-positive aerobes, 700 for gram-negative aerobes, and 150 for anaerobes. cefcapene (cfpn), cefditoren (cdtr), and cefteram (cftm) showed the most potent activities against staphylococcus spp. and streptococcus spp. among the cephems tested an ...200717436860
[isolation, identification, phylogenetic analysis and related properties of a pathogen in silurus meridionalis chen].in october 2005, a large number of adults of silurus meridionalis chen died in the mud fish farming of sichuan province. later, three predominate strains of bacteria were isolated from the body of moribund fish. by artificial infection tests, strain twn3 was confirmed to be the pathogen of the disease. based on the characteristics of morphology, physiology and biochemistry tests, twn3 was initially identified as proteus vulgaris, and its g + c content of dna is 39.1% . after being amplified, the ...200717436614
increasing resistance according to patient's age and sex in escherichia coli isolated from urine in italy.the prevalence of escherichia coli among the uropathogens routinely isolated in non-hospital laboratories (labs) and its susceptibility profiles were investigated. thirty-three labs were selected throughout italy. in vitro assays were performed by means of disk diffusion according to the clsi. females were prevalent (79.9%) and the mean patient age was 58.6 (sd 20.4) years. overall, the prevalence of e. coli was 55.3% (1375 strains), with enterococcus spp 10.2 %, proteus mirabilis 4.8%, coagulas ...200717434824
in vitro activity of ceftibuten at sub-inhibitory concentrations in comparison with other antibiotics against respiratory and urinary tract pathogens.some new features of the in vitro activity of ceftibuten, an oral third generation cephalosporin, have been studied in reference to respiratory and urinary tract pathogens included in its antibacterial spectrum. at 0.25xmic (minimum inhibitory concentration) and 0.5xmic levels, ceftibuten was able to affect the biofilm production in 2/3 of both escherichia coli and proteus mirabilis strains, and reduced the number of strains capable of adhering to epithelial cells by about 35% in comparison to t ...200717434823
mutation screening of the pten gene in patients with autism spectrum disorders and macrocephaly.mutations in the pten gene are associated with a broad spectrum of disorders, including cowden syndrome (cs), bannayan-riley-ruvalcaba syndrome, proteus syndrome, and lhermitte-duclos disease. in addition, pten mutations have been described in a few patients with autism spectrum disorders (asds) and macrocephaly. in this study, we screened the pten gene for mutations and deletions in 88 patients with asds and macrocephaly (defined as >or=2 sd above the mean). mutation analysis was performed by d ...200717427195
antiviral and antimicrobial profiles of selected isoquinoline alkaloids from fumaria and corydalis species.in the current study, 33 isoquinoline alkaloids belonging to protopine-, benzylisoquinoline-, benzophenanthridine-, spirobenzylisoquinoline-, phthalideisoquinoline-, aporphine-, protoberberine-, cularine-, and isoquinolone-types as well as 7 derivatives of them obtained from some fumaria and corydalis species growing in turkey have been evaluated for their in vitro antiviral and antimicrobial activities. both dna virus herpes simplex (hsv) and rna virus parainfluenza (pi-3) were employed for ant ...200717425100
survival of proteus mirabilis o3 (s1959), o9 and o18 strains in normal human serum (nhs) correlates with the diversity of their outer membrane proteins (omps).urinary tract infections are frequently caused by proteus mirabilis strains. in the previous studies there were defined the complete structures of o-polysaccharide parts of lipopolysaccharides from strains: p. mirabilis o3 (s1959), p. mirabilis o9 and p. mirabilis o18. in the present study it was investigated bactericidal effect of normal human serum (nhs) to p. mirabilis strains. we also focused on the diversity of outer membrane proteins (omps) being separated on a gel isolated from tested str ...200617419294
microbiologic profile of flexible endoscope disinfection in two brazilian hospitals.[corrected] endoscopes are routinely used in hospitals and clinics of the world and they can be potential sources of cross-infection when the decontamination process is unsuitable200617406750
mini-tn7 insertion in bacteria with secondary, non-glms-linked atttn7 sites: example proteus mirabilis hi4320.we previously constructed a series of mini-tn7 chromosome integration vectors that, when provided only with the site-specific transposition machinery, generally transpose to a naturally evolved, neutral atttn7 site that is located 25-bp downstream of the glms gene. here we provide a protocol for application of the mini-tn7 system in proteus mirabilis as an example of a bacterium with a secondary atttn7 site that is not linked to glms but, in this case, located in the carab operon. the procedure ...200617406229
population-based laboratory surveillance for tribe proteeae isolates in a large canadian health region.the tribe proteeae comprises the genera proteus, morganella and providencia. few studies have specifically investigated the epidemiology of infections caused by the proteeae, and none has been conducted in a large non-selected population. the present study was a population-based laboratory surveillance in the calgary health region (population 1.2 million), canada during 2000-2005 that aimed to define the incidence, demographical risk-factors for acquisition and antimicrobial susceptibilities of ...200717403132
a new antibacterial compound produced by an indigenous marine bacteria--fermentation, isolation, and biological activity.the use of microorganisms for biological purpose has become an effective alternative to control pathogens. a marine bacterium pseudomonas aeruginosa was isolated from eal fish of baluchistan coast of pakistan. this strain produced a bactericidal antibiotic against environmental and clinical isolates. in this study, we purified bactericidal antibiotic from the ethyl acetate extract of the cells of p. aeruginosa and analyzed its chemical structure. based on spectrometric analysis, this compound 1 ...200617393659
segmental overgrowth, lipomatosis, arteriovenous malformation and epidermal nevus (solamen) syndrome is related to mosaic pten nullizygosity.we describe two patients from distinct cowden disease families with specific germline pten mutations whose disease differs from the usual appearance of cowden disease. their phenotype associates classical manifestations of cowden disease and congenital dysmorphisms including segmental overgrowth, arteriovenous and lymphatic vascular malformations, lipomatosis and linear epidermal nevus reminiscent of the diagnosis of proteus syndrome. we provide evidence in one of the two patients of a secondary ...200717392703
type 2 segmental cowden disease vs. proteus syndrome. 200717388921
predictors of mortality in patients with bloodstream infections caused by extended-spectrum-beta-lactamase-producing enterobacteriaceae: importance of inadequate initial antimicrobial treatment.bloodstream infections (bsi) caused by extended-spectrum beta-lactamase (esbl)-producing organisms markedly increase the rates of treatment failure and death. we conducted a retrospective cohort analysis to identify risk factors for mortality in adult in-patients with bsi caused by esbl-producing enterobacteriaceae (esbl-bsi). particular attention was focused on defining the impact on the mortality of inadequate initial antimicrobial therapy (defined as the initiation of treatment with active an ...200717387156
potency and spectrum of garenoxacin tested against an international collection of skin and soft tissue infection pathogens: report from the sentry antimicrobial surveillance program (1999-2004).the spectrum and potency of garenoxacin, a novel des-f(6)-quinolone, against a large international collection (11723 strains) of gram-positive and gram-negative bacterial pathogens that cause skin and soft tissue infections (sstis) were evaluated for the years 1999 to 2004. consecutive nonduplicate bacterial isolates were collected from patients with documented community-acquired or nosocomial ssti in >70 medical centers participating in the sentry antimicrobial surveillance program in north ame ...200717383139
[evaluation of vitek 2 performance for identifying extended spectrum beta-lactamases in enterobacteriaceae "other than escherichia coli, proteus mirabilis and klebsiella spp"].production of beta-lactamases is the main resistance mechanism of gram-negative bacteria against beta-lactam antibiotics. extended spectrum beta-lactamases (esbls) have the ability to hydrolyze a broader spectrum of beta-lactam drugs. hence rapid, accurate detection of this resistance mechanism is extremely important to guide proper patient antimicrobial therapy. these enzymes are most commonly produced by klebsiella spp. and escherichia coli, but may also occur widely in other gram-negative bac ...200617380089
an in vitro assessment of the antibacterial effect of garlic (allium sativum) on bacterial isolates from wound infections.garlic (allium sativum) has come to be seen as an all rounded treatment for preventing wound infection, common cold, malaria, cough and lung tuberculosis, hypertension, sexually transmitted diseases, mental illness, kidney diseases, liver diseases, asthma, diabetes.200617370439
phytochemisty and spermatogenic potentials of aqueous extract of cissus populnea (guill. and per) stem bark.in vivo clinical trials involving the administration of crude extracts of cissus populnea to male subjects (normospermic, oligospermic, and azoopermic) in a 72-day study revealed that continuous exposure of the subjects to the extracts over this period did not significantly (p < or = 0.05) alter sperm count, morphology, motility, or volume. antimicrobial screening of the extract against some selected microbial isolates secondarily implicated in male infertility revealed total inactivity against ...200617370009
germa-gamma-lactones as novel inhibitors of bacterial urease activity.organogermanium compounds have been used as pharmacological agents. however, very few reports are available on the synthesis and antibacterial activities of lactones containing organogermaniums. the purpose of the present investigation was to determine the effects of different lactone-substituted organogermaniums on bacterial growth and their urease activity. we report synthesis of 12 germa-gamma-lactones (gel) and their antimicrobial activities against several bacterial pathogens. antibacterial ...200717367756
microfluidic chip analysis of outer membrane proteins responsible for serological cross-reaction between three gram-negative bacteria: proteus morganii o34, escherichia coli o111 and salmonella adelaide o35.bacterial strains have complex and individual antigenic structure, which provides basis for their serological identification. however, serological cross-reaction may occur when antibodies against a certain strain recognize other strains too. the molecular basis of this phenomenon is the expression of similar or identical antigenic epitopes on the surface of different bacterial cells. such cross-reactions might harden the serological diagnosis of pathogenic bacteria. but it can be also advantageo ...200717362972
[ocular manifestations in proteus syndrome].case report: congenital disfiguring malformations are rare and usually have a multifactorial aetiology. here we report on the ocular manifestations seen in a patient with proteus syndrome. the retina showed retinal dysgenesia, retinal pigmentary abnormalities and optic nerve hypoplasia. other abnormalities included strabismus and high myopia. discussion: proteus syndrome is a complex hamartomatous disorder defined by local overgrowth, subcutaneous tumours and various bone, cutaneous and/or vascu ...200717357896
pericardial tamponade masquerading as septic shock.a 53-year-old man with steroid dependent rheumatoid arthritis presented with fever and serous articular drainage. oral antibiotics were initially prescribed. subsequent hemodynamic instability was attributed to septic shock. further evaluation revealed a pericardial effusion with tamponade. pericardiocentesis of purulent fluid promptly corrected the hypotension. proteus mirabilis was later isolated from both the infected joint and the pericardial fluid. this is the first report of combined prote ...200717356998
does water activity rule p. mirabilis periodic swarming? ii. viscoelasticity and water balance during swarming.following the analysis of the biochemical and functional properties of the p. mirabilis extra cellular matrix performed in the first part of this study, the viscoelasticity of an actively growing colony was investigated in relation to water activity. the results demonstrate that the p. mirabilis colony exhibits a marked viscoelastic character likely due to both cell rafts and exoproduct h-bond networks. besides, the water loss by evaporation during migration has been measured, whereas the experi ...200717355121
does water activity rule p. mirabilis periodic swarming? i. biochemical and functional properties of the extracellular matrix.the dynamics of bacterial colonies is complex in nature because it correlates the behavior of numerous individual cells in space and time and is characterized by emergent properties such as virulence or antibiotics resistance. because there is no clear-cut evidence that periodic swarming of p. mirabilis colonies is ruled by chemical triggers responsible for cell-to-cell signaling in most of the biofilms, we propose that the observed periodicity relies on the colony's global properties. hence, th ...200717355120
characteristics of motive force derived from trajectory analysis of amoeba proteus.we used a monochromatic charge-coupled-device camera to observe the migration behavior of amoeba proteus every 5 s over a time course of 10000 s in order to investigate the characteristics of its centroid movement (cell velocity) over the long term. fourier transformation of the time series of the cell velocity revealed that its power spectrum exhibits a lorentz type profile with a relaxation time of a few hundred seconds. moreover, some sharp peaks were found in the power spectrum, where the ra ...200717351734
surveillance of extended-spectrum beta-lactamase-producing bacteria and routine use of contact isolation: experience from a three-year period.the usefulness and applicability of isolation precautions were questioned for extended-spectrum beta-lactamase (esbl)-producing strains of enterobacteriaceae in the endemic setting. we performed a surveillance programme for esbl-positive organisms and the infection control management of patients colonized or infected with these organisms. between 1 january 2002 and 31 december 2004, a total of 147 cases of esbl-producing strains of escherichia coli, klebsiella pneumoniae and proteus mirabilis fr ...200717350720
surveillance of antimicrobial susceptibility of urinary pathogens in a tertiary care hospital. 200717342301
antibacterial activities of emblica officinalis and coriandrum sativum against gram negative urinary pathogens.present investigation is focused on antibacterial potential of aqueous infusions and aqueous decoctions of emblica officinalis (amla) and coriandrum sativum (coriander) against 345 bacterial isolates belonging to 6 different genera of gram negative bacterial population isolated from urine specimens by employing well diffusion technique. aqueous infusion and decoction of emblica officinalis exhibited potent antibacterial activity against escherichia coli (270), klebsiella pneumoniae (51), k. ozae ...200717337425
mild and delayed-onset proteus syndrome. 200717337412
linear cowden nevus: a new distinct epidermal nevus.within the group of epidermal nevi, a so far nameless disorder is described under the term "linear cowden nevus". this non-organoid epidermal nevus is caused by loss of heterozygosity, occurring at an early developmental stage in an embryo with a germline pten mutation, giving rise to cowden disease. hence, linear cowden nevus can be categorized as a characteristic feature of type 2 segmental cowden disease. until now, several authors had mistaken this epidermal nevus as a manifestation of prote ...200717337396
[incidence and clinical characteristics of symptomatic urinary infections in a geriatric hospital].objectives and settings: the authors had for aim to study the incidence of symptomatic urinary infections (suti) in elderly patients, to describe their clinical and microbiologic characteristics and first-line treatment in a geriatric hospital with 902 beds: 124 in acute care (acf), 293 in rehabilitation and intermediate-care (ricf), and 485 in long-term-care-facilities (ltcf).200717337143
amoeba proteus displays a walking form of locomotion.this report deals with observations on the directional locomotion of amoeba before and after fixation and scanning electron microscopy. the study was aimed at visualization of the stepwise events of directional movements. after the analysis of the data it is proposed that the amoeba undergoes a sequence of movement events that can be defined as a walking form of locomotion.200717336550
digestive tract microbiota in healthy volunteers.the aim of this study was to standardize the methods of sample collection of mucus from the digestive tract and to determine the microbiota in healthy volunteers from brazil, collecting samples from the mouth, esophagus, stomach, duodenum, jejunum, ileum, colon, and rectum.200717334549
microbiology of diabetic foot infections in a teaching hospital in malaysia: a retrospective study of 194 cases.diabetes mellitus is a progressive disease with chronic complications. foot infections are a major complication of diabetes and eventually lead to development of gangrene and lower extremity amputation. the microbiological characteristics of diabetic foot infections have not been extensively studied in malaysia. this study investigated the microbiology of diabetic foot infections and their resistance to antibiotics in patients with diabetic foot infections treated at university of malaya medical ...200717332905
interspecies spread of ctx-m-32 extended-spectrum beta-lactamase and the role of the insertion sequence is1 in down-regulating bla ctx-m gene expression.to characterize the extended-spectrum beta-lactamases (esbls) as well as their genetic environment in different isolates of enterobacteriaceae from a patient with repeated urinary tract infections.200717332005
perinephric abscess secondary to a staghorn calculus presenting as a subcutaneous abscess.perinephric abscesses often present with flank pain and signs of sepsis, and are known to discharge to the skin. we report a case of a young patient presenting with a 48-hour history of painful swelling in her right renal angle following a urinary tract infection and no overt signs or symptoms of sepsis. plain abdominal films showed a perinephric abscess secondary to a staghorn calculus in the upper pole of the right kidney. on incision and drainage, 700 ml of pus was drained freely. the patient ...200617324312
multifocal proteus mirabilis osteomyelitis requiring bilateral amputation in an hiv-positive patient.we present a rare case of multifocal proteus mirabilis osteomyelitis in an hiv-positive patient. despite the patient's good immune status as assessed by her cd4 cell count and the aggressive treatment, she eventually underwent bilateral above-knee amputations to eradicate the infection. multifocal proteus mirabilis osteomyelitis can have an unpredictable clinical course with a severe outcome in hiv-positive patients.200717322447
regulation of flhdc expression in proteus mirabilis.transposon insertions located 325 and 740 base pairs upstream of the transcriptional start site of the flhdc operon resulted in cells that initiated swarming 1.5h earlier than wild-type and exhibited a 2-2.5-fold greater swarming velocity. these mutants also failed to consolidate (de-differentiate) normally and did not form the characteristic bulls-eye pattern of concentric swarming rings on solid media. the analysis of one mutant (ss-p) with an insertion at -325 revealed that the levels of flhd ...200717320355
regulation of ribosomal rna synthesis in cold-shocked e. coli. 197317319073
effect of ovotransferrin, protamine sulfate and edta combination on biofilm formation by catheter-associated bacteria.to determine the effect of a composition comprising ovotransferrin (ot), protamine sulfate (ps) and ethylenediaminetetraacetic acid (edta) on biofilm formation by catheter-associated bacteria.200717309621
antibacterial activity of snake, scorpion and bee venoms: a comparison with purified venom phospholipase a2 enzymes.venoms of snakes, scorpions, bees and purified venom phospholipase a(2) (pla(2)) enzymes were examined to evaluate the antibacterial activity of purified venom enzymes as compared with that of the crude venoms.200717309613
evaluating antibiotics for use in medicine using a poloxamer biofilm model.wound infections, due to biofilms, are a constant problem because of their recalcitrant nature towards antibiotics. appropriate antibiotic selection for the treatment of these biofilm infections is important. the traditional in vitro disc diffusion method for antibiotic selection uses bacterial cultures grown on agar plates. however, the form of bacterial growth on agar is not representative of how bacteria grow in wounds and other tissue sites as here bacteria grow naturally in a biofilm. the a ...200717302978
bacteriological quality of some pharmaceutical products marketed by drug vendors in uyo, nigeria.bacteriological quality of some pharmaceutical products purchased from open markets, buses and drug stores in uyo metropolis was studied in order to determine the level of contamination of the drugs. the drug samples examined were tetracycline capsules, paracetamol tablets, ampicillin capsules, chloroquine tablets, chloroquine syrup, chloroquine injections, flagyl tablets and chloramphenicol tablets. the bacterial count ranged from 2.3x10(4) cfu/g to 4.4x10(4) cfu/g for the 16 samples of ampicil ...200417298130
[pyrazinamidase activity of bacteria from enterobacteriaceae family as characteristic for taxonomy].pyrazinamidase activity in 330 strains of bacteria from enterobacteriaceae family (14 genus, 27 species) has been assessed. pyrazinamidase activity detected in species from following genuses: citrobacter, escherichia, klebsiella, kluyvera, morganella, providencia, raourtella, salmonella, shigella, and also in proteus mirabilis, and nonpathogenic serovars of yersinia enterocolitica, y. frederiksenii. pirasinamidase was absent in serratia (s. marcescens, s. liguefaciens), hafnia alvei, p. vulgaris ...200617297889
[antagonistic effect of bacteriocinogenic lactobacillus acidophilus on klebsiella pneumoniae, citrobacter freundii and proteus mirabilis cells].data of the ultrastructural cellular changes of conditionally pathogenic enterobacteria, including k. pneumoniae, c. freundii and p. mirabilis cells impacts to bacteriocin-producing l. acidophilus are presented. enterobacteria in response to the bacteriocinogenic effect of lactobacilli are manifestated by expressive destructions of sensitive to pore formation bacteriocin cells. various morphological types of enterobacteria cells with increase of involution, lysing and resting forms are revealed. ...200617297872
calcium sulphate delivery system with tobramycin for the treatment of chronic calcaneal osteomyelitis.the case of a 24-year-old woman with pseudomonas aeruginosa and proteus mirabilis chronic calcaneal osteomyelitis is presented. extensive debridement of the necrotic bone and application of tobramycin-loaded polymethylmethacrylate beads was performed and ciprofloxacin was given post-operatively. three months later, laboratory tests, including complete blood cell count, erythrocyte sedimentation rate and c-reactive protein, were normal. at this time, extensive surgical debridement and filling of ...200617295005
identification and quantitation of usnic acid from the lichen usnea species of anatolia and antimicrobial activity.six species of lichens, such as usnea florida, usnea barbata, usnea longissima, usnea rigida, usnea hirta and usnea subflorida, were collected from different areas of anatolia (district of antalya, karabük, qankiri, giresun and trabzon) in turkey. their usnic acid amounts in acetone extracts were determined by hplc. in addition, antimicrobial activities of these extracts were determined against escherichia coli (atcc 35218), enterococcus faecalis (rskk 508), proteus mirabilis (pasteur ens. 235), ...200617294685
potential integration sites of the salmonella genomic island 1 in proteus mirabilis and other bacteria. 200717293370
detection of extended-spectrum beta-lactamases among enterobacteriaceae by use of semiautomated microbiology systems and manual detection procedures.three commercially available microbiology identification and susceptibility testing systems were compared with regard to their ability to detect extended-spectrum beta-lactamase (esbl) production in enterobacteriaceae, i.e., the phoenix automated microbiology system (bd diagnostic systems, sparks, md), the vitek 2 system (biomérieux, marcy l'etoile, france), and the microscan walkaway-96 system (dade behring, inc., west sacramento, ca), using routine testing panels. one hundred fifty putative es ...200717287329
in vivo evaluation of teicoplanin- and calcium sulfate-loaded pmma bone cement in preventing implant-related osteomyelitis in rats.the objective of this study was to evaluate the efficacy of teicoplanin- and calcium sulphate-loaded polymethylmethacrylate (pmma) bone cements in preventing experimental implant-related osteomyelitis in rats. four groups of antibiotic-loaded rods were prepared and were implanted into the lateral condylus of the rat femur after inoculation of staphylococcus aureus. the effectiveness of these were assessed microbiologically, radiographically, and histopathologically. radiographic evaluation revea ...200617267341
[bacteriological evaluation in chronic otitis media].in chronic otitis media bacterial infection is often a cause of exacerbation in the clinical course and failure in treatment. the aim of the study was to investigate the incidence and profile of the aerobic bacterial flora in chronic otitis media and to determine the drug susceptibility of selected isolated bacteria.200617263251
[community-acquired urinary tract infections in 15 to 65 years old female patients in france. susceptibility of e. coli according to history: aforcopi-bio network 2003].a multicenter study was implemented in order to determine the distribution and antibiotic susceptibility patterns of strains isolated from 15 to 65 year old female patients with community-acquired urinary tract infections.200717258415
synthesis of pseudopeptides based l-tryptophan as a potential antimicrobial agent.four compounds named l-btrppa, l-trp-o-pa, l-trp-m-pa and l-trp-p-pa, pseudopeptides constructed from pyridine and tryptophan units, were synthesized and tested against the gram-positive, gram-negative strains of bacteria and human pathogenic fungi. l-trp-o-pa proved to be a broad-spectrum antimicrobial agent, showing a significant inhibition of the growth of gram-positive bacteria (staphylococcus aureus, methicillin-resistant s. aureus, bacillus subtilis, micrococcus luteus), and pathogenic fun ...200717257839
emerging bacterial pathogens: escherichia coli, enterobacter aerogenes and proteus mirabilis clinical isolates harbouring the same transferable plasmid coding for metallo-beta-lactamase vim-1 in greece. 200717255145
structure of proteus mirabilis biofilms grown in artificial urine and standard laboratory media.proteus mirabilis is a urinary pathogen that can differentiate from a swimmer cell into a swarmer cell morphotype and can form biofilms on the surfaces of urinary catheters. these biofilms block these catheters due to crystals trapped within these structures. the effect of encrustation on biofilm formation and structure has not been studied using confocal scanning laser microscopy (cslm). therefore, a comparison of biofilm structure in artificial urine (au) and laboratory media was undertaken. w ...200717250761
more than just a bump: the hamartoma syndromes.the hamartoma syndromes detailed in this review are just a few examples of the many genodermatoses now known to be associated with uncontrolled tumor proliferation secondary to mutations in tumor suppressor genes. knowledge gained through the study of these syndromes has not only improved our understanding of patients afflicted with such conditions, but has also led to significant insight into the important role tumor suppressor genes play in preventing tumor formation and in carcinogenesis. as ...200617249301
studies on reproduction in amoeba proteus. 192417246033
the first structure of a cold-active catalase from vibrio salmonicida at 1.96 a reveals structural aspects of cold adaptation.the cold-adapted catalase from the fish-pathogenic bacterium vibrio salmonicida (vsc) has recently been characterized and shown to be two times more catalytically efficient compared with catalase from the mesophilic human pathogen proteus mirabilis [pmc; lorentzen et al. (2006), extremophiles, 10, 427-440]. vsc is also less temperature-stable, with a half-life of 5 min at 333 k compared with 50 min for pmc. this was the background for solving the crystal structure of the cold-adapted vsc to 1.96 ...200717242507
spectroscopic description of an unusual protonated ferryl species in the catalase from proteus mirabilis and density functional theory calculations on related models. consequences for the ferryl protonation state in catalase, peroxidase and chloroperoxidase.the catalase from proteus mirabilis peroxide-resistant bacteria is one of the most efficient heme-containing catalases. it forms a relatively stable compound ii. we were able to prepare samples of compound ii from p. mirabilis catalase enriched in (57)fe and to study them by spectroscopic methods. two different forms of compound ii, namely, low-ph compound ii (lph ii) and high-ph compound ii (hph ii), have been characterized by mössbauer, extended x-ray absorption fine structure (exafs) and uv-v ...200717237942
[murine typhus - rare cause of fever return from egypt].authors present a case report of 42-year male who spent 14 days in august of 2003 in egyptian seaside summer town hurghada and later he was admitted to the infectious disease department prague with the fever lasting 4 days. his symptoms were as follows: strong headache and dry cough. on the 7th and 8th day appeared transient maculopapular rash, laboratory test revealed a slightly elevated c reactive protein and elevation of amino transferases up to 5 times higher than range values, chest x-ray s ...200617230380
the xaxab genes encoding a new apoptotic toxin from the insect pathogen xenorhabdus nematophila are present in plant and human pathogens.xenorhabdus nematophila, a member of the enterobacteriaceae, kills many species of insects by strongly depressing the immune system and colonizing the entire body. a peptide cytotoxin has been purified from x. nematophila broth growth, and the cytolytic effect on insect immunocytes and hemolytic effect on mammalian red blood cells of this toxin have been described (ribeiro, c., vignes, m., and brehélin, m. (2003) j. biol. chem. 278, 3030-3039). we show here that this toxin, xenorhabdus alpha-xen ...200717229739
role of ser11 in the stabilization of the structure of ochrobactrum anthropi glutathione transferase.gsts (glutathione transferases) are a multifunctional group of enzymes, widely distributed and involved in cellular detoxification processes. in the xenobiotic-degrading bacterium ochrobactrum anthropi, gst is overexpressed in the presence of toxic concentrations of aromatic compounds such as 4-chlorophenol and atrazine. we have determined the crystal structure of the gst from o. anthropi (oagst) in complex with gsh. like other bacterial gsts, oagst belongs to the beta class and shows a similar ...200717223798
spontaneous bacterial peritonitis causing serratia marcescens and proteus mirabilis ventriculoperitoneal shunt infection. case report.the authors report their experience treating a polymicrobial ventriculoperitoneal (vp) shunt infection in a developmentally delayed 21-year-old woman. cerebrospinal fluid (csf) cultures grew serratia marcescens and proteus mirabilis. on admission and throughout her hospitalization, results of physical examination of her abdomen were normal, and radiographic studies showed no evidence of bowel perforation or pseudocyst formation. contrast-enhanced computed tomography of the abdomen revealed a sma ...200617219841
ureaplasma urealyticum as a causative organism of urinary tract infection stones.ureaplasma urealyticum is a fastidious organism which is not recovered by conventional bacterial cultures techniques, but special cultures are required for its isolation and identification. as it is a urease-producing organism, it is considered a risk factor for the formation of struvite calculi in the urinary tract. a total of 30 patients with urinary infection stones (19 of them with the 1st formation and 11 with recurrent stone formation) were included in the study. both bladder urine specime ...199617217015
screening of some food poisoning bacteria in sausage and hamburger meat.microbial investigation of 30 samples of sausage meat and 30 samples of hamburger meat, freshly prepared, were collected randomly from different markets in alexandria city, to determine the bacteriological status of these products. the average counts/gm of total bacteria, total coliforms and fecal coliform in sausage meat were 1.33 x 10(7), 9.16 x 10(5) and 1.11 x 10(3) respectively, and in hamburger samples were 8.47 x 10(5), 2.63 x 10(3) and 1.35 x 10(3) respectively. shigella, escherichia col ...199617217001
rhomboid protease aara mediates quorum-sensing in providencia stuartii by activating tata of the twin-arginine translocase.the providencia stuartii aara protein is a member of the rhomboid family of intramembrane serine proteases and is required for the production of an unknown quorum-sensing molecule. in a screen to identify rhomboid-encoding genes from proteus mirabilis, tata was identified as a multicopy suppressor and restored extracellular signal production as well as complementing all other phenotypes of a prov. stuartii aara mutant. tata is a component of the twin-arginine translocase (tat) protein secretion ...200717215357
skull base osteomyelitis presenting as villaret's syndrome.this report documents a 47-year-old male who developed acute deficits of the ix, x, xi, xii cranial nerves and horner's symptoms, consistent with villaret's syndrome. neuroimaging studies demonstrated an osteolytic lesion in the skull base involving the clivus and jugular foramen. the patient recovered after the antibiotic treatment for proteus mirabilis infection. we suggest that villaret's syndrome can be a rare presentation of skull base osteomyelitis.200617214089
bacterial isolates of blood cultures in patients with suspected septicaemia in ilorin, nigeria.periodic bacteriologic surveillance of blood cultures is a necessity. to determine currently prevalent bacterial pathogens of blood cultures in patients with suspected septicaemia in ilorin. nigeria. three thousand and fifty-seven patients from all age and sex groups with clinical suspicion of septicaemia underwent bacteriologic screening of their blood specimen over a 13 month period starting from january. 2003. twenty point three percent were positive for bacterial growth. an incidence of 41.7 ...200617209308
rheumatoid arthritis is linked to proteus--the evidence.rheumatoid arthritis (ra) is a chronic inflammatory arthritic and potentially disabling condition, mainly affecting women of middle age and having characteristic clinical features. various microbial agents were implicated in the causation of ra. extensive literature based on the results of various genetic, microbiological, molecular, and immunological studies carried out by independent research groups supports the role of proteus mirabilis bacteria in the etiopathogenesis of ra. new diagnostic m ...200717206398
[short communication: prevalence of extended spectrum beta-lactamases in gram negative rods: data of 2001-2004 period].this study was undertaken to determine the prevalence of extended spectrum beta-lactamase (esbl) production by gram negative rods (gnrs) isolated from various clinical specimens (3.240 urine, 336 pus, 277 feces, 83 blood, 38 sputum) sent to our hospital laboratory, between 2001-2004. of isolated bacteria 71.4% were identified as escherichia coli, 11.1% were klebsiella spp, 4.2% were salmonella spp, 3.7% were pseudomonas spp, 3.5% were proteus spp, 2.9% were shigella spp, 2.3% were enterobacter s ...200617205693
[pseudomonas aeruginosa colonisation in bronchiectatic patients and clinical reflections].bronchiectasis is characterized with irreversible dilatation according to destruction of epithelium, elastic and muscular layer. most important cause of bronchiectasis is chronic bacterial infections. pseudomonas aeruginosa colonisation is frequently seen in bronchiectatic patients. we aimed to find out p. aeruginosa colonisation frequency and clinical, radiological and spirometric reflections due to colonisation. we analysed 83 cases retrospectively. mean age was 58.2 and 54.2% of them were fem ...200617203422
comparison of three techniques for the diagnosis of urinary tract infections in dogs with urolithiasis.to identify an appropriate sampling technique(s) to accurately detect the bacteria causing urinary tract infections in dogs with urolithiasis.200617201824
accelerated detection of extended-spectrum beta-lactamases in clinical isolates of enterobacteriaceae.a prospective study is carried out to evaluate the performance of a protocol for the accelerated detection of extended-spectrum beta-lactamases (esbls) in clinical isolates of escherichia coli, klebsiella pneumoniae and other gram-negative bacteria. a modified double-disc test (mddt) is incorporated in a gram-negative template for routine susceptibility testing. the mddt identified accurately esbls in all isolates subsequently confirmed as esbl-producers by the standard clinical laboratory stand ...200617201201
pathogenic colonization of the stomach in enterally fed elderly patients: comparing percutaneous endoscopic gastrostomy with nasogastric tube.to compare the gastric juice microbiota of older people fed through a percutaneous endoscopic gastrostomy tube (peg) with that of those fed through a nasogastric tube (ngt).200617198497
[using antibiotics in urinary tract infection in a first level of attention health care unit in bogotá, colombia].describing using antibiotics for urinary tract infection in a first level of attention health care unit.200617191601
bacteriology of chronic discharging ears in port harcourt, nigeria.the objective of the study was to isolate and identify aerobic bacteria in chronic discharging ears and determine their antibiotic susceptibilities, which is essential for reasonable empiric treatment.200617191422
comparison of pharmacodynamic and pharmacokinetic indices of efficacy for 5 fluoroquinolones toward pathogens of dogs and cats.fluoroquinolones are often used interchangeably in dogs and cats.200617186841
both sulfate-reducing bacteria and enterobacteriaceae take part in marine biocorrosion of carbon steel.in order to evaluate the part played in biocorrosion by microbial groups other than sulfate-reducing bacteria (srb), we characterized the phylogenetic diversity of a corrosive marine biofilm attached to a harbour pile structure as well as to carbon steel surfaces (coupons) immersed in seawater for increasing time periods (1 and 8 months). we thus experimentally checked corroding abilities of defined species mixtures.200717184331
helicobacter pylori: an underestimated factor in acute anterior uveitis and spondyloarthropathies?acute anterior uveitis (aau) is the most common form of intraocular inflammation, but its aetiology is still unclear. fifty percent of aau patients are hla-b27-positive, and half of these also have spondyloarthropathies (spa). numerous serological studies have shown elevated levels of serum antibodies to various gram-negative bacteria in hla-b27-positive aau and spa patients. antigenic similarities between these bacteria and host components (hla-b27) have already been shown. still, the mechanism ...200717183194
structure of the o-polysaccharide and serological cross-reactivity of the lipopolysaccharide of providencia alcalifaciens o32 containing n-acetylisomuramic acid.the o-polysaccharide was obtained by mild acid degradation of the lipopolysaccharide of providencia alcalifaciens o32 and studied by sugar and methylation analyses, solvolysis with triflic acid, 1h and 13c nmr spectroscopy, including two-dimensional 1h,1h cosy, tocsy, roesy, h-detected 1h,13c hsqc and hmbc experiments. it was found that the polysaccharide has a branched tetrasaccharide repeating unit containing 2-acetamido-3-o-[(s)-1-carboxyethyl]-2-deoxy-d-glucose (d-glcnac3slac, n-acetylisomur ...200717182016
proteus bacteriuria is associated with significant morbidity in spinal cord injury.retrospective chart review.200717179975
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