PMID(sorted ascending)
evaluation of a proteus rettgeri o-serotyping system for epidemiological evaluation of the serotyping system for proteus rettgeri has been performed through its application to 561 human isolates of this species. of these, 545 were typable and could be separated into 58 o serotypes. a group of isolates from one hospital, and clinically implicated in cross-infections, was found to belong the same o serotype, confirming the clinical findings. isolates with more than one specificity of thermostable antigen, in most cases, were found to have combinations of such specif ...197657120
letter: therapeutic use of peritoneal cells. 197658290
[bacterial fora of patients treated with bleomycin].microflora of the pharynx, nose, sputum and excrements was investigated. it was found that bleomycin therapy may induce or aggravate the shifts in microbiocenosis of the pharynx and sputum in the direction of pathogenization (increase in the number of staph. aureus, hemolytic streptococci, enterobacteria). a tendency to elimination of bifidobacteria and appearance of proteus in the excrements was observed. complications associated with the treatment are rarely of infectious origin.197658578
antigenic relationship between morganella morganii and yersinia enterocolitica.two new o antigens have been described for the morganella morganii antigenic schema. o antigens of the strains representing the new serotypes (o43 :h2 and o44 : h19, 37) are related to yersinia enterocolitica o9 and o17, respectively.197659520
immunochemical study of the peptidoglycan of gram-negative bacteria.the specificity of antibodies directed against the peptidoglycan of gram-negative bacteria was studied. the peptidoglycans of proteus vulgaris, escherichia coli, moraxella glucidolytica, neisseria perflava, give identical precipitin reactions. by means of inhibition studies with various peptidoglycan subunits and synthetic peptides, it was shown that the antibodies are essentially directed against the peptide moiety of the peptidoglycan: l-ala-d-glu (l)-mesoa2pm-(l)-d-ala, that the peptide react ...197660233
rational choice of penicillins and cephalosporins based on parallel in-vitro and in-vivo tests.because of the unavailability of strictly comparable data, seven representative penicillins and the five cephalosporins currently used in britain were evaluated in parallel, both in vitro and in vivo. penicillin sensitive and resistant strains of staphylococcus aureus and proteus mirabilis were the main test organisms. minimum bacteriocidal concentrations of cloxacillin, flucloxacillin, cephalothin, and cephazolin in serum were much higher than conventional minimum inhibitory concentrations in t ...197661353
"5-amino-5"-deoxybutirosin, a semisynthetic analogue of butirosin a: antibacterial activity in vitro and in mice.aminodeoxybutirosin (ad-btn), the 5''-amino-5''-deoxy derivative of butirosin (btn), was synthesized to improve on the antibacterial activity of btn by preventing bacterial enzymatic phosphorylation at the 5'' position. ad-btn possesses the spectrum characteristic of btn and gentamicin (gtm) and was active at low levels in vitro against a wide variety of gram-negative species including pseudomonas aeruginosa, indole-positive proteus and serratia marcescens; its action was bactericidal against bo ...197662554
urinary infection in boys.a three-year prospective study.73 boys who presented to their general practitioners over the course of one year with symptoms of urinary-tract infection and were found to have bacteriuria were referred to a three-year prospective study. this included clinical and radiological investigations and monitoring of the preputial flora and midstream-urine culture at monthyl intervals. 22 (30%) of the boys had radiological abnormalities of the urinary tract; 6 had pyelonephritic changes. only 2 required urinary-tract surgery. several ...197662948
[the effect of ear surgery to the immunologic defense system of the middle ear during chronic otitis media (author's transl)].alpha-1-antitrypsin and alpha-2-macroglobuline are very important proteinase inhibitors for the healing process in chronic otitis media, because they can inhibit numerous bacterial and leukocytic proteinases: alpha-2-macroglobuline can block the malignant proteinases of pseudomonas aeruginosa, staphylococcus aureus and proteus vulgaris. in 58 cases in the middle ear secretion was examined and the level of alpha-1-antitrypsin and alpha-2-macroglobulin investigated pre- and postoperatively. by the ...197663098
[effect of levoristatin on intestinal autoflora following oral administration]. 197664919
[experimental infection of domestic animals with r. prowazeki and r. canada].the authors infected lambs with r. prowazeki and r. canada to ascertain their possible role in the natural infection of the animals. the lambs were infected subcutaneously with increasing doses; rickettsiemia was recorded with the aid of tests on guinea pigs and ixodidae and argasidae ticks fed on the lambs. dynamics of antibody formation was ascertained in the infected animals in the agglutination reaction and in the complement fixation test. the antigenic affinity of r. canada and rickettsia o ...197665076
[giant urinary bladder calculi in patients with pseudomonas aeruginosa and proteus vulgaris infections following prostatectomy for prostatic adenoma]. 197768625
purification and properties of beta-lactamase from proteus morganii.the cephalosporin beta-lactamase was purified from a strain of proteus morganii that showed resistance to beta-lactam antibiotics and produced the enzyme constitutively. the purified enzyme preparation gave a single protein band on polyacrylamide gel electrophoresis and consisted of a single polypeptide of molecular weight 38,000 to 40,000 from gel filtration of sephadex g-100 and sodium dodecyl sulfate-acrylamide gel electrophoresis, its isoelectric point being ph 7.2 no cysteine residue was fo ...197770426
a polyvalent human gamma-globulin immune to pseudomonas aeruginosa: passive protection of mice against lethal a means to development of guidelines for therapeutic application to human disease, preparations of human polyvalent gamma-globulin immune to pseudomonas aeruginosa (pg) were studied in acute infections in mice. pg was highly effective in controlling lethal infections induced in mice by the major immunotypes of p. aeruginosa; greater than or equal to 10 microgram of of gamma-globulin per mouse protected against challenge with less than or equal to 10(6) 50% lethal doses of p. aeruginosa. pg wa ...197770492
inhibition of phagocytosis in vitro by obligate anaerobes.a variety of species of obligate anaerobes have been shown to interfere with the phagocytosis and killing of proteus mirabilis and other aerobic bacteria in vitro. although all the obligate anaerobes examined showed this activity, the effect was greatest with strains of bacteroides melaninogenicus and b. fragilis. in contrast, none of the 36 aerobes tested acted in this way. these observations suggest that the presence of obligate anaerobes may be fundamental to the pathogenesis of some types of ...197773952
specific and cross-reactive activation of rabbit peripheral blood lymphocytes by streptococcal vaccines.the ability of primed rabbit blood lymphocytes to respond in vitro to the homologous streptococcal group antigen depends on its presence in culture in the form of vaccine or cell walls thereof. these lymphocytes can also be stimulated in vitro by streptococcal vaccines with chemically related group antigens. the basis for this cross-stimulation apparently resides in shared rhamnose moieties. activation of these lymphocytes was not achieved by vaccines from unrelated bacteria. there is also the s ...197874347
mucocutaneous lymph-node syndrome with positive weil-felix reaction but negative leptospira studies. 197876261
prospective study of the treatment of septic shock.a study of 113 patients with septic shock admitted to an intensive therapy unit (i.t.u.) during a 3-year period showed that a significant reduction in mortality was achieved after the introduction of a treatment programme which included early intermittent positive-pressure ventilation and aggressive surgery in addition to conventional management with fluids, oxygen, and antibiotics. vasoactive drugs played an important but not essential role in therapy.197877955
synthetic disaccharide-protein antigen for production of specific o2 antiserum for immunofluorescence diagnosis of salmonella.antisera from rabbits immunized with the synthetic disaccharide paratose 1 leads to alpha 3 mannose, representive of salmonella o-antigen 2, covalently linked to bovine serum albumin (bsa), were used in indirect immunofluorescence studies for the identification of salmonella serogroup a (o-antigen 1,2,12) bacteria. among 1311 enteric bacteria tested, 497 were salmonella. the anti-paratose 1 leads to alpha 3 mannose-bsa serum identified correctly all the 63 serogroup a strains tested. no positive ...197878659
[dry medium with ampholan for isolation of proteus and providencia]. 197879680
intercontinental nosocomial infections. 197879961
stomach as source of bacteria colonising respiratory tract during artificial ventilation.10 adults had intermittent positive-pressure ventilation for 3--34 days. all 10 had paralytic ileus. microbial overgrowth in the stomach was found in 9 patients (bacterial in 7 and fungal in 2); gram-negative bacteria predominated. the trachea invariably became colonised by bacteria, mainly gram-negative organisms. in 3 instances the gram-negative bacteria were found in the stomach before they appeared in the tracheal aspirate, and in 1 case the pathogen originated in the faeces.197881991
[serotyping of bacteria of the genus proteus isolated from different sources]. 197985743
urinary beta 2 microglobulin in upper and lower urinary-tract infections.beta 2-- microglobulin excretion in 24 h urine collections and beta2- microglobulin clearance were significantly increased in patients with upper-urinary-tract infections, but beta 2- microglobulin clearance and excretion were normal in patients with cystitis. beta 2-microglobulin estimation may be used to distinguish between upper and lower urinary-tract infections, except when pre-existing tubular damage is present. voided urine must have a ph above 6 . 0, since beta 2- microglobulin is rapidl ...197986044
serological investigations on ribitol-containing lipopolysaccharides from proteus mirabilis.lipopolysaccharides containing or noncontaining ribitol derived from several proteus mirabilis strains were studied using passive hemagglutination, hemagglutination-inhibition and semi-quantitative precipitin tests. the results indicate that ribitol plays a role in the serological specificity of the respective lipopolysaccharides.197886334
the role of lysine in the serological specificity of some proteus mirabilis lipopolysaccharides. 197886335
[use of simmons' medium for isolating pseudomonas aeruginosa from associations with proteus]. 197986654
[histamine liberation in the fish meat infected with proteus morgani]. 197992805
an in vitro study on the effect of benzoyl peroxide 20%, gentamicin and phenoxyethanol on staphylococcus aureus, pseudomonas aeruginosa and proteus species. 197994224
identification of bacteroides fragilis by indirect immunofluorescence.rabbit antiserum against live or heat-killed bacteroides fragilis nctc 9343 bacteria was titrated against hot phenol water-extracted polysaccharide antigens from five different species of the 'b. fragilis group' of bacteria using an enzyme immunoassay and shown to be specific for the b. fragilis nctc 9343 polysaccharide. when the antiserum was used in indirect immunofluorescence, 97.1% of 244 b. fragilis strains were correctly identified. only 8 of the other 312 bacteroides strains were stained ...197994651
mezlocillin: a new acyl ureidopenicillin. antimicrobial activity and combination effects with four aminoglycoside antibiotics.mezlocillin (baypen), carbenicillin and mezlocillin combined with gentamicin, sisomicin, tobramycin and amikacin, respectively, were tested in vitro against 325 fresh clinical isolates of pathogenic gram-negative bacteria using the tube dilution procedure. the new acyl ureidopenicillin has a greater antimicrobial activity than carbenicillin against nearly all species tested. the comparison of the effectiveness of the mezlocillin-aminoglycoside combinations demonstrates the superiority of mezloci ...197895925
activity of azlocillin and mezlocillin against gram-negative organisms: comparison with other penicillins.the activities of azlocillin and mezlocillin were compared with those of carbenicillin, ticarcillin, and pirbenicillin against a wide range of gram-negative organisms. the two new drugs were considerably more active than carbenicillin against klebsiella species and escherichia coli. carbenicillin was twice as active against proteus mirabilis as mezlocillin and four times as active as azlocillin. against pseudomonas aeruginosa, azlocillin was eight times as active as carbenicillin. azlocillin and ...197896726
beta-lactamases: determination of their isoelectric points.important discrepancies in isoelectric points (pi) of beta-lactamases were observed depending on the experimental procedure used for their determination: isoelectric focusing (ief) in sucrose density gradients or analytical ief in thin-layer polyacrylamide gels (pa). the variations, negligable in the case of tem-like beta-lactamases, appeared to be important in the case of cephalosporinases and are related to an artifact which appears in pa-ief. this has been clearly shown with beta-lactamase pr ...197896731
sk&f 75073, new parenteral broad-spectrum cephalosporin with high and prolonged serum 75073, a new parenteral cephalosporin, was found to have broad in vitro and in vivo antibacterial activity including isolates usually resistant to cephalothin and cefazolin. this activity included indole-positive proteus and enterobacter species and some serratia isolates. proteus mirabilis strains were particularly susceptible, as were haemophilus influenzae and neisseria species. the activity of sk&f 75073 against gram-positive bacteria was poorer than that of the control cephalosporins. ...197896734
vesicoureteral reflux in the primate: iii. effect of urinary tract infection on maturation of the ureterovesical junction.recurrent bladder infections in the monkey appeared to cause a delay in maturation of the ureterovesical junction. this was not significant since it did not ultimately prevent maturation. bacteriuria was prolonged when reflux was present.197897618
gentamicin-resistant gram-negative bacilli in hospital patients. part i. preliminary epidemiological assessment.gentamicin-resistant gram-negative bacilli (grnb) have been isolated from specimens received from 23 hospitals in and around johannesburg. most isolates are fermentative in nature. a pilot survey among inpatients at the johannesburg hospital revealed an intestinal carriage prevalence of 14,3%. a prospective study of intestinal acquisition showed that grnb are acquired in hospital, and that colonization is associated with prior antibacterial therapy. analysis of clinical specimens received from t ...197897791
chymotrypsinlike activity of some intestinal bacteria.some tests of exocrine pancreatic function are based on the estimation of intestinal chymotryptic activity by using specific substrates such as n-benzoyl-l-tyrosyl-paba (bt-p). in this study the action of a number of bacteria isolated from human or monkey intestines on bt-p was investigated. the monkeys studied had an intestinal flora closely resembling that of man. except for bacteroides, proteus vulgaris no. 73, proteus morgani no. 202, and pseudomonas aeruginosa no. 76, significant splitting ...197898039
[increase in tetracycline activity by using surface-active substances].the antimicrobial effect of cationic and anionic surface-active substances, i.e. catamine ab and sulphonol np-3 respectively was studied in vitro with respect to gramnegative bacteria. in non-bactericidal concentrations catamine ab significantly increased the efficacy of tetracyclines, while the anionic compound had no such effect. the increase in the tetracycline activity was due to the antibiotic increased absorption (14c-oxytetracycline as an example) on the treatment of gramnegative bacteria ...197898103
differences in the immune response of the antibodies to proteus-antigen in patients with tumorous and non-tumorous diseases. 197798407
in vitro susceptibility of gentamicin and/or tobramycin resistant gram-negative bacilli to seven aminoglycosides.the in vitro activity of gentamicin, tobramycin, sisomicin, netilmicin, amikacin, kanamycin and streptomycin was tested simultaneously by the agar dilution method against 584 clinical isolates of gram-negative bacilli that were resistant to gentamicin and/or tobramycin. about half of the gentamicin-resistant pseudomonas were susceptible to tobramycin but cross-resistance was virtually complete between gentamicin and tobramycin for enterobacteriaceae. sisomicin was much more active than gentamici ...197898451
aperistaltic ureter in upper urinary tract infection--cause or effect? 197899855
[the present situation of antibacterial resistance (author's transl)].the various types of bacterial resistance (natural species resistance, chromosomal and plasmidic resistance) and their mechanisms are described. thereafter, a survey on the resistance is given using investigations from different sources. the distribution of resistant strains dependent on the geographical location and the situation of the patients (ambulatory--hospitalized) is described, and the development of resistant strains in dependance of time is analyzed. finally, the phenomena of resistan ...1978100410
[testing the disinfectant effect of calcium peroxide as a root canal filling material].the authors have been using with success calcium peroxide as a root-canal filling material for many years. its bactericidal and bacteriostatic effects are tested. germ carrier tests illustrate the suitability of its pasty preparation for root-canal disinfection.1978100905
demonstration of membrane-associated and oriented microfilaments in amoeba proteus by means of a schiff base/glutaraldehyde fixative.after fixation with a reaction product of glutaraldehyde and spermidine phosphate amoeba proteus cells show a network of cortical microfilaments and oriented bundles of thick and thin filaments. the cortical filament network appears to be membrane-attached and extends beneath the whole cytoplasmic membrane surface. in the uroid region and in retracting pseudopods the cortical layer is thicker than in advancing cell regions. the filament bundles are located predominantly in the ectoplasmic tube w ...1978101401
new antibiotics, enaminomycins a, b and c. ii. physico-chemical and biological properties.physico-chemical characterization of enaminomycins revealed that these antibiotics are new members of the epoxy quinone family. from elementary analysis and mass spectroscopic measurements the molecular formulae of enaminomycins a, b and c appear to be c7h5no5, c10h11n06 and c7h7no5, respectively. they are very unique in their chemical properties, possessing various functions, such as epoxy, primary amine and carboxylic acid, in their small structural units. enaminomycin a, the most potent compo ...1978101500
rifampicin plus nalidixic acid: a rational combination for the treatment of urinary infection. 1978101503
[clinical evaluation of t-1220 (piperacillin) in otorhinolaryngological field (author's transl)]. 1977101608
[microbiological characteristics of intestinal dysbacteriosis in acute leukemia]. 1978101983
[effect of sodium fluoride on samples of oral flora. clinical application]. 1977102105
[simple qualitative methods of detecting beta-lactamase-producing strains of microorganisms].modifications of two microbiological qualitative methods for detection of beta-lactamase-producing microbial strains are described. the methods are based on the principle of goths. one of the methods named "contact" significantly differs from the prototype and is more simple, convenient, easily reproducible and does not require the use of special equipment and special training of the staff.1978102243
comparison of the in vitro activity of bay k 4999 and piperacillin, two new antipseudomonal broad-spectrum penicillins, with other beta-lactam drugs.bay k 4999 and piperacillin, two new substituted ampicillins, were compared with other beta-lactam antibiotics, including carbenicillin, azlocillin, mezlocillin, benzylpenicillin, ampicillin, and cefoxitin, against a wide range of gram-positive and -negative organisms. bay k 4999 and piperacillin were extremely active against pseudomonas aeruginosa (50% inhibited by 2 mug/ml), being about 16-fold more active than carbenicillin. bay k 4999 was the most active drug against escherichia coli (50% in ...1978102245
in vitro activity of hr 756, a new cephalosporin compound.the in vitro activity of hr 756, a new cephalosporin, has been determined against recent clinical isolates and compared with that of other beta-lactam antibiotics. the geometric means of the minimum inhibitory concentrations (mic) for different isolates of escherichia coli (100 isolates), klebsiella pneumoniae (84), pseudomonas aeruginosa (121), proteus mirabilis (52), indole-positive proteus species (9), salmonella species (19), staphylococcus aureus penicillin-sensitive (29) and penicillin-res ...1978102631
[experiences with the uripret-system in pediatric practice (author's transl)].the present study reports on the application of the uripret-system for identification and susceptibility testing of microbial agents causing urinary tract infections carried out in a pediatric outpatient clinic. the findings were compared with those determined with the conventional methods in an institute of medical microbiology. for the detected mono- and mixed-cultures, in 85% of the cases a concurrent result of both methods was found. only in one case a different microbial agent genus was det ...1979102911
[detection of antibodies to rickketsia prowazekii by using the antigen neutralization test].the authors studied a possibility of using the antigen neutralization test with dry immunoglobulin typhus erythrocytic diagnostic agent for the purpose of detection of rickettsia prowazeki antibodies. blood sera of 315 healthy persons, 24 patients with sporadic typhus, and 18 laboratory animals immunized with r. sibirica and r. burneti, as well as with proteus ox19 were examined. the results obtained pointed to the high specificity and sensitivity of the given serological test. a possibility of ...1978103341
[susceptibility testing with the autobac system (author's transl)].the autobac i provides an automated method for the rapid measurement of antimicrobial susceptibility of fast growing pathogenic microorganisms. to check instrument accuracy, 477 cultures were tested by the bauer-kirby method for comparison. according to the din limits, the results were comparable in 81.8%, whereas within the nccls limits the agreement was 86.5%. the discrepancy was found to be due to incorrect disc mass and different limits of inhibitory zone diameters. another reason for disagr ...1978103806
[efficacy, tolerance, and pharmacokinetics of sisomicin in urinary tract infections (author's transl)].since 1973 30 patients with urinary tract infections (uti) or pyelonephritis have been treated with sisomicin, a new aminoglycoside, in a daily dose of 2 mg/kg for a period of seven to nine days. from a clinical point of view the result of treatment was good. complete resolution was achieved in 17 patients, improvement in nine, and there was no effect in four patients. thirty-five causative organisms (escherichia coli = 23, proteus sp. = 7, klebsiella sp. = 3, pseudomonas aeruginosa = 1, citroba ...1978103844
synergism between chlorhexidine and sulphadiazine. 1978103874
homology of the gene coding for outer membrane lipoprotein within various gram-negative bacteria.the mrna for a major outer membrane lipoprotein from escherichia coli was found to hybridize specifically with one of the ecori and one of the hindiii restriction endonuclease-generated fragments of total dna from nine bacteria in the family enterobacteriaceae: e. coli, shigella dysenteriae, salmonella typhimurium, citrobacter freundii, klebsiella aerogenes, enterobacter aerogenes, edwardsiella tarda, serratia marcescens, and erwinia amylovora. however, among the enterobacteriaceae, dna from two ...1979104972
[antibacterial activity of fosfomycin in chronic kidney infections].authors have carried out a retrospective study in vitro on the bacteria isolated from renal parenchyma and stones in patients with cpn associated to kidney stones. results show a different inhibitory action of the some antibiotics to proteus, e. coli and p. aeruginosa. fosfomycin inhibits the growth of bacteria in a wide range of concentration (50-1000 microgram/ml). a prospective study in vivo shows an excellent therapeutic action of fosfomycin in recurrent urinary infections, and a very good o ...1978105327
[our experience in the use of fosfomycin in human therapy]. 1978105328
defective cellular immunity to gram-negative bacteria in cystic fibrosis vitro lymphocyte responses to pseudomonas aeruginosa have been found to be impaired in cystic fibrosis patients with advanced clinical disease. the responses to klebsiella pneumoniae, serratia marcescens, and proteus mirabilis were studied in a similar group of cystic fibrosis patients and normal individuals. cystic fibrosis patients found to be unresponsive to pseudomonas were also unresponsive to klebsiella, serratia, and proteus. responsiveness to staphylococcus aureus was not impaired in ...1979106011
diagnosis of intra-amniotic infection. 1977106471
interpretive criteria for cefamandole and cephalothin disk diffusion susceptibility tests.a multi-center study of 1,838 clinical isolates established the accuracy of diffusion susceptibility tests with 30-mug cephalothin disks and 30-mug cefamandole disks. the same interpretive zone standards can be applied to tests with either disk but the two drugs cannot be tested interchangeably.1979106770
[intensification of antibacterial and antiviral nonsusceptibility and of the immune response with an officinal rna preparation].sodium nucleinate increased essentially the insusceptibility of mice to pathogenic escherichia, strain o26, pr. vulgaris, ps. aeruginosa, ser. marcescens, and produced a total stimulating effect on the nonspecific bacterial resistance; analogous stimulating activity was found in the homologous low polymeric rna from the liver. sodium nucleinate intensified the insusceptibility of the animals to the tick-born encephalitis and encephalomyelitis viruses, and increased the antibody-forming cells cou ...1979106911
effect of active and passive antibacterial immunization on skin allograft survival in rabbits.the effect of active and passive antibacterial immunization on transplantation immunity was investigated in rabbits. immunization with dead bacterial vaccines prepared from e. coli, proteus mirabilis and pseudmonas aeruginosa had no effect on skin allograft survival, whereas immunization with vaccines prepared from streptococcal and staphylococcal strains shortened allograft survival. similar results were obtained with specific antisera against individual microbial species. skin allografts survi ...1979107050
discrepancies in weil-felix and microimmunofluorescence test results for rocky mountain spotted fever.only 4.2% of 284 single specimens and 17.6% of 51 pairs of sera reactive in weil-felix agglutination tests for rocky mountain spotted fever were confirmed by a specific rickettsia rickettsii microimmunofluorescence test.1979107194
[antibacterial activity of gentamicin, tobramycin, amikacin, and sisomicin in vitro (author's transl)]. 1978107386
antibiotic resistance in various medical services.the analysis of differences in occurrence of antibiotic-resistant strains belonging to ten species of "problem" bacteria was performed by means of a computer program in more than 150,000 bacterial strains isolated in slovakia in 1977. in all respects, strains isolated in general medical practice were considerably more sensitive to classical as well as to newer antibiotics. marked differences in resistance within individual medical services could be a reflection of both quantitative and qualitati ...1979108222
minimal antibiotic concentrations of aminoglycosides and beta-lactam antibiotics for some gram-negative bacilli and gram-positive cocci.the minimal antibiotic concentration (mac) is the lowest concentration of an antibacterial agent that produces a decrease of 1 log in the number of organisms/ml as compared with a control culture in drug-free medium. various gram-negative bacilli and gram-positive cocci were grown in the presence of amikacin, gentamicin, tobramycin, ampicillin, amoxicillin, oxacillin, carbenicillin, ticarcillin, and cefamandole at concentrations varying from eight times the minimal inhibitory concentration (mic) ...1979108345
distribution of the hematozoa of neotropical birds.the literature pertaining to the prevalence of avian hematozoa in the neotropics, together with unpublished records from the files of the international reference centre for avian haematozoa, has been examined with respect to the distribution of parasite genera by host family and region. the blood parasites of 35555 birds of 955 species (80 families) occurring in the neotropics formed the basis for the comparisons. only 3743 (10.5%) individuals harbored one or more species of hematozoa. haemoprot ...1978108771
epidemic occurrence of neonatal necrotizing case-control studies of three epidemics of neonatal necrotizing enterocolitis (nec) in three different high-risk nurseries in three states, no particular risk factor was associated with affected infants or their mothers. epidemic cases had higher birth weights and apgar scores and fewer perinatal difficulties than those previously reported for sporadic cases. seven infants fed primarily breast milk were not protected against disease. early antibiotic therapy was associated with a significantl ...1979108997
comparison of serum and prostatic levels of tobramycin.tobramycin sulfate, an aminoglycoside antibiotic, has been shown to be effective in the treatment of complicated urinary tract infections. because of this, a study was undertaken to determine the penetrance of tobramycin into the prostate gland. it was found that the drug is concentrated at inhibitory levels in the prostate gland after the routinely recommended administration and should be useful in the treatment of bacterial prostatic infection.1979109981
aminopeptidase i activities in several microorganisms.aminopeptidase i activity which was found to be localized in the same subcellular fraction and to be similarly heat stable was partially purified by a common procedure from escherichia coli b, escherichia coli k12, enterobacter aerogenes, salmonella typhimurium, serratia marcescens pseudomonas aeruginosa, and proteus vulgaris. the enzyme preparations were shown to contain a single animopeptidase active toward both leucylleucine and methionylalanylserine by mixed-substrate initial-velocity kineti ...1978110425
[antibacterial in-vitro activity of pipemidic acid and nalidixic acid (author's transl)].the in-vitro activity of nalidixic acid and pipemidic acid was investigated in a combined study in 450 freshly isolated bacterial strains using the agar dilution test. gram-positive cocci were resistant to both substances except for a few pipemidic acid sensitive staphylococci. both substances had good antibacterial activity in the gram-negative spectrum. however, the mic values of pipemidic acid were generally clearly lower than those of nalidixic acid. only pipemidic acid showed activity again ...1979110574
[adjuvant effect of tuberculin on sensitivity to gram negative bacteria]. 1979111205
in vitro activity of piperacillin compared with that of carbenicillin, ticarcillin, ampicillin, cephalothin, and cefamandole against pseudomonas aeruginosa and enterobacteriaceae.piperacillin (t-1220), a semisynthetic derivative of aminobenzylpenicillin, was more active than either carbenicillin or ticarcillin against pseudomonas aeruginosa; over 60% of isolates were inhibited at a concentration of 6.3 mug/ml. piperacillin was bactericidal for 84% of pseudomonas strains at 100 mug/ml, carbenicillin killed 60%, and ticarcillin killed 68% at that concentration. piperacillin was also more active than the other penicillins against isolates of escherichia coli, enterobacter, ...1979111609
comparative in vitro activity of azlocillin, ampicillin, mezlocillin, piperacillin, and ticarcillin, alone and in combination with an aminoglycoside.the in vitro activities of the newer semisynthetic penicillins azlocillin, mezlocillin, and piperacillin were compared with those of ampicillin and ticarcillin by using 290 clinical laboratory isolates. piperacillin and mezlocillin were the most active against escherichia coli, proteus mirabilis, klebsiella spp., and enterobacter spp. when pseudomonas aeruginosa was tested, piperacillin and azlocillin were more active than either mezlocillin or ticarcillin. streptococcus pneumoniae and haemophil ...1979111616
[resistance to tetracycline and doxycycline in bavaria (author's transl)].the in vitro sensitivity of tetracycline and doxycycline is compared. streptococcus and staphylococcus are more sensitive to doxycycline whereas pseudomonas and proteus spec. are more sensitive to tetracycline.1979112366
antibacterial activity of a new parenteral cephalosporin--hr 756: comparison with cefamandole and 756, a new parenteral cephalosporin that is beta-lactamase resistant, was tested against 271 bacterial isolates. both agar and broth dilution testing were employed, using two media and two inoculum sizes of bacteria. antibacterial activity of the drug was compared to that of cefamandole (cfm) and ceforanide (cfn). in agar, hr 756 was more active than cfm and cfn against all bacteria tested except isolates of staphylococcus aureus, which were better inhibited by cfm. hr 756 exhibited some anti ...1979112919
in vitro comparison of rosamicin and erythromycin against urinary tract pathogens.the in vitro activity of rosamicin and erythromycin was compared at various ph values against 311 strains of bacteria representing common urinary tract pathogens. alkalinization of the media consistently and significantly increased the antibacterial activity of rosamicin against all of the organisms tested. this was also true for erythromycin except when tested against strains of proteus. at ph 8, rosamicin was two- to sixfold more active than erythromycin against enterobacteriaceae. the activit ...1979112920
in vitro efficacy of bay k 4999, a new ureido-penicillin, in combination with aminoglycosides against pseudomonas aeruginosa, escherichia coli, klebsiella pneumoniae and proteus strains.the in vitro effects of bay k 4999 in combination with gentamicin, tobramycin, amikacin sisomicin and netilmicin in bacteriostatic (mic) and bactericidal (mbc) concentrations were compared using the checkerboard dilution technique against 20 different strains of pseudomonas aeruginosa, escherichia coli, klebsiella pneumoniae and indole-positive-negative proteus species. on average 63% of bay k 4999-aminoglycoside (ag) combinations inhibited pseudomonas, proteus and klebsiella strains additively ...1979113178
a comparison of the in vitro activity of tobramycin and gentamicin against 6,042 clinical isolates.6,042 strains of staphylococcus aureus, streptococcus faecalis, proteus mirabilis, escherichia coli, klebsiella sp. and pseudomonas sp. were tested against tobramycin and gentamicin. among all species studies, except pseudomonas sp, gentamicin turned out to be slightly superior to tobramycin.1979113179
[characteristics of current antibiotic therapy]. 1979113612
effect of concentration on bactericidal activity of cefotaxime. 1979114510
[effect of combination of hetacillin, cephapirin and amikacin (author's transl)].with the investigations of the effect of combination of hetacillin, cephapirin and amikacin, following experimental results were obtained; 1. effect of combination of amikacin, cephapirin and hetacillin was differed depending upon the genus and species of bacteria. however, in general, in the cases showing effective results there was a relation in the concentration of these antibiotics. with strains of escherichia coli amikacin and cephapirin was cooperative, but not with other combinations and ...1979114683
[the treatment of bacterial infections in surgery with sisomicin]. 1979114805
a new method of preparation of pyocyanin and demonstration of an unusual bacterial sensitivity. 1979115327
optimal dosage regimen for penicillins: bolus or continuous infusion? 1979115829
granulocyte adherence assay in acute infection as a reflection of the host resistance.the in vitro granulocyte adherence assay was used in six healthy individuals and 14 patients who had acute gram-negative infection to determine whether or not the assay is altered with acute infection and whether or not it adequately reflects the host resistance. the granulocyte adherence values for all patients were significantly lower than those for healthy individuals. in eight patients who recovered, the initial mean value did not differ from that of six patients who died, 7.2 +/- 5.9 and 7. ...1979116380
competition of beta-lactam antibiotics for the penicillin-binding proteins of pseudomonas aeruginosa, enterobacter cloacae, klebsiella aerogenes, proteus rettgeri, and escherichia coli: comparison with antibacterial activity and effects upon bacterial morphology.the competition of a number of beta-lactam morphogenic probes for the penicillin-binding proteins (pbps) of pseudomonas aeruginosa, enterobacter cloacae, klebsiella aerogenes, proteus rettgeri, and escherichia coli has been studied. the results indicate that the various gram-negative bacteria have similar, but not identical, pbp patterns and that the individual proteins probably perform similar morphogenic functions as in e. coli k-12. comparison of the 50% binding concentrations of the compound ...1979116592
3-[(1,2,3-thiadiazol-5-ylthio)methyl]cephalosporins.the syntheses of ten 3-](1,2,3-thiadiazol-5-ylthio)methyl]cephalosporins, made by displacement of the 3'-acetoxy group by the novel thiol derivatives, potassium 1,2,3-thiadiazole-5-thiolate and dipotassium 1,2,3-thiadiazole-4-carboxylate-5-thiolate, are described. several of the compounds showed good in vitro antibacterial activity against both gram-positive and gram-negative organisms. the subcutaneous in vivo activities against staphylococcus aureus were generally less than that of cafazolin. ...1979117106
oropharyngeal microflora in aboriginal and non-aboriginal australian children. an indicator of environmental contamination.faecal microorganisms, not normally resident in the oropharynx, were isolated much more often from aboriginal than non-aboriginal australian children. this is almost certainly due to differences in standards of hygiene and living in these two groups, and is an important factor in contributing to the common and serious problem of gastrointestinal infections in young aborigines. in the non-aboriginal group, the isolations of faecal organisms were much more common from infants and from children und ...1979117289
[epidemiology of hospital-acquired urinary tract infections (author's transl)].among hospital-acquired infections, urinary tract infections are the widest spread. the most common pathogenic agents are e. coli, enterococci and proteus mirabilis. indwelling bladder catheters account for about 70% of infections. suprapubic urine drainage can reduce the incidence of urinary tract infections by approximatively 50%.1979117318
[hospital acquired urinary tract infection (author's transl)].to explain hospital acquired urinary tract infections in a urological clinic, 3691 case histories were evaluated. about 15% of iatrogenic infections were found, among them 7% bacteremias and 0.9% of cases with urosepsis. autoinfection and intermittent infections should be differentiated. the iatrogenic infection can be prevented by avoiding certain diagnostic and operative interventions, observation of asepsis and exact indication, the autoinfection and intermittend infection by shortening the p ...1979117320
the automicrobic system for evaluation of the automicrobic system (ams) for urines (vitek systems, inc.) was carried out under the auspices of the product evaluation committee of the college of american pathologists from the period june 1977 through october 1978. data generated during this evaluation indicated that, when comparing the ams methodology to our clinical microbiology laboratory methodology, a 37% time saving could be realized by utilizing the ams. quantitation with the ams showed a 99% correlation with the c ...1979118176
[etiotropic treatment of patients with calculous pyelonephritis]. 1979118533
in vitro and in vivo laboratory studies on three hydroxyiminophenylacetyl cephalosporins with particular reference to sk&f 80303, an unusually long-acting cephalosporin.three cephalosporins with 7-(2-hydroxyiminophenylacetamido) side chains (sk&f 79433, 80000 and 80303), differing in their 3-substituents, exhibited similar broad-spectrum antibacterial activity in vitro against strains of staphylococcus aureus, streptococcus faecalis and various gram-negative bacilli. all three were active in vivo (s.c., mouse) against s. aureus, escherichia coli or klebsiella pneumoniae, but they differed significantly in serum pharmacokinetic profiles. sk&f 80303 produced high ...1979118958
magnetic susceptibility of magnetic susceptibility of 13 species and varieties of bacteria was investigated using the relative method of guy. it has been established that the index of magnetic susceptibility is a constant characteristic of bacteria. total magnetic susceptibility ranged from --0.3295.10(-6) in escherichia p678 to --0.4965.10(-6) in proteus. it has also been established that magnetic susceptibility changes during long-term passages of bacteria in fluctuating +/- 0.1 oe) magnetic field. this is suggest ...1979118995
bacteriology of rattlesnake venom and implications for therapy.although the incidence of infection secondary to the bites of venomous snakes remains unknown, the routine use of prophylactic antimicrobial therapy is advocated. in this study, the venom from 15 rattlesnakes was cultured, and 58 aerobic and 28 anaerobic strains of bacteria were isolated. the most common species isolated were pseudomonas aeruginosa, proteus species, coagulase-negative staphylocci, and clostridium species. bacteroides fragilis was also recovered. when the fang sheaths of four add ...1979119002
[capacity of oligonitrophilic bacteria to utilize extracellular polysaccharides as a dehydrogenase substrate]. 1979119138
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