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polyoxygenated methyl cyclohexanoids from a terrestrial ampelomyces fungus.seven structurally related new polyoxygenated methyl cyclohexanoids, ampelomins a-g (1-7), were isolated from the mycelial solid culture of a soil-derived ampelomyces fungus. their structures were determined by spectroscopic and chemical means. ampelomins a (1), c (3), e (5), and g (7) exhibited weak activity against alpha-glucosidase with ic(50) values of 1.74-5.93 mm, and ampelomin a (1) showed moderate antibacterial activity with mic(90) values ranging from 202.4 to 1015.9 microm. a plausible ...200919193024
significance of the cyclic structure and of arginine residues for the antibacterial activity of arenicin-1 and its interaction with phospholipid and lipopolysaccharide model membranes.arenicin-1 (ar-1) is a beta-sheeted antimicrobial peptide from the marine lugworm arenicola marina. to elucidate the significance of its unique 18-residue cyclic structure and of six cationic arginines for its biological activity and its interaction with biomembranes, we synthesized one linear peptide in which the two cysteines were exchanged for serines (c/s-ar-1) and a cyclic peptide in which all arginines were replaced by lysines (r/k-ar-1). we addressed antibacterial and hemolytic activities ...200919199831
isolation and identification of antibacterial compounds from thymus kotschyanus aerial parts and dianthus caryophyllus flower buds.the aerial parts of thymus kotschyanus boiss. and hohen. (lamiaceae) and flower buds of dianthus caryophyllus l. (caryophyllaceae) have been traditionally implemented in the treatment of wounds, throat and gum infections and gastro-intestinal disorder by the indigenous people of northern iraq, although the compounds responsible for the medicinal properties have not been identified. in this study, antibacterial compounds from both plants were isolated and characterized, and the biological activit ...200919200700
community-acquired urinary tract infections in southern turkey: etiology and antimicrobial resistance.in this study, we compared the distribution and antibiotic susceptibility patterns of bacterial strains isolated from patients with community-acquired urinary tract infections in southern turkey, hatay, during 2004 and 2005. the majority (82.3%) of the isolates were from women while the remaining (17.7%) were from men. of all samples tested, 49% were culture-positive with a bacterial pathogen. the most frequently isolated bacterial species were escherichia coli (45.1%), coagulase-negative staphy ...200919203547
antimicrobial activity of some macrophytes from lake manzalah (egypt).the antimicrobial activities of aqueous and organic solvents (chloroform, ethanol and methanol) extracts of four plants ceratophyllum demersum l., eichhornia crassipes, potamogeton crispus and potamogeton pectinatus were tested in vitro against seventeen different microorganisms including gram-positive and gram-negative bacteria and fungi. nine of these identified organisms were obtained from different sources, bacillus subtilis 1020, bacillus cereus 1080, staphylococcus aureus, erwinia carotovo ...200819205264
regioselective synthetic approaches towards 1,2,8,9-tetraazadispiro[4.1.4.2]trideca-2,9-dien-6-ones of potential antimicrobial properties.reaction of 2,5-bis(arylmethylidene)cyclopentanones 1a-d with nitrilimines (generated in situ via triethylamine dehydrohalogenation of the corresponding hydrazonoyl chlorides 2a,b) in 1:2 molar ratio proceeds in a high regioselective manner affording monocycloadducts 3 and dicycloadducts in the form of two isomers 4, 5. single crystal x-ray diffraction studies of the isolated crystalline form of 3c support the established structure and indicate that the formed product is 7e, 4s, 5r. antimicrobia ...200919211175
interaction of intracorporeal lithotripters with proteus mirabilis inoculated inside artificial calcium and struvite stones.renal calculi may contain bacteria that can remain active inside the stone and produce bacteremia and/or endotoxemia after lithotripsy. urinary tract infection associated with urinary stones represents high morbidity. the purpose of this research was to use novel artificial struvite stones inoculated with living bacteria and to study the effect of four different intracorporeal lithotripters on bacterial inactivation after in vitro lithotripsy.200919216637
[distribution and drug resistance analysis of bacteria in different wound infections].to analyze the distribution and drug resistance of bacteria in different wound infections and provide evidence for wound infection control in subtropical regions.200919218119
comparison of pcr-based molecular markers for the characterization of proteus mirabilis clinical isolates.proteus mirabilis is one of the most important pathogens associated with complicated urinary tract infections (acute pyelonephritis, bladder infections, kidney stones) and bacteremia, affecting patients with anatomical abnormalities, immunodeficiency, and long-term urinary catheterization. for epidemiological purposes, various molecular typing methods, such as pulse-field gel electrophoresis (pfge) or ribotyping, have been developed for this pathogen. however, these methods are labor intensive a ...200819219283
[occupational exposure to mesophilic microorganisms associated with commercial processing of compost for mushroom production].the aim of the study was to assess the occupational exposure to mesophilic microorganisms associated with commercial processing of compost for mushroom production.200819227882
needle puncture and transcutaneous bone biopsy cultures are inconsistent in patients with diabetes and suspected osteomyelitis of the foot.needle puncture has been suggested as a method for identifying bacteria in the bones in patients with diabetes with osteomyelitis of the foot. however, no studies have compared needle puncture with concomitant transcutaneous bone biopsy, which is the current standard recommended in international guidelines.200919228109
strongyloides stercoralis hyperinfection presenting as acute respiratory failure and gram-negative sepsis in a patient with astrocytoma.in developing countries, strongyloides stercoralis infection is a common cause of morbidity and mortality. death from strongyloidosis can result from hyperinfection or disseminated disease. infections due to s. stercoralis are unusual in saudi arabia and are usually diagnosed in immigrants from endemic areas. we report a case in which s. stercoralis was isolated from the sputum of a patient with gram-negative sepsis and respiratory failure, and review the salient features of this disease. a high ...200919231269
antimicrobial effects of propolis extracts on escherichia coli and staphylococcus aureus strains resistant to various antibiotics and some microorganisms.abstract propolis is collected by worker honey bees from the trees. the bees pack propolis on their hind legs, carry it to their colony, and use it as a sterilant in the hive. propolis has also been used by humans since early times for various purposes and, especially, as a medicine because of its antimicrobial properties. in this study, antimicrobial effects of propolis samples on three escherichia coli and two staphylococcus aureus strains that are multiresistant to antibiotics and on salmonel ...200019236174
antimicrobial susceptibility pattern of urinary tract pathogens.microbial drug resistance is a major problem in the treatment of infectious diseases worldwide. the purpose of this survey is to determine the prevalence of the type of bacterial agents that cause urinary infection and to assess the antimicrobial sensitivity pattern in the urmia medical university, iran. in the period between 2005 and 2006, urine cultures collected were analyzed. positive culture was defined as growth of a single bacterial species with colony count of > 100,000 cfu/ml. stratific ...200919237813
1h-nuclear magnetic resonance spectroscopy for identifying and quantifying common uropathogens: a metabolic approach to the urinary tract infection.to address the shortcomings of urine culture for the diagnosis of urinary tract infection (uti), we used 1h-nuclear magnetic resonance (nmr) spectroscopy for identifying and quantifying escherichia coli, pseudomonas aeruginosa, klebsiella pneumonia and proteus mirabilis.200919239442
tigecycline.infection with resistant pathogens can adversely affect clinical, microbiological and economic outcomes. new agents for the treatment of many such serious infections are acutely needed in hospital practice. tigecycline is a novel glycylcycline antimicrobial for intravenous use. it has an expanded broad-spectrum antibacterial activity including multi-drug resistant pathogens, like methicillin-resistant staphylococcus aureus , vancomycin-resistant enterococci , multi-drug resistant streptococcus p ...200919242083
proteus syndrome: high-resolution ct and ct pulmonary densitovolumetry findings.cystic transformation of the lungs in proteus syndrome is considered an important manifestation of this disease. we describe a case of an 11-year-old girl with a diagnosis of proteus syndrome with lung involvement. low-dose multidetector computed tomography (ct) revealed extensive diffuse cystic lung disease with left lung predominance, affecting mostly the lower lung zones. the cystic lesions had various sizes and variable wall thickness. postprocessing using ct histogram densitometric volumetr ...200919242304
doripenem activity tested against a global collection of enterobacteriaceae, including isolates resistant to other extended-spectrum agents.the emergence and rapid dissemination of extended-spectrum beta-lactamase (esbl)-producing isolates among enterobacteriaceae coupled with increasing prevalence of stably derepressed and plasmid-borne ampc producers have rendered broad-spectrum cephalosporins and beta-lactam/beta-lactamase inhibitor combinations less effective. this scenario has required the use of carbapenems for treatment of infections caused by such organisms. in this study, the in vitro activities of doripenem and comparator ...200919249175
characteristics and clinical significance of bacterial colonization of ureteral double-j stents in children.to determine the frequency, type of pathogen and clinical significance of bacterial colonization of double-j stents after pyeloplasty in children.200919251483
the dienes phenomenon: competition and territoriality in swarming proteus mirabilis.when two different strains of swarming proteus mirabilis encounter one another on an agar plate, swarming ceases and a visible line of demarcation forms. this boundary region is known as the dienes line and is associated with the formation of rounded cells. while the dienes line appears to be the product of distinction between self and nonself, many aspects of its formation and function are unclear. in this work, we studied dienes line formation using clinical isolates labeled with fluorescent p ...200919251852
pneumoureter. 200919254678
new plasmid-mediated quinolone resistance gene, qnrc, found in a clinical isolate of proteus mirabilis.since the discovery of qnra in 1998, two additional qnr genes, qnrb and qnrs, have been described. these three plasmid-mediated genes contribute to quinolone resistance in gram-negative pathogens worldwide. a clinical strain of proteus mirabilis was isolated from an outpatient with a urinary tract infection and was susceptible to most antimicrobials but resistant to ampicillin, sulfamethoxazole, and trimethoprim. plasmid phs10, harbored by this strain, was transferred to azide-resistant escheric ...200919258263
detection of bacterioplankton in immersed cadavers using selective agar plates.we measured bacterioplankton in blood from cadavers retrieved from the sea (n=12), near estuaries (n=4), rivers (fresh water, n=8) and from bathtubs (n=4) as well as from non-drowned victims (n=10) discovered near aquatic environments. blood from 11 victims drowned in seawater developed bioluminescent and/or blue colonies (oxidase test positive) on selective media containing 2-4% nacl. homology analyses of the 16s rrna gene showed that all of them were marine bacteria (genera: photobacterium, vi ...200919261520
[evaluation of the microscan negcombo panel type 44 for detection of extended-spectrum beta-lactamase among clinical isolates of escherichia coli, klebsiella species, and proteus mirabilis].accurate and rapid detection of extended-spectrum beta-lactamases (esbls) is important in guiding proper antimicrobial therapy for infected patients. we evaluated the performance of microscan negcombo type 44 panel (dade behring, usa), which was developed to confirm esbl-producing enterobacteriaceae using ceftazidime/clavulanate and cefotaxime/clavulanate.200919262076
antibacterial activities of crude extract of aloe barbadensis to clinically isolated bacterial pathogens.the antibacterial activity of aloe barbadensis was tested on clinically isolated bacterial pathogens i.e. enterococcus bovis, staphylococcus aureus, escherichia coli, proteus vulgaris, proteus mirabilis, pseudomonas aeruginosa, morganella morganii, and klebsiella pneumoniae causing infection in human being. ethanolic and aqueous extracts were used for the antibacterial effect, which was measured by the appearance of zone of inhibition. relatively higher mic concentrations were obtained for gram ...201019263248
piscidin 4, a novel member of the piscidin family of antimicrobial peptides.piscidins are linear, amphipathic, antimicrobial peptides (amps) with broad, potent, activity spectrum. piscidins and other members of the piscidin family appear to comprise the most common group of amps in teleost fish. all piscidins and related members of the piscidin family described to date are 18-26 amino acids long.we report here the isolation of a novel 5329.25 da, 44-residue (ffrhlfrgakaifrgarqgxrahkvvsryrnrdvpetdnnqeep) antimicrobial peptide from hybrid striped bass (morone chrysops fem ...200919266617
[clinical analysis of otogenic intracranial complications].to analyze the clinical features and treatment protocols of otogenic intracranial complications in peking union medical college hospital.200819267967
the effect of marigolds (tagetes spp.) and other cover crops on pratylenchus penetrans and on following potato crops.root-lesion nematodes (primarily pratylenchus penetrans) were monitored in two marigold cultivars (tagetes tenuifolia cv. nemakill and cv. nemanon), annual ryegrass (lolium multiflorum cv. lemtal), red clover (trifolium pratense cv. florex), and soybean (glycine max cv. proteus), and in the following potato (solanum tuberosum cv. superior) crop during three growth sequences. meadow fescue (festuca elatior cv. miner) and bee plant (phacelia tanacetifolia cv. gipha) were added to the trial in the ...200019271006
[a boy with abdominal pain and when urinating. urinary stones in a mega urethra]. 200919271445
growth inhibition of pathogenic bacteria and some yeasts by selected essential oils and survival of l. monocytogenes and c. albicans in apple-carrot juice.food safety is a fundamental concern of both consumers and the food industry. the increasing incidence of foodborne diseases increases the demand of using antimicrobials in foods. spices and plants are rich in essential oils and show inhibition activity against microorganisms, which are composed of many compounds. in this research, effects of garlic, bay, black pepper, origanum, orange, thyme, tea tree, mint, clove, and cumin essential oils on listeria monocytogenes aufe 39237, escherichia coli ...200919278342
[change of mating type induced by actinomycin d in the ciliate dileptus anser].effect of actinomycin d on the expression and inheritance of mating types (mts) in mature laboratory clones of the ciliate dileptus anser was studied. each mature clone of these ciliates isolated from natural population appears to belong to one of the three complementary mts - mt i, mt ii or mt iii. its mt does not vary in the course of further laboratory cultivation of the clone in a series of vegetative generations. however, after treatment with actinomycin d (15 microg/ml, 3 days), such clone ...200919281052
catheter-related urinary tract infection in patients suffering from spinal cord injuries.urinary tract infection is commoner in patients with spinal cord injuries because of incomplete bladder emptying and the use of catheters that can result in the introduction of bacteria into the bladder. 145 patients suffering from spinal cord injuries, admitted to the institute for physical medicine and rehabilitation, centre for paraplegia of the clinical centre of the university of sarajevo, were included. the patients were divided in three groups according to the method of bladder drainage: ...200919284388
surveillance of intrahospital infections at the clinic for gynaecology and obstetrics.intrahospital infections (ihi) and antibiotics resistance are the problems which exist in virtually all hospitals in the world. the main aim of the present research is establishing of epidemiological surveillance over occurrence of ihi at the clinic for gynaecology and obstetrics at the university clinical center tuzla and thus identifies: types of bacteria which cause ihi, types of infection according to anatomical localization and research resistance organisms causing of ihi on antimicrobial d ...200919284398
the antimicrobial effect of acetic acid--an alternative to common local antiseptics?acetic acid has been commonly used in medicine for more than 6000 years for the disinfection of wounds and especially as an antiseptic agent in the treatment and prophylaxis of the plague. the main goal of this study was to prove the suitability of acetic acid, in low concentration of 3%, as a local antiseptic agent, especially for use in salvage procedures in problematic infections caused by organisms such as proteus vulgaris, acinetobacter baumannii or pseudomonas aeruginosa. this study was de ...200919286325
micrornas and genomic variations: from proteus tricks to prometheus gift.micrornas (mirnas) are small non-coding rnas with regulatory functions. mirnas are aberrantly expressed in almost all human cancers, leading to abnormal levels of target genes. recently, an increasing number of studies have addressed whether genomic variations including germ line or somatic mutations and single-nucleotide polymorphisms can count for mirna abnormal expression by altering their biogenesis and/or affect the ability of mirnas to bind to target messenger rnas. here, we provide an ext ...200919293341
antibiotic susceptibility pattern of staphylococcus species isolated from telephone receivers.microorganisms are transferred to everyday objects from the environment and infected individuals. pathogenic microbes are transmissible from the air, skin, hands and other interpersonal contacts and cause diseases most of the time. this study centres on the microbial assessment of telephone receivers, their ability to transfer bacterial infections and the isolation of these microorganisms from receivers, with an emphasis on staphylococcus aureus and its antibiotic susceptibility pattern.200919296038
novel ctx-m {beta}-lactamase genotype distribution and spread into multiple species of enterobacteriaceae in changsha, southern china.the aim of this study was to undertake a survey of the occurrence of ctx-m and shv extended-spectrum beta-lactamase (esbl) genotypes in enterobacteriaceae from hunan province, china.200919297379
tamm-horsfall protein protects against urinary tract infection by proteus mirabilis.proteus mirabilis is a common cause of urinary tract infection. we determined the role of tamm-horsfall protein as a host defense factor against the cystitis and pyelonephritis caused by p. mirabilis.200919303096
growth inhibition of foodborne and pathogenic bacteria by conjugated linoleic acid.the influence of conjugated linoleic acid (cla) on the growth of some foodborne and pathogenic bacteria was examined. a potassium salt of cla (cla-k) was tested against three gram-positive strains ( bacillus cereus , staphylococcus aureus , and streptococcus mutans ) and five gram-negative strains ( pseudomonas aeruginosa , salmonella typhimurium , vibrio parahemolyticus , klebsiella pneumoniae , and proteus mirabilis ). cla-k-mediated growth inhibition was evident for all tested strains, partic ...200919317483
16s-23s rdna internal transcribed spacer regions in four proteus species.proteus is a gram-negative, facultative anaerobic bacterium. in this study, 813 proteus 16s-23s rdna internal transcribed spacer (its) sequences were determined from 46 proteus strains, including 388 its from 22 p. mirabilis strains, 211 its from 12 p. vulgaris strains, 169 its from 10 p. penneri strains, and 45 its from 2 p. myxofaciens strains. the proteus strains carry mainly two types of its, its(glu) (containing trna(glu (uuc)) gene) and its(ile+ala) (containing trna(ile (gau)) and trna(ala ...200919318046
laser interferometric and cultivation methods for measurement of colistin/ampicilin and saponin interactions with smooth and rough of proteus mirabilis lipopolysaccharides and cells.laser interferometry is commonly used in permeability studies of soluble substances. in this study a modification that allowed testing partially insoluble mixtures is presented. the modification relies on the measurement of diffusion from 1% agarose gel. as a model for this study, two proteus mirabilis strains were used that differ in polysaccharide content: smooth p. mirabilis s1959 strain and its re-type mutant, strain r45. by laser interferometry and precipitation it is shown that r45 lipopol ...200919318050
prevalence of multiresistant gram-negative organisms in a tertiary hospital in mwanza, tanzania.antimicrobial resistance is fast becoming a global concern with rapid increases in multidrug-resistant gram negative organisms. the prevalence of extended spectrum beta-lactamase (esbl)-producing clinical isolates increases the burden on implementing infectious disease management in low socio-economic regions. as incidence can vary widely between regions, this study was done to determine resistance patterns of gram-negative organisms at bugando medical center, a tertiary hospital in mwanza, tanz ...200919323805
eca-immunogenicity of proteus mirabilis strains.bacteria of the genus proteus are opportunistic pathogens and cause mainly urinary tract infections. they also play a role in the pathogenesis of reactive arthritis (ra). patients suffering from yersinia-triggered ra often carry high titers of antibodies specific to enterobacterial common antigen (eca). the immunogenicity of eca has not received much attention thus far and studies have focused mainly on the eca of escherichia coli and yersinia enterocolitica. in this paper the eca-immunogenicity ...200919333729
folate, cancer risk, and the greek god, proteus: a tale of two chameleons.evidence indicates that an abundant intake of foodstuffs rich in folate conveys protection against the development of colorectal cancer, and perhaps some other common cancers as well. the issue is complex, however, since some observations in animal and human studies demonstrate that an overly abundant intake of folate among those who harbor existing foci of neoplasia might instead produce a paradoxical promotion of tumorigenesis. the pharmaceutical form of the vitamin, folic acid, might affect t ...200919335714
lysozyme catalyzes the formation of antimicrobial silver nanoparticles.hen egg white lysozyme acted as the sole reducing agent and catalyzed the formation of silver nanoparticles in the presence of light. stable silver colloids formed after mixing lysozyme and silver acetate in methanol and the resulting nanoparticles were concentrated and transferred to aqueous solution without any significant changes in physical properties. activity and antimicrobial assays demonstrated lysozyme-silver nanoparticles retained the hydrolase function of the enzyme and were effective ...200919344124
colonization with multidrug-resistant gram-negative bacteria: prolonged duration and frequent cocolonization.the characteristics of colonization with multidrug-resistant gram-negative bacteria (mdrgnb) in the gastrointestinal tract have not been well defined. characterizing the duration of colonization, clearance of colonization, and frequency of cocolonization would provide important information for the development of interventions targeting the prevention of mdrgnb spread.200919348593
resin-salve from norway spruce--a potential method to treat infected chronic skin ulcers?the home-made resin salve from norway spruce is traditionally and widely used in folk medicine to heal various skin infections and wounds in northern finland. we have performed laboratory studies to solve the mechanism of resin salve. the resin salve exhibited a bacteriostatic effect against all tested gram-positive bacteria important in human medicine including methicillin-resistant staphylococcus aureus (mrsa) and vancomycin-resistant enterococcus (vre), but was not effective against gram-nega ...200719356034
bacterial indicators of pollution of the douala lagoon, cameroon: public health implications.indiscriminate disposal of untreated wastes which are often heavily laden with sewage microorganisms some of which are pathogenic to humans into aquatic environments near cities could serve as potential dangers to human health.200819357756
otogenic cerebellar abscess: a case report.this case report describes the gradual deterioration of a healthy, highly functioning man who initially presented with a draining right ear. the patient's indolent neurologic decline and referral to an otologist ultimately led to the diagnosis and treatment of an otogenic cerebellar abscess, an increasingly rare intracranial complication of otitis media. we report this case to illustrate that severe complications of chronic otitis media still occur in the united states, to stress the importance ...200919358116
proteus syndrome: report of a case with recurrent abdominal lipomatosis.proteus syndrome (ps) is an extremely rare congenital hamartomatous syndrome that was first delineated by cohen and hayden (1). the estimated prevalence is less than 1 per 1,000,000 live births (2). it is a sporadic disorder that causes overgrowth of multiple tissues, especially bone, fat, and other connective tissues in a patchy or mosaic pattern. subcutaneous as well as internal lipomas that may grow to an enormous size are frequently observed. nevertheless, among the internal lipomas, abdomin ...200919361616
[phosphatase activity in amoeba proteus at low ph].in free-living amoeba proteus (strain b), three forms of tartrate-sensitive phosphatase were revealed using page of the supernatant of ameba homogenates obtained with 1% triton x-100 or distilled water and subsequent staining of gels with 2-naphthyl phosphate as substrate (ph 4.0). the form with the highest mobility in the ameba supernatant was sensitive to all tested phosphatase activity modulators. two other forms with the lower mobilities were completely or significantly inactivated not only ...200919370987
the high-affinity phosphate transporter pst in proteus mirabilis hi4320 and its importance in biofilm formation.proteus mirabilis causes urinary tract infections (utis) in individuals requiring long-term indwelling catheterization. the pathogenesis of this uropathogen is mediated by a number of virulence factors and the formation of crystalline biofilms. in addition, micro-organisms have evolved complex systems for the acquisition of nutrients, including the phosphate-specific transport system, which has been shown to be important in biofilm formation and pathogenesis. a functional pst system is important ...200919372157
organisms associated with ventilator associated pneumonia in intensive care unit.it is a cross sectional observational study. place of study was the icu of square hospitals ltd. and icu of bangabandhu sheikh mujib medical university (bsmmu). all patients who were diagnosed as a case of ventilator associated pneumonia (vap) in icu during the one year study period (01.01.2006 to 31.12.2006) were included in this study. data was collected by patient's clinical register, checklist. total number of patients was 43. main objective of our study was to identify the organisms associa ...200919377438
overgrowth conditions: a diagnostic and therapeutic conundrum.over the past five decades, one of the major problems in the treatment of overgrowth syndromes of the hand has been classification. currently, a number of specific conditions with known natural histories have been delineated and reviewed. treatment is highly individualized. amputation is still recommended for grotesque deformities of the upper limb. early aggressive surgery, when indicated, will improve contour, function, and appearance. specific therapeutic techniques include radical debulking, ...200919380062
pseudomonas aeruginosa las quorum sensing autoinducer suppresses growth and biofilm production in legionella species.bacteria commonly communicate with each other by a cell-to-cell signalling mechanism known as quorum sensing (qs). recent studies have shown that the las qs autoinducer n-(3-oxododecanoyl)-l-homoserine lactone (3-oxo-c(12)-hsl) of pseudomonas aeruginosa performs a variety of functions not only in intraspecies communication, but also in interspecies and interkingdom interactions. in this study, we report the effects of pseudomonas 3-oxo-c(12)-hsl on the growth and suppression of virulence factors ...200919383702
in vitro biological activity screening of lycopodium complanatum l. ssp. chamaecyparissus (a. br.) doll.this article reports the results of selected biological activities, including anticholinesterase, antioxidant, antibacterial, antifungal and antiviral properties, of the petroleum ether, chloroform and methanol extracts as well as the alkaloid fraction of lycopodium complanatum l. ssp. chamaecyparissus (a. br.) doll (lcc, lycopodiaceae) growing in turkey. anticholinesterase effect of the extracts was tested against both acetylcholinesterase (ache) and butyrylcholinesterase (bche) at concentratio ...200919384728
verdoheme formation in proteus mirabilis catalase.heme oxidative degradation has been extensively investigated in peroxidases but not in catalases. the verdoheme formation, a product of heme oxidation which inactivates the enzyme, was studied in proteus mirabilis catalase.200919394409
cardiac tamponade caused by polymicrobial gram-negative organisms.polymicrobial gram-negative pericarditis is a rare entity. we describe the first case of suppurative pericarditis with citrobacter diversus and proteus mirabilis.200919395299
integration of pharmacokinetic and pharmacodynamic indices of orbifloxacin in beagle dogs after a single intravenous and intramuscular administration.the pharmacokinetics (pk) and pharmacodynamics (pd) of orbifloxacin were studied in beagle dogs after intravenous (i.v.) and intramuscular (i.m.) administration at a dose of 2.5 mg/kg body weight. an absolute bioavailability of 100.1% +/- 4.76%, a terminal half-life of 4.23 +/- 0.2 h and 3.95 +/- 0.15 h after i.v. and i.m. administration, a steady-state volume of distribution of 1.61 +/- 0.13 liters/kg, and clearance of 0.31 +/- 0.03 liters/h/kg were observed. orbifloxacin showed rapid, concentr ...200919398644
quinine is bactericidal.to determine the antibacterial properties of quinine dihydrochloride and its mic.200919402279
[effect of the drug-resistant attenuated bacillus proteus on cd80 and cd86 protein expression in peripheral blood dendritic cells of hepatitis b patients].to explore the effect of the drug-resistant attenuated bacillus proteus on the protein expression of cd80 and cd86 in peripheral blood dendritic cells (dcs) of hepatitis b patients.200919403426
tourniquets and exsanguinators: a potential source of infection in the orthopedic operating theater?fomites are increasingly being recognised as a source of hospital-acquired infection. we have therefore assessed tourniquets and exsanguinators for the presence of bacterial pathogens in 1 elective and 2 trauma orthopedic hospitals.200919404812
management of complicated infections in the era of antimicrobial resistance: the role of tigecycline.increasing antimicrobial resistance and infection complications pose challenges to optimal antibiotic therapy. paucity of new antibiotics (and the eventual bacterial resistance they face) highlights the critical need for more appropriate use of broadly effective agents, which may help to thwart the dramatic rise in global resistance. single agents that can be combined effectively with others, if needed, promise the simplest overall utility. approved in 2005 to treat complicated skin and intra-ab ...200919405794
[etiology of urinary tract infections and antimicrobial susceptibility: a study conducted on a population of children hospitalized in the department of pediatrics at warsaw bielany hospital; 2004-2006].the basis of urinary tract infection (uti) diagnosis in children is based on positive results of microbiological tests. the selection of an antimicrobial drug for empirical treatment and prophylaxis of uti is determined by the susceptibility of bacterial strains isolated from urine cultures.200819418948
comparison of clinical symptoms scored according to the national institutes of health chronic prostatitis symptoms index and assessment of antimicrobial treatment in patients with chronic prostatitis syndrome.we examined a total of 194 patients over 18 years of age with chronic prostatitis syndrome and no evidence of structural or functional lower genitourinary tract abnormalities. the following data were obtained for each patient: clinical history--the severity of chronic prostatitis symptoms scored by a croatian translation of the nih cpsi questionnaire, clinical status including digitorectal examination, urethral swab specimens, and selective samples of urine and expressed prostatic secretion, acc ...200919423471
bacterial toxin higb associates with ribosomes and mediates translation-dependent mrna cleavage at a-rich sites.most pathogenic proteus species are primarily associated with urinary tract infections, especially in persons with indwelling catheters or functional/anatomic abnormalities of the urinary tract. urinary tract infections caused by proteus vulgaris typically form biofilms and are resistant to commonly used antibiotics. the rts1 conjugative plasmid from a clinical isolate of p. vulgaris carries over 300 predicted open reading frames, including antibiotic resistance genes. the maintenance of the rts ...200919423702
effects of proteus vulgaris growth on the establishment of a cheese microbial community and on the production of volatile aroma compounds in a model cheese.to investigate the impact of proteus vulgaris growth on a multispecies ecosystem and on volatile aroma compound production during cheese ripening.200919426267
correlation between antibiotic consumption and bacterial resistance as quality indicator of proper use of these drugs in inpatients.antibiotics are the most frequently used medications in serbian hospitalized patients. information about antibiotic utilization and sensitivity among inpatients in serbia is scanty, and there are no available publications on the topic. the aim of this study was to investigate the correlation between antibiotic use and bacterial resistance in the clinical center nis, one of the biggest hospitals in serbia.200919432297
antibacterial profile of fermented seed extracts of ricinus communis: findings from a preliminary analysis.the study was carried out to ascertain the antibacterial properties inherent in fermented seed extracts of ricinus communis. dry seeds of r. communis (castor oil plant) were deshelled, grounded to powder, fermented, and then extracted both with alcohol and water using soxhlet machine. different concentrations of the extracts were tested against selected bacteria using diffusion method of susceptibility testing on sensitivity testing agar medium. klebsiella pneumoniae, escherichia coli, proteus v ...200819434215
[preliminary data on the utilization of monural to treat pregnant women with asymptomatic bacteriuria]. 200819452625
detection of ampc beta-lactamases in escherichia coli, klebsiella spp., salmonella spp. and proteus mirabilis in a regional clinical microbiology laboratory.there are currently no standardized diagnostic tests available for the reliable detection of ampc beta-lactamases in klebsiella spp., escherichia coli, proteus mirabilis and salmonella spp. a study was designed to evaluate a confirmation disk test using cefotetan (ctt) and cefoxitin (fox) with phenylboronic acid (pba). it also investigated the most suitable screening concentrations of fox, ceftriaxone (cro) and ceftazidime (caz) for the detection of ampc beta-lactamases. a total of 126 control ( ...201019456838
[ability of opportunistic enterobacteria to adapt to different temperatures].to study variability of enzymatic apparatus of opportunistic enterobacteria.200919459471
antimicrobial activity of selected plant species from "the argentine puna" against sensitive and multi-resistant bacteria.the plant species reported here are traditionally used in the "puna" or "altiplano" of argentina for ailments related to bacterial infections. the aim of this study was to evaluate their antimicrobial properties against a panel of sensitive and multi-resistant gram-positive and gram-negative bacteria.200919467313
the effect of edta instillations on the rate of development of encrustation and biofilms in foley catheters.the aim of this research was to examine whether a daily instillation of tetra sodium ethylenediaminetetraacetic acid (edta) solution could reduce the rate at which encrustation by crystalline proteus mirabilis biofilms blocks urinary catheters. sets of three bladder models were fitted with size 14 all-silicone catheters. tetra sodium edta solution was instilled into the catheter following biofilm development. catheters were examined by digital photography and scanning electron microscopy for evi ...200919468723
[epidemiology of bacterial intrahospital infections in newborns].nosocomial infections are important problem for the modern medicine. especially sensitive category, susceptible to nosocomial infections, are the infants. the aim of the research was to establish an active monitoring over the breaking out of the nosocomial infections in the neonatology department of the gynecology and obstetrics clinic of the university clinical center tuzla (ukc) and to determine the kind of bacteria that causes the nosocomial infections as well as the type of infection accordi ...200819469274
chemical compositions and antibacterial activities of the essential oils from aerial parts and corollas of origanum acutidens (hand.-mazz.) ietswaart, an endemic species to turkey.essential oils extracted by hydrodistillation from the aerial parts and corollas of origanum acutidens (hand.-mazz.) ietswaart, an endemic turkish flora species, were analyzed by gc-ms. the amounts of essential oil obtained from the aerial parts and the corollas were 0.73% and 0.93%, respectively. twenty-five components in both the aerial parts oil and the corolla oil, representing 95.11% and 93.88%, respectively, were identified. the aerial parts and corolla oils were characterized by the predo ...200919471191
antibiotic resistance of gram negatives isolates from loggerhead sea turtles (caretta caretta) in the central mediterranean sea.previous studies on fish and marine mammals support the hypothesis that marine species harbor antibiotic resistance and therefore may serve as reservoirs for antibiotic-resistance genetic determinants. the aim of this study was to assess the resistance to antimicrobial agents of gram negative strains isolated from loggerhead sea turtles (carettacaretta). oral and cloacal swabs from 19 live-stranded loggerhead sea turtles, with hooks fixed into the gut, were analyzed. the antimicrobial resistance ...200919473669
incidence of multiple antibiotic resistant gram-negative bacteria isolated from surface and underground water sources in south western region of nigeria.in most rural and urban settlements, particularly in nigeria, wells, spring, streams or rivers and lakes serves as major sources of water supply for drinking and other domestic purposes. unfortunately, many of the available water sources are not potable without some form of treatment which is seldom available in most settings. the use of untreated surface water sources for drinking and for domestic purposes remains a major threat to public health as these could serve as reservoirs the for transf ...200919474486
design and quality control of a pharmaceutical formulation containing natural products with antibacterial, antifungal and antioxidant properties.the aims of the present study were to determine the antibacterial and antifungal activity as well as mutagenicity of sechium edule fluid extract and to obtain a pharmaceutical formulation with them. the extract exhibited antimicrobial activity against escherichia coli, klebsiella pneumoniae, proteus mirabilis, enterobacter cloacae, serratia marcescens, morganella morganii, acinetobacter baumannii, pseudomonas aeruginosa, stenotrophomonas maltophilia, candida spp. and aspergillus spp. isolated fr ...200919477252
rheumatoid arthritis is caused by proteus: the molecular mimicry theory and karl popper.rheumatoid arthritis is a crippling and disabling joint disease affecting over 20 million people. it occurs predominantly in women and smokers, and affects the hla-dr1/4 individuals who carry the "shared epitope" of amino acids eqrraa. the cause of this disease was investigated by the methods of the philosopher of science karl popper who suggested that scientific research should be based on bold conjectures and critical refutations. the "popper sequences" generate new facts which then change or ...200919482674
an appraisal of current management of childhood urinary tract infections among private medical practitioners.private medical practitioners manage substantial number of children with urinary tract infection in nigeria. it is important to evaluate the management of urinary tract infection (uti), because of complications that may arise form improper treatment.200919485147
dependence of swarming in escherichia coli k-12 on spermidine and the spermidine importer.in a previous work, it was observed that the swarming of polyamine-deficient proteus mirabilis (speb::sm) was severely inhibited on luria-bertani (lb) swarming plates (lbsw) (lb, 0.5% glucose, 0.5% agar), and it was clarified that extracellular putrescine was important as a signaling molecule for the induction of swarming in p. mirabilis. however, a polyamine-deficient strain (delta-speab delta-spec) of escherichia coli swarmed as well as the parental strain on lbsw plates. we report that the sw ...200919493013
structural and functional studies of truncated hemolysin a from proteus mirabilis.in this study we analyzed the structure and function of a truncated form of hemolysin a (hpma265) from proteus mirabilis using a series of functional and structural studies. hemolysin a belongs to the two-partner secretion pathway. the two-partner secretion pathway has been identified as the most common protein secretion pathway among gram-negative bacteria. currently, the mechanism of action for the two-partner hemolysin members is not fully understood. in this study, hemolysis experiments reve ...200919494116
oral bacterial flora of the chinese cobra (naja atra) and bamboo pit viper (trimeresurus albolabris) in hong kong sar, china.to determine the oral bacterial flora associated with two common local venomous snakes in hong kong, namely the chinese cobra (naja atra) and the bamboo pit viper (trimeresurus albolabris).200919494373
[thoraco-brachial cystic lymphangioma and proteus syndrome: prenatal diagnosis and mr follow-up]. 200919503050
preparation, physicochemical characterization and biological evaluation of cefodizime metal ion complexes.cefodizime is a broad spectrum cephalosporin belonging to the third generation agents. in this study, attention has been paid to the preparation, physicochemical characterization and biological evaluation of new cu2+, zn2+, fe3+, co2+ and al3+ complexes of cefodizime.200919505365
the aresc study: an international survey on the antimicrobial resistance of pathogens involved in uncomplicated urinary tract infections.the aresc (antimicrobial resistance epidemiological survey on cystitis) study is an international survey to investigate the prevalence and susceptibility of pathogens causing cystitis. female patients (n=4264) aged 18-65 years with symptoms of uncomplicated cystitis were consecutively enrolled in nine european countries as well as brazil during 2003-2006. pathogens were identified and their susceptibility to nine antimicrobials was determined. escherichia coli accounted for 76.7% of isolates. am ...200919505803
are sinus-track cultures reliable for identifying the causative agent in chronic osteomyelitis?the infection of bone that contains bone marrow called osteomyelitis, and is caused by different microorganisms. in this study, we aimed to determine the diagnostic value and accuracy of cultures of material from a sinus track compared with those of cultures of bone specimens that have been controversial.200919513734
[evaluation of effectiveness and tolerance of treatment with azithromycin 1.5% eye drops in bacterial conjunctivitis].azithromycin is a macrolide class antibiotic, recently adapted for topical use in ophthalmology. it is effective against the most frequent pathogens found in bacterial conjunctivitis, gram positive and gram negative bacteria. azithromycin has the specificity to have sustained high tissue levels: after repeated instillation, it has been shown to reach sustained concentrations above the mics of susceptible bacteria for 4 days in tears and for 7 days in conjunctiva.200919517846
prevalence of acquired ampc beta-lactamases in enterobacteriaceae lacking inducible chromosomal ampc genes at a spanish hospital from 1999 to 2007.in 2007, a significant increase in acquired ampc genes in enterobacteriaceae from 0.06% in 1999 to 1.3% was observed. proteus mirabilis showed the highest prevalence (0.95%) and cmy-2 was the most prevalent ampc enzyme (66.7%). other enzymes such as cmy-4, dha-1, acc-1, and three new enzymes called cmy-25, cmy-27 and cmy-40 were detected. seven out of the 117 isolates (6%) also produced an extended-spectrum beta-lactamase. as acquired ampc enzymes are likely to become a serious public health iss ...201019523051
veb-6 extended-spectrum beta-lactamase-producing proteus mirabilis from sultanate of oman. 200919525094
thermotolerance and multidrug resistance in bacteria isolated from equids and their environment.sixty-nine vaginal swabs and 138 rectal swabs collected from 195 equids were analysed for the presence of thermotolerant bacteria, that is, bacteria surviving at 60+/-0.1 degrees c for one hour. thermotolerant escherichia coli, enterobacter species, klebsiella pneumoniae, proteus species and pseudomonas species were isolated from 41, 16, nine, three and three of the 138 rectal swabs, respectively; seven of the e coli and two of the enterobacter species isolates survived pasteurisation at 63.8+/- ...200919525523
synergistic interaction between silver nanoparticles and membrane-permeabilizing antimicrobial peptides.silver nanoparticles, as well as antimicrobial peptides (amps), can be used to fight infectious diseases. since amps are known to permeabilize bacterial membranes and might therefore help silver nanoparticles to access internal target sites, we investigated their combined activities and showed synergistic effects between polymyxin b and silver nanoparticles for gram-negative bacteria.200919528287
antibiotic resistance in children with recurrent or complicated urinary tract infection.urinary tract infection is certainly one of the most common childhood infections. emerging resistance to the antibiotics is not unusual. current hospitalization for children with urinary tract infection is reserved for severe or complicated cases. the aim of the present study was to determine the antibiotic resistance pattern among children with recurrent or complicated urinary tract infection.200919529052
asymptomatic bacteriuria during pregnancy.the present study was aimed to test the association between asymptomatic bacteriuria during pregnancy, among patients in whom antibiotic treatment was recommended, and perinatal outcome. our study was also designed to characterize common bacteria and risk factors associated with asymptomatic bacteriuria during pregnancy.200919530000
proteolytic bacteria in the lower digestive tract of poultry may affect avian influenza virus pathogenicity.proteolytic cleavage of hemagglutinin is required for cell entry by receptor-mediated endocytosis and plays a key role in pathogenicity of the influenza virus. despite several studies describing relationships between bacterial proteases and influenza a viral activation in mammals, very little is known about the role of the normal bacterial flora of birds on hemagglutinin activation. we examined the indigenous intestinal microflora of 100 mixed-sex, 27-d-old ross chickens from a commercial poultr ...200919531708
[microbiological sepsis screening in surgical icu patients with the "lightcycler" septifast test--a pilot study].an adequate approach to surgically induced sepsis needs an early and targeted antibiotic therapy in addition to focus sanitation. the pcr-based lightcycler septifast test can detect 90 % of the sepsis-associated microoganisms (e. g., gram-positive, gram-negative bacteria, fungi) within only a few hours.200919536720
impact of infection on the secretory capacity of the male accessory glands.studies that compare the impact of different infectious entities of the male reproductive tract (mrt) on the male accessory gland function are controversial.200919538765
high prevalence of bla(ctx-m-1)-group extended-spectrum beta-lactamase genes in enterobacteriaceae isolates from emilia-romagna, italy. 200919541784
synthesis, antibacterial and antifungal activities of novel 1,2,4-triazolium derivatives.a series of novel 1,2,4-triazolium derivatives was synthesized starting from commercially available 1h-1,2,4-triazole, 2,4-dichlorobenzyl chloride, or 2,4-difluorobenzyl bromide. their antibacterial and antifungal activities were evaluated against staphylococcus aureus atcc 29213, escherichia coli atcc 25922, bacillus proteus, bacillus subtilis, pseudomonas aeruginosa, candida albicans atcc 76615, and aspergillus fumigatus. all structures of the new compounds were confirmed by nmr, ir, and ms sp ...200919544478
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