Publications

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on the anaesthetic properties of the lycoperdon proteus, or common puff-ball. 185320740850
xv. the rôle of the bacillus proteus vulgaris in surgery. 190217861144
viii. the identity of proteus infection and hospital gangrene: a case of mixed infection with aerogenes capsulatus and proteus vulgaris. 190217861211
the cultivation of amoebae in pure culture upon autolyzed tissues.since the purpose of this paper is to record the cultivation of amoebae upon autolyzed tissue without bacterial association, the morphological characteristics, life cycle, means of differentiating species, and pathogenicity of the protozoa have been omitted. these subjects will be considered in later publications. the result of this study proves that some species of amoebae from liver abscesses and the human intestine can be cultivated upon various autolyzed tissues of man and some of the lower ...191319867701
a study of the pathogenic properties of bacillus proteus.some strains of bacillus proteus obtained from human lesions are pathogenic for rabbits, rats, and guinea pigs. there is good evidence that these strains are also pathogenic for man. all cultures obtained from sources other than human infections were non-pathogenic for the laboratory animals. a non-pathogenic culture may be made pathogenic by the use of aggressins or by inoculation into the anterior chamber of the eye. proteus cultures lose their virulence rapidly when grown on artificial media. ...191519867897
concerning the species amoeligba proteus. 191617795980
a systematic study of the proteus group of bacteria. 191916558845
chilomastix mesnili and a method for its culture.1. cases of flagellate infection of man by chilomastix mesnili have been reported from nearly every locality in the world. they are fairly abundant in the united states and are often confused with cases of infection by trichomonas intestinalis. 2. the shape of chilomastix is pyriform. the body contains the following structures: nucleus, centrosome, primary, secondary, and tertiary blepharoplasts, parabasal, parastyle, peristomal fiber, ventral cytostome, cytostomal flagellum, three anterior flag ...192119868485
studies on bacterial nutrition : i. growth of bacillus influenzae in hemoglobin-free media.from the data presented in the foregoing experiments it is evident that bacillus influenzae will grow in a fluid medium consisting of plain broth to which have been added small amounts of emulsions or extracts of mucoid bacilli or of bacillus proteus. the bacterial extracts may be made by simple boiling of the bacillary emulsions in broth or saline solution and centrifuging out the bacterial bodies; they may be filtered without losing their growth-inducing property. cultures of bacillus influenz ...192119868534
experimental studies on the etiology of typhus fever : i. concurrent infections during the course of experimental typhus fever in guinea pigs.the work reported in this paper relates to the bacteria which can be cultivated from the blood and spleen of guinea pigs at different stages of infection with the virus of typhus fever. the studies show that during the period of incubation and before the onset of fever no ordinary bacteria appear in the cultures, while on the 1st day of the febrile reaction different bacteria were found in 6 of 26 guinea pigs cultured; on the 2nd day, in 10 of 16; on the 3rd day, in 3 of 4; and on the 4th day in ...192119868575
charles proteus steinmetz. 192317770636
studies on reproduction in amoeba proteus. 192417246033
a fatal infection with an organism of the proteus group. 192419972606
blood sugar studies : i. rapid alterations in the blood sugar level of rabbits as result of intravenous injections of killed bacteria of various types.a rapid rise in the blood sugar level of rabbits was produced by intravenous injections of killed bacillus proteus, bacillus coli, and bacillus paratyphosus b, which returned to nearly the previous level in a few hours time. a less pronounced rise in blood sugar was produced by killed bacillus paratyphosus a and bacillus enteritidis.192519869033
micrurgical studies in cell physiology : i. the action of the chlorides of na, k, ca, and mg on the protoplasm of amoeba proteus.by means of micro-dissection and injection amoeba proteus was treated with the chlorides of na, k, ca, and mg alone, in combination, and with variations of ph. i. the plasmalemma. 1. nacl weakens and disrupts the surface membrane of the ameba. tearing the membrane accelerates the disruption which spreads rapidly from the site of the tear. kcl has no disruptive effect on the membrane but renders it adhesive. 2. mgcl(2) and cacl(2) have no appreciable effect on the integrity of the surface membran ...192619872206
micrurgical studies in cell physiology : ii. the action of the chlorides of lead, mercury, copper, iron, and aluminum on the protoplasm of amoeba proteus.i. plasmalemma. 1. the order of toxicity of the salts used in these experiments on the surface membrane of a cell, taking as a criterion viability of amebae immersed in solutions for 1 day, is hgcl(2), fecl(3)> alcl(3)> cucl(2)> pbcl(2)> fecl(2). using viability for 5 days as a criterion, the order of toxicity is pbcl(2)> cucl(2)> hgcl(2)> alcl(3)> fecl(3)> fecl(2). 2. the rate of toxicity is in the order fecl(3)> hgcl(2)> alcl(3)> fecl(2)> cucl(2)> pbcl(2). 3. the ability of amebae to recover f ...192619872315
the contractile vacuole granules in amoeba proteus. 192617739269
the effect of hydrogen-ion concentration on locomotion and other life-processes in amoeba proteus. 192616587084
proteus henricensis nov. spec. 192717752626
use of a glucose bismuth sulphite iron medium for the isolation of b. typhosus and b. proteus. 192720474937
on proteus pseudovaleriae and its occurrence in man. 192720474947
intracellular oxidation-reduction studies : i. reduction potentials of amoeba dubia by micro injection of indicators.twenty-five oxidation-reduction indicators were injected in oxidized or reduced form into amoeba dubia and amoeba proteus under controlled conditions of oxygen access. (1) under anaerobiosis the ameba was able to reduce completely all the reversible oxidation-reduction indicators down to and including indigo disulfonate. (2) under anaerobiosis the ameba was unable to reoxidize six of the most easily oxidizable indicators. (3) under aerobiosis the ameba was able to reduce completely all the indic ...192819872422
on precipitable substances derived from bacillus typhosus and bacillus paratyphosus b.attempts to confirm certain statements that ether-soluble specific substances can be obtained from b. typhosus have lead to negative results. two serologically active protein substances and another that was non-protein have been separated from b. typhosus. the first two are not resistant to tryptic digestion or to treatment with alkaline hypochlorite solution whereas the third resists both. one of the proteins could be extracted with 75 per cent alcohol. specific precipitable substances reacting ...192819869396
some conditions affecting the production of gelatinase by proteus bacteria. 192816559306
action of hydrogen sulfide on the protoplasm of amoeba proteus. 192917773751
measurements of the metabolism of two protozoans.1. the respiration of amoeba proteus was measured. 10 c. mm. of cells were found to use about 1.6 mm.(3) of oxygen per hour at 20 degrees c. the respiratory quotient was found to be nearly unity. 2. no anaerobic metabolism was found for amoeba. 3. the respiration of blepharisma was found to be from 3 to 7 mm.(3) oxygen per hour for 10 mm.(3) cells. the respiratory quotient was about 1. 4. blepharisma was shown to have a definite anaerobic metabolism. 80 mm.(3) cells caused the evolution of 12.5 ...192919872514
a bacillus proteus brain abscess. 192921433446
typhus-like fevers of unknown aetiology, with special reference to the malay states.typhus exanthematicus, rocky mountain fever, and the tsutsugamushi disease have been classified in the "typhus group" by megaw, as louse-typhus, tick-typhus, and mite-typhus. he has added a fourth-class, comprising typhus-like fevers, with unknown vectors. it is the diseases of this class with which this paper is concerned.endemic typhus (brill's disease) is very closely related to typhus fever; the weil-felix reaction is positive, typhus-like vascular lesions are present, and there is cross-imm ...193019987538
typhus-like fevers of unknown ætiology, with special reference to the malay states.typhus exanthematicus, rocky mountain fever, and the tsutsugamushi disease have been classified in the "typhus group" by megaw, as louse-typhus, tick-typhus, and mite-typhus. he has added a fourth-class, comprising typhus-like fevers, with unknown vectors. it is the diseases of this class with which this paper is concerned.endemic typhus (brill's disease) is very closely related to typhus fever; the weil-felix reaction is positive, typhus-like vascular lesions are present, and there is cross-imm ...193020911935
a serological study of the polysaccharides of meningococcus, b. anthracis, b. proteus, b. subtilis and b. mesentericus.1. the meningococcus polysaccharide reacts with a broad precipitable carbohydrate antibody in common with those of b. anthracis, b. subtilis, b. proteus and b. mesentericus. 2. the anthrax and proteus polysaccharides are specific in the higher dilutions of serum. 3. antianthrax serum contains two different polysaccharide precipitable antibodies, one specific and the other non-specific. 4. agglutinins have no relation to the carbohydrate precipitable substance, specific or non-specific. 5. an imm ...193119869953
carbohydrates adsorbed on colloids as antigens.evidence is here given that polysaccharides can be rendered antigenic by haptogenic adsorption upon a colloid carrier. the polysaccharides studied were those of b. anthracis, the meningococcus, streptococcus viridans (bargen), b. proteus, s. morgani, b. dysenteriae, both the shiga and hiss types, and the pneumococci. with the polysaccharide of type iii pneumococci, we have been unable in 6 weeks to produce any detectable protective antibodies, but we were able to produce anticarbohydrate antibod ...193219869994
studies on typhus fever : ix. on the serum reactions of mexican and european typhus rickettsia.1. the blood of guinea pigs convalescent from old world and new world typhus infection develops agglutinating properties for the tunica and rat rickettsiae of the new world diseases and for the louse rickettsia of the old world disease. 2. the two microorganisms are closely related, though probably not identical. 3. human convalescents of both varieties of typhus develop agglutinins for both types of rickettsiae. such rickettsia-agglutinating properties are parallel with the weil-felix reaction ...193219870078
pleomorphism of proteus vulgaris determined by sodium chloride content of culture medium, and simulating stages in a life cycle. 193220475136
studies on typhus fever : xi. a report on the properties of the serum of a horse immunized with killed formalinized rickettsia.the experiments recorded above demonstrate that the systematic treatment of a horse with formalin- and phenol-killed rickettsiae obtained from the mexican virus by our x-ray rat technique induces the development of properties in the horse's serum which may be described as follows: 1. an original agglutinating potency for proteus x-19 (weil-felix reaction) not exceeding dilutions of 1-40 was enhanced to a potency of 1-160 and, feebly, 1-320. 2. the horse's serum, after immunization, exerts distin ...193319870138
the antigenic relationship between proteus x-19 and typhus rickettsiae : a study of the weil-felix reaction.1. the absorption of typhus sera (human or antityphus horse serum) with proteus x-19 removes only the proteus agglutinins, leaving the rickettsia agglutinins intact. 2. the absorption of typhus sera with mexican rickettsiae removes the agglutinins for both the rickettsia and proteus x-19. 3. while normal or formalinized rickettsiae are not agglutinated by anti-proteus serum, these organisms-when formalinized and heated at 75 degrees c.-become agglutinable by such serum. 4. the absorption of anti ...193319870181
on the rate of oxygen consumption by fertilized and unfertilized eggs : v. comparisons and interpretation.1. the rate of oxygen consumption by eggs may not merely undergo no change at fertilization, as in the case of the starfish, but it decreases to about half in chaetopterus and in cumingia. 2. the absolute rate of oxygen consumption in mm.(3) o(2) per hour per 10 mm.(3) eggs differs widely in several species of unfertilized eggs. it is very low in the sea urchin, intermediary in nereis, and high in chaetopterus and cumingia. the range for these eggs is approximately 0.4 to 3.1 mm.(3) o(2) per hou ...193319872719
bacillus proteus septicemia. 193318742542
the anaerobic decomposition of l-cystine by washed cells of proteus vulgaris. 193316745154
the pleo-antigenicity of a variant of proteus x19. 193416559764
charles proteus steinmetz and the american institute of electrical engineers. 193417745747
the observation of mitosis in the living cell in amoeba proteus. 193417747194
pleo-antigenicity of proteus x19. 193418014082
the antigenic relationship between proteus x-19 and typhus rickettsia : ii. a study of the common antigenic factor.a soluble specific substance was isolated from mexican typhus rickettsia which gave, with proteus x-19 antiserum and typhus human serum, the same precipitation reactions as the polysaccharides extracted from b. proteus ox-19. the soluble specific substance extracted from rickettsia and proteus ox-19 is likely to be of a polysaccharide nature owing to the strong molisch reactions obtained with such extracts, the heat stability and the negative protein reactions (biuret). since, however, it still ...193419870282
the reputed antigenic relationship between organisms of the brucella group on the one hand, and of the pasteurella, pfeifferella, and proteus groups on the other. 193420475241
the antigenic relationship between bacillus proteus x-19 and rickettsiae : iii. a study of the antigenic composition of the extracts of bacillus proteus x-19.two substances differing in immunological behavior as well as in certain chemical properties have been isolated from soluble extracts of b. proteus x-19. both substances appear to be polysaccharides. the first substance is precipitated from x-19 crude extracts by a relatively low percentage of alcohol and electrolytes (from one to two and a half volumes of alcohol). when purified as far as possible, it gives a negative biuret reaction, a positive molish and has a nitrogen content of 4 per cent. ...193519870415
a case of meningitis due to b. proteus with recovery. 193620320286
a new species of micro-organism (proteus melanovogenes) causing black rot in eggs. 193720475368
gastro-enteritis associated with proteus vulgaris. 193720780637
the effect of carbohydrates and allied substances on urease production by proteus vulgaris. 193716746341
observations on the bacterial flora of the hen's egg, with a description of new species of proteus and pseudomonas causing rots in eggs. 193820475436
utilization of nicotinic acid and related pyridine compounds by the proteus group of organisms. 194016560303
temperature activation of the urease-urea system using urease of proteus vulgaris. 194116560420
brucella, pasteurella tularensis, and proteus agglutinins in chronic brucellosis. 194116560426
the inhibition of the spreading growth of proteus and other bacteria to permit the isolation of associated streptococci. 194116560477
production of amines by bacteria: the decarboxylation of amino-acids by organisms of the groups clostridium and proteus with an addendum by g. l. brown, f. c. macintosh and p. bruce white. 194116747390
the use of micro-organisms in sugar analysis: the effects of various salts on the activity of proteus vulgaris in removing glucose and some possible sources of error in its use as a reagent for the estimation of glucose. 194116747440
further studies on proteus hydrophilus, the etiological agent in "red leg" disease of frogs. 194216560608
the gas ratio and some correlated distinguishing properties of bacteria of the genus proteus. 194216560609
an anaerogenic strain of proteus. 194220475628
demonstration of agglutinins for bartonella bacilliformis.1. methods of preparing a satisfactory antigen having been developed, a technique for performing an agglutination test with b. bacilliformis is made available. 2. as a result of repeated intravenous injection of living cultures of b. bacilliformis at short intervals, rabbits have been found to produce a high titre of specific agglutinins which, under the conditions obtaining in the present series of experiments, begins to decline after about one month following the last inoculation. 3. sera from ...194219871168
cyanide-sensitive bacterial respiratory systems different from the usual cytochrome-cytochrome oxidase system.aerobic respiration of streptococcus pyogenes and pneumococcus type 1 are strongly inhibited by kcn, nan(3), and na(2)s. the anaerobic glycolysis of glucose by pneumococcus is also inhibited by kcn and nan(3). streptococcus pyogenes, e. coli, pneumococcus type 1, b. subtilis, b. proteus, and staphylococcus aureus did not catalyze the oxygen uptake by p-phenylenediamine in the presence of added cytochrome c or in its absence. yeast cells, b. subtilis, and b. pyocyaneus oxidized p-phenylenediamine ...194219873323
[not available]. 194321011734
[not available]. 194321011735
two artificial "o" forms of proteus vulgaris and their enzymatic properties. 194316560632
a note on the taxonomy of proteus hydrophilus. 194316560691
the characteristics of proteus ammoniae. 194316560712
cytological observations on bact. coli, proteus vulgaris and various aerobic spore-forming bacteria with special reference to the nuclear structures. 194420475706
i. the relation between attachment to the substratum and ingestion by ameba in strychnine sulfate solution and conditioned media : ii. biological assay of conditioned media.1. strychnine sulfate 0.000069 m decreased percentage attachment to the substratum by amoeba proteus in 0.0029 m nacl from 77.3 to 1.3, in 0.0029 m kcl from 40.8 to 2.5, in 0.002 m cacl(2) from 73.3 to 68.0, in 0.002 m mgcl(2) from 85.5 to 83.3. 2. frequency of ingestion of chilomonads by amoeba proteus is increased by adding strychnine sulfate to solutions of nacl, kcl, or cacl(2). frequency of ingestion is increased in nacl solution from 1.3 to 2.3, in kcl from 0.75 to 2.25, and in cacl(2) fro ...194419873390
experimental typhus infection in the eastern cotton rat (sigmodon hispidus hispidus).1. the course of typhus infection in cotton rats has been described, and a relationship between the dose administered and the time of death has been demonstrated. 2. rather incomplete pathological studies indicated that typhus in the cotton rat is an acute infection primarily involving mesothelial tissue, and tissues of mesothelial origin. depending somewhat upon the route of infection, rickettsiae were most easily demonstrated in smears from liver, brain, and pericardial and peritoneal exudates ...194419871421
the chemical alteration of a bacterial surface, with special reference to the agglutination of b. proteus ox-19.the chemical substitution of a bacterial surface has been effected by the addition of benzene sulfonyl chloride to b. proteus ox-19. the substitution of imidazole and amino groups on the bacteria has been followed by the microelectrophoretic method. concomitant changes in the agglutinability of substituted organisms have been observed, without appreciable change in the antibody-combining capacities of the organisms. the significance of these observations has been discussed.194519871488
the reactions in triple-sugar iron agar produced by paracolon and proteus bacilli. 194521012661
[not available]. 194520999529
[not available]. 194521021725
[not available]. 194521015244
on the eyes and reactions to light of proteus anguinus. 194521004249
the nutrition of proteus morganii: sulphur requirements. 194521005568
effect of penicillin on bacillus proteus. 194521007350
[the strains of proteus x isolated from cultures of rickettsia in the intestines of pediculi vestimenti and from the brain of the guinea pig contaminated by otto's passage virus]. 194521066751
the biochemical and serological relationships of the organisms of the genus proteus. 194516560935
further studies on urease production by proteus and related organisms. 194516560936
the nutrition of proteus morganii: sulphur requirements. 194516561005
the reactions in triple-sugar iron agar produced by paracolon and proteus bacilli. 194516561036
a modification of the urease test for proteus. 194517799005
implication of proteus mirabilis in an outbreak of gastroenteritis. 194618016352
further notes on the characteristics of proteus ammoniae. 194616561118
the effect of streptomycin on proteus infections of the chick embryo. 194616561154
urea decomposition as a means of differentiating proteus and paracolon cultures from each other and from salmonella and shigella types. 194616561200
d-amino acid oxidase of proteus morganii. 194621066781
isolation and characterization of two antigenic fractions of proteus ox-19. 194621066631
weil-felix and typhus complement-fixation tests in relapsing fever, with special reference to b. proteus ox-k agglutination. 194621018821
[not available]. 194621019234
the treatment of bacillus proteus infections with nu-445. 194621020389
implication of proteus mirabilis in an outbreak of gastroenteritis. 194621027291
studies of the serology of typhus fever; complement-fixing antigens of rickettsia prowazeki and their relationship to proteus 0x19. 194621003054
the use of polysaccharide of bacillus proteus oxk in the diagnosis of scrub typhus. 194621013741
[not available]. 194621014087
reproductive processes in proteus cultures. 194620987025
the genus proteus. 194620987077
proteus vulgaris septicaemia treated with penicillin. 194620988615
agglutination titres with bacillus proteus (oxk) in human sera. 194620991509
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