| [intraocular penetration of netilmicin]. | the penetration of netilmicin, a semisynthetic aminoglycosid into the primary human aqueous humor was determined. the antibacterial spectrum of netilmicin is adequate to gentamicin. the efficacy also covers gentamicin resistant strains. after intramuscular injection of 5 mg/kg body weight aqueous levels higher than the minimum inhibitory concentration (mic) of staphylococcus aureus, escherichia coli, klebsiella, enterobacter, citrobacter and proteus morganii were obtained. in the therapy of bact ... | 1983 | 6603716 |
| nonspecific induction of beta-lactamase in enterobacter cloacae. | since the introduction of the new beta-lactamase-stable beta-lactam compounds, inducible beta-lactamases have become increasingly important clinically [1]. it has recently been pointed out that most beta-lactam antibiotics appear to be affected by these derepressed enzymes either by hydrolysis or by the nonhydrolytic barrier mechanism [2]. until now, it has generally been assumed that beta-lactamases are induced only by the beta-lactam compounds themselves. we investigated an e cloacae strain th ... | 1983 | 6605393 |
| influence of spontaneous and inducible beta-lactamase production on the antimicrobial activity of recently developed beta-lactam compounds. | the activity of 9 recently developed beta-lactam compounds was evaluated in 185 ampicillin-resistant isolates of enterobacteriaceae. moreover, in all strains, spontaneous and inducible beta-lactamase production was quantified and correlated with the minimal inhibitory concentration (mic) of each compound. in most species, no correlation could be observed between spontaneously produced beta-lactamase and the mics, with the only exceptions of serratia spp. and morganella morganii isolates for meth ... | 1984 | 6610539 |
| infections in compromised hosts: impairment of antibody for opsonization of proteus morganii strain 1510 in tumor-bearing mice. | | 1984 | 6610789 |
| the effect of piperacillin prophylaxis on the colonic microflora in patients undergoing colorectal surgery. | piperacillin was given parenterally in doses of 4 g every 8 h for two days to 20 patients undergoing colorectal surgery. a series of serum and fecal specimens were taken to analyse piperacillin concentrations. tissue samples from the gut wall were taken during surgery. the maximum serum concentrations during surgery were reached 15 min after piperacillin administration. on day 0 the mean half-life was 1.9 h and the mean area under the serum concentration curve was 536.8 mg/l. the piperacillin co ... | 1983 | 6642676 |
| antibacterial activity of aztreonam: a synthetic monobactam. a comparative study with thirteen other antibiotics. | the in vitro activity of aztreoman (sq 26, 776), a new monocyclic beta-lactam antimicrobial agent, was determined against 1720 bacteria, all clinical isolates, and compared with that of thirteen beta-lactam and aminoglycoside antibiotics. aztreonam inhibited 90% of citrobacter diversus, citrobacter freundii, enterobacter agglomerans, e. coli, klebsiella pneumoniae, proteus mirabilis, proteus morganii, proteus rettgeri, proteus vulgaris and salmonella sp. by less than or equal to 0.4 micrograms m ... | 1983 | 6684718 |
| excretion of cefuroxime in biliary disease. | cefuroxime is a broad spectrum b-lactamase stable cephalosporin antibiotic. an intravenous injection of cefuroxime sodium 1.5 grams was administered to 45 patients after induction of anesthesia for cholecystectomy. twenty-five patients had elective operations for chronic cholecystitis and 20 underwent urgent operations for acute cholecystitis. of the 25 patients who underwent elective treatment, the cystic duct was patent in 13 and obstructed in 12. antibiotic concentrations were measured by mic ... | 1984 | 6701741 |
| reliability of early identifications obtained with enterobacteriaceae-plus biochemical cards in the automicrobic system. | the automicrobic system (ams) is capable of identifying most enterobacteriaceae within 8 h and many glucose-nonfermenting, gram-negative bacilli after 13 h of incubation. early preliminary results can be readily obtained from the computer as the tests incubate. data with 1,023 bacterial isolates were reviewed to determine the relative accuracy of 4-, 6-, 8-, 10-, and 13-h identifications. all automicrobic system identifications with probability (p) values of less than 0.80 were considered equivo ... | 1982 | 6749890 |
| comparison of three methods for identification of enterobacteriaceae. | this study compares the ability of three commercial overnight methods, api 20e, minitek and enteric-tek, to accurately and completely identify 368 clinically isolated enterobacteriaceae without supplemental tests. organisms included escherichia coli (54 strains), shigella spp. (7), edwardsiella tarda (1), salmonella enteritidis (10), citrobacter spp. (30), klebsiella spp. (55), enterobacter spp. (68), hafnia alvei (2), serratia spp. (33), proteus spp. (64), morganella morganii (24), providencia ... | 1982 | 6756905 |
| correlation of beta-lactamase production and resistance to beta-lactam antibiotics in enterobacteriaceae. | incidence of beta-lactamase production (using the nitrocefin test and isoelectric focusing) was evaluated on 284 strains of ampicillin-resistant enterobacteriaceae. production of the various beta-lactamases was correlated with the resistance to different beta-lactam antibiotics. no obvious correlation between the beta-lactamase production and the resistance pattern was found. the most striking result was the lack of beta-lactamase production in 42.6% of the strains. about 50% or more of the prot ... | 1982 | 6758422 |
| augmentin: laboratory studies. | clavulanic acid is a beta-lactam antibiotic which, although it has little intrinsic activity, is a potent inhibitor of bacterial beta-lactamases. when combined with amoxycillin its range of activity includes penicillinase-producing strains of staphylococcus aureus and many of the beta-lactamase-producing strains of gram-negative bacilli. bacteria sensitive to augmentin include amoxycillin-resistant strains of haemophilus influenzae and escherichia coli, in addition strains of klebsiella aerogene ... | 1982 | 6762661 |
| in vitro antibacterial activity and susceptibility of cefsulodin, an antipseudomonal cephalosporin, to beta-lactamases. | cefsulodin sodium (sce-129, cgp-7174/e), active in minimum inhibitory concentrations (mics) of 0.5 to 64 microgram/ml, was about 16- to 32-fold more active than carbenicillin against psuedomonas aeruginosa. it was also active against p. diminuta, p. maltophilia, p. paucimobilis, and p. pseudoalcaligenes (mics of 1 to 32 microgram/ml) but not against other species of pseudomonas or other gram-negative bacteria. except with highly carbenicillin-resistant isolates, mics of cefsulodin for p. aerugin ... | 1980 | 6770753 |
| unusual groups of morganella ("proteus") morganii isolated from clinical specimens: lysine-positive and ornithine-negative biogroups. | morganella ("proteus") morganii is the only species in the recently proposed genus morganella, but we suspect there are yet undescribed species in the genus. two candidates for new species were recently investigated. nineteen strains isolated from clinical specimens resembled m. morganii but were lysine positive and nonmotile and fermented glycerol within 24 h. typical m. morganii are lysine negative and motile and ferment glycerol slowly or not at all. the three-test variance from typical m. mo ... | 1980 | 6775010 |
| clonotypes of anti-phosphocholine antibodies induced with proteus morganii (potter). i. structural and idiotypic similarities in a diverse repertoire. | | 1980 | 6776194 |
| phagocytic and chemiluminescent responses of mouse peritoneal macrophages to living and killed salmonella typhimurium and other bacteria. | in the presence of luminol, resident as well as thioglycolate-induced and immunized macrophages emitted chemiluminescence more efficiently when the cells were exposed to living salmonella typhimurium than when they were exposed to the same bacterium killed by ultraviolet light or heat. this phenomenon was observed whether or not the bacterium was opsonized. the different response to living and killed bacteria was also found with escherichia coli, pseudomonas aeruginosa, proteus morganii, and ent ... | 1981 | 6788707 |
| plasmid-encoded lysine decarboxylation in proteus morganii. | as a rule, proteus morganii does not decarboxylate lysine. however, lysine-positive p. morganii strains have been recently described. we suspected a plasmid origin for this atypical character, and we analyzed 14 strains to study this question. among these strains, 8 yielded lysine-negative segregants after acridine orange or ethidium bromide treatment, and 10 transferred their lysine-positive character to a recipient p. morganii strain. all of the 14 strains analyzed at least segregated or conju ... | 1981 | 6793621 |
| bacteriological studies of the enteric flora of patients treated with bicozamycin (cgp 3543/e) for acute nonparasitic diarrhea. | during a therapeutic trial of bicozamycin (bi) for traveler's diarrhea, aerobically grown, gram-negative bacteria, predominantly escherichia coli, were decreased by 2 to 3 logs per g of stool; the number of bi-resistant gram-negative bacteria did not increase. resistant species were most often citrobacter freundii, klebsiella pneumoniae, and morganella morganii, and few bi-resistant e. coli strains were isolated. cross-resistance between bi and other antimicrobial agents was not found. resistanc ... | 1983 | 6859842 |
| mobilization of the proteus morganii chromosome by r plasmids. | r plasmids r702, r711b, r1, d, rip69, r447b, r471 and r394, belonging to different incompatibility groups, mobilized the proteus morganii 2815 chromosome. matings employing plasmids r711b or r702 as sex factors with doubly auxotrophic recipients produced recombinants characterized by the obligatory inheritance of ser-1+, irrespective of the selected marker. | 1980 | 6934261 |
| in vitro-constructed rp4-prime plasmids mediate orientated mobilization of the proteus morganii chromosome. | rp4-prime plasmids containing inserts of proteus morganii strain 2815 chromosomal dna (0.5-13 megadaltons in size) were constructed in vitro. when introduced into the latter organism, the hybrid plasmids promoted transfer of chromosomal markers in an orientated manner, with recombinant frequencies from 10(-4) to 10(-6) per donor. transconjugants expressed the tetracycline-resistant phenotype of the plasmids. plasmid-guided trajectories overlapped and a circular map of chromosome markers was cons ... | 1982 | 6956673 |
| properties of cephalosporinase from proteus morganii. | the cephalosporin beta-lactamase (cephalosporinase) was purified from a strain of proteus morganii which showed resistance to cephalosporins. the optimal ph was about 8.5, and the optimal temperature was 40 degrees c. the isoelectric point was 8.7 and the molecular weight was estimated to be about 41,000 from sodium dodecyl sulfate-acrylamide gel electrophoresis. the enzyme activity was inhibited by cloxacillin, ampicillin, carbenicillin, cefuroxime, cefotaxime, ceftizoxime (fk749), cefmenoxime ... | 1981 | 6976340 |
| experimental infections for the evaluation of beta-lactamase resistance. | the antibacterial activity and pharmacokinetics of the beta-lactamase-stable cephalosporin cefuroxime and the gram-negative beta-lactamase-susceptible cephalosporin cefazolin were compared in two contrasting infection models in which proteus morganii 82, which produces chromosomally mediated beta-lactamase, was the pathogen. in the rat paw model, characterized by high numbers of localized bacteria, cefazolin was destroyed at the site of infection and consequently did not produce a therapeutic re ... | 1982 | 6978673 |
| potent cephalosporinase inhibitors: 7 beta-[2-(1, 3-dithiolan-2-ylidene) acetamido] cephalosporins and related compounds. | cephalosporins possessing a 1, 3-dithiolane, 1, 3-dithiane, or 1, 3-dithietane ring on their 7 beta-substituents showed potent inhibitory activity against cephaloridine hydrolysis by cephalosporinases purified from proteus morganii, proteus rettgeri, and proteus inconstans, which were not inhibited by clavulanic acid, a well-known beta-lactamase inhibitor. the mode of inhibition was competitive. the dithiolane cephalosporins themselves were stable against hydrolysis by the beta-lactamases tested ... | 1982 | 6979310 |
| screening of bacterial isolates for mannose-specific lectin activity by agglutination of yeasts. | a total of 393 clinical bacterial isolates were tested for their ability to agglutinate yeast cells of either saccharomyces cerevisiae or candida albicans. a positive agglutination of yeasts that could be prevented by methyl alpha-d-mannoside was taken as an indication for the possible presence of a mannose-specific lectin (carbohydrate-binding protein) on the surface of the tested bacteria. agglutination tests on glass slides showed that 38% of all the isolates tested were positive in their cap ... | 1980 | 6989854 |
| the effect of acetohydroxamic acid on the induction of bacterial ureases. | the ureases of proteus mirabilis, proteus vulgaris, and proteus rettgeri are inducible by urea. induction is increased when both urea and acetohydroxamic acid, an inhibitor of urease, are present during bacterial growth. acetohydroxamic acid alone does not cause induction, but, by preventing the hydrolysis of urea, it minimizes ph increases and allows induction to occur much more effectively. the ureases of proteus morganii and other bacterial genera are not inducible by this method. the relevan ... | 1980 | 6997229 |
| evaluation of the four-hour micro-id technique for direct identification of oxidase-negative, gram-negative rods from blood cultures. | a 4-h micro-id technique for direct identification of oxidase-negative gram-negative rods from positive blood cultures was compared to subculture and species identification of single colonies by api 20e and micro-id, using standardized inocula. a total of 127 patients (220 positive cultures) were studied. isolates included 96 escherichia coli, 46 klebsiella pneumoniae, 7 klebsiella oxytoca, 8 enterobacter aerogenes, 17 enterobacter cloacae, 19 serratia marcescens, 2 serratia liquefaciens, 8 prot ... | 1980 | 6999020 |
| cefoxitin resistance by a chromosomal cephalosporinase in escherichia coli. | cefoxitin resistance, an unique property found in clinical isolates of escherichia coli was investigated. cefoxitin resistant strains, 255 and gn206, produced cephalosporinase constitutively. the cephalosporinase was located in the periplasm, and its production was considered to be mediated by chromosomal gene(s). cephalosporinase-less mutants from both strains were susceptible to cefoxitin as well as other beta-lactam antibiotics, suggesting that the cephalosporinase was responsible for the res ... | 1980 | 7002896 |
| alpha-haemolysin: an additive virulence factor in escherichia coli. | haemolytic escherichia coli, including human intestinal and extraintestinal as well as porcine enterotoxigenic and oedema disease isolates, and proteus morganii strains were studied for their virulence. hly+ wild type strains and hly+ transconjugants were more virulent than hly- derivatives as shown in mice and chick embryos. this enhanced virulence seems to be connected with the ability of diffusible alpha-haemolysin production because clones producing only non-diffusible, beta-haemolysin behav ... | 1980 | 7008511 |
| role of urease in the formation of infection stones: comparison of ureases from different sources. | bacterial and vegetable ureases were found to differ in certain important respects. for maximal clinical relevance, in vitro studies on the pathogenic role of urease should use whole bacterial cells of proteus spp., and urease inhibitors should be assessed without preincubation of enzyme with inhibitor. urease from proteus morganii was very different from ureases of other species of proteus; this factor should be taken into account when infections with p. morganii are being treated. | 1981 | 7012032 |
| differential plating medium for quantitative detection of histamine-producing bacteria. | a histidine-containing agar medium has been devised for quantitative detection of histamine-producing bacteria that are alleged to be associated with scombroid fish poisoning outbreaks. the responsible bacteria produce a marked ph change in the agar, with attendant color change of ph indicator adjacent to the colonies, thus facilitating their recognition. proteus morganii and klebsiella pneumoniae were the two most common histidine-decarboxylating species isolated from scombroid fish and mahi ma ... | 1981 | 7013698 |
| proteus-typing by proticin production and susceptibility. | a proteus-typing method based on proticin production and proticin susceptibility (c.f. senior, 1977) has been modified to increase its sensitivity proticins were prepared in fluid medium and applied to agar-plates shortly before seeding the plates with indicator bacteria. a given 10 proticin producer strains, which are responsible for the susceptibility patterns of the indicator-bacteria (s-types), form the foundation for this typing method. using this producer-set and indicator-set (28 strains) ... | 1981 | 7039501 |
| comparison of micro-id and api 20e in rapid identification of enterobacteriaceae. | the effectiveness of micro-id and api 20e as same-day identification systems for enterobacteriaceae was evaluated in comparison with conventional identification by using 315 clinical isolates and 90 stock strains. the api 20e system was heavily inoculated according to manufacturer's recommendations for same-day identification. we found that 83 and 81% of isolates provided adequate inocula for micro-id and api 20e, respectively, and purity of the heavy inocula was not a problem with either system ... | 1982 | 7047556 |
| penem derivatives: beta-lactamase stability and affinity for penicillin-binding proteins in escherichia coli. | penem derivatives, a new group of beta-lactam antibiotics with potent activities against a wide range of bacteria, including pseudomonas aeruginosa, were tested for their stability against hydrolysis by beta-lactamases purified from clinical isolates of morganella morganii. proteus vulgaris, and escherichia coli and by a penicillinase from bacillus cereus. penems having 6 alpha substituents, such as hydroxyethyl, hydroxymethyl, and ethyl groups, were very stable against hydrolysis by each of the ... | 1982 | 7049076 |
| comparison of two methods for same-day identification of enterobacteriaceae. | two commercial methods, api 20e (as modified for same-day enterobacterial identification) and micro-id, were evaluated for ability to provide useful same-day information of 368 clinically isolated enterobacteriaceae. organisms included escherichia coli (54), shigella (7), edwardsiella tarda (1), salmonella enteritidis (10), citrobacter (30), klebsiella (55), enterobacter (68), hafnia alvei (2), serratia (33), proteus (64), morganella morganii (24), providencia (18), and yersinia enterocolitica ( ... | 1982 | 7051807 |
| clonotypes of anti-phosphocholine antibodies induced with proteus morganii (potter). ii. heterogeneity, class, and idiotypic analyses of the repertoires in balb/c and a/hej mice. | the heterogeneity of the pc-specific igg response of proteus morganii (potter) was systematically analyzed. serum samples from individual mice were focused in paired adjacent tracks, pc-specific antibodies were detected with 125i-pc-rnase, and the resulting autoradiographs were examined for co-focusing bands. both the number of different antibody band groups and their frequency of expression were determined. varying qualitatively from simple to complex, the spectrotypes of 38 balb/c and 19 a/hej ... | 1982 | 7054290 |
| hand carriage of aerobic gram-negative rods by health care personnel. | a quantitative culture technique (hand washed in a glove containing broth for 30 s) was used to determine the frequency of hand carriage of aerobic gram-negative rods by various groups of health care workers and 104 control subjects. overall, 31% of health care workers carried aerobic gram-negative rods on their hands compared to 59% of control subjects (p < 0.001). enterobacter agglomerans accounted for 40% of the isolates, and other enterobacter spp. 7%. other organisms included acinetobacter ... | 1982 | 7097001 |
| infections in compromised hosts: modified susceptibility of tumor-bearing mice to experimental infection with proteus morganii strain 1510. | | 1982 | 7161991 |
| [histamine formation by proteus species in tunafish (author's transl)]. | introducing the authors report on cases of scombroid poisoning episodes in food serving establishments. these cases were related to the formation of histamine in tuna meat due to proteus morganii although the meat was sound when taken from cans. it is demonstrated experimentally (table 1) and shown in a critical literature review (table 2) that among proteus species proteus morganii is the only species being able of producing histamine levels high enough to cause food poisoning in humans. multip ... | 1981 | 7198852 |
| a comparison of the in vitro activity of cefoxitin and cephalothin against 7,312 clinical isolates. | the antibacterial activity of cefoxitin and cephalothin was tested against 7,312 clinical isolates of aerobic pathogens. cefoxitin was found to have a broad spectrum of activity. among the gram-positive cocci, 99.1% of staphylococcus aureus, 94.4% of staphylococcus epidermidis and 98.1% of streptococci group b had a minimal inhibitory concentration of 16 microgram/ml or less, while only 4.6% of enterococci were sensitive to this concentration of cefoxitin. among the gram-negative rods 94.4% of e ... | 1981 | 7249786 |
| hospital cluster epidemic with morganella morganii. | a cluster epidemic of 13 morganella morganii infections involving 11 patients occurred over a 3-month period in 1977. this epidemic was unusual in that it involved four services and five hospital floors. the outbreak was effectively terminated when strict asceptic techniques were reinforced. | 1981 | 7309851 |
| in vitro and in vivo antibacterial activity of ab206, a new naphthyridine derivative. | ab206 (5,8-dihydro-5-methoxy-8-oxo-2h-1,3-dioxolo-4,5-g quinoline 7-carboxylic acid) is a novel antibacterial agent structurally related to nalidixic acid. ab206 has potent antibacterial activity against clinical isolates of gram-negative bacteria and is 4 to 18 times more active than nalidixic acid. ab206 inhibited the growth of staphylococcus aureus and pseudomonas aeruginosa, which were resistnat to nalidixic acid. cross-resistance was not observed between ab206 and various antibiotics, and m ... | 1980 | 7387143 |
| aerobic and anaerobic bacteriology of perirectal abscess in children. | aspirates of pus from perirectal abscesses in 28 children were studied for aerobic and anaerobic bacteria. a total of 87 isolates (64 anaerobic and 23 aerobic) were recovered from the patients, an average of 2.3 anaerobes and 0.8 aerobes per specimen. anaerobic organisms alone were recovered from 15 specimens (54%), and in nine specimens (32%) they were mixed with aerobic organisms. aerobic organisms were recovered in pure culture in only four patients (14%). the predominant anaerobic organisms ... | 1980 | 7402814 |
| bacterial agents causing chronic suppurative otitis media. | ear swabs from 350 patients with chronic otitis media attending different orthorhinolaryngological clinics at different hospitals and health centres in benin city and ekpoma in edo state were screened for the presence of bacterial agents of chronic otitis media. results revealed the presence of 19 different species indicating polymicrobial infections. species isolated comprised staphylococcus aureus (33.6%), pseudomonas aeruginosa (19.3%), proteus mirabilis (17%), alcaligenes faecalis (6.2%) and ... | 1995 | 7498006 |
| pore formation in artificial membranes by the secreted hemolysins of proteus vulgaris and morganella morganii. | lipid-bilayer experiments were performed with the related hemolysins from proteus vulgaris and morganella morganii (hlya). the addition of the toxins to the aqueous phase bathing lipid-bilayer membranes composed of different lipids resulted in the formation of transient ion-permeable channels. membranes formed of pure lipids were rather inactive targets for the hemolysins as compared with lipid mixtures such as asolectin. the channels had several different substrates. the major open state had si ... | 1994 | 7510229 |
| initiation of the phosphocholine-specific response to proteus morganii. b cell transfectants expressing unmutated vh/vl can respond to stimulation by p. morganii antigen. | we wished to resolve a paradox of how the response to the phosphocholine (pc) determinant of proteus morganii could be initiated from a precursor b cell whose receptor, in unmutated form as ab, appears to be unable to bind ag. unmutated vh and unmutated vl constructs were co-transfected into the b cell lymphoma m12.4 to study stimulation via membrane lg (mlg). the same vh construct was expressed in an l+, h- hybridoma line to characterize ab binding. the unmutated ab showed no detectable binding ... | 1995 | 7544373 |
| commensal enteric bacteria engender a self-limiting humoral mucosal immune response while permanently colonizing the gut. | we have employed a germfree mouse model to study the development and persistence of a humoral mucosal immune response to a gram-negative murine commensal organism, morganella morganii. m. morganii bacteria rapidly colonize the gut, resulting in hypertrophy of peyer's patches (pp), including germinal center reactions (gcr), and the development of specific immunoglobulin a (iga) responses detected in vitro in pp fragment cultures and by elispot assays of lamina propria cells. the gcr peaks 14 days ... | 1995 | 7558298 |
| the in-vitro activity of cp 99,219, a new naphthyridone antimicrobial agent: a comparison with fluoroquinolone agents. | the in-vitro activity of a new fluoroquinolone, cp 99,219 was compared with that of ciprofloxacin, du 6859, sparfloxacin and levofloxacin. cp 99,219 showed generally similar in-vitro activity to the other compounds tested against the enterobacteriaceae (mic90 of all agents < 0.5 mg/l except morganella morganii). it was found to be more active than ciprofloxacin, sparfloxacin and levofloxacin against the strains of acinetobacter calcoaceticus tested (mic90 1 mg/l). cp 99,219 was found to be four- ... | 1995 | 7559198 |
| [in vitro activity of six beta-lactams against 295 strains of enterobacteriaceae and p. aeruginosa isolated from neutropenic patients]. | the in vitro activity of two new beta-lactam agents, cefpirome (cpo) and cefepime (fep), was investigated against 295 gram-negative bacilli (250 enterobacteriaceae and 45 p. aeruginosa) isolated from neutropenic patients. they were compared with ceftazidime (caz), piperacillin-tazobactam (tzp), imipenem (ipm) and cefotaxime (ctx). all enterobacteriacae were susceptible to ipm, 16 strains were intermediately susceptible or resistant to caz (1 strain of e. coli, 4 of morganella morganii and 11 of ... | 1995 | 7567110 |
| ceftibuten: a review of antimicrobial activity, spectrum and other microbiologic features. | ceftibuten is a new, orally administered cephalosporin with exceptional beta-lactamase stability and potency against commonly isolated gram-negative pathogens. more than 90% of recent enterobacteriaceae clinical isolates were inhibited by < or = 8 micrograms/ml of ceftibuten. in only five enteric species (citrobacter freundii, enterobacter aerogenes, enterobacter cloacae, morganella morganii, serratia marcescens) were more than 15% of strains resistant (minimal inhibitory concentrations (mic, wi ... | 1995 | 7567314 |
| toc-39, a novel parenteral broad-spectrum cephalosporin with excellent activity against methicillin-resistant staphylococcus aureus. | toc-39, a new parenteral cephalosporin, is a hydroxyimino-type cephem antibiotic with vinylthio-pyridyl moiety at the 3 position. toc-39 was evaluated for antibacterial activity against various clinically isolated strains. toc-39 had excellent activity, stronger than that of methicillin, oxacillin, the cephalosporins tested, imipenem, gentamicin, minocycline, tobramycin, ofloxacin, and ciprofloxacin against methicillin-resistant staphylococcus aureus (mrsa) and had an mic comparable to that of v ... | 1995 | 7625799 |
| comparative antibacterial activity of l-695,256, a carbapenem active against methicillin-resistant staphylococci. | the activity of a new prototype carbapenem, l-695,256, against clinical isolates of gram-positive and gram-negative aerobes was studied in vitro by agar dilution. l-695,256 was highly active against methicillin-resistant and -susceptible isolates of staphylococci (mics, 0.016 to 2 micrograms/ml) and against penicillin-resistant pneumococci (mics, 0.016 to 0.064 micrograms/ml), irrespective of penicillin susceptibility. activity against members of the family enterobacteriaceae was less than that ... | 1995 | 7625810 |
| junctional diversification in the generation of the precursor of a discrete immune response. | phosphocholine (pc)-specific antibodies that arise in the mouse in response to proteus morganii (pm) and use v1-dfl16.1-jh1 are characterized by a number of recurring mutations. most striking is an invariant a for g substitution in codon 95 of vh which results in an asparagine instead of aspartate at that position. because of the apparent importance of this substitution in an anti-pc(pm) response, we wanted to determine the molecular basis for this base change. a cdna library derived from pre-im ... | 1993 | 7681150 |
| [comparison of mics of new quinolones obtained using agar-dilution and broth-microdilution procedures]. | minimum inhibitory concentrations (mic) of new quinolones against both gram-positive and gram-negative bacteria obtained using agar-dilution and broth-microdilution procedures were compared. a primary regression curve and a correlation coefficient (r) between 2 mics for each of ofloxacin, ciprofloxacin, tosufloxacin, sparfloxacin or balofloxacin were calculated. for the 5 quinolones, average correlation coefficients were 0.891 for the gram-positive bacteria tested, and 0.865 for the gram-negativ ... | 1995 | 7752452 |
| a histidine decarboxylase gene encoded by the vibrio anguillarum plasmid pjm1 is essential for virulence: histamine is a precursor in the biosynthesis of anguibactin. | we have identified and sequenced an hdc gene in the vibrio anguillarum plasmid pjm1 which encodes a histidine decarboxylase enzyme and is an essential component for the biosynthesis of anguibactin. the open reading frame corresponds to a protein of 386 amino acids with a calculated molecular mass of 44,259.69 da. the amino acid sequence has extensive homology with the pyridoxal-p-dependent histidine decarboxylases of morganella morganii, klebsiella planticola, and enterobacter aerogenes. tn3-hoh ... | 1995 | 7752899 |
| purification and properties of crystalline 3-methylaspartase from two facultative anaerobes, citrobacter sp. strain yg-0504 and morganella morganii strain yg-0601. | 3-methylaspartase (3-methylaspartate ammonia-lyase, ec 4.3.1.2) from two facultative anaerobes from soil, citrobacter sp. strain yg-0504 and morganella morganii strain yg-0601, were purified and crystallized from their crude extracts. both of the citrobacter and morganella enzymes appeared to be a dimer of subunits of m(r) 40,000 and 44,000, respectively. the enzymes had similar enzymological properties: optimum ph for the deamination reaction of (2s,3s)-3-methylaspartic acid, substrate specific ... | 1995 | 7765982 |
| in vitro antibacterial activity and beta-lactamase stability of sy5555, a new oral penem antibiotic. | the antibacterial activity of sy5555, a new oral penem antibiotic, was compared with those of cefaclor, cefixime, and cefteram. sy5555 was more active than the comparison agents against methicillin-susceptible staphylococcus aureus, staphylococcus epidermidis, streptococcus pneumoniae, enterococcus faecalis, citrobacter freundii, enterobacter cloacae, morganella morganii, acinetobacter calcoaceticus, clostridium spp., and bacteroides fragilis. against providencia spp., proteus spp., and haemophi ... | 1994 | 7811005 |
| isolation of three hexahydro-1,3,5-trinitro-1,3,5-triazine-degrading species of the family enterobacteriaceae from nitramine explosive-contaminated soil. | three species of the family enterobacteriaceae that biochemically reduced hexahydro-1,3,5-trinitro-1,3,5-triazine (rdx) and octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (hmx) were isolated from nitramine explosive-contaminated soil. two isolates, identified as morganella morganii and providencia rettgeri, completely transformed both rdx and the nitroso-rdx reduction intermediates. the third isolate, identified as citrobacter freundii, partially transformed rdx and generated high concentratio ... | 1994 | 7811097 |
| in vitro antimicrobial activity of cefpirome against ceftazidime-resistant isolates from two multicenter studies. | the in vitro activity of cefpirome against ceftazidime-resistant (mic > 16 mg/l) isolates from two multicenter studies was analyzed. the first investigation carried out in the usa, was an in vitro comparison of cefpirome and five third-generation cephalosporins in which more than 6,000 isolates were evaluated, including 97 enterobacteriaceae and 1,509 staphylococci resistant to ceftazidime. the second study was a multicenter international study (> 5,000 strains total) in which 160 ceftazidime-re ... | 1994 | 7813503 |
| in vitro activity of subinhibitory concentrations of quinolones on urea-splitting bacteria: effect on urease activity and on cell surface hydrophobicity. | the effect of subinhibitory concentrations of ciprofloxacin, lomefloxacin, norfloxacin, ofloxacin, and sparfloxacin on urease activity and on cell surface hydrophobicity of urea-splitting bacteria was examined. quinolones at 0.5 mics demonstrated variable effects on bacterial-urease activity. norfloxacin inhibited enzyme activity in proteus vulgaris and proteus mirabilis, while other quinolones had no effects. in morganella morganii, sparfloxacin and ciprofloxacin enhanced urease activity, parti ... | 1995 | 7844396 |
| in vitro activity of cp-99,219, a novel 7-(3-azabicyclo[3.1.0]hexyl) naphthyridone antimicrobial. | the in vitro activity of cp-99,219 was compared with that of ciprofloxacin and sparfloxacin against 814 clinical bacterial isolates using a microdilution method with brain-heart infusion broth. cp-99,219 was the most potent agent tested against methicillin-resistant, ciprofloxacin-susceptible staphylocci (minimum inhibitory concentration [mic]90 < or = 0.25 microgram/ml). cp-99,219 was 32-fold and fourfold more potent than ciprofloxacin and sparfloxacin, respectively, against streptococcus pneum ... | 1994 | 7851087 |
| [clinical study of a new injectable cephem, fk037, for acute bacterial prostatitis]. | fk037, a new injectable cephem antibiotic, was administered in the treatment of 13 acute bacterial prostatitis (mean age 53.5, range 30-79), and its effectiveness and safety were evaluated. the human prostatic fluid (pf) concentration of fk037 on 7 specimens 1 hour after 1 g i.v.d., was in the range of 0.87-7.47 micrograms/ml (mean +/- sd, 3.43 +/- 2.23 micrograms/ml), whereas, the serum concentration averaged 45.3 +/- 2.88 micrograms/ml, the ratio of pf/serum consequently being 0.08 +/- 0.05. i ... | 1994 | 7863869 |
| comparative in vitro activity of fk-037, a new cephalosporin antibiotic. | the in vitro activity of fk-037, a novel parenteral oxime-type cephalosporin, was compared with that of cefepime, cefpirome, ceftazidime, imipenem, and gentamicin against a total of 668 recent clinical isolates. minimum inhibitory concentrations were determined by a standard agar dilution procedure, and all isolates were tested at two inocula (10(4) and 10(6) colony forming units). fk-037 inhibited 90% of isolates of escherichia coli, klebsiella species, proteus mirabilis, p. vulgaris, morganell ... | 1994 | 7867295 |
| variability of peptidoglycan structural parameters in gram-negative bacteria. | muropeptide composition of peptidoglycan from the gram-negative bacteria aeromonas sp., acinetobacter acetoaceticus, agrobacterium tumefaciens, enterobacter cloacae, proteus morganii, pseudomonas aeruginosa, pseudomonas putida, vibrio parahaemolyticus yersinia enterocolitica and escherichia coli, was analyzed by hplc. in all instances peptidoglycan was built up from the same subunits. a wide disparity in the relative abundance of muropeptides and all structural parameters was observed. the contr ... | 1995 | 7867925 |
| morganella morganii meningitis in a patient with aids. | | 1994 | 7884233 |
| cloning and characterization of the napa acid phosphatase/phosphotransferase of morganella morganii: identification of a new family of bacterial acid-phosphatase-encoding genes. | the gene encoding a minor phosphate-irrepressible acid phosphatase (named napa) of morganella morganii was cloned and sequenced, and its product characterized. napa is a secreted acid phosphatase composed of four 27 kda polypeptide subunits. the enzyme is active on several organic phosphate monoesters but not on diesters, and is also endowed with transphosphorylating activity from organic phosphoric acid esters to nucleosides and other compounds with free hydroxyl groups. its activity is inhibit ... | 1995 | 7894706 |
| in vitro antimicrobial activity of fluoroquinolones against clinical isolates obtained in 1989 and 1990. | the in vitro activity of nine fluoroquinolones, enoxacin, norfloxacin, ofloxacin, ciprofloxacin, lomefloxacin, tosufloxacin, sparfloxacin, fleroxacin and levofloxacin, and two earlier quinolones, nalidixic acid and pipemidic acid, against 1,346 bacterial strains isolated clinically between 1989 and 1990, was evaluated by agar dilution method. the bacteria studied were staphylococcus aureus (including methicillin-susceptible and -resistant strains), staphylococcus epidermidis, enterococcus specie ... | 1993 | 7911351 |
| evaluation of different antimicrobial agents used as selective supplements for isolation and recovery of yersinia enterocolitica. | seventeen antimicrobial agents were evaluated separately or in combination for their efficiency as selective supplements in a broth medium against six different serotypes of yersinia enterocolitica and 20 selected strains of different gram-negative bacteria. irgasan (dp300, 5-chloro-2-(2,4- dichlorophenoxy) phenol) at a concentration of 4 micrograms ml-1 inhibited the growth of most gram-negative bacteria with the exceptions of aeromonas hydrophila, morganella morganii, pseudomonas aeruginosa an ... | 1994 | 7928783 |
| [antibacterial activities of isepamicin against fresh clinical isolates of gram-negative bacilli]. | to investigate antibacterial activities of isepamicin (isp), mics of isp as well as other aminoglycosides (ags) were determined against many strains of gram-negative bacilli that were clinically isolated in 1993. 1. no isp-resistant strains were observed among isolates of escherichia coli, citrobacter diversus, klebsiella spp., enterobacter spp. or proteus mirabilis. 2. isp-resistant strains were observed among isolates of citrobacter freundii, serratia spp., proteus vulgaris, morganella morgani ... | 1994 | 7933534 |
| [multicenter evaluation of oral antibiotics: resistance behavior in 5 swiss centers]. | the susceptibility of 2196 fresh clinical isolates to twelve different oral compounds was assessed in five swiss microbiology institutions during summer 1992. a standardized microdilution system including all other material necessary was employed to assess the antibacterial activity of penicillin g, ampicillin, ampicillin + sulbactam, amoxycillin + clavulanic acid, cefadroxil, cephalexin, cefaclor, cefuroxime, cefetamet, doxycycline, erythromycin and clindamycin. the aminopenicillins (including ... | 1994 | 7939052 |
| microbiological studies of abscesses complicating bothrops snakebite in humans: a prospective study. | forty patients with abscesses at the site of bothrops bite were evaluated. ten brought the snake responsible for the bite, bothrops jararaca in all cases. on admission a sample was collected from each case for aerobic and anaerobic culture, and no abscesses drained spontaneously. none of the patients had received antibacterial therapy at this time. the bacteria most frequently isolated were morganella morganii (23 patients), providencia rettgeri (7) enterobacter sp. (4), escherichia coli (3), gr ... | 1994 | 7940580 |
| in vitro activity of cefpirome against beta-lactamase-inducible and stably derepressed enterobacteriaceae. | most members of the enterobacteriaceae and pseudomonas aeruginosa possess an inducible chromosomal class i beta-lactamase. bacterial strains which produce high levels of beta-lactamase constitutively can be isolated from infections; these derepressed mutants are responsible for resistance to third-generation cephalosporins and ureidopenicillins. minimum inhibitory concentrations of cefpirome, a fourth-generation cephalosporin, and other beta-lactam antibiotics were determined for a series of mut ... | 1994 | 7956454 |
| comparative in-vitro activity of biapenem against enterobacteria with beta-lactamase-mediated antibiotic resistance. | the effects of enterobacterial beta-lactamases were studied for biapenem (l627), a new carbapenem. susceptibility tests were performed for isogenic mutant series of citrobacter freundii, enterobacter cloacae, morganella morganii, serratia marcescens and proteus vulgaris which varied only in chromosomal beta-lactamase expression. beta-lactamase-derepressed organisms in these series were as susceptible as beta-lactamase-inducible strains to biapenem; beta-lactamase-basal mutants were up to eight-f ... | 1994 | 8040111 |
| [antibacterial activity of aztreonam against clinical isolates]. | to evaluate the antibacterial activity of a monobactam antibiotic, aztreonam (azt), mics of azt and other antibiotics against clinical isolates collected at 36 participating institutions after january 1992 were determined using the agar plate dilution method (size of inoculum, 10(6) cfu/ml) according to the japan society of chemotherapy standard. the antibiotics that were tested along with azt included piperacillin (pipc), cefoperazone (cpz), and amikacin (amk). azt was found to be more active a ... | 1994 | 8051793 |
| characterization and sequence of phoc, the principal phosphate-irrepressible acid phosphatase of morganella morganii. | phosphatase activities were investigated in morganella morganii, which is one of the few enterobacterial species producing high-level phosphate-irrepressible acid phosphatase activity (hpap phenotype), and the gene encoding the major phosphate-irrepressible acid phosphatase was cloned, sequenced, and its product characterized. using p-nitrophenyl phosphate as substrate, morganella produced a major phosphate-irrepressible acid phosphatase (named phoc) which is associated with the hpap phenotype, ... | 1994 | 8081499 |
| prediction of bacterial susceptibility to cefpodoxime by using the ceftriaxone minimum inhibitory concentration result. | the cross-resistance or cross-susceptibility of cefpodoxime and ceftriaxone for 3700 strains of enterobacteriaceae, oxacillin-susceptible staphylococci, streptococcus spp., haemophilus influenzae, moraxella catarrhalis, and neisseria gonorrhoeae was evaluated. with the exception of tests with enterobacter spp. and morganella morganii, the ceftriaxone minimum inhibitory concentration (mic) result interpretive criteria predicted bacterial susceptibility (or resistance) to cefpodoxime with an accep ... | 1993 | 8112047 |
| spontaneous bacterial empyema and peritonitis caused by morganella morganii. | | 1994 | 8113596 |
| [in vitro antibacterial activity of isoxazolyl++ naphthoquinones. i]. | the in vitro antibacterial activity of 2-hydroxy-n-(3,4-dimethyl-5-isoxazolyl) 1,4 naphthoquinone-4-imine (i) and three of this derivatives against staphylococcus aureus, escherichia coli, pseudomonas aeruginosa, proteus mirabilis y morganella morganii was investigated. from the four naphthoquinone-imine studied, compound i exhibited activity against s. aureus. this effect was observed even in oxygen atmosphere with 5% co2 and in the presence of human albumin. the development of drug-resistant s ... | 1993 | 8140244 |
| penetration of topically applied ciprofloxacin, norfloxacin, and ofloxacin into the aqueous humor. | to determine the intraocular penetration of topically applied fluoroquinolone antibiotics into aqueous humor. | 1994 | 8190478 |
| [epidermoid cyst of the 4th ventricle. apropos of a case in a child and review of the literature]. | a 6 year-old child was admitted for a recurrent bacterial meningitis at proteus morganii. she was treated with antibiotics. the c.t. scanner showed a midline low-density lesion, with a mild annular contrast uptake in the posterior fossa. m.r.i. showed the lesion and revealed a skin-bone-dura fistula. the surgical resection was complete. it was an epidermoid tumor. intracranial epidermoid tumors constitute about 1% of brain tumors and are considered to be congenital. epidermoid tumors of the 4th ... | 1993 | 8208332 |
| study of enterobacteriaceae throughout the manufacturing and ripening of hard goats' cheese. | the evolution of the counts and the species of enterobacteriaceae as well as some physico-chemical parameters (ph, aw and nacl and moisture contents) during manufacturing and ripening of a hard spanish goats' cheese of the armada-sobado variety were studied. enterobacteriaceae (mean log counts 4.45 g-1 in milk) increased 0.71-2.18 log units in curd and afterwards decreased until they disappeared after 2-4 weeks of ripening. this premature disappearance seems to be due to the decrease in aw value ... | 1993 | 8244902 |
| interpretive accuracy of the disk diffusion method for testing newer orally administered cephalosporins against morganella morganii. | eight newer orally administered cephems (cefdinir, cefetamet, cefixime, cefpodoxime, cefprozil, ceftibuten, cefuroxime, and loracarbef) were tested against 100 clinical strains of morganella morganii to determine the extent of serious interpretive very major (false-susceptible) errors when current criteria for the disk diffusion test are applied. agar dilution mics and disk diffusion tests were performed as recommended by the national committee for clinical laboratory standards (villanova, pa.) ... | 1993 | 8253998 |
| [antimicrobial activity of cefodizime against fresh clinical isolates]. | in order evaluate antimicrobial activities of cefodizime (cdzm), minimum inhibitory concentrations (mic's) of cdzm and other control drugs were determined against various clinical isolates, that were sent to our center from nation-wide medical institutions or were isolated and identified in our laboratory from various specimens of infected patients. the followings are a summary of the results: 1. bacterial species with no or few strains resistant to cephems including cdzm included streptococcus ... | 1993 | 8254888 |
| [the antimicrobial activity of cefteram against recently clinically detected and isolated strains]. | in order to examine antibiotic activities of cefteram (cftm), its minimum inhibitory concentrations (mic's) and those of other cephem drugs were determined against clinically isolated strains received from july 1990 to june 1991 and from july 1992 to february 1993 from medical facilities throughout the country and against clinically isolated strains detected in our laboratory in samples from patients with various infectious diseases. the obtained results are summarized below. 1. no cftm-resistan ... | 1993 | 8254900 |
| [report of three cases of purple urine bag syndrome which occurred with a combination of both e. coli and m. morganii]. | purple urine bag syndrome is a rare phenomenon in which bags turns purple or blue following catheterization. this phenomenon was reported to occur by providencia stuartii in the presence of indicanuria. we reported herein three females above 75 years of age having a similar phenomenon. all were bedridden chronically and constipated. in these cases, no growth of p. stuartii was found on repeated urine culture, but escherichia coli and morganella morganii were concomitantly isolated during the blu ... | 1993 | 8320467 |
| comparative in vitro activity of biapenem, a new carbapenem antibiotic. | biapenem is a new carbapenem antibiotic with high stability to human renal dehydropeptidase i. its in vitro activity was compared with that of imipenem, meropenem, ceftazidime, ceftriaxone, piperacillin and gentamicin against a total of 650 recent clinical isolates. mics were determined by a standard agar dilution procedure and all isolates were tested at two inocula (10(4) and 10(6) cfu). biapenem inhibited 90% of isolates of escherichia coli, klebsiella spp., proteus mirabilis, proteus vulgari ... | 1993 | 8354306 |
| [a nationwide survey of antimicrobial susceptibilities of clinical isolates to antibiotics in japan (1988-1990)]. | this study was conducted to investigate susceptibilities of clinical isolates to antibacterial agents at 149 hospitals throughout japan from september to december in both 1989 and 1990. in this study, identifications and susceptibility testings were carried out at each hospital laboratory. the susceptibility testings were performed according to the disk diffusion method recommended by nccls. staphylococcus aureus and coagulase-negative staphylococci showed high or moderate resistance rates to be ... | 1993 | 8360981 |
| analysis of intestinal flora of a patient with congenital absence of the portal vein. | a 14-year-old female patient, admitted for a closer examination of liver tumour (hepatocellular adenoma), was diagnosed as having a congenital absence of the portal vein. the blood ammonia level (approximately 120 micrograms dl-1) in the superior mesenteric vein was markedly low compared to the normal value of 300-350 micrograms dl-1 in the portal vein. the decreased ammonia concentration and urease activity of the patient's faeces were demonstrated. the dominant intestinal flora in the faeces o ... | 1993 | 8364525 |
| resistance to third-generation cephalosporins in barbados. | resistance to third-generation, or extended-spectrum, cephalosporins caused by induction of class i beta-lactamases has been reported rarely from developing countries. seven isolates of cephalosporin-resistant gram-negative rods were recovered recently from urine, burns and ulcers in the queen elizabeth hospital, barbados. the isolates were identified as acinetobacter calcoaceticus (2), citrobacter freundii (1), enterobacter cloacae (1), morganella morganii (1), providencia stuartii (1) and prot ... | 1993 | 8367967 |
| determinants of the activity of beta-lactamase inhibitor combinations. | inhibitor combinations provide one strategy to overcome beta-lactamase-mediated resistance. their success depends, obviously, on the inhibitor being able to bind and inactivate the beta-lactamase molecules. clavulanate, sulbactam and tazobactam are irreversible inactivators of many beta-lactamases, forming covalent complexes which resist hydrolysis. 'suicide' kinetics are seen with some, but not all, enzymes. all three compounds inactivate staphylococcal penicillinase, the chromosomal beta-lacta ... | 1993 | 8449836 |
| classification, pathogenicity, and drug susceptibility of hemolytic gram-negative bacteria isolated from sick or dead chickens. | fifteen hemolytic gram-negative bacteria were isolated from the respiratory tracts of sick birds suffering from a long-lasting respiratory syndrome or from the bone marrow of dead birds distributed in the southern part of taiwan. these were classified as pseudomonas aeruginosa (10 isolates), pseudomonas fluorescens (2 isolates), pseudomonas stutzeri (1 isolate), pasteurella haemolytica (1 isolate), and proteus morganii (1 isolate). each isolate was inoculated intraperitoneally into one group of ... | 1993 | 8452510 |
| the activity of cefpirome and ten other antibacterial agents against 2858 clinical isolates collected from 20 centres. | two thousand eight hundred and fifty-eight aerobic clinical isolates of enterobacteriaceae, pseudomonas species, staphylococci, streptococci and haemophilus species were collected in 19 geographically separated centres in the uk and one in ireland. the identity of each isolate was confirmed at southmead hospital and the mic of cefpirome, cefotaxime, ceftazidime, cefuroxime, cephradine, amoxycillin, piperacillin, imipenem, gentamicin, ciprofloxacin and trimethoprim was determined by an agar dilut ... | 1993 | 8486569 |
| [antimicrobial susceptibility patterns of the proteeae in japan, 1989]. | we discussed the antimicrobial susceptibilities of proteeae isolated in japan, 1989. eight hundred six clinical isolates were collected from 47 hospitals. these were comprised of 431 strains of proteus mirabilis, 155 proteus vulgaris, 154 morganella morganii, 44 providencia rettgeri and 22 providencia stuartii. antibiotics tested in this study were 2 penicillins, 5 cephems, 1 carbapenem and 2 aminoglycosides. the mic's were determined using the standard method of the japan society of chemotherap ... | 1993 | 8515560 |
| in vitro activity of e-4868, a new fluoroquinolone with a 7-azetidin ring, compared with ciprofloxacin, ofloxacin and fleroxacin. | e-4868, (-)-7[3-(r)-amino-2-(s)-methyl-1-azetidinyl]-1-(2,4- difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-3-quinolinecarboxylic acid, is a new fluoroquinolone with a 7-azetidin ring substituent. the in vitro activity against clinical isolates was compared with that of ciprofloxacin, ofloxacin and fleroxacin. in general, activity of e-4868 against aerobic and facultative anaerobic gram-negative bacilli was equal to or slightly less active than ciprofloxacin with the exception of morganella morganii ... | 1995 | 8529525 |
| ferric rhizoferrin uptake into morganella morganii: characterization of genes involved in the uptake of a polyhydroxycarboxylate siderophore. | iron uptake in morganella morganii, mediated by the fungal siderophore rhizoferrin, was studied. a mud1 insertion mutant devoid of growth on ferric rhizoferrin was complemented by a chromosomal dna fragment of m. morganii that encoded an outer membrane protein and a periplasmic protein named ruma and rumb (for rhizoferrin uptake into morganella spp.), respectively. ruma and rumb have the same transcription polarity and are probably cotranscribed from an iron-regulated promoter upstream of ruma. ... | 1996 | 8550472 |
| turkey rhinotracheitis virus isolated from broiler chicken with swollen head syndrome in japan. | turkey rhinotracheitis (trt) virus was first isolated from a commercial broiler chicken with swollen head syndrome (shs) in japan. at the same time, newcastle disease virus (ndv), infectious bronchitis virus (ibv), avian reovirus (arv), escherichia coli (e.coli), morganella morganii, and proteus mirabilis were also isolated from the same broiler chicken. the presence of antibodies to trt virus was confirmed in the sera of 34-day-old chickens of the flock with shs, however the antibodies to trt v ... | 1995 | 8593307 |
| characterization of bacterial cytochrome cd(1)-nitrite reductase as one enzyme responsible for catalysis of nitrosation of secondary amines. | bacterial formation of carcinogenic n-nitroso compounds may play a role in the etiology of human cancer. biochemical and immunological studies in denitrifying bacteria (pseudomonas aeruginosa) strongly support the identification of cytochrome cd(1)-nitrite reductase as the enzyme responsible for the catalysis of nitrosation through the production of nitric oxide or no(+)-like species. interestingly, electron paramagnetic resonance studies have shown that large quantities of nitric oxide or no(+) ... | 1996 | 8631140 |
| [clinical and laboratory significance of inducible beta-lactamases]. | many species of bacteria have inducible expression of beta-lactamase and the enzyme production in these bacteria is normally held at a low level by a repressor mechanism, but in the presence of a beta-lactamase inducer this repression is lifted and enzyme production is greatly increased. inducible synthesis of beta-lactamase was first described for the gram-positive organism bacillus licheniformis. after that inducible expression of beta-lactamase was discovered in gram-negative bacteria like en ... | 1995 | 8643019 |
| morganella morganii pericarditis after resolvent splenectomy for immune pancytopenia following allogeneic bone marrow transplantation for acute lymphoblastic leukemia. | | 1995 | 8645811 |
| incidence of histamine-forming bacteria and histamine content in scombroid fish species from retail markets in the barcelona area. | incidence and diversity of histidine decarboxylating bacteria were determined in samples of tunafish, bonito and mackerel purchased at different retail markets. histamine-forming bacteria occurred in a low proportion and always accounted for less than 0.1% of the total bacterial load in the fish samples studied. similarly, histamine content in fish samples also was low ( < 25 ppm) and all of them met current histamine standards established by the european union. histamine was found in 83.3% of t ... | 1996 | 8652349 |
| belgian multicentre study on the in vitro activity of cefepime against gram-negative bacilli. | the in vitro activity of cefepime has been compared with that of cefotaxime, ceftazidime, aztreonam, and piperacillin against 1826 enterobacteriaceae including 537 inducible enterobacteriaceae (enterobacter spp., serratia spp., citrobacter spp,. morganella morganii) and 572 non-fermenters, including 401 pseudomonas aeruginosa and 111 acinebacter spp. isolated from hospitalized patients in 28 belgian hospitals. overall, cefepime was found substantially more active than the third-generation cephal ... | 1996 | 8669160 |
| isolation and characterisation of dog uropathogenic proteus mirabilis strains. | proteus mirabilis strains isolated from the urine of dogs with urinary tract infections, were characterised with respect to the production of haemolysin and fimbriae. in contrast to healthy dogs, p. mirabilis was also isolated in high numbers from the faeces of dogs suffering from recurrent urinary tract infections. production of fimbriae was demonstrated by electron microscopy and the presence of genes for two different types of major fimbrial subunits (mr/p-like or uca-like) was demonstrated b ... | 1996 | 8701578 |