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decolorization and biodegradation of reactive blue 13 by proteus mirabilis lag.the decolorization and biodegradation of reactive blue 13 (rb13), a sulphonated reactive azo dye, was achieved under static anoxic condition with a bacterial strain identified as proteus mirabilis lag, which was isolated from a municipal dump site soil near lagos, nigeria. this strain decolorized rb13 (100mg/l) within 5h. the formation of aromatic amine prior to mineralization was supported by fourier transform infrared spectrometry (ftir), which revealed the disappearance of certain peaks, part ...201020832936
enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis.disruption of homeostasis between the host immune system and the intestinal microbiota leads to inflammatory bowel disease (ibd). whether ibd is instigated by individual species or disruptions of entire microbial communities remains controversial. we characterized the fecal microbial communities in the recently described t-bet(-/-) ×rag2(-/-) ulcerative colitis (truc) model driven by t-bet deficiency in the innate immune system. 16s rrna-based analysis of truc and rag2(-/-) mice revealed distinc ...201020833380
screening of the constituents, antimicrobial and antioxidant activity of endemic origanum hypericifolium o. schwartz & p.h. davis.the chemical compositions, total phenol content, antioxidant and antimicrobial activities with oxidant status of the essential oil from an endemic turkish species, origanum hypericifolium, were investigated. steam distillation (sd) was used to isolate the essential oils, and the chemical analyses were performed by gas chromatography-mass spectrometry (gc-ms). the antimicrobial activity was tested by agar disc diffusion method against morganella morganii (clinic isolate), micrococcus flavus (clin ...201020835958
antibacterial activity of some medicinal mangroves against antibiotic resistant pathogenic bacteria.the antibacterial activity of the leaves and bark of mangrove plants, avicennia marina, a. officinalis, bruguiera sexangula, exoecaria agallocha, lumnitzera racemosa, and rhizophora apiculata was evaluated against antibiotic resistant pathogenic bacteria, staphylococcus aureus and proteus sp. soxhlet extracts of petroleum ether, ethyl acetate, ethanol and water were prepared and evaluated the antibacterial activity using agar diffusion method. most of the plant extracts showed promising antibact ...201020838519
preliminary phytochemical screening and antimicrobial studies of lantana indica roxb.the aim of the present study was to investigate the antimicrobial and preliminary phytochemical properties of lantana indica roxb. the aqueous and organic solvent (ethyl acetate and methanol) extracts from the leaves of lantana indica (verbenaceae) were tested against staphylococcus aureus, bacillus subtilis, steptococcus pyrogens, escherichia coli, proteus vulgaris, klebsiella pneumoniae, pseudomonas aeruginosa, salmonella typhi, aspergillus niger and candida albicans by agar well diffusion met ...201020838528
microbial keratitis in the elderly: a 32-year review.to describe the demographic characteristics, associated factors and causative agents of infectious keratitis in the elderly in a tertiary referral center in são paulo, brazil.201020944931
[time course of microbial colonization of different voice prostheses].for the vocal rehabilitation of laryngectomized patients, voice prostheses are actually one of the best known methods. caused by the surface colonisation with bacteria and fungi the life time of the prostheses is limited to 3-4 months.201020949410
antimicrobial activity of doripenem and other carbapenems against gram-negative pathogens from korea.a total of 950 gram-negative bacterial isolates from patients with bacteremia and urinary tract infections were collected from tertiary-care hospitals in korea. in vitro antimicrobial susceptibility testing was performed using broth microdilution test according to clinical and laboratory standards institute protocol. in general, carbapenems such as doripenem, imipenem, and meropenem were very active against enterobacteriaceae, moraxella catarrhalis, pseudomonas aeruginosa, and acinetobacter sp. ...201020950191
light insensitive silver(i) cyanoximates as antimicrobial agents for indwelling medical devices.ten silver(i) cyanoximates of agl composition (l = nc-c(no)-r, where r is electron withdrawing groups: -cn, -c(o)nr(2), -c(o)r' (alkyl), -c(o)oet, 2-heteroaryl fragments such as 2-pyridyl, 2-benzimidazolyl, 2-benzoxazolyl, 2-benzthiazolyl) were synthesized and characterized using spectroscopic methods and x-ray analysis. crystal structures of four complexes were determined and revealed the formation of two-dimensional (2d) coordination polymers of different complexity in which anions exhibit bri ...201020873734
isolation and characterization of bacteria from the gut of bombyx mori that degrade cellulose, xylan, pectin and starch and their impact on digestion.bombyx mori l. (lepidoptera: bombycidae) have been domesticated and widely used for silk production. it feeds on mulberry leaves. mulberry leaves are mainly composed of pectin, xylan, cellulose and starch. some of the digestive enzymes that degrade these carbohydrates might be produced by gut bacteria. eleven isolates were obtained from the digestive tract of b. mori, including the gram positive bacillus circulans and gram negative proteus vulgaris, klebsiella pneumoniae, escherichia coli, citro ...201020874394
resistance phenotype-genotype correlation and molecular epidemiology of citrobacter, enterobacter, proteus, providencia, salmonella and serratia that carry extended-spectrum β-lactamases with or without plasmid-mediated ampc β-lactamase genes in thailand.extended-spectrum β-lactamases (esbls) and plasmid-mediated ampc β-lactamases (pampcs) have been increasingly reported among less commonly encountered genera of enterobacteriaceae. however, little is known regarding the genetic characteristics of resistance genes and epidemiology of these genera. lack of accurate esbl and pampc detection may adversely affect therapeutic outcomes. this study investigated resistance phenotype-genotype correlation and molecular epidemiology among six genera of ente ...201020880563
detection and pfge analysis of esbl-producing isolates of proteus species isolated from patients at tehran hospitals.the production of extended-spectrum β-lactamases (esbls), in particular tem and ctx-m type, by the strains of proteus spp. is a contributing factor to the emergence of bacterial drug resistance. the aim of this study was to screen and determine of esbls genes among strains of proteus spp. at tehran hospitals.201020885345
antimicrobial activities of single aroma compounds.commercially available aroma samples were evaluated for their olfactory quality by professional perfumers and tested for their antimicrobial activity. agar diffusion and agar-dilution were used as test methods and a set of two gram-positive (staphylococcus aureus and enterococcus faecalis) and four gram-negative bacterial strains (escherichia coli, pseudomonas aeruginosa, proteus vulgaris g, klebsiella pneumoniae and salmonella abony) and a yeast, candida albicans, were the test microorganisms. ...201020922992
proteobactin and a yersiniabactin-related siderophore mediate iron acquisition in proteus mirabilis.proteus mirabilis causes complicated urinary tract infections (utis). while the urinary tract is an iron-limiting environment, iron acquisition remains poorly characterized for this uropathogen. microarray analysis of p. mirabilis hi4320 cultured under iron limitation identified 45 significantly upregulated genes (p ≤ 0.05) that represent 21 putative iron-regulated systems. two gene clusters, pmi0229-0239 and pmi2596-2605, encode putative siderophore systems. pmi0229-0239 encodes a non-ribosomal ...201020923418
novel chalcones and 1,3,5-triphenyl-2-pyrazoline derivatives as antibacterial agents.novel sixteen chalcones and thirteen 1,3,5-triphenyl-2-pyrazolines were synthesized and characterized using ft-ir, hr-mass, nmr (¹h-nmr, ¹³c-nmr, 135 dept, ¹h-¹h cosy and ¹h and ¹³c cosy) and xrd. these compounds were evaluated for their antibacterial activity against six micro-organisms, namely bacillus subtilis ncim 2718, staphylococcus aureus ncim 5021, salmonella typhi ncim 2501, enterobacter aerogenes ncim 5139, pseudomonas aeruginosa ncim 5029, and proteus vulgaris ncim 2813 by twofold dil ...201020925692
extended-spectrum β-lactamases in gram negative bacteria.extended-spectrum β-lactamases (esbls) are a group of plasmid-mediated, diverse, complex and rapidly evolving enzymes that are posing a major therapeutic challenge today in the treatment of hospitalized and community-based patients. infections due to esbl producers range from uncomplicated urinary tract infections to life-threatening sepsis. derived from the older tem is derived from temoniera, a patient from whom the strain was first isolated in greece. β-lactamases, these enzymes share the abi ...201020927289
tigecycline activity: low resistance rates but problematic disc breakpoints revealed by a multicentre sentinel survey in the uk.a multicentre surveillance of tigecycline activity against relevant pathogens in the uk.201020930043
chitosan-based polyherbal toothpaste: as novel oral hygiene product.the objective of the present work was to develop chitosan-based polyherbal toothpaste and evaluate its plaque-reducing potential and efficacy in reduction of dental pathogens.201020930349
essential oil constituents of illicium griffithii and its antimicrobial activity.the essential oil of the fruit of illicium griffithii hook f. et thoms. was extracted using clevenger's apparatus. forty-one compounds were characterized by gas chromatography-mass spectroscopy (gc-ms). 4-methyl-6-(2-propenyl)-1,3-benzodioxole was characterized as the major constituent, followed by linalool amongst the volatile constituents. the essential oil was found to be effective against aspergillus niger, penicillium spp. and saccharomyces cerevisiae and possessed considerable activity aga ...201020931081
a mutational analysis and molecular dynamics simulation of quinolone resistance proteins qnra1 and qnrc from proteus mirabilis.the first report on the transferable, plasmid-mediated quinolone-resistance determinant qnra1 was in 1998. since then, qnr alleles have been discovered worldwide in clinical strains of gram-negative bacilli. qnr proteins confer quinolone resistance, and belong to the pentapeptide repeat protein (prp) family. several prp crystal structures have been solved, but little is known about the functional significance of their structural arrangement.201020932305
understanding interactive characteristics of bioelectricity generation and reductive decolorization using proteus hauseri.this first-attempt study quantitatively explored interactive characteristics of bioelectricity generation and dye decolorization in air-cathode single-chamber microbial fuel cells (mfcs) using indigenous proteus hauseri zmd44. after approx. 15 cycles (30 days) acclimatization in dye-bearing cultures, p. hauseri could express its stable capability of simultaneous bioelectricity generation and color removal (sbp&cr) in mfcs. evidently, appropriate acclimation strategy for formation of the electroc ...201020932743
swab and aspiration specimen collection methods and antibiogram in chronic suppurative otitis media at jos university teaching hospital: which is superior?chronic suppurative otitis media is a very common otologic problem in our environment. appropriate methods for obtaining sample specimens for specific bacteria isolation has generated a lot of controversy. the simplest method available in our environment is the traditional swab method which, however, has been condemned on the basis of introducing contaminants. the objectives of this study were to compare the bacterial yield and the antibiogram of two specimen collection methods: the traditional ...201020935423
domoic acid--a new toxin in the croatian adriatic shellfish toxin profile.this is the first study that presents concentrations of domoic acid detected in the whole shellfish tissue from breeding and harvesting areas along the croatian coast of the adriatic sea during the period 2006 to 2008. shellfish sample analyses after sax cleaning procedures, using a uv-dad-hplc system, showed the presence of domoic acid in four species. the most prevalent of those species were the blue mussel (mytilus galloprovincialis), followed by european flat oyster (ostrea edulis), mediterr ...201020938398
a history of von recklinghausen's nf1.while the study of genetic diseases is a rather recent development in science, von recklinghausen's neurofibromatosis (nf1) has a rich pictorial history, seemingly dating back to the thirteenth century. in 1768, akenside published a scientifically-based description of nf1, recognizing that the monsters of scholars, such as parè and aldrovandi, in fact suffered from a disorder of the nerves. the neuromas of nf1 were first detailed by smith in 1849, but frederick von recklinghausen is credited wit ...201020938857
synergy of nitric oxide and silver sulfadiazine against gram-negative, gram-positive, and antibiotic-resistant pathogens.the synergistic activity between nitric oxide (no) released from diazeniumdiolate-modified proline (proli/no) and silver(i) sulfadiazine (agsd) was evaluated against escherichia coli, enterococcus faecalis, proteus mirabilis, pseudomonas aeruginosa, staphylococcus aureus and staphylococcus epidermidis using a modified broth microdilution technique and a checkerboard-type assay. the combination of no and agsd was defined as synergistic when the fractional bactericidal concentration (fbc) was calc ...201020939612
[the bacteriological profile of bacteriuria in residents of a long-term geriatric facility].little is known on the bacteriological profile of consecutive urine samples in elderly patients institutionalized in nursing homes.201020941920
[dynamics of acquires resistance in the main gramnegative pathogens of surgical infections to beta-lactams in 2004-2008].resistance of 2134 clinical isolates of etiologically significant species of gramnegative bacteria to 5 beta-lactam antibiotics, i. e. cefepime, piperacillin/tazobactam, cefoperazone/sulbactam, imipenem and ceftazidime (the 3rd generation cephalosporin) as the reference drug was investigated for the period of 5 years (2004-2008). in total, 554 strains of e. coli, 578 strains of p. aeruginosa, 255 strains of acinetobacter spp., 161 strains of proteus mirabilis, 359 strains of klebsiella pneumonia ...201020583554
synthesis and biological activities of novel amine-derived bis-azoles as potential antibacterial and antifungal agents.a series of novel amine-derived bis-azole compounds were designed by the systematical structural modification of fluconazole and synthesized by a convenient and efficient method, and the antimicrobial activities for all prepared compounds were evaluated in vitro against six representative bacterial strains and two fungal strains. bioactive results indicated that some synthesized compounds exhibited moderate or even better activities in comparison with the reference drugs. especially, bis-imidazo ...201020598399
in vitro bactericidal activity of human beta-defensin 2 against nosocomial strains.human beta-defensin 2 (hbd-2) is a 41-amino acid cationic peptide of the innate immune system that serves as antimicrobial molecule. we determined the bactericidal activity of synthetic hbd-2 against nosocomial strains belonging to eight different bacterial species and exhibiting various antimicrobial resistance phenotypes. the native disulfide connectivity was found essential for the bactericidal activity of hbd-2, while sodium chloride concentration was reversely associated with its potency. h ...201020600430
selective strategy for urethral catheterization in febrile young girls to confirm urinary tract infection diagnosis.urinary tract infections (utis) are a common source of bacterial infections in childhood. making a proper diagnosis is important but requires invasive urine collection techniques. we aimed to derive a clinical decision rule to identify non-toilet-trained febrile girls at high risk for utis to restrict urethral catheterizations (ucs) to this high-risk group of patients.201020606484
[nosocomial infections at clinical centre in kragujevac--prevalence study].nosocomial infections (nis) are a serious health problem in hospitals worldwide and are followed by a series of consequences, medical, judicial, ethical and economic.201020607980
clove syndrome with nevus unis lateris: report of a case.congenital lipomatous overgrowth, vascular malformations, and epidermal nevi (clove) syndrome is a recently described syndrome similar to proteus syndrome but lacking the progressive or distorting bony overgrowth of proteus syndrome. we describe a neonate with features of clove syndrome and nevus unius lateris.201020609160
rapidly spreading ctx-m-type beta-lactamase-producing proteus mirabilis in japan.in recent years, increased isolation of extended-spectrum beta-lactamase (esbl)-producing proteus mirabilis has been reported in japan. we undertook an investigation to determine the prevalence of esbl-producing p. mirabilis isolated in japan and to characterise the genotype. seventy-four p. mirabilis isolates recovered from specimens at 54 hospitals in japan between march and october 2006 were included in the study. of the 74 p. mirabilis isolates examined, 28 (37.8%) were esbl-producers. the b ...201020609568
laboratory surveillance for prospective plasmid-mediated ampc beta-lactamases in the kinki region of japan.extended-spectrum beta-lactamases, plasmid-mediated ampc beta-lactamases (pabls), and plasmid-mediated metallo-beta-lactamases confer resistance to many beta-lactams. in japan, although several reports exist on the prevalence of extended-spectrum beta-lactamases and metallo-beta-lactamases, the prevalence and characteristics of pabls remain unknown. to investigate the production of pabls, a total of 22,869 strains of 4 enterobacterial species, escherichia coli, klebsiella pneumoniae, klebsiella ...201020610688
chemical composition and biological activities of santiria trimera (burseraceae) essential oils from gabon.water-distilled essential oils from leaves and bark of santiria trimera (oliv.) aubrév. (burseraceae) collected in gabon were analyzed using capillary gc-fid and gc-ms. the leaf essential oil, which is described for the first time, was dominated by sesquiterpenes (76.5%), among which alpha-humulene (34.6%) and beta-caryophyllene (14.9%) were the major components. the bark essential oil was almost exclusively monoterpenic, with alpha-pinene (51.5%) and alpha-terpineol (16.8%) as main constituents ...201020614835
isoprenoid metabolism as a therapeutic target in gram-negative pathogens.gram-negative enterobacteria include a variety of human pathogens, perhaps most notably e. coli, salmonella, shigella, yersinia, and proteus. while there are treatment options for the diseases caused by these organisms, multi-drug resistance is often a problem and development of novel antibiotics has lagged over recent years. in humans, the isoprenoid biosynthetic pathway has become a subject of intense research for therapeutic modulation of human enzymes in diseases including hypercholesterolem ...201020615187
functional identification of the proteus mirabilis core lipopolysaccharide biosynthesis genes.in this study, we report the identification of genes required for the biosynthesis of the core lipopolysaccharides (lpss) of two strains of proteus mirabilis. since p. mirabilis and klebsiella pneumoniae share a core lps carbohydrate backbone extending up to the second outer-core residue, the functions of the common p. mirabilis genes was elucidated by genetic complementation studies using well-defined mutants of k. pneumoniae. the functions of strain-specific outer-core genes were identified by ...201020622068
rapid paper disk test for identification of helicobacter pylori in mixed cultures of gerbil gastric homogenates.a method denominated rapid paper disk test (rpdt) was developed to identify h. pylori colonies in complex cultures obtained from gerbil gastric homogenates. identification is based on a characteristic reaction pattern (rp) for h. pylori colonies given by the combination of the urease-oxidase activities on a paper disk. compared to the rps obtained from gerbil's intestinal tract isolated bacteria, h. pylori rp is completely distinguishable, even from those of bacteria that share one or both activ ...201020624429
history of polish neurology and neurosurgery. brudziński, jósef . 201020625969
overexpression and characterization in bacillus subtilis of a positionally nonspecific lipase from proteus vulgaris.a proteus vulgaris strain named t6 which produced lipase (pvl) with nonpositional specificity had been isolated in our laboratory. to produce the lipase in large quantities, we cloned its gene, which had an opening reading frame of 864 base pairs and encoded a deduced 287-amino-acid protein. the pvl gene was inserted into the escherichia coli expression vector pet-dsba, and active lipase was expressed in e. coli bl21 cells. the secretive expression of pvl gene in bacillus subtilis was examined. ...201020490605
volatiles emitted from eight wound-isolated bacteria differentially attract gravid screwworms (diptera: calliphoridae) to oviposit.bovine blood inoculated with bacteria isolated from screwworm [cochliomyia hominivorax (coquerel) (diptera: calliphoridae)]-infested animal wounds was tested as an attractant for oviposition for gravid screwworms. eight species of gram-negative coliform (enterobacteriaceae) bacteria mixed with bovine blood singly or all species combined and incubated for various times produced volatiles that attracted gravid flies in a cage bioassay in varying numbers. in 15-min duration tests, volatiles from fi ...201020496582
regulation of gene expression during swarmer cell differentiation in proteus mirabilis.the gram-negative bacterium proteus mirabilis can exist in either of two cell types, a vegetative cell characterized as a short rod and a highly elongated and hyperflagellated swarmer cell. this differentiation is triggered by growth on solid surfaces and multiple inputs are sensed by the cell to initiate the differentiation process. these include the inhibition of flagellar rotation, the accumulation of extracellular putrescine and o-antigen interactions with a surface. a key event in the diffe ...201020497230
pulmonary manifestations and management of proteus syndrome.proteus syndrome is a very rare, sporadic and congenital condition that is characterized by postnatal mosaic overgrowth. this disorder is thought to be caused by a somatic gene mutation, but the exact etiology is unknown. commonly involved tissues include connective tissue, bone, skin and the central nervous system. another less common symptom involves pulmonary emphysematous changes. this report documents a 25-year-old man with proteus syndrome who presented with progressive exertional dyspnea ...201020497874
may chlamydia trachomatis be an aetiological agent of chronic prostatic infection?chlamydia trachomatis infection is the most common sexually transmitted bacterial disease. the objective of this study was to establish the presence/absence of c. trachomatis in 98 patients with chronic complaints about the prostate and to evaluate the role of this bacterium in the inflammation of the gland. we performed culture and microscopical examination of pre-massage/post-massage urine and expressed prostatic secretions (eps). in all cases, culture on mccoy cells and polymerase chain react ...201020500746
[a case of large vesicourethral stone resulting from long-term retention of a foley catheter].we report a case of a large vesicourethral stone resulting from a long-term indwelling urethral catheter. a 66-year-old man visited our hospital emergency room on october 24, 2006 with a chief complaint of difficult urination. although a urethral catheter was inserted temporarily based on the diagnosis of the doctor on duty, the patient did not return to our hospital for follow-up examination. on july 10, 2008, he was wheeled into our hospital with symptoms of general fatigue, urinary retention ...201020519926
antimicrobial susceptibility of gram-negative nonurinary bacteria to fosfomycin and other antimicrobials.fosfomycin is an antimicrobial commonly used in uncomplicated urinary tract infections. the microbiological effectiveness of fosfomycin against nonurinary gram-negative isolates has not been widely investigated. the aim of this study was to evaluate the in vitro activity of fosfomycin against gram-negative nonurinary isolates in a region of greece where considerable antimicrobial resistance has been detected.201020521939
synthesis, nematicidal and antimicrobial activity of 3-(5-3-methyl-5-[(3-methyl-7-5-[2-(aryl)-4-oxo-1,3-thiazolan-3-yl]-1,3,4-thiadiazol-2-ylbenzo[b]furan-5-yl)methyl]benzo[b]furan-7-yl-1,3,4-thiadiazol-2-yl)-2-(aryl)-1,3-thiazolan-4-one.a new series of 3-(5-3-methyl-5-[(3-methyl-7-5-[2-(aryl)-4-oxo-1,3-thiazolan-3-yl]-1,3,4-thiadiazol-2-ylbenzo[b]furan-5-yl)methyl]benzo[b]furan-7-yl-1,3,4-thiadiazol-2-yl)-2-(aryl)-1,3-thiazolan-4-one 5a-j has been synthesized by the reaction of n2-[(e)-1-(4-methylphenyl)methylidene]-5-(3-methyl-5-[3-methyl-7-(5-[(e)-1-(4-methylphenyl)methylidene]amino-1,3,4-thiadiazol-2-yl)benzo[b]furan-5-yl]methylbenzo[b]furan-7-yl)-1,3,4-thiadiazol-2-amine 4a-j with thioglycolic acid. chemical structures of a ...201020522990
the use of lytic bacteriophages in the prevention and eradication of biofilms of proteus mirabilis and escherichia coli.antibiotics have been the cornerstone of the clinical management of bacterial infections since their discovery in the early part of the last century. eight decades later, their widespread, often indiscriminate use, has resulted in an overall reduction in their effectiveness, with reports of multidrug-resistant bacteria now commonplace. increasing reliance on indwelling medical devices, which are inherently susceptible to biofilm-mediated infections, has contributed to unacceptably high rates of ...201020528927
the group of epidermal nevus syndromes part i. well defined phenotypes.the epidermal nevus syndromes represent a group of distinct disorders that can be distinguished by the type of associated epidermal nevus and by the criterion of presence or absence of heritability. well defined syndromes characterized by organoid epidermal nevi include schimmelpenning syndrome, phacomatosis pigmentokeratotica, nevus comedonicus syndrome, angora hair nevus syndrome, and becker nevus syndrome. the molecular basis of these disorders has so far not been identified. by contrast, the ...201020542174
the group of epidermal nevus syndromes part ii. less well defined phenotypes.in addition to the well established epidermal nevus syndromes, such as schimmelpenning, becker, proteus, child, or nevus comedonicus syndromes, the group of less well defined phenotypes associated with epidermal nevi presently includes nevus trichilemmocysticus syndrome, didymosis aplasticosebacea, scalp syndrome (sebaceous nevus, central nervous system malformations, aplasia cutis congenita, limbal dermoid,and pigmented nevus), gobello syndrome, bäfverstedt syndrome, nevada syndrome (nevus epid ...201020542175
comparative in vitro activity of cefditoren and other antimicrobials against enterobacteriaceae causing community-acquired uncomplicated urinary tract infections in women: a spanish nationwide multicenter study.cefditoren is a third-generation orally administered cephalosporin with a broad spectrum of activity against gram-positive and gram-negative bacterial species. after an oral 400-mg single dose, the mean concentrations in urine are 186.5 mg/l at 2 to 4 h and 12.7 mg/l at 8 to 12 h, and it is a potential drug to be used in the treatment of urinary tract infection (uti). we performed a multicenter nationwide study in spain in order to determine the in vitro activity of cefditoren and other comparat ...201020542206
[detection of bla(ctx-m) beta-lactamase genes in extended-spectrum beta-lactamase producing gram-negative bacteria].widespread production of ctx-m type extended-spectrum beta-lactamases (esbl) in enterobacteriaceae strains which are resistant to extended-spectrum cephalosporins is the most remarkable example for rapid and global spread of plasmid mediated antimicrobial resistance in bacteria. consecutive 200 esbl producing enterobacteriaceae strains out of 1640 isolates that were obtained from clinical samples (167 urine, 11 wound, 7 bronchoalveolar lavage, 3 peritoneal fluid, 2 cerebrospinal fluid, 2 biopsy, ...201020549952
emergence of proteus mirabilis isolates producing tem-52 extended-spectrum beta-lactamases in croatia.an increased frequency of extended-spectrum beta-lactamase (esbl)-positive proteus mirabilis isolates was observed recently in the clinical hospital center split in croatia. the aim of this study was the molecular characterization of esbls in p. mirabilis isolates from this hospital.201020551637
a genome-wide analysis of loss of heterozygosity and chromosomal copy number variation in proteus syndrome using high-density snp microarrays.excessive cell proliferation and genetic changes such as loss of an allele (loss of heterozygosity (loh)) or amplifications or deletions of parts of chromosomes (copy number variations (cnv)) are common findings in cancers. it is unknown whether these changes are also present in patients with overgrowth syndromes, although the presence of small-scale cnvs (such as duplication of 11p15 in beckwith-wiedemann syndrome), excessive cell proliferation and an increased frequency of tumors have all been ...201020555334
determinants of beta-lactam resistance in meningitis-causing enterobacteriaceae in brazil.this study analyzed resistance determinants in extended-spectrum beta-lactamase (esbl)-producing enterobacteria and the epidemiology of 11 escherichia coli isolates obtained from meningitis patients in a region of brazil from 2000 to 2005. esbl-encoding genes and their genetic environment were investigated by pcr and sequencing. the gene blactx-m-2 was identified in 3 different enterobacteria (e. coli, serratia marcescens, and proteus mirabilis) downstream of the insertion sequence iscr1 (locali ...201020555402
synthesis, antibacterial activity evaluation and qsar studies of novel dispiropyrrolidines.a series of novel dispiropyrrolidines have been synthesized through 1,3-dipolar cycloaddition of an azomethine ylide generated from sarcosine and isatin with the dipolarophile 3-benzylidene-1-methyl-pyrrolidine-2,5-dione. their antibacterial activity was evaluated against bacillus subtilis ncim 2718, staphylococcus aureus ncim5021, salmonella typhi ncim2501, pseudomonas aeruginosa ncim 5029 and proteus vulgaris ncim2813 by two fold dilution method. compound 6e exhibits reasonably good activity a ...201020556891
generation of chitin-derived oligosaccharides toxic to pathogenic bacteria using chia74, an endochitinase native to bacillus thuringiensis.to demonstrate that an endochitinase (chia74) native to bacillus thuringiensis can be used to generate chitin-derived oligosaccharides (ogs) with antibacterial activity against a number of aetiological agents of disease, including bacteria that cause diarrhoeal and emetic syndromes in humans.201020557451
high prevalence and molecular characterization of extended-spectrum β-lactamase-producing proteus mirabilis strains in southern croatia.the aim of this study was to determine the prevalence and antibiotic resistance rates of extended-spectrum β-lactamase (esbl)-producing proteus mirabilis strains isolated from inpatients at the split university hospital (southern croatia) during a survey performed between 2005 and 2008. a total of 2152 consecutive isolates of p. mirabilis were isolated. the prevalence was 0.5 % in 2005 and increased significantly to 20.9 % by 2008. strains were most frequently isolated from urine (36.5 %) and br ...201020558587
performance of the oxoid m.i.c.evaluator strips compared with the etest assay and bsac agar dilution.the oxoid m.i.c.evaluator (m.i.c.e; thermo fisher scientific) comprises an antibiotic gradient on a plastic support. we compared its performance with etest--a similar product--using bsac agar dilution as a reference.201020562429
prevalence of asymptomatic bacteriuria in type 2 diabetic subjects with and without microalbuminuria.abstract:201020565718
antimicrobial susceptibility and beta-lactamase production of selected gram-negative bacilli from two croatian hospitals: mystic study results.the meropenem yearly susceptibility test information collection (mystic) programme is a global, longitudinal resistance surveillance network that monitors the activity of meropenem and compares its activity with other broadspectrum antimicrobial agents. we now report the antimicrobial efficacy of meropenem compared to other broad-spectrum agents within the selective gram-negative pathogen groups from two croatian hospitals investigated between 2002-2007. a total of 1510 gram-negative pathogens w ...201020566417
chromosomally encoded blacmy-2 located on a novel sxt/r391-related integrating conjugative element in a proteus mirabilis clinical isolate.integrating conjugative elements (ices) are mobile genetic elements that can transfer from the chromosome of a host to the chromosome of a new host through the process of excision, conjugation, and integration. although sxt/r391-related ices, originally demonstrated in vibrio cholerae o139 isolates, have become prevalent among v. cholerae isolates in asia, the prevalence of the ices among gram-negative bacteria other than vibrio spp. remains unknown. in addition, sxt/r391-related ices carrying g ...201020566768
synthesis and antimicrobial activities of some quaternary morpholinium chlorides.the synthesis and antimicrobial activity of 31 morpholinium chlorides, divided into five series depending on the substituents attached to the nitrogen atom, n-carboxyalkyl-morpholinium chlorides (1a-e), n-carbalkoxymethyl-n-methyl-morpholinium chlorides (2a-f), n-carbethoxymethyl-n-alkyl-morpholinium chlorides (3a-g), n-carbalkoxymethyl-n-dodecyl-morpholinium chlorides (4a-f) and n-carboxymethyl-n-alkyl-morpholinium chlorides (5a-g) is reported. the compounds investigated were tested for antimic ...201020568530
chemical composition of the sfe-co extracts from cajanus cajan (l.) huth and their antimicrobial activity in vitro and in vivo.the in vitro and in vivo antimicrobial activities of sfe-co₂(supercritical fluid extraction) extracts and ethanol extracts from cajanus cajan (l.) huth were investigated. the flavonoid compounds orientin, vitexin, isovitexin, pinostrobin and the stilbene cajaninstilbene acid were detected in sfe-co₂ extracts by hplc-dad. in vitro antimicrobial activities of the extracts were evaluated against eight microbial strains (the bacteria staphylococcus epidermidis, staphylococcus aureus, bacillus subtil ...201020576412
synthesis, antibacterial activity evaluation and qsar studies of novel dispiropyrrolidines.a series of novel dispiropyrrolidines have been synthesized through 1,3-dipolar cycloaddition of an azomethine ylide generated from sarcosine and isatin with the dipolarophile 3-benzylidene-1-methyl-pyrrolidine-2,5-dione. their antibacterial activity was evaluated against bacillus subtilis ncim 2718, staphylococcus aureus ncim5021, salmonella typhi ncim2501, pseudomonas aeruginosa ncim 5029 and proteus vulgaris ncim2813 by two fold dilution method. compound 6e exhibits reasonably good activity a ...201020580853
molecular and genetic analyses of the putative proteus o antigen gene locus.proteus species are well-characterized opportunistic pathogens primarily associated with urinary tract infections (uti) of humans. the proteus o antigen is one of the most variable constituents of the cell surface, and o antigen heterogeneity is used for serological classification of proteus isolates. even though most proteus o antigen structures have been identified, the o antigen locus has not been well characterized. in this study, we identified the putative proteus o antigen locus and demons ...201020581173
clinical features of proteus mirabilis pneumonia.in this study, we clinically reviewed 13 patients with proteus mirabilis pneumonia who were admitted for treatment to kawasaki medical school kawasaki hospital, okayama, japan, between april 2006 and july 2009. clinical features were retrospectively reviewed. results showed that: (1) hospital-acquired pneumonia occurred in elderly patients with underlying diseases such as cerebrovascular disease; (2) some patients had complications of urinary tract infection due to p. mirabilis; (3) preadministr ...201020502932
predictors, treatment, and outcomes of non-pseudomonas gram-negative peritonitis.non-pseudomonas gram-negative (npgn) peritonitis is a frequent, serious complication of peritoneal dialysis; however, previous reports have been limited to small, single-center studies. to gain insight on the frequency, predictors, treatment, and outcomes of npgn peritonitis, we analyzed data in the anzdata registry of all adult australian peritoneal dialysis patients over a 39-month period using multivariate logistic and multilevel poisson regressions. there were 837 episodes of npgn peritoniti ...201020505659
double synergy differential test for detection of plasmid-mediated ampc-type beta-lactamases in proteus mirabilis. 201020508001
communal action of microbial cultures for red he3b degradation.the consortium pmb11 consisting of three bacterial species, originally isolated from dye contaminated soil was identified as bacillus odysseyi suk3, morganella morganii suk5 and proteus sp. suk7. the consortium possessed the ability to decolorize various textile dyes as well as mixtures of dyes. pmb11 could decolorize red he3b (50 mg l(-1)) with 99% of decolorization within 12 h in nutrient broth, while in mineral medium it could decolorize up to 97% within 24h. induction in the activities of va ...201020510505
most frequent causes of urinary tract infections in children.to determine the most frequent causes of urinary tract infection (uti) amongst children according to gender and age.201020514772
development of an oregano-based ointment with anti-microbial activity including activity against methicillin-resistant staphlococcus aureus.increasing antibiotic resistance has prompted a search for new compounds with anti-microbial activity. in the authors' previous study, oregano extract was identified as one of the most potent anti-microbial compounds. the disk diffusion method was employed to assess the degree of inhibition against various microorganisms, and the bacteriostatic or bactericidal mechanism of action. disk diffusion studies showed that oregano was found to be bacteriostatic for staphylococcus aureus (s. aureus) and ...201020514796
acute pyelonephritis can have serious complications.urinary tract infection (uti) may predominantly involve the lower urinary tract, i.e. acute cystitis, or upper urinary tract consisting of the renal pelvis and kidney,, i.e. acute pyelonephritis the incidence of acute pyelonephritis is higher in young women than in men but the incidence in men over 65 is similar to that in older women. women have up to a 10% risk of recurrent acute pyelonephritis in the year following a first acute episode. the equivalent risk in men is 6%. acute pyelonephritis ...201020486480
antibacterial and antifungal activities of (beta)-carboline alkaloids of peganum harmala (l) seeds and their combination effects.the β-carboline alkaloids of peganum harmala l were extracted through a bioassay-guided fractionation and their antimicrobial activities were investigated. results revealed significant differences (p>0.05) between compounds depending on the microorganism tested and the application method. when examined individually, harmine was the most effective against proteus vulgaris, bacillus subtilis and candida albicans where inhibition zones ranged between 21.2 and 24.7 mm. potentiality of the alkaloids ...201020398742
differences in biofilm formation and aggregative adherence between beta-lactam susceptible and beta-lactamases producing p. mirabilis clinical isolates.biofilm formation of multidrug resistant (mdr) extended-spectrum beta-lactamase (esbetal) producing proteus mirabilis isolates from a long-term care and rehabilitation facility (ltcrf) in northern italy was evaluated. a total of 10 strains, 4/10 producing the acquired ampc beta-lactamase cmy-16, 3/10 producing the esbetal tem-92 and the remaining negative for the presence of beta-lactamase genes, were studied using standard adherence assays on titer plates. tests were performed in three differen ...201020402412
decolorization and biodegradation of reactive dyes and dye wastewater by a developed bacterial consortium.a bacterial consortium (consortium gr) consisting of proteus vulgaris ncim-2027 and micrococcus glutamicus ncim-2168 could rapidly decolorize and degrade commonly-used sulfonated reactive dye green he4bd and many other reactive dyes. consortium gr shows markedly higher decolorization activity than that of the individual strains. the preferable physicochemical parameters were identified to achieve higher dye degradation and decolorization efficiency. the supplementation of cheap co-substrates (e. ...201020407917
species differentiation of seafood spoilage and pathogenic gram-negative bacteria by maldi-tof mass fingerprinting.species differentiation is important for the early detection and identification of pathogenic and food-spoilage microorganisms that may be present in fish and seafood products. the main 26 species of seafood spoilage and pathogenic gram-negative bacteria, including aeromonas hydrophila, acinetobacter baumanii, pseudomonas spp., and enterobacter spp. among others, were characterized by matrix-assisted laser desorption ionization-time of flight mass spectrometry (maldi-tof ms) of low molecular wei ...201020408567
pathogenicity of aeromonas hydrophila, klebsiella pneumoniae, and proteus mirabilis to brown tree frogs (litoria ewingii).bacterial dermatosepticemia, a systemic infectious bacterial disease of frogs, can be caused by several opportunistic gram-negative bacterial species including aeromonas hydrophila, chryseobacterium indologenes, chryseobacterium meningosepticum, citrobacter freundii, klebsiella pneumoniae, proteus mirabilis, pseudomonas aeruginosa, and serratia liquifaciens. here we determined the pathogenicity of 3 bacterial species (aeromonas hydrophila, klebsiella pneumoniae, and proteus mirabilis) associated ...201020412685
recovery and screening for antibiotic susceptibility of potential bacterial pathogens from the oral cavity of shark species involved in attacks on humans in recife, brazil.the number of incidents involving sharks and humans at beaches in recife, on the north-eastern brazilian coast, is among the highest worldwide. in addition, wound infections in survivors are common; but the nature and risk of the aetiological agents is unknown. in the present study, 81 potential bacterial pathogens were identified in the oral cavity of sharks involved in attacks in recife, and were subjected to antibiotic susceptibility tests using the standardized disc-diffusion method. the maj ...201020413619
the effect of ph and chemical preservatives on the growth of bacterial isolates from some nigerian packaged fruit juices.bacterial pathogens were isolated from some nigerian packaged fruit juices. the isolates were characterized and identified as bacillus licheniformis, aeromonas hydrophila, bacillus circulans, proteus morganii, pseudomonas cepacia, bacillus alvei and pseudomonas chlororaphis. the antibiotic susceptibility profile of the seven isolates was determined and it was discovered that 65% of the microorganisms isolated were resistance to the antibiotic used while 35% were sensitive. the effect of ph, benz ...201020415148
[characteristics of urinary tract infections in different patient subpopulations and depending on the bladder emptying system].to analyze the prevalence and etiology of urinary tract infection in patients with neurogenic bladder depending on the bladder emptying system used as compared to a population with no neurological impairment. to assess perception of urinary tract infection by patients with neurogenic bladder.201020416242
ureases as a target for the treatment of gastric and urinary infections.urease is known to be a major contributor to pathologies induced by helicobacter pylori and proteus species. in h pylori, urease allows the bacteria to survive in an acidic gastric environment during colonisation, playing an important role in the pathogenesis of gastric and peptic ulcers. ureolytic activity also results in the production of ammonia in close proximity to the gastric epithelium, causing cell damage and inflammation. in the case of proteus species (notably proteus mirabilis) infect ...201020418234
bacteriological study of aerobic isolates from plantar ulcers of paucibacillary leprosy patients.plantar ulcers commonly occur in leprosy patients, which usually recur and cause morbidity in such cases.201020418976
assessing the emergence of resistance: the absence of biological cost in vivo may compromise fosfomycin treatments for p. aeruginosa infections.fosfomycin is a cell wall inhibitor used efficiently to treat uncomplicated urinary tract and gastrointestinal infections. a very convenient feature of fosfomycin, among others, is that although the expected frequency of resistant mutants is high, the biological cost associated with mutation impedes an effective growth rate, and bacteria cannot offset the obstacles posed by host defenses or compete with sensitive bacteria. due to the current scarcity of new antibiotics, fosfomycin has been propo ...201020419114
antibiotic resistance in community-acquired urinary tract infections: prevalence and risk factors.this study aimed to identify the agents causing community-acquired urinary tract infections (cautis) and their resistance patterns and to investigate risk factors for esbl production.201020424552
bacterial contamination of boar semen affects the litter size.one hundred and fifteen semen samples were collected from 115 different boars from two farms in cuba. the boars belonged to five different breeds. evaluation of the semen sample characteristics (volume, ph, colour, smell, motility of sperm cells) revealed that they meet international standards. the samples were also tested for the presence of agglutinated sperm cells and for bacterial contamination. seventy five percent of the ejaculates were contaminated with at least one type of bacteria and e ...201020427136
antimicrobial activity and a sar study of some novel benzimidazole derivatives bearing hydrazone moiety.in this study 12 novel benzimidazole compounds bearing hydrazone moiety were synthesized in order to investigate their possible antibacterial and antifungal activity. structures of the synthesized compounds were elucidated by spectral data. six different gram-negative and four different gram-positive bacterial strains were used in antibacterial activity tests. antifungal activity tests were also performed against three different fungal strains. most of the test compounds found to be significantl ...201020451306
proteus takayasu's arteritis with unusual intracranial granulomatosis as initial manifestation.takayasu's arteritis (ta) is an inflammatory vasculitis of aorta and its branches, its low incidence limited our recognition to this entity. we sometimes can confuse this desease with polyarteritis nodosa and other vasculitis when no conventional "big artery" involved in ta cases. here we report a 26-year-old man with takayasu's arteritis who presented with a provisional intracranial granulomatosis first and then saccular aneurysms between celiac trunk and arteria hepatica communis and many othe ...201020354858
distinct bacterial colonization patterns of escherichia coli subtypes associate with rheumatoid factor status in early inflammatory arthritis.the aetiology of ra is unknown; however, bacterial exposure, particularly to escherichia coli, proteus mirabilis and klebsiella pneumoniae, has been linked to disease pathogenesis. the strongest association was observed for rf(+) ra. we compare colonization patterns of these bacteria, and the anti-bacterial antibody levels in early onset rf(+) and rf(-) inflammatory arthritis.201020360042
microbial colonization of tracheoesophageal voice prostheses (provox2) following total laryngectomy.the purpose of this study was to determine the presence of individual microorganisms and the most frequent microbial combinations in the biofilm of the indwelling provox2 voice prosthesis in situ. furthermore, we wanted to evaluate the possible influence of biofilm composition on the mean and median lifetime of these voice prostheses. over a 5-year period, implantation of a provox2 voice prosthesis was performed in 85 patients, or 90% of the overall number of patients who underwent total larynge ...201020432044
antimicrobial susceptibility patterns of community-acquired uropathogens in tehran, iran.antibiotic resistance of urinary tract pathogens has increased worldwide. knowledge of the antibiotic resistance patterns of uropathogens in specific geographical locations is an important factor for choosing an appropriate empirical antimicrobial treatment. the aim of this study was to provide information regarding local resistance patterns of urinary pathogens to the commonly used antibiotics in tehran, iran.201020440056
neurognostics question. metamorphosis of a man: diagnosing joseph merrick. proteus syndrome. 201020446160
prolonged bacteraemia caused by vim-1 metallo-beta-lactamase-producing proteus mirabilis: first report from italy.persistent bacteraemia arising from a case of post-operative mediastinitis as a result of a proteus mirabilis isolate, possessing two class 1 integrons carrying bla(vim-1) and aada2 gene cassettes located on chromosomal and plasmidic dna, respectively, is reported. despite the in vitro susceptibility to carbapenems, meropenem therapy failed, whereas the patient responded to treatment with cefepime plus amikacin. to our knowledge, this is the first report of metallo-beta-lactamase production in a ...201019624511
980-nm laser diode and treatment of subcutaneous mass in proteus-like syndrome. 201019627404
detection of ampc beta-lactamases in escherichia coli, klebsiella spp., salmonella spp. and proteus mirabilis in a regional clinical microbiology laboratory.there are currently no standardized diagnostic tests available for the reliable detection of ampc beta-lactamases in klebsiella spp., escherichia coli, proteus mirabilis and salmonella spp. a study was designed to evaluate a confirmation disk test using cefotetan (ctt) and cefoxitin (fox) with phenylboronic acid (pba). it also investigated the most suitable screening concentrations of fox, ceftriaxone (cro) and ceftazidime (caz) for the detection of ampc beta-lactamases. a total of 126 control ( ...201019456838
prevalence of acquired ampc beta-lactamases in enterobacteriaceae lacking inducible chromosomal ampc genes at a spanish hospital from 1999 to 2007.in 2007, a significant increase in acquired ampc genes in enterobacteriaceae from 0.06% in 1999 to 1.3% was observed. proteus mirabilis showed the highest prevalence (0.95%) and cmy-2 was the most prevalent ampc enzyme (66.7%). other enzymes such as cmy-4, dha-1, acc-1, and three new enzymes called cmy-25, cmy-27 and cmy-40 were detected. seven out of the 117 isolates (6%) also produced an extended-spectrum beta-lactamase. as acquired ampc enzymes are likely to become a serious public health iss ...201019523051
molecular analysis of intestinal microbiota of rainbow trout (oncorhynchus mykiss).the aim of this study was to evaluate different molecular tools based on the 16s rrna gene, internal transcribed spacer, and the rpob gene to examine the bacterial populations present in juvenile rainbow trout intestines. dna was extracted from both pooled intestinal samples and bacterial strains. genes were pcr-amplified and analysed using both temporal temperature gradient gel electrophoresis (ttge) and restriction fragment length polymorphism methods. because of the high cultivability of the ...201019780831
mastoid subperiosteal abscess as a first sign of unnoticed cholesteatoma in children.to present children who underwent mastoidectomy for congenital cholesteatoma presented as a subperiosteal abscess.201019814752
monozygotic twins discordant for vascular malformations and dysregulated growth.there is a large group of disorders characterized by non-cranial vascular malformations and a dysregulated growth, of which the prototype may be klippel-trenaunay syndrome (kts). the aetiology of kts and vascular malformations-dysregulated growth (vm-dg) syndromes resembling kts is obscure, but polygenic paradominant inheritance involving mutations or polymorphisms in two or more genes simultaneously, of which one (or more) are involved in (lymph)angiogenesis and the other(s) in growth regulatio ...201019716450
gram-negative bacteria associated with brewery yeasts: reclassification of obesumbacterium proteus biogroup 2 as shimwellia pseudoproteus gen. nov., sp. nov., and transfer of escherichia blattae to shimwellia blattae comb. nov.phylogenetic analyses of type and reference strains of obesumbacterium proteus biogroups 1 and 2 plus a novel isolate of biogroup 2 were carried out based on 16s rrna gene sequences and partial sequences of four protein-coding genes (fusa, leus, pyrg and rpob). both approaches revealed that o. proteus biogroup 1 strains were closely related to hafnia alvei. biogroup 2 strains, however, formed a distinct monophyletic clade of generic status that included escherichia blattae. phenotypic tests were ...201019661513
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