Publications

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antimicrobial properties of the stem bark of saraca indica (caesalpiniaceae).chloroform, methanol, aqueous and ethanolic extracts of the stem bark of saraca indica were investigated for their antibacterial and antifungal activity against standard strains of staphylococcus aureus, escherichia coli, pseudomonas aeruginosa, bacillus cereus, klebsiella pneumoniae, proteus mirabilis, salmonella typhimurium and streptococcus pneumoniae and the fungi: candida albicans and cryptococcus albidus. methanolic and aqueous extract exhibited antimicrobial activity with mic ranging from ...200919961043
electrostatic binding of substituted metal phthalocyanines to enterobacterial cells: its role in photodynamic inactivation.the effect of ionic substituents in zinc and aluminum phthalocyanine molecules and of membrane surface charge on the interaction of dyes with artificial membranes and enterobacterial cells, as well as on photosensitization efficiency was studied. it has been shown that increasing the number of positively charged substituents enhances the extent of phthalocyanine binding to escherichia coli cells. this, along with the high quantum yield of singlet oxygen generation, determines efficient photodyna ...200919961410
[enteropathogens relating to diarrhea in hiv patients on antiretroviral therapy].the etiology of the diarrheic process in aids may be caused by viruses, bacteria, fungi, protozoa or helminths, as well as hiv itself. this study evaluated enteropathogens relating to diarrhea in hiv patients who were on antiretroviral therapy. the parasitological methods used were faust, hoffmann and kinyoun. isolation and culturing of fungi were carried out in accordance with the methodology recommended by the nccls m27-a standard. the yeast species were identified using the polymerase chain r ...200919967238
effect of ibicella lutea on uropathogenic proteus mirabilis growth, virulence, and biofilm formation.proteus mirabilis, an important uropathogen that can cause complicated urinary tract infections (uti), has emerged as a therapeutic problem following mutations that compromise the use of antimicrobial drugs. due to the serious effects associated with uropathogenic p. mirabilis and the problems related to the use of antibiotics, it is necessary to develop alternative strategies for its control. the objective of this study was to assess the effect of ibicella lutea extract, a south american indige ...200920009277
[local control treatment of bacteria found present in an infected bed sore by means of a hydropolymer dressing with ionic silver].every chronic wound has microorganisms present on its surface and therefore, its contamination is universal and unavoidable, but the majority of these wounds are not infected. it is important, therefore, to refine the diagnosis of infection indentifying the microorganisms which have succeeded in gaining access to the submarginal tissues in order to be able to prevent unnecessary or inappropriate antibiotic treatment and to lessen possible complications. a high level of bacteria present, close to ...200920014620
nosocomial infections prevalence study in a serbian university hospital.nosocomial infections (ni) are a serious health problem resulting in an enromous burden of excess morbidity and mortaliti rates, and health care costs. the aim of this study was to assess the prevalence of ni and to identify groups of patients at special risk for ni in the university clinical center, kragujevac, serbia.200920017416
microbiological findings in prepubertal girls with vulvovaginitis.the aim of the study was to define the most common causes, symptoms and clinical features of vulvovaginitis in prepubertal girls, and to evaluate treatment success depending on the causative agent involved. the study included 115 girls aged 2-8 (mean 4.8) years, presenting with vulvovaginitis to the outpatient clinic for pediatric and adolescent gynecology, zagreb children's hospital, between september 2006 and july 2007. medical history data were obtained from parents. vaginal samples were coll ...200920021979
the influence of omentectomy on bacterial clearance: an experimental study.the influence of an omentectomy on peritoneal defense mechanisms and its clinical consequences have not been fully elucidated. in the present study, we aimed to investigate the influence of omentectomy on bacterial growth in blood and tissue specimen cultures in rats with experimental peritonitis.200920037870
[antimicrobial treatment of nosocomial intra-abdominal infections--new treatment options with tygecycline].nosocomial, intra-abdominal infections are extremely serious conditions, considering possibilities for their early diagnosis, as well as for their effective therapy. multiresistant bacteria (enterobacteriacae producing extended-spectrum beta-lactamases - esbl escherichia coli, klebsiella species, vancomycin-resistant enterococci [vre], and methicillin-resistant staphylococcus aureus [mrsa]) are frequently isolated as pathogens of these infections. tygecycline is among the novel wide- spectrum an ...200920052927
intra/extracellular biosynthesis of silver nanoparticles by an autochthonous strain of proteus mirabilis isolated from photographic waste.there is an enormous interest in developing green synthesis procedures for production of nanoparticles by using biomimetic approaches. in our research focus has been given to the development of an efficient and eco-friendly viable process for the synthesis of nanoscale silver particles using proteus mirabilis ptcc 1710, a bacterial strain that was isolated during a screening program from photographic waste. a significant result of this study is our observation that silver nanoparticles could be ...200920055006
bacteriological evaluation of pre-cut fruits sold in kano metropolis, kano state, nigeria.one hundred and fifty (150) pre-cut fruit samples comprising of pineapples (50), paw-paw (50) and watermelon (50) at the point of stand retail outlets were tested by standard bacteriological methods to determine bacterial contamination of the fruits. out of these 150 examined 136 (90.67%) were contaminated with bacteria. the bacterial distribution were; escherichia coli 69 (46.00%), staphylococcus aureus 29 (19.33%), salmonella species 13 (8.67%), proteus species 18 (12.00%), enterobacter aeroge ...200920000065
antimicrobial resistance patterns of staphylococcus aureus and proteus spp. isolated from otitis media at bahir dar regional laboratory, north west ethiopia.otitis media is a major health problem of children in low income countries like ethiopia. thus, this study was aimed at determining the predominant bacterial isolates from discharging ear and their antimicrobial susceptibility patterns.200920067141
[investigation of antibacterial activity of sertralin].sertralin is a psychotropic drug which acts by inhibiting the selective serotonin re-uptake in the synaptic area. previous studies have shown that some antidepressant agents have antibacterial activity. the aim of this study was to investigate the in vitro antibacterial activity of sertralin. a total of 224 bacterial strains isolated from clinical specimens together with standard control strains were included to the study. the antibacterial activity of sertralin was determined by microdilution m ...200920084919
antibacterial and antioxidant activities of the essential oil of artemisia echegarayi hieron. (asteraceae).artemisia echegarayi hieron. (asteraceae) is commonly known in argentina as "ajenjo". many studies report high efficacy of essential oils against food-borne pathogenic bacteria. the antimicrobial activity and minimal inhibitory concentration of a. echegarayi essential oil were evaluated against seven bacterial species of significant importance in food hygiene, by using the disc diffusion assay and the micro-well dilution method, respectively. volatile components of the extract were analyzed by g ...200920085186
[etiological factors of community acquired urinary tract infections in hospitalized patients].etiological factors of community-acquired urinary tract infections (uti) are specific for age, gender, season, complication of uti and type of uti. their prevalence and susceptibility to antimicrobial agents shows geographic and time variability.200920088156
assessment of microbiological quality of sachet-packaged drinking water in western nigeria and its public health significance.to assess the microbiological quality of sachet-packaged drinking water in western nigeria and its impact on public health.200919880150
notes on the microbiology of cholesteatoma: clinical findings and treatment.anomalous proliferation of the cholesteatoma epithelium is caused by extrinsic factors such as toxins or bacterial antigens combined with lytic enzymes, lymphokines and cytokines released from the inflammatory infiltrate. this could explain the close relationship between the aggressiveness of cholesteatoma and repeated bacterial superinfection, therefore it is very important to know the bacteria involved in order to control the regrowth of skin following surgery, reduce the aggressive potential ...200920161877
microbial evaluation and deterioration of paints and paint-products.the microbial quality of materials and final products of a reputable paint industry in lagos area were analysed. the bacterial contaminants isolated in the paint-products included bacillus brevis, b. polymyxa, b. laterosporus, lactobacillus gasseri, l. brevis, escherichia coli and proteus mirabilis. the fungal contaminants detected in the paints were mainly aspergillus niger, a. flavus and penicillium citrinum. the microbial populations in the raw materials ranged from 1.0 x 10(6) - 9.5 x 10(6) ...200920143715
resistances of antibiotics and heavy metals in enterobacteriaceae spp. isolated from gills and intestines of achanthobrama marmid (heckel,1843) from sir dam lake turkey.a total of 94 bacteria, associated with wild achanthobrama marmid (heckel, 1843) in sir dam lake of turkey identified. subsequently selected isolates were characterized and identified to the genus level the 94 members of enterobacteriaceae were isolated in the gills and intestines, and among the isolates, e. coli were represented at a rate of 55%, shigella spp. at a rate of 21%, salmonella spp. at a rate of 9%, citrobacter spp. at a rate of 9%, klebsiella spp. at a rate of 3% and proteus spp., a ...200920112859
pathogen incidence and antibiotic resistance patterns of catheter-associated urinary tract infection in children.the aim of this study was to characterize the pathogens and their antibiotic susceptibilities in children with catheter-associated urinary tract infection (cauti) in order to optimize empirical antibiotic therapy and prophylaxis. from 2001 to 2006, 895 children with an indwelling catheter from 3 hospitals in china were included in this study, of whom 335 (37.4%) had cauti. antimicrobial susceptibility testing of 450 bacterial isolates was performed using the clsi broth and kirby-bauer agar dilut ...200920071290
use of the cefepime-clavulanate esbl etest for detection of extended-spectrum beta-lactamases in ampc co-producing bacteria.extended-spectrum beta-lactamases (esbls) may not always be detected in routine susceptibility tests. this study reports the performance of the cefepime-clavulanate esbl etest for the detection of esbls in enterobacteriaceae, including those producing ampc enzyme.200920130375
[isolation and characterization of shewanella spp. from patients of food poisoning].to identify the isolates of shewanella spp. from specimens of food poisoning based on biological and biochemical analysis.200920193210
[susceptibility of enterobacteriaceae rods to selected tetracyclines].the aim of this study was to evaluated the susceptibility of enterobacteriaceae rods to tigecycline, tetracycline and doxycycline. we analysed 121 strains belonged to species as follows: escherichia coli (40 strains), proteus mirabilis (22), enterobacter cloacae (19), klebsiellapneumoniae (18), morganella morgannii (13), serratia marcescens (4), klebsiella oxytoca (3) i proteus vulgaris (2). all strains of e. coli, k. oxytoca, s. marcescens and p. vulgaris were susceptible to tigecycline. twenty ...200920201321
risk factors for hospital-acquired pneumonia in nonventilated adults.although most recent publications focus on ventilator-associated pneumonia, non-ventilator-associated hospital-acquired pneumonia (nvhap) is still worrisome. we studied risk factors for nvhap among patients admitted to a small teaching hospital. sixty-six nvhap case patients and 66 controls admitted to the hospital from november 2005 through november 2006 were enrolled in a case-control study. variables under investigation included: demographic characteristics, comorbidities, procedures, invasiv ...200920231992
extended spectrum beta-lactamase detection in gram-negative bacilli of nosocomial origin.resistance to third generation cephalosporins by acquisition and expression of extended spectrum beta lactamase (esbl) enzymes among gram-negative bacilli is on a rise. the presence of esbl producing organisms significantly affects the course and outcome of an infection and poses a challenge to infection management worldwide.200920300397
increasing resistance to quinolones: a four-year prospective study of urinary tract infection pathogens.a four-year prospective study was carried out to determine the incidence and rate of development of resistance by common urinary tract infection (uti) pathogens to quinolone antimicrobial agents. results show that there is high intrinsic resistance to the quinolones among strains of pseudomonas aeruginosa (43.4%), escherichia coli (26.3%), and proteus spp. (17.1%). over four years, rising rates of resistance were observed in p. aeruginosa (14.6% increase), staphylococcus aureus (9.8%), and e. co ...200920360901
proteus vertebral osteomyelitis.proteus organisms are rare causes of osteomyelitis. vertebral osteomyelitis caused by this organism has only been reported in 21 cases over the last 75 years. although staphylococcus aureus is the most common cause of vertebral osteomyelitis, rare causes such as p. mirabilis may need to be considered in the context of recent urinary tract infection or urological surgery. therefore biopsy should be undertaken to establish the causative organism and determine appropriate antibiotic susceptibility.200920374334
health assessment of a spiny-tailed lizard (uromastyx spp.) population in abu dhabi, united arab emirates.a study was conducted to determine the health status of the free-living spiny-tailed lizard (uromastyx spp.) population at wrsan, al ajban, abu dhabi, united arab emirates. a total of 90 spiny-tailed lizards, 61 males and 29 females, were examined from june to august 2006. mean body weights were 1,564.4 g and 809.4 g for males and females, respectively. mean body lengths were 62.1 cm and 49.4 cm for males and females, respectively. fourteen lizards were found with abnormalities including abscess ...200919746858
effective strategies for prevention and control of gram-negative infections.infections caused by gram-negative bacteria such as pseudomonas, klebsiella, proteus and acinetobacter have been a major problem in healthcare settings for many years. overlooked in government targets and unknown to patients, these infections present considerable challenges for effective infection prevention and control. key strategies for prevention and control focus on contact precautions, the management of invasive devices and maintaining a clean, dry environment to prevent the build-up of en ...200919753872
isolation of salmonella and shigella from fish harvested from the winam gulf of lake victoria, kenya.human infections caused by pathogens transmitted from fish are quite common. the aim of this study was to isolate enteric pathogenic bacteria from fish that might be transmitted to humans after the handling or consumption of such fish.200919755738
the role of tyrosine kinases in water-electrolyte transport in amoeba a. proteus. 200919760870
invasive bacteria isolates from children with severe infections in a nigerian hospital.little information is available about the aetiology and epidemiology of serious bacterial infections in nigeria. this study determined bacterial isolates from blood and cerebrospinal fluid (csf) of children presenting in the emergency room of a teaching hospital in nigeria.200919762955
tryptophan inhibits proteus vulgaris tnac leader peptide elongation, activating tna operon expression.expression of the tna operon of escherichia coli and of proteus vulgaris is induced by l-tryptophan. in e. coli, tryptophan action is dependent on the presence of several critical residues (underlined) in the newly synthesized tnac leader peptide, wfnidxxl/ixxxxp. these residues are conserved in tnac of p. vulgaris and of other bacterial species. tnac of p. vulgaris has one additional feature, distinguishing it from tnac of e. coli; it contains two c-terminal lysine residues following the conser ...200919767424
[ability of opportunistic enterobacteria to adapt to different temperatures].to study variability of enzymatic apparatus of opportunistic enterobacteria.200919459471
antimicrobial activity of selected plant species from "the argentine puna" against sensitive and multi-resistant bacteria.the plant species reported here are traditionally used in the "puna" or "altiplano" of argentina for ailments related to bacterial infections. the aim of this study was to evaluate their antimicrobial properties against a panel of sensitive and multi-resistant gram-positive and gram-negative bacteria.200919467313
the effect of edta instillations on the rate of development of encrustation and biofilms in foley catheters.the aim of this research was to examine whether a daily instillation of tetra sodium ethylenediaminetetraacetic acid (edta) solution could reduce the rate at which encrustation by crystalline proteus mirabilis biofilms blocks urinary catheters. sets of three bladder models were fitted with size 14 all-silicone catheters. tetra sodium edta solution was instilled into the catheter following biofilm development. catheters were examined by digital photography and scanning electron microscopy for evi ...200919468723
orbital cellulitis and endogenous endophthalmitis secondary to proteus mirabilis cholecystitis.we report the first case of orbital cellulitis and endogenous endophthalmitis secondary to proteus mirabilis bacteremia that resulted from a calculus cholecystitis. despite resolution of the gallbladder infection with antimicrobial therapy, the patient required evisceration of the affected eye. the pathogenesis of hematogenous endophthalmitis due to gram-negative bacilli is discussed.200919631098
synthesis and antibacterial activities of new metronidazole and imidazole derivatives.new imidazole ring derivatives comprising 1,3-oxazoline, schiff's bases, thiadiazole, oxadiazole and 1,2,4-triazole moieties are reported. 3-aminobiimidazol-4-one compounds 7a-c were synthesized by the reaction of compounds 6a-c with hydrazine hydrate. biimidazole esters 9a-c were converted into biimidazole hydrazide esters 10a-c. compounds 7a-c and 10a-c were converted into a variety of derivatives.200919633614
paracin 1.7, a bacteriocin produced by lactobacillus paracasei hd1.7 isolated from chinese cabbage sauerkraut, a traditional chinese fermented vegetable food.to purify and characterize bacteriocin produced by l. paracasei hd1.7.200919637568
a novel antimicrobial peptide from crotalaria pallida seeds with activity against human and phytopathogens.an actual severe problem in agriculture consists of an expressive increase of economical losses caused by fungi and resistant bacteria toward antibiotics. in order to find a solution to this problem, several studies have been concentrating on the screening of novel plant defense peptides with antimicrobial activities. these peptides are commonly characterized by having low molecular masses and cationic charges. the present work reports the purification and characterization of a novel plant pepti ...200919641962
depression, cortisol, and suppressed cell-mediated immunity in metastatic breast cancer.cancer treatment is known to have significant immuno-suppressive/dysregulatory effects. psychological distress and depression, which often accompany cancer diagnosis and treatment, can also suppress or dysregulate endocrine and immune function. cell-mediated immunity (cmi) is critical for protection against a host of pathogens to which cancer patients may be particularly susceptible. cmi is also important for defense against some tumors. this study explored relationships among depressive symptom ...200919643176
n-(1-carboxyethyl)alanine (alanopine), a new non-sugar component of lipopolysaccharides of providencia and proteus.o-polysaccharides were released by mild acid degradation of lipopolysaccharides of providencia alcalifaciens o35 and proteus vulgaris o76 and were studied by 1d and 2d (1)h and (13)c nmr spectroscopies, including hmbc and noesy (roesy) experiments. both polysaccharides were found to contain n-(1-carboxyethyl)alanine (alanopine) that is n-linked to 4-amino-4,6-dideoxyglucose. analysis of published data [vinogradov, e.; perry, m. b. eur. j. biochem.2000, 267, 2439-2446] shows that alanopine is pre ...200919651402
phenotypic characterization of human pathogenic bacteria in fish from the coastal waters of south west cameroon: public health implications.increasing economic and recreational opportunities, attractive scenery and a perception of a better quality of life are luring people to the coast. unfortunately, these activities together with the commensurate increase in population in the area inevitably result in pollution of coastal waters with excessive microorganisms and other pollutants. microbial pollutants not only contaminate the coastal water but also aquatic food sources, thus posing a health risk to consumers. fish is a major source ...200919658320
research of urinary tract infections in family medicine physicians' offices--empiric antimicrobial therapy of urinary tract infections--croatian experience.in the period between october 1st and november 30th, 2006, we investigated a total of 3188 episodes of uti (802 among males; 2386 among females) recorded in 108 family medicine offices in 20 cities in croatia. the most common utis in women were acute uncomplicated cystitis (62%), complicated utis - cystitis and pyelonephritis (14%), urethritis (9%), acute uncomplicated pyelonephritis (6%), recurrent cystitis (5%), asymptomatic bacteriuria (3%) and recurrent pyelonephritis. the most common utis i ...200919662789
pten hamartoma tumor syndrome: an overview.pten hamartoma tumor syndrome (phts) encompasses four major clinically distinct syndromes associated with germline mutations in the tumor suppressor pten. these allelic disorders, cowden syndrome, bannayan-riley-ruvalcaba syndrome, proteus syndrome, and proteus-like syndrome are associated with unregulated cellular proliferation leading to the formation of hamartomas. thus far, an increased risk of malignancy has only been documented in cowden syndrome; however, current recommendations advise th ...200919668082
frequency and antimicrobial susceptibility of gram-negative bacteria isolated from 2 hospitals in makkah, saudi arabia.to estimate the prevalence and antibiotic susceptibility of the gram-negative bacteria isolated from 2 hospitals in makkah.200919668881
predictors of primary breast abscesses and recurrence.we investigated the patients and microbiological risk factors that predispose to the development of primary breast abscesses and subsequent recurrence.200919669231
isolation and characterization of new metschnikowia pulcherrima strains as producers of the antimicrobial pigment pulcherrimin.metschnikowia pulcherrima is a highly effective biocontrol yeast due to its pigment pulcherrimin that accumulates in the cells and in the growth medium. three different strains of m. pulcherrima were isolated from local grapes. the yeast isolates were characterized on the basis of their biochemical, physiological and its1-5.8 s rdna-its2 region. based on the obtained results, the m. pulcherrima isolates were identified as new strains of m. pulcherrima. strong antagonistic activities of the m. pu ...200919678547
significance of cytomorphological and microbiological examination of bile collected by endoscopic cannulation of the papilla of vater.bile analysis yields important information such as "biliary microlithiasis" and biliary tract colonization by microorganisms like salmonella typhi or paratyphi, escherichia coli, etc., which may progresses to cholelithiasis and have been found to have a role in the development of gallbladder cancer in india.200919679953
[evaluation of apoptosis expression in granulation tissue in chronic otitis media].there is a growing evidence that molecular and cellular mechanisms may play a role in pathogenesis in chronic otitis media.200919681486
[a very extensive necrotizing fasciitis].necrotizing fasciitis is a severe skin infection. fluidized bed may be indicated to improve healing. we report a 36-year-old woman case, who developed an important skin emphysema on a fluidized bed that may have worsen the situation.200919682835
identification of a modular pathogenicity island that is widespread among urease-producing uropathogens and shares features with a diverse group of mobile elements.pathogenicity islands (pais) are a specific group of genomic islands that contribute to genomic variability and virulence of bacterial pathogens. using a strain-specific comparative genomic hybridization array, we report the identification of a 94-kb pai, designated icepm1, that is common to proteus mirabilis, providencia stuartii, and morganella morganii. these organisms are highly prevalent etiologic agents of catheter-associated urinary tract infections (cauti), the most common hospital acqui ...200919687197
bacteria isolated from 25 hydatid cysts in sheep, cattle and goats.bacteria were isolated from 12 of 25 hydatid cysts collected from the lungs and livers of cattle, sheep and goats slaughtered in the province of messina, sicily, italy. citrobacter freundii was isolated from seven of the cysts, aeromonas hydrophila from three, staphylococcus species from two, salmonella species from two and escherichia coli and proteus vulgaris from one.200919700784
comparison study of membrane filtration direct count and an automated coliform and escherichia coli detection system for on-site water quality testing.this study compared an automated escherichia coli and coliform detection system with the membrane filtration direct count technique for water testing. the automated instrument performed equal to or better than the membrane filtration test in analyzing e. coli-spiked samples and blind samples with interference from proteus vulgaris or aeromonas hydrophila.200919703500
macrocephaly-capillary malformation: a report of three cases and review of the literature.macrocephaly-cutis marmorata telangiectatica congenita (m-cmtc) is a rare syndrome that was first delineated as distinct from cutis marmorata telangiectatica congenita (cmtc) in 1997. since that time, there have been over 75 cases reported in the literature, though few are in the dermatology literature. the syndrome is characterized by macrocephaly, neonatal hypotonia, developmental delay, segmental overgrowth, syndactyly, asymmetry, connective tissue defects, and vascular stains. we report thre ...200919706101
human complement activation by smooth and rough proteus mirabilis lipopolysaccharides.proteus mirabilis bacilli play an important role in human urinary tract infections, bacteremia, and rheumatoid arthritis. the authors previously studied human complement c3 conversion by smooth-form p. mirabilis o10, o23, o30, and o43 lipopolysaccharides (lpss) and showed that smooth proteus lpss fragmented c3 in a dose- and time-dependent manner. in the present study, one smooth p. mirabilis s1959 and its two polysaccharide-truncated lpss isolated from an r mutant strain were used to study the ...200919707721
a novel isoquinoline alkaloid, dd-carboxypeptidase inhibitor, with antibacterial activity isolated from streptomyces sp. 8812. part i: taxonomy, fermentation, isolation and biological activities.a novel isoquinoline alkaloid of molecular formula c10h9no4, labeled js-1, was isolated from the culture broth of streptomyces sp. 8812. it was purified by acetone protein precipitation from the culture supernatant, followed by anion exchange and c18 rp hplc columns. js-1 is an inhibitor of exocellular dd-carboxypeptidases/transpeptidases (dd-peptidases) 64-575 ii from saccharopolyspora erythraea 64-575 ii, and r39 from actinomadura r39. js-1 exhibits activity against gram-negative bacteria, suc ...200919713994
effects of the administration of cholera toxin as a mucosal adjuvant on the immune and protective response induced by proteus mirabilis mrpa fimbrial protein in the urinary tract.proteus mirabilis is commonly associated with complicated uti and expresses several virulence factors, including mr/p fimbriae. in the present study mice were immunised nasally with mrpa, the structural subunit of mr/p, with or without ct as a mucosal adjuvant. the animals were then challenged with p. mirabilis and induction of specific serum and urine igg and iga, ifn-gamma production and bacterial kidney and bladder colonization were assessed. mrpa-immunised mice exhibited significant inductio ...200919714860
[the autoagglutination factor of plague pathogen--cross-reacting antigen].an antigen similar to the autoagglutination factor (af) of plague pathogen in immunochemical specificity was sought in 22 bacterial species. for this, an immunoglobulin anti-af diagnosticum that is the sheep erythrocytes sensitized with rabbit immune serum to the af preparation isolated from the plasmid-free variant of the yersinia pestis strain ev76. the bacteriological study applying a passive hemagglutination assay revealed af-like antigens not only in all study strains (n = 30) of y. pestis, ...200919718822
complex combined vascular malformations and vascular malformation syndromes affecting the extremities in children.complex combined vascular malformations affecting extremities are an interesting group of vascular malformations because, in addition to the vascular channel anomalies present, they can be associated with other tissue changes and sometimes altered limb growth. at present, magnetic resonance imaging is the gold standard imaging tool to evaluate such complex conditions in children because of its inherent tissue specificity and vascular capabilities that enables characterization of tissues and the ...200919724993
proteomic analysis of a matrix stone: a case report.matrix stones are radiolucent bodies that present as soft muco-proteinaceous material within the renal collecting system. following wide-angle x-ray diffraction (xrd) and scanning electron microscopy (sem), we homogenized a surgically removed matrix stone, extracted and purified protein, and analyzed samples using tandem mass spectrometry for proteomic composition. resulting spectra were searched using proteinpilot 2.0, and identified proteins were reported with >95% confidence. primary xrd mine ...200919730843
coumestan glycosides from the stem bark of cylicodiscus gabunensis.two new coumestan glycosides, coumestoside c (1) and coumestoside d (2), were isolated from the stem bark of cylicodiscus gabunensis harms. their structures were established by spectroscopic means and chemical transformations as 9-o-alpha-l-rhamnopyranosyl-3-hydroxy-4-(5'-hydroxy-3'-methylbut-2'e-enyl) coumestan (1) and 9-o-beta-d-galactopyranosyl-3-o- prenyl-4-hydroxycoumestan. coumestoside c exhibited antimicrobial activity against proteus vulgaris.200919731596
sudden death and the forensic evaluation of neurocutaneous syndromes.on occasion the forensic evaluation of individuals who have died suddenly and unexpectedly may reveal intracranial vascular abnormalities such as capillary, venous- and arteriovenous malformations. such vascular abnormalities may form part of a heterogeneous group of disorders called neurocutaneous syndromes and involve the skin, nervous system and other organ systems. these unusual conditions include sturge-weber, osler-weber-rendu, klippel-trenaunay, von hippel-lindau, proteus and wyburn-mason ...200919733322
in vitro activity of nemonoxacin, a novel nonfluorinated quinolone, against 2,440 clinical isolates.the in vitro activity of nemonoxacin (tg-873870), a novel nonfluorinated quinolone, was tested against 2,440 clinical isolates. nemonoxacin was at least fourfold more active than levofloxacin and moxifloxacin against most gram-positive cocci tested (shown by the following mic(90)/range [microg/ml] values; community-associated methicillin [meticillin]-resistant staphylococcus aureus, 0.5/0.015 to 2; staphylococcus epidermidis, 0.5/0.015 to 4 for methicillin-susceptible staphylococci and 2/0.12 to ...200919738018
extended-spectrum beta-lactamases among enterobacteriaceae isolated in a public hospital in brazil.extended-spectrum beta-lactamases (esbl) in enterobacteria are recognized worldwide as a great hospital problem. in this study, 127 esbl-producing enterobacteriaceae isolated in one year from inpatients and outpatients at a public teaching hospital at são paulo, brazil, were submitted to analysis by pcr with specific primers for bla shv, bla tem and bla ctx-m genes. from the 127 isolates, 96 (75.6%) klebsiella pneumoniae, 12 (9.3%) escherichia coli, 8 (6.2%) morganella morganii, 3 (2.3%) proteus ...200919739000
proteus syndrome: a case report.proteus syndrome is a rare, sporadically occurring hamartomatous disorder with complex multisystem involvement and wide clinical variability. clinical characteristics include craniofacial abnormalities; asymmetrical overgrowth of the trunk, limbs, and digits; lipomas; and vascular malformations. cystic lung disease is noted in approximately 10 per cent of patients. these cystic malformations may lead to cystic pulmonary emphysema, which may cause significant morbidity for the patient. we describ ...200919774961
bactericidal activity in filtrated supernatant of streptococcus sanguinis against multidrug-resistant pseudomonas aeruginosa.in the past decade, multidrug-resistant pseudomonas aeruginosa (mdrp) infection has become a serious clinical problem, due to the limitation of drug choices to fight against the bacteria. here we explored the bactericidal activity in the filtrated supernatant of streptococcus (s.) sanguinis against pseudomonas (p.) aeruginosa. s. sanguinis is one of the alpha-hemolytic streptococci that commonly reside in the human oral cavity. a strain of s. sanguinis, isolated from the sputum of a pulmonary-di ...200919776523
bacteriology of external ocular infections in aba, south eastern nigeria.bacteria are microbial agents that frequently cause infections of the eye and possible loss of vision.200919780761
chemical compositions and antibacterial activities of the essential oils from aerial parts and corollas of origanum acutidens (hand.-mazz.) ietswaart, an endemic species to turkey.essential oils extracted by hydrodistillation from the aerial parts and corollas of origanum acutidens (hand.-mazz.) ietswaart, an endemic turkish flora species, were analyzed by gc-ms. the amounts of essential oil obtained from the aerial parts and the corollas were 0.73% and 0.93%, respectively. twenty-five components in both the aerial parts oil and the corolla oil, representing 95.11% and 93.88%, respectively, were identified. the aerial parts and corolla oils were characterized by the predo ...200919471191
antibiotic resistance of gram negatives isolates from loggerhead sea turtles (caretta caretta) in the central mediterranean sea.previous studies on fish and marine mammals support the hypothesis that marine species harbor antibiotic resistance and therefore may serve as reservoirs for antibiotic-resistance genetic determinants. the aim of this study was to assess the resistance to antimicrobial agents of gram negative strains isolated from loggerhead sea turtles (carettacaretta). oral and cloacal swabs from 19 live-stranded loggerhead sea turtles, with hooks fixed into the gut, were analyzed. the antimicrobial resistance ...200919473669
incidence of multiple antibiotic resistant gram-negative bacteria isolated from surface and underground water sources in south western region of nigeria.in most rural and urban settlements, particularly in nigeria, wells, spring, streams or rivers and lakes serves as major sources of water supply for drinking and other domestic purposes. unfortunately, many of the available water sources are not potable without some form of treatment which is seldom available in most settings. the use of untreated surface water sources for drinking and for domestic purposes remains a major threat to public health as these could serve as reservoirs the for transf ...200919474486
design and quality control of a pharmaceutical formulation containing natural products with antibacterial, antifungal and antioxidant properties.the aims of the present study were to determine the antibacterial and antifungal activity as well as mutagenicity of sechium edule fluid extract and to obtain a pharmaceutical formulation with them. the extract exhibited antimicrobial activity against escherichia coli, klebsiella pneumoniae, proteus mirabilis, enterobacter cloacae, serratia marcescens, morganella morganii, acinetobacter baumannii, pseudomonas aeruginosa, stenotrophomonas maltophilia, candida spp. and aspergillus spp. isolated fr ...200919477252
rheumatoid arthritis is caused by proteus: the molecular mimicry theory and karl popper.rheumatoid arthritis is a crippling and disabling joint disease affecting over 20 million people. it occurs predominantly in women and smokers, and affects the hla-dr1/4 individuals who carry the "shared epitope" of amino acids eqrraa. the cause of this disease was investigated by the methods of the philosopher of science karl popper who suggested that scientific research should be based on bold conjectures and critical refutations. the "popper sequences" generate new facts which then change or ...200919482674
an appraisal of current management of childhood urinary tract infections among private medical practitioners.private medical practitioners manage substantial number of children with urinary tract infection in nigeria. it is important to evaluate the management of urinary tract infection (uti), because of complications that may arise form improper treatment.200919485147
dependence of swarming in escherichia coli k-12 on spermidine and the spermidine importer.in a previous work, it was observed that the swarming of polyamine-deficient proteus mirabilis (speb::sm) was severely inhibited on luria-bertani (lb) swarming plates (lbsw) (lb, 0.5% glucose, 0.5% agar), and it was clarified that extracellular putrescine was important as a signaling molecule for the induction of swarming in p. mirabilis. however, a polyamine-deficient strain (delta-speab delta-spec) of escherichia coli swarmed as well as the parental strain on lbsw plates. we report that the sw ...200919493013
structural and functional studies of truncated hemolysin a from proteus mirabilis.in this study we analyzed the structure and function of a truncated form of hemolysin a (hpma265) from proteus mirabilis using a series of functional and structural studies. hemolysin a belongs to the two-partner secretion pathway. the two-partner secretion pathway has been identified as the most common protein secretion pathway among gram-negative bacteria. currently, the mechanism of action for the two-partner hemolysin members is not fully understood. in this study, hemolysis experiments reve ...200919494116
oral bacterial flora of the chinese cobra (naja atra) and bamboo pit viper (trimeresurus albolabris) in hong kong sar, china.to determine the oral bacterial flora associated with two common local venomous snakes in hong kong, namely the chinese cobra (naja atra) and the bamboo pit viper (trimeresurus albolabris).200919494373
[thoraco-brachial cystic lymphangioma and proteus syndrome: prenatal diagnosis and mr follow-up]. 200919503050
preparation, physicochemical characterization and biological evaluation of cefodizime metal ion complexes.cefodizime is a broad spectrum cephalosporin belonging to the third generation agents. in this study, attention has been paid to the preparation, physicochemical characterization and biological evaluation of new cu2+, zn2+, fe3+, co2+ and al3+ complexes of cefodizime.200919505365
the aresc study: an international survey on the antimicrobial resistance of pathogens involved in uncomplicated urinary tract infections.the aresc (antimicrobial resistance epidemiological survey on cystitis) study is an international survey to investigate the prevalence and susceptibility of pathogens causing cystitis. female patients (n=4264) aged 18-65 years with symptoms of uncomplicated cystitis were consecutively enrolled in nine european countries as well as brazil during 2003-2006. pathogens were identified and their susceptibility to nine antimicrobials was determined. escherichia coli accounted for 76.7% of isolates. am ...200919505803
are sinus-track cultures reliable for identifying the causative agent in chronic osteomyelitis?the infection of bone that contains bone marrow called osteomyelitis, and is caused by different microorganisms. in this study, we aimed to determine the diagnostic value and accuracy of cultures of material from a sinus track compared with those of cultures of bone specimens that have been controversial.200919513734
[evaluation of effectiveness and tolerance of treatment with azithromycin 1.5% eye drops in bacterial conjunctivitis].azithromycin is a macrolide class antibiotic, recently adapted for topical use in ophthalmology. it is effective against the most frequent pathogens found in bacterial conjunctivitis, gram positive and gram negative bacteria. azithromycin has the specificity to have sustained high tissue levels: after repeated instillation, it has been shown to reach sustained concentrations above the mics of susceptible bacteria for 4 days in tears and for 7 days in conjunctiva.200919517846
otogenic cerebellar abscess: a case report.this case report describes the gradual deterioration of a healthy, highly functioning man who initially presented with a draining right ear. the patient's indolent neurologic decline and referral to an otologist ultimately led to the diagnosis and treatment of an otogenic cerebellar abscess, an increasingly rare intracranial complication of otitis media. we report this case to illustrate that severe complications of chronic otitis media still occur in the united states, to stress the importance ...200919358116
proteus syndrome: report of a case with recurrent abdominal lipomatosis.proteus syndrome (ps) is an extremely rare congenital hamartomatous syndrome that was first delineated by cohen and hayden (1). the estimated prevalence is less than 1 per 1,000,000 live births (2). it is a sporadic disorder that causes overgrowth of multiple tissues, especially bone, fat, and other connective tissues in a patchy or mosaic pattern. subcutaneous as well as internal lipomas that may grow to an enormous size are frequently observed. nevertheless, among the internal lipomas, abdomin ...200919361616
[phosphatase activity in amoeba proteus at low ph].in free-living amoeba proteus (strain b), three forms of tartrate-sensitive phosphatase were revealed using page of the supernatant of ameba homogenates obtained with 1% triton x-100 or distilled water and subsequent staining of gels with 2-naphthyl phosphate as substrate (ph 4.0). the form with the highest mobility in the ameba supernatant was sensitive to all tested phosphatase activity modulators. two other forms with the lower mobilities were completely or significantly inactivated not only ...200919370987
the high-affinity phosphate transporter pst in proteus mirabilis hi4320 and its importance in biofilm formation.proteus mirabilis causes urinary tract infections (utis) in individuals requiring long-term indwelling catheterization. the pathogenesis of this uropathogen is mediated by a number of virulence factors and the formation of crystalline biofilms. in addition, micro-organisms have evolved complex systems for the acquisition of nutrients, including the phosphate-specific transport system, which has been shown to be important in biofilm formation and pathogenesis. a functional pst system is important ...200919372157
organisms associated with ventilator associated pneumonia in intensive care unit.it is a cross sectional observational study. place of study was the icu of square hospitals ltd. and icu of bangabandhu sheikh mujib medical university (bsmmu). all patients who were diagnosed as a case of ventilator associated pneumonia (vap) in icu during the one year study period (01.01.2006 to 31.12.2006) were included in this study. data was collected by patient's clinical register, checklist. total number of patients was 43. main objective of our study was to identify the organisms associa ...200919377438
overgrowth conditions: a diagnostic and therapeutic conundrum.over the past five decades, one of the major problems in the treatment of overgrowth syndromes of the hand has been classification. currently, a number of specific conditions with known natural histories have been delineated and reviewed. treatment is highly individualized. amputation is still recommended for grotesque deformities of the upper limb. early aggressive surgery, when indicated, will improve contour, function, and appearance. specific therapeutic techniques include radical debulking, ...200919380062
pseudomonas aeruginosa las quorum sensing autoinducer suppresses growth and biofilm production in legionella species.bacteria commonly communicate with each other by a cell-to-cell signalling mechanism known as quorum sensing (qs). recent studies have shown that the las qs autoinducer n-(3-oxododecanoyl)-l-homoserine lactone (3-oxo-c(12)-hsl) of pseudomonas aeruginosa performs a variety of functions not only in intraspecies communication, but also in interspecies and interkingdom interactions. in this study, we report the effects of pseudomonas 3-oxo-c(12)-hsl on the growth and suppression of virulence factors ...200919383702
in vitro biological activity screening of lycopodium complanatum l. ssp. chamaecyparissus (a. br.) doll.this article reports the results of selected biological activities, including anticholinesterase, antioxidant, antibacterial, antifungal and antiviral properties, of the petroleum ether, chloroform and methanol extracts as well as the alkaloid fraction of lycopodium complanatum l. ssp. chamaecyparissus (a. br.) doll (lcc, lycopodiaceae) growing in turkey. anticholinesterase effect of the extracts was tested against both acetylcholinesterase (ache) and butyrylcholinesterase (bche) at concentratio ...200919384728
verdoheme formation in proteus mirabilis catalase.heme oxidative degradation has been extensively investigated in peroxidases but not in catalases. the verdoheme formation, a product of heme oxidation which inactivates the enzyme, was studied in proteus mirabilis catalase.200919394409
cardiac tamponade caused by polymicrobial gram-negative organisms.polymicrobial gram-negative pericarditis is a rare entity. we describe the first case of suppurative pericarditis with citrobacter diversus and proteus mirabilis.200919395299
integration of pharmacokinetic and pharmacodynamic indices of orbifloxacin in beagle dogs after a single intravenous and intramuscular administration.the pharmacokinetics (pk) and pharmacodynamics (pd) of orbifloxacin were studied in beagle dogs after intravenous (i.v.) and intramuscular (i.m.) administration at a dose of 2.5 mg/kg body weight. an absolute bioavailability of 100.1% +/- 4.76%, a terminal half-life of 4.23 +/- 0.2 h and 3.95 +/- 0.15 h after i.v. and i.m. administration, a steady-state volume of distribution of 1.61 +/- 0.13 liters/kg, and clearance of 0.31 +/- 0.03 liters/h/kg were observed. orbifloxacin showed rapid, concentr ...200919398644
quinine is bactericidal.to determine the antibacterial properties of quinine dihydrochloride and its mic.200919402279
[effect of the drug-resistant attenuated bacillus proteus on cd80 and cd86 protein expression in peripheral blood dendritic cells of hepatitis b patients].to explore the effect of the drug-resistant attenuated bacillus proteus on the protein expression of cd80 and cd86 in peripheral blood dendritic cells (dcs) of hepatitis b patients.200919403426
tourniquets and exsanguinators: a potential source of infection in the orthopedic operating theater?fomites are increasingly being recognised as a source of hospital-acquired infection. we have therefore assessed tourniquets and exsanguinators for the presence of bacterial pathogens in 1 elective and 2 trauma orthopedic hospitals.200919404812
management of complicated infections in the era of antimicrobial resistance: the role of tigecycline.increasing antimicrobial resistance and infection complications pose challenges to optimal antibiotic therapy. paucity of new antibiotics (and the eventual bacterial resistance they face) highlights the critical need for more appropriate use of broadly effective agents, which may help to thwart the dramatic rise in global resistance. single agents that can be combined effectively with others, if needed, promise the simplest overall utility. approved in 2005 to treat complicated skin and intra-ab ...200919405794
piscidin 4, a novel member of the piscidin family of antimicrobial peptides.piscidins are linear, amphipathic, antimicrobial peptides (amps) with broad, potent, activity spectrum. piscidins and other members of the piscidin family appear to comprise the most common group of amps in teleost fish. all piscidins and related members of the piscidin family described to date are 18-26 amino acids long.we report here the isolation of a novel 5329.25 da, 44-residue (ffrhlfrgakaifrgarqgxrahkvvsryrnrdvpetdnnqeep) antimicrobial peptide from hybrid striped bass (morone chrysops fem ...200919266617
comparison of clinical symptoms scored according to the national institutes of health chronic prostatitis symptoms index and assessment of antimicrobial treatment in patients with chronic prostatitis syndrome.we examined a total of 194 patients over 18 years of age with chronic prostatitis syndrome and no evidence of structural or functional lower genitourinary tract abnormalities. the following data were obtained for each patient: clinical history--the severity of chronic prostatitis symptoms scored by a croatian translation of the nih cpsi questionnaire, clinical status including digitorectal examination, urethral swab specimens, and selective samples of urine and expressed prostatic secretion, acc ...200919423471
bacterial toxin higb associates with ribosomes and mediates translation-dependent mrna cleavage at a-rich sites.most pathogenic proteus species are primarily associated with urinary tract infections, especially in persons with indwelling catheters or functional/anatomic abnormalities of the urinary tract. urinary tract infections caused by proteus vulgaris typically form biofilms and are resistant to commonly used antibiotics. the rts1 conjugative plasmid from a clinical isolate of p. vulgaris carries over 300 predicted open reading frames, including antibiotic resistance genes. the maintenance of the rts ...200919423702
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