PMID(sorted ascending)
most frequent causes of urinary tract infections in determine the most frequent causes of urinary tract infection (uti) amongst children according to gender and age.201020514772
development of an oregano-based ointment with anti-microbial activity including activity against methicillin-resistant staphlococcus aureus.increasing antibiotic resistance has prompted a search for new compounds with anti-microbial activity. in the authors' previous study, oregano extract was identified as one of the most potent anti-microbial compounds. the disk diffusion method was employed to assess the degree of inhibition against various microorganisms, and the bacteriostatic or bactericidal mechanism of action. disk diffusion studies showed that oregano was found to be bacteriostatic for staphylococcus aureus (s. aureus) and ...201020514796
effect of uropathogens on in vitro encrustation of polyurethane double j ureteral stents.polyurethane stents are used when there is an obstruction to the flow of urine. a majority of the patients with such stents are at the risk of urinary tract infection and salt encrustation. the present study is aimed at analyzing the in vitro encrustation of calcium oxalate and other salts in the presence of common uropathogens (e. coli and p. mirabilis) on films made from tecoflex(®), a commercial grade polyurethane. in the absence of uropathogens, sodium ions and ammonia favor calcium adsorpti ...201120517602
[a case of large vesicourethral stone resulting from long-term retention of a foley catheter].we report a case of a large vesicourethral stone resulting from a long-term indwelling urethral catheter. a 66-year-old man visited our hospital emergency room on october 24, 2006 with a chief complaint of difficult urination. although a urethral catheter was inserted temporarily based on the diagnosis of the doctor on duty, the patient did not return to our hospital for follow-up examination. on july 10, 2008, he was wheeled into our hospital with symptoms of general fatigue, urinary retention ...201020519926
antimicrobial susceptibility of gram-negative nonurinary bacteria to fosfomycin and other antimicrobials.fosfomycin is an antimicrobial commonly used in uncomplicated urinary tract infections. the microbiological effectiveness of fosfomycin against nonurinary gram-negative isolates has not been widely investigated. the aim of this study was to evaluate the in vitro activity of fosfomycin against gram-negative nonurinary isolates in a region of greece where considerable antimicrobial resistance has been detected.201020521939
synthesis, nematicidal and antimicrobial activity of 3-(5-3-methyl-5-[(3-methyl-7-5-[2-(aryl)-4-oxo-1,3-thiazolan-3-yl]-1,3,4-thiadiazol-2-ylbenzo[b]furan-5-yl)methyl]benzo[b]furan-7-yl-1,3,4-thiadiazol-2-yl)-2-(aryl)-1,3-thiazolan-4-one.a new series of 3-(5-3-methyl-5-[(3-methyl-7-5-[2-(aryl)-4-oxo-1,3-thiazolan-3-yl]-1,3,4-thiadiazol-2-ylbenzo[b]furan-5-yl)methyl]benzo[b]furan-7-yl-1,3,4-thiadiazol-2-yl)-2-(aryl)-1,3-thiazolan-4-one 5a-j has been synthesized by the reaction of n2-[(e)-1-(4-methylphenyl)methylidene]-5-(3-methyl-5-[3-methyl-7-(5-[(e)-1-(4-methylphenyl)methylidene]amino-1,3,4-thiadiazol-2-yl)benzo[b]furan-5-yl]methylbenzo[b]furan-7-yl)-1,3,4-thiadiazol-2-amine 4a-j with thioglycolic acid. chemical structures of a ...201020522990
antimicrobial susceptibility of pediatric uropathogens in thrace, greece.the aim of this study was to investigate the bacterial pathogens involved in pediatric urinary tract infections (utis) in a tertiary general hospital located in the thrace province of northern greece over a 69-month period (1/2003 to 9/2008), and their antibiotic susceptibility patterns. a total of 622 episodes of utis in 508 children were identified. median age of all children was 16 months (range 1 month to 14 years). boys were significantly younger than girls (9 months vs. 24 months). escheri ...201120524067
[etiologic factors in urinary tract infection investigated in ambulatory setting. community-acquired urinary tract infection: etiologic aspects and antibiotic resistance].urine bacteriological examination is one of the most frequently asked for examinations, in ambulatory as well as in hospitals, regarding specialty prophyle. the present study comprises a group of 3971 pacients that were sent to the laboratory for uroculture and showed a percentage of only 21.85% significant urocultures--the etiological groups most frequently isolated being gram-negative bacilli--96.05%, respectively escherichia sp. 76.95%, klebsiella sp. 14.68%, proteus sp. 4.66%. out of the gra ...200920524391
theoretical study of the catalytic mechanism of dna-(n4-cytosine)-methyltransferase from the bacterium proteus this paper the reaction mechanism for methylation of cytosine at the exocyclic n4 position catalyzed by m.pvuii has been explored by means of hybrid quantum mechanics/molecular mechanics (qm/mm) methods. a reaction model was prepared by placing a single cytosine base in the active site of the enzyme. in this model the exocyclic amino group of the base establishes hydrogen bond interactions with the hydroxyl oxygen atom of ser53 and the carbonyl oxygen atom of pro54. the reaction mechanism inv ...201020524651
identification and antimicrobial susceptibility patterns of bacteria causing otitis externa in dogs.bacterial agents are considered important pathogens causing external otitis in dogs. it is essential to carry out bacterial culture and antimicrobial susceptibility test in the case of otitis externa, particularly for chronic or recurring cases. sterile swab samples were obtained from terminal part of vertical ear canals of 74 dogs with otitis externa for cytology, bacterial culture and antimicrobial susceptibility test. cytologic smears were stained using gram and giemsa staining methods. aerob ...201020526674
[clinical assessment of novel chromid esbl agar plates for detection of esbl producers in the family enterobacteriaceae].extended-spectrum beta-lactamase (esbl)-producers in the family enterobacteriaceae are recognized worldwide as nosocomial pathogens, however it is difficult to screen them in the routine laboratory processing. chromid esbl agar newly developed for screening esbl-producing enterobacteriaceae was released in japan in april, 2007. we evaluated the clinical assessment of chromid esbl agar in routine microbiology laboratory. the 47 strains investigated were clinical isolates belonging to the family e ...200920528091
the use of lytic bacteriophages in the prevention and eradication of biofilms of proteus mirabilis and escherichia coli.antibiotics have been the cornerstone of the clinical management of bacterial infections since their discovery in the early part of the last century. eight decades later, their widespread, often indiscriminate use, has resulted in an overall reduction in their effectiveness, with reports of multidrug-resistant bacteria now commonplace. increasing reliance on indwelling medical devices, which are inherently susceptible to biofilm-mediated infections, has contributed to unacceptably high rates of ...201020528927
the group of epidermal nevus syndromes part i. well defined phenotypes.the epidermal nevus syndromes represent a group of distinct disorders that can be distinguished by the type of associated epidermal nevus and by the criterion of presence or absence of heritability. well defined syndromes characterized by organoid epidermal nevi include schimmelpenning syndrome, phacomatosis pigmentokeratotica, nevus comedonicus syndrome, angora hair nevus syndrome, and becker nevus syndrome. the molecular basis of these disorders has so far not been identified. by contrast, the ...201020542174
the group of epidermal nevus syndromes part ii. less well defined addition to the well established epidermal nevus syndromes, such as schimmelpenning, becker, proteus, child, or nevus comedonicus syndromes, the group of less well defined phenotypes associated with epidermal nevi presently includes nevus trichilemmocysticus syndrome, didymosis aplasticosebacea, scalp syndrome (sebaceous nevus, central nervous system malformations, aplasia cutis congenita, limbal dermoid,and pigmented nevus), gobello syndrome, bäfverstedt syndrome, nevada syndrome (nevus epid ...201020542175
comparative in vitro activity of cefditoren and other antimicrobials against enterobacteriaceae causing community-acquired uncomplicated urinary tract infections in women: a spanish nationwide multicenter study.cefditoren is a third-generation orally administered cephalosporin with a broad spectrum of activity against gram-positive and gram-negative bacterial species. after an oral 400-mg single dose, the mean concentrations in urine are 186.5 mg/l at 2 to 4 h and 12.7 mg/l at 8 to 12 h, and it is a potential drug to be used in the treatment of urinary tract infection (uti). we performed a multicenter nationwide study in spain in order to determine the in vitro activity of cefditoren and other comparat ...201020542206
[detection of bla(ctx-m) beta-lactamase genes in extended-spectrum beta-lactamase producing gram-negative bacteria].widespread production of ctx-m type extended-spectrum beta-lactamases (esbl) in enterobacteriaceae strains which are resistant to extended-spectrum cephalosporins is the most remarkable example for rapid and global spread of plasmid mediated antimicrobial resistance in bacteria. consecutive 200 esbl producing enterobacteriaceae strains out of 1640 isolates that were obtained from clinical samples (167 urine, 11 wound, 7 bronchoalveolar lavage, 3 peritoneal fluid, 2 cerebrospinal fluid, 2 biopsy, ...201020549952
emergence of proteus mirabilis isolates producing tem-52 extended-spectrum beta-lactamases in increased frequency of extended-spectrum beta-lactamase (esbl)-positive proteus mirabilis isolates was observed recently in the clinical hospital center split in croatia. the aim of this study was the molecular characterization of esbls in p. mirabilis isolates from this hospital.201020551637
a genome-wide analysis of loss of heterozygosity and chromosomal copy number variation in proteus syndrome using high-density snp microarrays.excessive cell proliferation and genetic changes such as loss of an allele (loss of heterozygosity (loh)) or amplifications or deletions of parts of chromosomes (copy number variations (cnv)) are common findings in cancers. it is unknown whether these changes are also present in patients with overgrowth syndromes, although the presence of small-scale cnvs (such as duplication of 11p15 in beckwith-wiedemann syndrome), excessive cell proliferation and an increased frequency of tumors have all been ...201020555334
determinants of beta-lactam resistance in meningitis-causing enterobacteriaceae in brazil.this study analyzed resistance determinants in extended-spectrum beta-lactamase (esbl)-producing enterobacteria and the epidemiology of 11 escherichia coli isolates obtained from meningitis patients in a region of brazil from 2000 to 2005. esbl-encoding genes and their genetic environment were investigated by pcr and sequencing. the gene blactx-m-2 was identified in 3 different enterobacteria (e. coli, serratia marcescens, and proteus mirabilis) downstream of the insertion sequence iscr1 (locali ...201020555402
synthesis, antibacterial activity evaluation and qsar studies of novel dispiropyrrolidines.a series of novel dispiropyrrolidines have been synthesized through 1,3-dipolar cycloaddition of an azomethine ylide generated from sarcosine and isatin with the dipolarophile 3-benzylidene-1-methyl-pyrrolidine-2,5-dione. their antibacterial activity was evaluated against bacillus subtilis ncim 2718, staphylococcus aureus ncim5021, salmonella typhi ncim2501, pseudomonas aeruginosa ncim 5029 and proteus vulgaris ncim2813 by two fold dilution method. compound 6e exhibits reasonably good activity a ...201020556891
generation of chitin-derived oligosaccharides toxic to pathogenic bacteria using chia74, an endochitinase native to bacillus demonstrate that an endochitinase (chia74) native to bacillus thuringiensis can be used to generate chitin-derived oligosaccharides (ogs) with antibacterial activity against a number of aetiological agents of disease, including bacteria that cause diarrhoeal and emetic syndromes in humans.201020557451
high prevalence and molecular characterization of extended-spectrum β-lactamase-producing proteus mirabilis strains in southern croatia.the aim of this study was to determine the prevalence and antibiotic resistance rates of extended-spectrum β-lactamase (esbl)-producing proteus mirabilis strains isolated from inpatients at the split university hospital (southern croatia) during a survey performed between 2005 and 2008. a total of 2152 consecutive isolates of p. mirabilis were isolated. the prevalence was 0.5 % in 2005 and increased significantly to 20.9 % by 2008. strains were most frequently isolated from urine (36.5 %) and br ...201020558587
performance of the oxoid m.i.c.evaluator strips compared with the etest assay and bsac agar dilution.the oxoid m.i.c.evaluator (m.i.c.e; thermo fisher scientific) comprises an antibiotic gradient on a plastic support. we compared its performance with etest--a similar product--using bsac agar dilution as a reference.201020562429
prevalence of asymptomatic bacteriuria in type 2 diabetic subjects with and without microalbuminuria.abstract:201020565718
antimicrobial susceptibility and beta-lactamase production of selected gram-negative bacilli from two croatian hospitals: mystic study results.the meropenem yearly susceptibility test information collection (mystic) programme is a global, longitudinal resistance surveillance network that monitors the activity of meropenem and compares its activity with other broadspectrum antimicrobial agents. we now report the antimicrobial efficacy of meropenem compared to other broad-spectrum agents within the selective gram-negative pathogen groups from two croatian hospitals investigated between 2002-2007. a total of 1510 gram-negative pathogens w ...201020566417
chromosomally encoded blacmy-2 located on a novel sxt/r391-related integrating conjugative element in a proteus mirabilis clinical isolate.integrating conjugative elements (ices) are mobile genetic elements that can transfer from the chromosome of a host to the chromosome of a new host through the process of excision, conjugation, and integration. although sxt/r391-related ices, originally demonstrated in vibrio cholerae o139 isolates, have become prevalent among v. cholerae isolates in asia, the prevalence of the ices among gram-negative bacteria other than vibrio spp. remains unknown. in addition, sxt/r391-related ices carrying g ...201020566768
synthesis and antimicrobial activities of some quaternary morpholinium chlorides.the synthesis and antimicrobial activity of 31 morpholinium chlorides, divided into five series depending on the substituents attached to the nitrogen atom, n-carboxyalkyl-morpholinium chlorides (1a-e), n-carbalkoxymethyl-n-methyl-morpholinium chlorides (2a-f), n-carbethoxymethyl-n-alkyl-morpholinium chlorides (3a-g), n-carbalkoxymethyl-n-dodecyl-morpholinium chlorides (4a-f) and n-carboxymethyl-n-alkyl-morpholinium chlorides (5a-g) is reported. the compounds investigated were tested for antimic ...201020568530
chemical composition of the sfe-co extracts from cajanus cajan (l.) huth and their antimicrobial activity in vitro and in vivo.the in vitro and in vivo antimicrobial activities of sfe-co₂(supercritical fluid extraction) extracts and ethanol extracts from cajanus cajan (l.) huth were investigated. the flavonoid compounds orientin, vitexin, isovitexin, pinostrobin and the stilbene cajaninstilbene acid were detected in sfe-co₂ extracts by hplc-dad. in vitro antimicrobial activities of the extracts were evaluated against eight microbial strains (the bacteria staphylococcus epidermidis, staphylococcus aureus, bacillus subtil ...201020576412
synthesis, antibacterial activity evaluation and qsar studies of novel dispiropyrrolidines.a series of novel dispiropyrrolidines have been synthesized through 1,3-dipolar cycloaddition of an azomethine ylide generated from sarcosine and isatin with the dipolarophile 3-benzylidene-1-methyl-pyrrolidine-2,5-dione. their antibacterial activity was evaluated against bacillus subtilis ncim 2718, staphylococcus aureus ncim5021, salmonella typhi ncim2501, pseudomonas aeruginosa ncim 5029 and proteus vulgaris ncim2813 by two fold dilution method. compound 6e exhibits reasonably good activity a ...201020580853
molecular and genetic analyses of the putative proteus o antigen gene locus.proteus species are well-characterized opportunistic pathogens primarily associated with urinary tract infections (uti) of humans. the proteus o antigen is one of the most variable constituents of the cell surface, and o antigen heterogeneity is used for serological classification of proteus isolates. even though most proteus o antigen structures have been identified, the o antigen locus has not been well characterized. in this study, we identified the putative proteus o antigen locus and demons ...201020581173
antibiotic resistance of gram negative bacilli strains isolated from the intensive care unit in fundeni clinical institute, bucharest, romania.the aim of this study was to investigate the antibiotic resistance profile of 58 gram negative bacilli strains (gnb): 36 non-fermentative gnb (ngnb), including 19 strains of acinetobacter spp., 11 of pseudomonas aeruginosa, 6 of stenotrophomonas maltophilia and 22 enterobacterial strains (14 strains of kehss, 6 belonging to the group proteus-providencia and 2 escherichia coli) isolated from nasal, pharyngeal exudates and also from bronchial secretions, from immuno-depressed patients admitted in ...200920583477
[dynamics of acquires resistance in the main gramnegative pathogens of surgical infections to beta-lactams in 2004-2008].resistance of 2134 clinical isolates of etiologically significant species of gramnegative bacteria to 5 beta-lactam antibiotics, i. e. cefepime, piperacillin/tazobactam, cefoperazone/sulbactam, imipenem and ceftazidime (the 3rd generation cephalosporin) as the reference drug was investigated for the period of 5 years (2004-2008). in total, 554 strains of e. coli, 578 strains of p. aeruginosa, 255 strains of acinetobacter spp., 161 strains of proteus mirabilis, 359 strains of klebsiella pneumonia ...201020583554
synthesis and biological activities of novel amine-derived bis-azoles as potential antibacterial and antifungal agents.a series of novel amine-derived bis-azole compounds were designed by the systematical structural modification of fluconazole and synthesized by a convenient and efficient method, and the antimicrobial activities for all prepared compounds were evaluated in vitro against six representative bacterial strains and two fungal strains. bioactive results indicated that some synthesized compounds exhibited moderate or even better activities in comparison with the reference drugs. especially, bis-imidazo ...201020598399
in vitro bactericidal activity of human beta-defensin 2 against nosocomial strains.human beta-defensin 2 (hbd-2) is a 41-amino acid cationic peptide of the innate immune system that serves as antimicrobial molecule. we determined the bactericidal activity of synthetic hbd-2 against nosocomial strains belonging to eight different bacterial species and exhibiting various antimicrobial resistance phenotypes. the native disulfide connectivity was found essential for the bactericidal activity of hbd-2, while sodium chloride concentration was reversely associated with its potency. h ...201020600430
selective strategy for urethral catheterization in febrile young girls to confirm urinary tract infection diagnosis.urinary tract infections (utis) are a common source of bacterial infections in childhood. making a proper diagnosis is important but requires invasive urine collection techniques. we aimed to derive a clinical decision rule to identify non-toilet-trained febrile girls at high risk for utis to restrict urethral catheterizations (ucs) to this high-risk group of patients.201020606484
[nosocomial infections at clinical centre in kragujevac--prevalence study].nosocomial infections (nis) are a serious health problem in hospitals worldwide and are followed by a series of consequences, medical, judicial, ethical and economic.201020607980
clove syndrome with nevus unis lateris: report of a case.congenital lipomatous overgrowth, vascular malformations, and epidermal nevi (clove) syndrome is a recently described syndrome similar to proteus syndrome but lacking the progressive or distorting bony overgrowth of proteus syndrome. we describe a neonate with features of clove syndrome and nevus unius lateris.201020609160
rapidly spreading ctx-m-type beta-lactamase-producing proteus mirabilis in recent years, increased isolation of extended-spectrum beta-lactamase (esbl)-producing proteus mirabilis has been reported in japan. we undertook an investigation to determine the prevalence of esbl-producing p. mirabilis isolated in japan and to characterise the genotype. seventy-four p. mirabilis isolates recovered from specimens at 54 hospitals in japan between march and october 2006 were included in the study. of the 74 p. mirabilis isolates examined, 28 (37.8%) were esbl-producers. the b ...201020609568
laboratory surveillance for prospective plasmid-mediated ampc beta-lactamases in the kinki region of japan.extended-spectrum beta-lactamases, plasmid-mediated ampc beta-lactamases (pabls), and plasmid-mediated metallo-beta-lactamases confer resistance to many beta-lactams. in japan, although several reports exist on the prevalence of extended-spectrum beta-lactamases and metallo-beta-lactamases, the prevalence and characteristics of pabls remain unknown. to investigate the production of pabls, a total of 22,869 strains of 4 enterobacterial species, escherichia coli, klebsiella pneumoniae, klebsiella ...201020610688
chemical composition and biological activities of santiria trimera (burseraceae) essential oils from gabon.water-distilled essential oils from leaves and bark of santiria trimera (oliv.) aubrév. (burseraceae) collected in gabon were analyzed using capillary gc-fid and gc-ms. the leaf essential oil, which is described for the first time, was dominated by sesquiterpenes (76.5%), among which alpha-humulene (34.6%) and beta-caryophyllene (14.9%) were the major components. the bark essential oil was almost exclusively monoterpenic, with alpha-pinene (51.5%) and alpha-terpineol (16.8%) as main constituents ...201020614835
isoprenoid metabolism as a therapeutic target in gram-negative pathogens.gram-negative enterobacteria include a variety of human pathogens, perhaps most notably e. coli, salmonella, shigella, yersinia, and proteus. while there are treatment options for the diseases caused by these organisms, multi-drug resistance is often a problem and development of novel antibiotics has lagged over recent years. in humans, the isoprenoid biosynthetic pathway has become a subject of intense research for therapeutic modulation of human enzymes in diseases including hypercholesterolem ...201020615187
functional identification of the proteus mirabilis core lipopolysaccharide biosynthesis this study, we report the identification of genes required for the biosynthesis of the core lipopolysaccharides (lpss) of two strains of proteus mirabilis. since p. mirabilis and klebsiella pneumoniae share a core lps carbohydrate backbone extending up to the second outer-core residue, the functions of the common p. mirabilis genes was elucidated by genetic complementation studies using well-defined mutants of k. pneumoniae. the functions of strain-specific outer-core genes were identified by ...201020622068
rapid paper disk test for identification of helicobacter pylori in mixed cultures of gerbil gastric homogenates.a method denominated rapid paper disk test (rpdt) was developed to identify h. pylori colonies in complex cultures obtained from gerbil gastric homogenates. identification is based on a characteristic reaction pattern (rp) for h. pylori colonies given by the combination of the urease-oxidase activities on a paper disk. compared to the rps obtained from gerbil's intestinal tract isolated bacteria, h. pylori rp is completely distinguishable, even from those of bacteria that share one or both activ ...201020624429
history of polish neurology and neurosurgery. brudziński, jósef . 201020625969
aerobic bacteria from mucous membranes, ear canals, and skin wounds of feral cats in grenada, and the antimicrobial drug susceptibility of major a 2-year period 54 feral cats were captured in grenada, west indies, and a total of 383 samples consisting of swabs from rectum, vagina, ears, eyes, mouth, nose and wounds/abscesses, were cultured for aerobic bacteria and campylobacters. a total of 251 bacterial isolates were obtained, of which 205 were identified to species level and 46 to genus level. a commercial bacterial identification system (api/biomerieux), was used for this purpose. the most common species was escherichia coli (n=60) ...201120627391
antibiotic susceptibility of urogenital microbial profile of infertile men in south-eastern nigeria.male factors are known to contribute significantly to the infertility problem. the urogenital bacteria profile and semen quality were investigated among 160 men attending infertility clinics in south-eastern nigeria. both semen and urine samples were obtained from each subject and analysed according to standard techniques. a total of 16 (10%) had bacterial infection in their semen samples and individuals of older age groups were significantly affected (chi(2) = 23.18, p < 0.05). urinary tract in ...201020629651
ictal spect with mri fusion localizing a seizure focus in child with hemimegalencephaly and proteus syndrome. 201020631524
spread of odontogenic infections in port harcourt, nigeria.odontogenic infections constitute a substantial portion of diseases encountered by oral and maxillofacial surgeons. infections start from dental tissues and sometimes rapidly spread to contiguous spaces. the consequence is a fulminant disease with significant morbidity and mortality. the study was aimed at studying the pattern of spread, approach to management, and outcome of these infections at a nigerian teaching hospital.201020633973
survival of campylobacter jejuni under conditions of atmospheric oxygen tension with the support of pseudomonas spp.campylobacter jejuni is a major food-borne pathogen. despite causing enteritis in humans, it is a well-adapted intestinal microorganism in animals, hardly ever generating disease symptoms. nevertheless, as a true microaerophilic microorganism it is still puzzling how campylobacter cells can survive on chicken meat, the main source of human infection. in this study, we demonstrate that c. jejuni is able to withstand conditions of atmospheric oxygen tension when cocultured with pseudomonas species ...201020639377
[outbreak of diarrhea by rotavirus in bom jesus city, piauí state].this study focused a diarrhea outbreak caused by rotavirus in a city of piauí state aiming to identify the etiology, protocol of assistance to cases. a case series was carried out with 22 children assisted for acute diarrhea in 2006 in health units of bom jesus city. the data were collected by means of interviews utilizing forms that were with the help of the children's parents and analysis of the appointment files was performed. most of the families (59.1%) had a monthly income inferior to the ...201020640260
antibacterial activity of extracts from plants of central argentina--isolation of an active principle from achyrocline satureioides.the great increase in bacterial infections is fueling interest in the search for antibacterial products of plant origin. extracts obtained from 51 native and naturalized plants from central argentina were therefore evaluated for their in vitro inhibitory activity on pathogenic bacteria with the aim of selecting the most active ones as new sources of effective antibiotics. the susceptibility of reference and clinical strains of enterococcus faecalis, escherichia coli, proteus mirabilis, pseudomon ...201120645245
antimicrobial susceptibility of bacteria isolated from inpatients and outpatients urine samples.antibacterial resistance is generally regarded as a public health problem, not only in local terms, but also worldwide. the objective of this research work would be to analyze inpatient's and outpatient's antimicrobial resistance to a set of various agents. the patients have been medically treated in the region of ze-do canton since 2005 until today. total number of 164 patients was included in our research. regarding the place of medical treatment, our patients were divided into two groups: a t ...201020645510
host-pathogen interactions in urinary tract infection.the urinary tract is a common site of bacterial infections; nearly half of all women experience at least one urinary tract infection (uti) during their lifetime. these infections are classified based on the condition of the host. uncomplicated infections affect otherwise healthy individuals and are most commonly caused by uropathogenic escherichia coli, whereas complicated infections affect patients with underlying difficulties, such as a urinary tract abnormality or catheterization, and are com ...201020647992
extreme lifespan of the human fish (proteus anguinus): a challenge for ageing mechanisms.theories of extreme lifespan evolution in vertebrates commonly implicate large size and predator-free environments together with physiological characteristics like low metabolism and high protection against oxidative damages. here, we show that the 'human fish' (olm, proteus anguinus), a small cave salamander (weighing 15-20 g), has evolved an extreme life-history strategy with a predicted maximum lifespan of over 100 years, an adult average lifespan of 68.5 years, an age at sexual maturity of 1 ...201120659920
characterization of the hydrophobic substrate-binding site of the bacterial beta class glutathione transferase from proteus mirabilis.since their discovery, bacterial glutathione (gsh)transferases have been characterized in terms of their ability to catalyse a variety of different reactions on a large set of toxic molecules of xenobiotic or endobiotic origin. furthermore the contribution of different residues in the gsh-binding site to gsh activation has been extensively investigated. little is known, however, about the contribution to catalysis and overall stability of single residues shaping the hydrophobic co-substrate bind ...201020663851
density functional theory determination of structural and electronic properties of struvite.crystallographic structure, total energy, electronic structure, and the most important elastic properties of struvite, nh(4)mgpo(4).6h(2)o, the main component of infectious urinary stones, are presented. the calculations were performed using ab initio full-electron calculations within the density functional theory-generalized gradient approximation (dft-gga) framework. the obtained crystallographic symmetry and the calculated lattice parameters and also the elastic constants are in good agreemen ...201020666393
surface bacteriology of venous leg ulcers and healing outcome.bacteria can be cultured from all venous leg ulcers (vlus) regardless of healing status, and the significance of a positive swab result in non-clinically infected ulcers is unknown. the aim of this study was to characterise the bacteriological flora of vlus by routine culture to determine whether the data generated had prognostic value.201020671048
production of biogenic amines "in vitro" in relation to the growth phase by enterobacteriaceae species isolated from traditional sausages.histidine, lysine, ornithine and tyrosine decarboxylase activities were tested in 79 strains of enterobacteriaceae (41 of hafnia alvei, 17 of serratia liquefaciens, 5 of enterobacter cloacae, 4 of citrobacter braakii, 2 of proteus vulgaris, 2 of proteus mirabilis, 2 of providencia stuartii, 2 of klebsiella terrigena, 1 of rahnella aquatilis, 1 of salmonella arizonae, 1 of citrobacter youngae and 1 of escherichia coli) isolated from botillo, a spanish traditional sausage. in general, the strains ...201020673614
european clinical isolate of proteus mirabilis harbouring the salmonella genomic island 1 variant sgi1-o. 201020682564
computer-aided optimization of phosphinic inhibitors of bacterial ureases.urease inhibitors can be considered as a tool to control the damaging effect of ureolytic bacteria infections in humans which occur commonly in the developed countries. computer-aided optimization of the aminomethylphosphinate structures by modifying both their n- and p-termini led to the invention of a novel group of inhibitors of bacterial ureases. introduction of p-hydroxymethyl group into the molecule resulted in considerable increase of the inhibitory activity against enzymes purified from ...201020684601
electrical microcurrent to prevent conditioning film and bacterial adhesion to urological stents.long-term catheters remain a significant clinical problem in urology due to the high rate of bacterial colonization, infection, and encrustation. minutes after insertion of a catheter, depositions of host urinary components onto the catheter surface form a conditioning film actively supporting the bacterial adhesion process. we investigated the possibility of reducing or avoiding the buildup of these naturally forming conditioning films and of preventing bacterial adhesion by applying different ...201120686759
[cloning and expression of non-position-specific lipase gene from proteus vulgaris].to produce proteus vulgaris lipase (pvl) in large quantities, we cloned and expressed the lipase gene in escherichia coli.201020687340
[evaluation of the antimicrobial susceptibility profile of microorganisms isolated from urine in the region of vale do sousa and tâmega].the urinary tract is one of the more common sites of bacterial infections, especially in women. urinary infection can be defined as an infection of urinary tract structures which occurs, generally, as a consequence of the presence or colonization by urine bacteria. the aim of this study was to determine the etiology of urinary tract infections and their susceptibility to antimicrobial agents in the region of vale do sousa and tâmega. from february 2008 to january 2009, 18653 urine cultures were ...201020687992
microorganisms associated with maari, a baobab seed fermented product.a microbiological study was carried out on baobab fermented seeds (maari) obtained from 4 different production sites in burkina faso (mansila, toulfé, ouagadougou and gorgadji). a total of 390 representative isolates comprising 251 aerobic mesophilic bacteria (amb) and 139 lactic acid bacteria (lab) were isolated and identified to species level using a combination of pheno- and genotypic methods including conventional morphological analysis, carbohydrate fermentation profiling, rep-pcr ((gtg)(5) ...201020688411
in vitro multicompartmental bladder model for assessing blockage of urinary catheters: effect of hydrogel coating on dynamics of proteus mirabilis investigate the effect of a hydrogel coating on the dynamics of bacterial growth in laboratory models of the catheterized bladder. infection of the urinary tract by proteus mirabilis can result in catheter blockage by crystalline biofilm, a common complication in patients undergoing long-term bladder catheterization.201020696356
[characteristic features of urinary tract infection in malnourished children].the aim of this study is to prove a relationship between urinary tract infection and malnutrition in children 0-3 years old, hospitalized in the ivi pediatric clinic, hospital st. mary iaşi, between january 2000 and december 2004.201020700977
prevalence of extended-spectrum beta-lactamase-producing enterobacteriaceae in determine the occurrence of extended-spectrum beta-lactamase (esbl)-producing enterobacteriaceae in bahrain.200920701872
screening of antibacterial activity of mucus extract of snakehead fish, channa striatus (bloch).the objective of this study is to gain a better understanding of the antimicrobial properties of the mucus extract of snakehead fish, channa striatus against selected human and fish pathogenic microbes.201020707287
lycopersicon esculentum seeds: an industrial byproduct as an antimicrobial agent.lycopersicon esculentum (tomato) fruit is a widely studied matrix. however, only few works focus their attention on its seeds, which constitute a major byproduct of the tomato processing industry. in this study the antimicrobial potential of ten different tomato seed extracts from "bull's heart" and "cherry" varieties were analyzed against gram-positive (staphylococcus aureus, staphylococcus epidermidis, micrococcus luteus, enterococcus faecalis and bacillus cereus) and gram-negative (proteus mi ...201020707344
progressive overgrowth of the cerebriform connective tissue nevus in patients with proteus syndrome.proteus syndrome is a rare overgrowth disorder that almost always affects the skin.201020709429
phylogenetic analysis of the genera proteus, morganella and providencia by comparison of rpob sequences of type and clinical strains suggests the classification of proteus myxofaciens in a new genus cosenzaea gen. nov., as cosenzaea myxofaciens comb. nov.phylogenetic analysis of partial rpob gene sequences of type and clinical strains belonging to different 16s rrna gene-fingerprinting ribogroups within 11 species of enterobacteria of the genera proteus, morganella, and providencia allowed to define rpob clades supported by high bootstrap values and confirmed by >/=2.5% nucleotide divergence. no rpob clade included strains belonging to different species and the majority of the species were confirmed as discrete and homogeneous, since they consti ...201020709916
seasonal variation, chemical composition, and analgesic and antimicrobial activities of the essential oil from leaves of tetradenia riparia (hochst.) codd in southern brazil.the seasonal variation of the chemical composition of the essential oil from fresh leaves of tetradenia riparia (hochst.) codd grown in southern brazil was analyzed by gc-ms, and the analgesic and antimicrobial activities of this oil were assayed. the yield of essential oil ranged from 0.17% to 0.26%, with the maximum amount in winter and the minimum in spring. the results obtained from principal components analysis (pca) revealed the existence of high chemical variability in the different seaso ...201020714310
failure of tigecycline to treat severe clostridium difficile infection.clostridium difficile infection is an emerging and often difficult-to-treat iatrogenic complication. recent data suggest that tigecycline, a novel antibiotic with broad-spectrum antibacterial activity, can be used successfully to treat patients with severe clostridium difficile infection. we report a 70-year-old man who developed severe clostridium difficile infection, was admitted to the intensive care unit and eventually succumbed to complications of his illness despite receiving tigecycline f ...201020715744
efficacy and safety of moxifloxacin in uncomplicated pelvic inflammatory disease: the monalisa evaluate the efficacy and safety of moxifloxacin versus levofloxacin plus metronidazole in uncomplicated pelvic inflammatory disease (upid) in asia.201020716255
antibiotic producing potentials of three freshwater actinomycetes isolated from the eastern cape province of south africa.crude extracts of three actinomycetes species belonging to saccharopolyspora (tr 046 and tr 039) and actinosynnema (tr 024) genera were screened for antibacterial activities against a panel of several bacterial strains. the extracts showed antibacterial activities against both gram-negative and gram-positive test bacteria with inhibition zones ranging from 8 to 28 mm (tr 046); 8 to15 mm (tr 039); and 10 to 13 mm (tr 024). the minimum inhibitory concentrations ranged from 0.078 to 10 mg/ml (tr 04 ...201020717525
[analysis of drug resistance and risk factors of enterobacteriaceae in burn units].to study the risk factors of infection of extended-spectrum beta-lactamases (esbl)-producing strains and drug resistance of enterobacteriaceae that infected burn patients.201020723421
identification and characterization of a phospholipase a2 from the venom of the saw-scaled viper: novel bactericidal and membrane damaging activities.phospholipase a(2) (pla(2)), a common toxic component of snake venom, has been implicated in various pharmacological effects. in this study, a basic myotoxic pla(2), named ectx-i was isolated from echis carinatus snake venom by using gel filtration on superdex g-75, and reverse phase hplc on c18 and c8 sepharose columns. pla(2), ectx-i was 13,861.72 molecular weight as estimated by maldi-tof (15 kd by sds-page), and consisted of 121 amino acid residues cross-linked by seven disulfide bonds. the ...201020723574
inferring the demographic history of the adriatic flexopecten complex.phylogenetic analysis of dna sequences can be a useful tool in taxonomical studies, which has important implications in terms of species traceability. the aim of our study is to solve the controversy regarding the taxonomical status of the flexopecten group, which includes two putative sister species (f. glaber and f. proteus) that co-occur in the adriatic sea and are clearly distinguishable on the basis of morphometric characters. our molecular analysis using three mitochondrial genes (coi, 12s ...201020723607
[effect of methods of application of bacterial ligands on activation of lymphoid organs' effectors in mice].evaluation of differentiation dynamics and localization of various populations of lymphocytes as well as their expression of tlrs during different methods of administration (intranasal, oral, and subcutaneous) of bacterial ligands of opportunistic microorganisms (immunovac-vp-4 vaccine) in experiment on mice.201020737684
on the anaesthetic properties of the lycoperdon proteus, or common puff-ball. 185320740850
gastro-enteritis associated with proteus vulgaris. 193720780637
proteus vulgaris septicaemia treated with penicillin. 194620786773
successful treatment of a case of proteus septicaemia. 196220789534
purple urine bag syndrome. 201020798099
suprathel-acetic acid matrix versus acticoat and aquacel as an antiseptic dressing: an in vitro study.the treatment of burn wounds is still a challenge regarding the management of antiseptic wound conditioning. especially, in the united states, silver-containing dressings, such as acticoat and aquacel are frequently used. because silver-containing dressings have well-known drawbacks such as an antimicrobial lack against pseudomonas aeruginosa, we sought to develop an alternative dressing method. in previous studies, we could demonstrate the excellent antiseptic properties of acetic acid against ...201020798627
[immunovac-vp4 vaccine used in complex allergen-specific immunotherapy of patients with hay fever].assessment of clinical and immunological effects of use of bacterial therapeutic polycomponent vaccine immunovac-vp4 for allergen-specific immunotherapy (asit) of hay fever.201020799399
cajanol inhibits the growth of escherichia coli and staphylococcus aureus by acting on membrane and dna the present study, the mechanism of antibacterial activity of cajanol extracted from the roots of cajanus cajan (l.) millsp. towards escherichia coli (e. coli) and staphylococcus aureus (s. aureus) was investigated. the antibacterial activity of cajanol was evaluated towards six bacterial strains (staphylococcus epidermidis, staphylococcus aureus, bacillus subtilis, escherichia coli, proteus vulgaris, and pseudomonas aeruginosa) by the broth microdilution method. it showed strong antibacteria ...201120803417
adhesion, invasion, and agglutination mediated by two trimeric autotransporters in the human uropathogen proteus mirabilis.fimbriae of the human uropathogen proteus mirabilis are the only characterized surface proteins that contribute to its virulence by mediating adhesion and invasion of the uroepithelia. pmi2122 (aipa) and pmi2575 (taap) are annotated in the genome of strain hi4320 as trimeric autotransporters with "adhesin-like" and "agglutinating adhesin-like" properties, respectively. the c-terminal 62 amino acids (aa) in aipa and 76 aa in taap are homologous to the translocator domains of yada from yersinia en ...201020805336
synthesis and spectrum of the neoglycoside achn-490.achn-490 is a neoglycoside, or "next-generation" aminoglycoside (ag), that has been identified as a potentially useful agent to combat drug-resistant bacteria emerging in hospitals and health care facilities around the world. a focused medicinal chemistry campaign produced a collection of over 400 sisomicin analogs from which achn-490 was selected. we tested achn-490 against two panels of gram-negative and gram-positive pathogens, many of which harbored ag resistance mechanisms. unlike legacy ag ...201020805391
mucinous cystadenoma of ovary in a patient with juvenile polyposis due to 10q23 microdeletion: expansion of phenotype.juvenile polyposis syndrome (jps) is a hereditary condition characterized by development of gastrointestinal polyps, and caused by mutations in smad4 or bmpr1a genes. juvenile polyps can also be found in a related group of syndromes with multisystemic involvement including cowden disease, lhermitte-duclos disease, bannayan-riley-ruvalcaba syndrome, and proteus-like syndrome, all grouped as pten hamartoma tumor syndromes (phts). in all these conditions including jps, polyps manifest in older chil ...201020815035
prevalence of microorganisms of hygienic interest in an organized abattoir in mumbai, india.the magnitude of food-borne illnesses in india is unknown because of lack of surveillance networks. monitoring the prevalence of food-borne pathogens and indicators of contamination in primary production at abattoirs is imperative for creating a data bank and for effective control of such pathogens before they enter the food chain.201020818094
[epidemiology of urinary tract infection in children in marrakech].by its incidence, the polymorphism of its clinical presentation, its potential gravity, the difficulty of realization of urine culture in children, the frequency of the subjacent urologic abnormalities, the urinary tract infection (uti) is an important problem in paediatrics. this work relates to a retrospective study carrying 121 episodes of uti in 111 children taken care in paediatrics services of the teaching hospital mohammed vi in marrakech between march 2005 and march 2009. the age of our ...201020826328
template-based modeling of a psychrophilic lipase: conformational changes, novel structural features and its application in predicting the enantioselectivity of lipase catalyzed transesterification of secondary order to fully explore the structure-function relationship of a proteus lipase (lipk107) that was screened from the soil in our previous study, we have modeled the three-dimensional (3-d) structures of the enzyme in its active and inactive conformations on the basis of crystal structures of burkholderia glumae and pseudomonas aeruginosa lipases in the present study. both homology models suggested that lipk107 possessed a catalytic triad (ser79-asp232-h254), an oxyanion hole (leu13 and gln80) ...201020828637
structural basis of na(+)-independent and cooperative substrate/product antiport in cait.transport of solutes across biological membranes is performed by specialized secondary transport proteins in the lipid bilayer, and is essential for life. here we report the structures of the sodium-independent carnitine/butyrobetaine antiporter cait from proteus mirabilis (pmcait) at 2.3-a and from escherichia coli (eccait) at 3.5-a resolution. cait belongs to the family of betaine/carnitine/choline transporters (bcct), which are mostly na(+) or h(+) dependent, whereas eccait is na(+) and h(+) ...201020829798
bacterial contamination of ram semen, antibiotic sensitivities, and effects on sperm quality during storage at 15°c.this study was designed to determine the degree and type of bacterial contamination of ejaculated semen samples in fertile rams and its consequences on sperm quality during storage. in experiment 1, 68 ejaculates from 36 rams were divided into two aliquots, one of which was used for bacterial culture, while the other one was diluted, stored at 15°c and assessed for plasma membrane integrity and motility at 0, 24 and 48h after dilution. from the 68 ejaculates, 66 were positive for aerobic bacteri ...201020832206
decolorization and biodegradation of reactive blue 13 by proteus mirabilis lag.the decolorization and biodegradation of reactive blue 13 (rb13), a sulphonated reactive azo dye, was achieved under static anoxic condition with a bacterial strain identified as proteus mirabilis lag, which was isolated from a municipal dump site soil near lagos, nigeria. this strain decolorized rb13 (100mg/l) within 5h. the formation of aromatic amine prior to mineralization was supported by fourier transform infrared spectrometry (ftir), which revealed the disappearance of certain peaks, part ...201020832936
enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis.disruption of homeostasis between the host immune system and the intestinal microbiota leads to inflammatory bowel disease (ibd). whether ibd is instigated by individual species or disruptions of entire microbial communities remains controversial. we characterized the fecal microbial communities in the recently described t-bet(-/-) ×rag2(-/-) ulcerative colitis (truc) model driven by t-bet deficiency in the innate immune system. 16s rrna-based analysis of truc and rag2(-/-) mice revealed distinc ...201020833380
screening of the constituents, antimicrobial and antioxidant activity of endemic origanum hypericifolium o. schwartz & p.h. davis.the chemical compositions, total phenol content, antioxidant and antimicrobial activities with oxidant status of the essential oil from an endemic turkish species, origanum hypericifolium, were investigated. steam distillation (sd) was used to isolate the essential oils, and the chemical analyses were performed by gas chromatography-mass spectrometry (gc-ms). the antimicrobial activity was tested by agar disc diffusion method against morganella morganii (clinic isolate), micrococcus flavus (clin ...201020835958
antibacterial activity of some medicinal mangroves against antibiotic resistant pathogenic bacteria.the antibacterial activity of the leaves and bark of mangrove plants, avicennia marina, a. officinalis, bruguiera sexangula, exoecaria agallocha, lumnitzera racemosa, and rhizophora apiculata was evaluated against antibiotic resistant pathogenic bacteria, staphylococcus aureus and proteus sp. soxhlet extracts of petroleum ether, ethyl acetate, ethanol and water were prepared and evaluated the antibacterial activity using agar diffusion method. most of the plant extracts showed promising antibact ...201020838519
preliminary phytochemical screening and antimicrobial studies of lantana indica roxb.the aim of the present study was to investigate the antimicrobial and preliminary phytochemical properties of lantana indica roxb. the aqueous and organic solvent (ethyl acetate and methanol) extracts from the leaves of lantana indica (verbenaceae) were tested against staphylococcus aureus, bacillus subtilis, steptococcus pyrogens, escherichia coli, proteus vulgaris, klebsiella pneumoniae, pseudomonas aeruginosa, salmonella typhi, aspergillus niger and candida albicans by agar well diffusion met ...201020838528
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