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utility of serial rectal swab cultures for detection of ceftazidime- and imipenem-resistant gram-negative bacilli from patients in the intensive care unit.forty-four patients receiving intensive care were studied prospectively to assess the utility of serial rectal swab cultures and clinical correlates of resistance for pseudomonas aeruginosa, enterobacter spp., citrobacter spp., morganella morganii, and serratia marcescens strains resistant to ceftazidime or imipenem. strains of pseudomonas aeruginosa, enterobacter spp., citrobacter spp., or morganella morganii were found in 26 of 44 (59%) patients: 17 (65%) in clinical sites (11 with concomitant ...19989865988
morganella morganii early onset sepsis. 19989877376
[descriptive study of infections caused by central venous catheters with peripheral insertion].to know the infection rate for central venous catheters inserted via a peripheral vein (cvcipv), the microorganisms involved, and the incidence of complications derived from catheter infections.19989934059
the most frequent aminoglycoside resistance mechanisms--changes with time and geographic area: a reflection of aminoglycoside usage patterns? aminoglycoside resistance study groups.the aminoglycoside resistance mechanisms revealed by two surveys in europe and other countries have been compared to those revealed in earlier studies. mechanisms have become more complex in all bacterial groups. in providencia, serratia, pseudomonas, acinetobacter, and staphylococcus species isolates, genus-specific mechanisms were very common, and it was not possible to see differences between different geographic areas. in other enterobacteriaceae, the increasing complexity of mechanisms was ...19978994779
upper urinary tract stones & ureaplasma urealyticum.extensive culture of stones and of pre-operative and renal pelvic urine for isolation of bacteria and ureaplasma urealyticum were performed in 70 patients of nephrolithiasis. stones were subjected to biochemical analysis and scanning electron microscopy. micro-organisms were isolated from 33 (47%) of 70 renal stones. of the 38 species of micro-organisms isolated, 14 were urea-splitting (u. urealyticum 2; klebsiella pneumoniae 8; morganella morganii 1; acinetobacter spp 3) and 24 were nonurea spl ...19979029830
the in-vitro activity of faropenem, a novel oral penem.the in-vitro activity of faropenem, a novel oral penem, was studied in comparison with other beta-lactam antimicrobials against 711 recent clinical isolates including gram-negative, gram-positive and anaerobic bacteria. mic data showed that faropenem was active against most members of the enterobacteriaceae (mics < or = 4 mg/l), with reduced activity against serratia spp. (mic90 = 32 mg/l). in common with its comparators, faropenem had weak activity against pseudomonas aeruginosa and stenotropho ...19979044026
morganella morganii postoperative endophthalmitis. 19979059257
cloning and sequencing of the gene encoding the ampc beta-lactamase of morganella morganii.the chromosomal beta-lactamase gene of a clinical isolate of morganella morganii was cloned in escherichia coli and sequenced. the beta-lactamase had a pi of 7.4 and conferred a typical ampc susceptibility pattern. the insert obtained was found to encode a protein of 379 amino acids. its deduced amino acid sequence revealed it to be a class c beta-lactamase: 39-56% identity with chromosomal ampc beta-lactamases of serratia marcescens, yersinia enterocolitica, citrobacter freundii, enterobacter c ...19979066104
bactericidal activity of cefodizime on enterobacteriaceae in an in-vitro model simulating plasma pharmacokinetics in humans.an in-vitro dialysis model was employed to assess the feasibility of once-daily dosing of cefodizime in the treatment of infections caused by various enterobacteriaceae: escherichia coli, klebsiella pneumoniae, morganella morganii, serratia marcescens, providencia stuartii and enterobacter cloacae. this model simulated the concentrations of cefodizime detected in human blood after an intravenous (i.v.) bolus injection of 1 g or 2 g of the antibiotic. validation of the model was undertaken to con ...19979069535
antibacterial activity of bms-180680, a new catechol-containing monobactam.the in vitro activities of a new catechol-containing monobactam, bms-180680 (sq 84,100), were compared to those of aztreonam, ceftazidime, imipenem, piperacillin-tazobactam, ciprofloxacin, amikacin, and trimethoprim-sulfamethoxazole. bms-180680 was often the most active compound against many species of the family enterobacteriaceae, with mics at which 90% of the isolates were inhibited (mic90s) of < or = 0.5 microg/ml for escherichia coli, klebsiella spp., citrobacter diversus, enterobacter aero ...19979145861
[validation of tkt medium for detection of streptococcus agalactiae in bulk milk samples].a selective medium for quantitative determination of streptococcus agalactiae in bulk milk samples was tested. among the medium bases, edwards medium (ew) supplemented with 6 to 9% (v/v) of carefully washed sheep erythrocytes was proved to be best (tab. v). the production of sphingomyelinasis c (bhe, tab. ii) or d (corex, tab. i) as a supplement supporting the formation of specific hemolytic zones in the medium, was tested in four strains of staphylococcus aureus and seven strains of corynebacte ...19979182394
susceptibility pattern of uropathogenic gram negative bacilli to antimicrobial chemotherapeutic agents in a national hospital in dar es salaam.in a period of two months, 232 consecutive urinary tract pathogens were isolated from hospitalised and non-hospitalised patients. among the isolates, 200 (86.2%) were gram negative bacilli, including e. coli 109 (54.5%), klebsiella species, 44 (22.5%), enterobacter species 19 (9.5%), proteus species 18 (9%), morganella morganii 9 (4.5%) and salmonella typhimurium, one (0.5%). antimicrobial susceptibility testing to amoxycillin/clavulanic acid, nitrofurantoin, gentamicin and cefuroxime was perfor ...19979185413
in-vitro activity of trovafloxacin against sensitive and resistant aerobic bacteria using the standard microdilution broth method and etest.a comparison of mics of trovafloxacin (cp-99,219) determined by the standard microdilution broth method versus the etest was performed for multiple strains of gram-positive and gram-negative bacteria. a comparison was also made of the in-vitro activity of trovafloxacin versus ciprofloxacin and ofloxacin. the mic50 and mic90 were determined by both methods for each species tested. the etest resulted in mics one to two dilutions higher than the microdilution broth method. trovafloxacin was the mos ...19979222068
morganella morganii: a newly reported, rare cause of neonatal sepsis.this case report reviews the clinical course of an 11-day-old boy who developed late-onset neonatal sepsis secondary to a rare neonatal pathogen, morganella morganii. this gram-negative enteric bacterium, within the enterobacteriaceae family, has most commonly been a nosocomial pathogen in debilitated, postsurgical patients. like many other enterobacteriaceae, m. morganii has an inducible beta-lactamase and is resistant to multiple antibiotics. when caring for neonates with culture-proven m. mor ...19979223696
occurrence and detection of extended-spectrum beta-lactamases in members of the family enterobacteriaceae at a veterans medical center: seek and you may find.a total of 907 consecutive isolates of members of the family enterobacteriaceae recovered during a 20-week period were tested for production of extended-spectrum beta-lactamases (esbls) by the double-disk (dd) potentiation method. of 84 dd-positive isolates, 83 (9.2%) produced esbls based on isoelectric focusing. shv-derived esbls and several tem-derived esbls were present in nine species, including the first isolate of citrobacter koserii and morganella morganii known to harbor an shv-derived e ...19979316913
plasmid-encoded fosfomycin resistance in bacteria isolated from the urinary tract in a multicentre survey.sixty out of 219 fosfomycin-resistant bacteria selected from more than 7400 urinary pathogens in an epidemiological multicentre survey performed in italy were screened for plasmid genes fosa and fosb conferring fosfomycin resistance. only five strains, three enterobacteria and two staphylococci, carried plasmids harbouring, respectively, fosa and fosb genes. fosfomycin resistance in the other isolates was caused by an alteration of the chromosomally encoded glpt transport system. one strain, mor ...19979338493
evaluation of bbl chromagar orientation medium for detection and presumptive identification of urinary tract pathogens.the microbiological performance of bbl chromagar orientation medium and cps id2 agar was compared to that of columbia agar with 5% sheep blood and macconkey agar without crystal violet for the enumeration and presumptive identification of bacteria responsible for urinary tract infections. of a total of 658 clinical urine specimens, 118 specimens yielded no growth, 402 specimens yielded growth with cell counts of > or = 10(5) cfu/ml, and 138 specimens yielded growth with cell counts of < 10(5) cf ...19979350731
relapsing henoch-schönlein purpura associated with a tubo-ovarian abscess due to morganella morganii.henoch-schönlein purpura is the most common vasculitis in children. it is frequently preceded by either viral or bacterial infections of the upper respiratory tract. we present a 15-year-old female who developed recurrent episodes of henoch-schönlein purpura. eventual investigation of the patient's abdominal pain, initially attributed to vasculitis involving the gastrointestinal tract, revealed a left tubo-ovarian abscess caused by morganella morganii. salpingo-oophorectomy resulted in complete ...19979382169
3-methylaspartate ammonia-lyase as a marker enzyme of the mesaconate pathway for (s)-glutamate fermentation in enterobacteriaceae.the enzyme 3-methylaspartase (3-methylaspartate ammonia-lyase, ec 4. 3.1.2) was found in the cells of enteric bacteria, especially in the genera citrobacter and morganella, that were grown under anoxic and oxygen-limited conditions. the enzymes were purified to homogeneity from the cell-free extracts of 18 active strains and had similar enzymological properties such as action on columns, specific activity, molecular weight, subunit structure, and n-terminal amino acid sequence similarity. the pr ...19979385136
[monotherapy with meropenem in febrile granulocytopenic patients].infection remains the major cause of morbidity and mortality for cancer patients who become granulocytopenic. combinations of beta-lactams plus aminoglycosides have been the standard empiric therapy for febrile granulocytopenic patients, especially those with profound long-lasting granulocytopenia. the advent of new broad-spectrum cephalosporins and carbapenems has favoured the possibility of empiric monotherapy. meropenem is a parenteral carbapenem antibiotic stable to renal dehydropeptidase-i ...19979410073
nitrate-reducing bacteria in diversion colitis: a clue to inflammation?a pathogenic role of nitric oxide has been suggested in acute and chronic intestinal inflammation. we took the opportunity offered by studies in patients with excluded colon, which represents a model of chronic intestinal inflammation with no exogenous nitrite or nitrate supply, to evaluate the quantity and the quality of nitrate reducers in diversion colitis. thirty patients (17 men, 13 women, mean age 45 years) having an excluded colon for various reasons were sampled by rectal swabs and compa ...19979440640
changing trends in frequency and antimicrobial resistance of urinary pathogens in outpatient clinics and a hospital in southern israel, 1991-1995.in order to monitor changes in the frequency and antimicrobial resistance of urinary pathogens over several years, urinary cultures received from outpatient clinics and from a hospital during a period of one month each in 1991 and 1995 were analyzed at a clinical microbiology laboratory. in 1991 and 1995, 1366 and 1534 significant monomicrobic cultures respectively were reviewed. the frequency of escherichia coli dropped significantly in the outpatient clinics from 70.5% to 61.2% (p < 0.0001). t ...19979447906
high frequency of antibiotic resistance among gram-negative isolates in intensive care units at 10 swedish hospitals.objective: to investigate the resistance rates among gram-negative isolates in swedish intensive care units (icus). methods: during 1994-95, members of the swedish study group collected, on clinical indication, 502 consecutive initial isolates of gram-negative bacteria from patients admitted to icus at 10 swedish hospitals and performed minimal inhibitory concentration (mic) determinations with the etest. breakpoints were defined according to the criteria of the swedish reference group for antib ...199711864106
coordination chemistry of the carboxylate type siderophore rhizoferrin: the iron(iii) complex and its metal analogs.rhizoferrin is a member of a new class of siderophores (microbial iron transport compounds) based on carboxylate and hydroxy donor groups rather than the commonly encountered hydroxamates and catecholates. we have studied the coordination chemistry of rhizoferrin (rf), as a representative of this group, with fe(3+), rh(3+), cr(3+), al(3+), ga(3+), vo(2+), and cu(2+). the metal complexes have been studied by uv-vis, cd, nmr, and epr spectroscopies and mass spectrometry. the formation constants fo ...199611666790
prevalence of pathogenic role of morganella-proteus providencia-group of bacteria in human faeces.speculation in literature that organisms of the morganella-proteus-providencia (mpp) group can cause diarrhoea led to the present studies which investigated their occurrence and pathogenic role in human faeces. faecal specimens were collected from a total of 307 subjects, 80 of which were from diarrhoea cases and 277 from healthy controls. ninety-two species of the mpp (24/80 diarrhoea and 68/277 control) were isolated from 30% of all subjects. none of the species of the mpp group was significan ...19969110049
[fluoroquinolone and aminoglycoside resistance in chromosomal cephalosporinase-overproducing gram-negative bacilli strains with inducible beta-lactamase].the increasing prevalence of stable derepressed mutants over-producers of type i chromosomal cephalosporinase in inducible enterobacteriaceae and pseudomonas aeruginosa challenges the adequacy of third generation cephalosporins in the empirical treatment of certain nosocomial infections. we sought to determine the frequency of stable over-producers of type i enzyme and their associated resistance to fluoroquinolones and aminoglycosides.19969044634
[antimicrobial activities of cefetamet against clinical isolates from urinary tract infection].in order to evaluate antimicrobial activity of cefetamet (cemt), minimum inhibitory concentrations (mics) of cemt and control drugs were determined against gram-negative rods mainly from complicated urinary tract infections examined in our laboratory from april to september of 1994. the results are summarized as follows; 1. the obtained strains were citrobacter diversus 20, citrobacter freundii 30, enterobacter aerogenes 20, enterobacter cloacae 30, serratia marcescens 30, proteus mirabilis 30, ...19969032594
[cytolysins and homologous proteins produced by gram-negative bacteria. ii. hemolysins of aeromonas, serratia, proteus and morganella and proteins from gram-negative bacteria related to cytolysins].this article presents the genetic determination, synthesis and activation of hemolysins produced by mentioned above bacteria, as well as the possible role of these toxins in the pathogenicity. all these cytolysins are related to rtx proteins presented to the previous paper. the short information about cytotoxic proteins from other gram-negative bacteria (p. aeruginosa, k. pneumoniae, vibrionaceae, g. vaginalis) and homologous proteins from e. chrysanthemi and r. leguminosarum biovar viciae are a ...19969019745
pyomyositis caused by morganella morganii in a patient with aids. 19968838200
a study of nosocomial diarrhea in calcutta.nosocomial infection is a major problem in hospitalized patients, particularly those who are debilitated. these infections may manifest as diarrhea. the spectrum of infections agents causing nosocomial diarrhea in our country is not known.19968840619
a simple method to detect bacteriolytic enzymes produced by enterobacteriaceae.the production of bacteriolytic enzymes by enterobacteriaceae in various growth conditions was investigated. peptone-based media containing killed gram-negative cells facilitated detection of bacteriolytic enzyme production in the highest number of species. these belonged to the genera serratia, proteus, morganella and providencia. in contrast, escherichia coli, shigella, salmonella, klebsiella, enterobacter and citrobacter species did not produce bacteriolytic activities in any of the condition ...19968893522
a bifunctional urease enhances survival of pathogenic yersinia enterocolitica and morganella morganii at low ph.to infect a susceptible host, the gastrointestinal pathogen yersinia enterocolitica must survive passage through the acid environment of the stomach. in this study, we showed that y. enterocolitica serotype o8 survives buffered acidic conditions as low as ph 1.5 for long periods of time provided urea is available. acid tolerance required an unusual cytoplasmically located urease that was activated 780-fold by low-ph conditions. acid tolerance of helicobacter species has also been attributed to u ...19968932305
[antimicrobial activity of cefodizime against clinical isolates].in order to evaluate antimicrobial activity of cefodizime (cdzm), minimum inhibitory concentrations (mics) of cdzm and control drugs were determined against clinical isolates collected from nation-wide medical institutions and in our laboratory from september to december of 1992 and from september to december of 1995. the results are summarized as follows: 1. bacterial species with no or few strains resistant to cdzm included streptococcus pyogenes, haemophilus influenzae, citrobacter koseri, pr ...19968986558
scope of urinary pathogens isolated in the public health bacteriology laboratory, harare: antibiotic susceptibility patterns of isolates and incidence of haemolytic bacteria.to determine the scope of urinary pathogens isolated in the public health bacteriology laboratory, their antibiotic susceptibility patterns and the incidence of haemolytic bacteria in harare.19968990570
biochemical investigations of biogroups and subspecies of morganella morganii.we determined the subspecies and biogroup designations for 73 strains of morganella morganii principally recovered from routine clinical specimens. on the basis of trehalose fermentation, 90% of all strains were identified as m. morganii subsp. morganii (trehalose negative), while the remaining 10% were designated m. morganii subsp. sibonii (trehalose positive). using three tests (ornithine decarboxylase [odc] and lysine decarboxylase [ldc] activities and susceptibility to tetracycline), we dete ...19968748284
identification and characterization of phon-sf, a gene on the large plasmid of shigella flexneri 2a encoding a nonspecific phosphatase.a gene encoding a nonspecific phosphatase, named phon-sf, was identified on the large virulence plasmid (pmysh6000) of shigella flexneri 2a ysh6000. the phosphatase activity in ysh6000 was observed under high-phosphate conditions. however, it was found that low-phosphate conditions induced a slightly higher level of activity. the nucleotide sequence of the phon-sf region cloned from pmysh6000 possessing the phon-sf gene encoded 249 amino acids with a typical signal sequence at the n terminus. th ...19968755883
inhibitory effect of spices on in vitro histamine production and histidine decarboxylase activity of morganella morganii and on the biogenic amine formation in mackerel stored at 30 degrees c.the inhibitory effects of clove, cinnamon, cardamom, turmeric and pepper on the histamine production and histidine decarboxylase activity of morganella morganii (a potent histamine-producing bacteria in fish) was examined at 30 degrees c using hplc. cinnamon and clove exhibited a significant (p < 0.01) inhibitory effect, whereas turmeric and cardamom had a moderate effect. these spices were applied to whole mackerel at a level of 3% and their inhibitory effect on biogenic amine formation at 30 d ...19968765991
prevalence, antimicrobial properties and beta-lactamase production of haemolytic enterobacteria in patients with diarrhoea and urinary tract infections in legos, nigeria.to determine the prevalence, antimicrobial properties and beta-lactamase production of haemolytic enterobacteria in patients with diarrhoea and urinary tract infections in lagos, nigeria.19968771935
[in vitro antibacterial activity of a new parenteral penem, sulopenem].eighty percent minimum inhibitory concentrations (mic80) of sulopenem against clinically isolated 12 to 80 strains of each of different bacteria were as follows: methicillin-susceptible staphylococcus aureus (mssa): 0.20 micrograms/ml, methicillin-resistant s. aureus (mrsa): 50 micrograms/ml, coagulase-negative staphylococci: 3.13 micrograms/ml, streptococcus pyogenes: < or = 0.013 microgram/ml, streptococcus pneumoniae: < or = 0.013 microgram/ml, beta-streptococci: 0.05 microgram/ml, enterococc ...19968786624
[in vitro and in vivo antibacterial activities of sulopenem, a new penem antibiotic].the in vitro and in vivo antibacterial activities of sulopenem, a new penem, were evaluated in comparison with imipenem (ipm), meropenem (mepm), ceftazidime (caz) and flomoxef (fmox). sulopenem had broad and potent antibacterial spectra against gram-positive and gram-negative bacteria, including enterococcus faecalis, proteus vulgaris, morganella morganii, enterobacter spp. and citrobacter freundii. sulopenem showed concentration-dependent bactericidal activities against staphylococcus aureus, e ...19968786626
[putaminal abscess occurring at the site of hemorrhage: a case report].brain abscesses following stroke have been reported only rarely. we presented a case of putaminal abscess following putaminal hemorrhage. the patient was admitted to our hospital because of acute onset of left hemiplegia. the size of the hematoma was medium and the patient was conservatively treated. in about two months after the ictus, he became intermittently febrile and laboratory examinations suggested the presence of general infections including meningitis. meanwhile, ct and mri revealed cl ...19968827738
[antimicrobial activities of tosufloxacin against recently obtained clinical isolates].to evaluate antimicrobial activities of tosufloxacin (tflx), minimum inhibitory concentrations (mics) of tflx and other drugs were determined against clinical isolates that were obtained in our laboratory from february of 1993 to january of 1994 (period i), and from february of 1995 to january of 1996 (period ii). the results are summarized as follows: 1. compared to mic90's reported by others for tflx in the 1980's, those obtained by us against beta-streptococci, streptococcus pneumoniae, pepto ...19968828073
ferric rhizoferrin uptake into morganella morganii: characterization of genes involved in the uptake of a polyhydroxycarboxylate siderophore.iron uptake in morganella morganii, mediated by the fungal siderophore rhizoferrin, was studied. a mud1 insertion mutant devoid of growth on ferric rhizoferrin was complemented by a chromosomal dna fragment of m. morganii that encoded an outer membrane protein and a periplasmic protein named ruma and rumb (for rhizoferrin uptake into morganella spp.), respectively. ruma and rumb have the same transcription polarity and are probably cotranscribed from an iron-regulated promoter upstream of ruma. ...19968550472
incidence of histamine-forming bacteria and histamine content in scombroid fish species from retail markets in the barcelona area.incidence and diversity of histidine decarboxylating bacteria were determined in samples of tunafish, bonito and mackerel purchased at different retail markets. histamine-forming bacteria occurred in a low proportion and always accounted for less than 0.1% of the total bacterial load in the fish samples studied. similarly, histamine content in fish samples also was low ( < 25 ppm) and all of them met current histamine standards established by the european union. histamine was found in 83.3% of t ...19968652349
belgian multicentre study on the in vitro activity of cefepime against gram-negative bacilli.the in vitro activity of cefepime has been compared with that of cefotaxime, ceftazidime, aztreonam, and piperacillin against 1826 enterobacteriaceae including 537 inducible enterobacteriaceae (enterobacter spp., serratia spp., citrobacter spp,. morganella morganii) and 572 non-fermenters, including 401 pseudomonas aeruginosa and 111 acinebacter spp. isolated from hospitalized patients in 28 belgian hospitals. overall, cefepime was found substantially more active than the third-generation cephal ...19968669160
isolation and characterisation of dog uropathogenic proteus mirabilis strains.proteus mirabilis strains isolated from the urine of dogs with urinary tract infections, were characterised with respect to the production of haemolysin and fimbriae. in contrast to healthy dogs, p. mirabilis was also isolated in high numbers from the faeces of dogs suffering from recurrent urinary tract infections. production of fimbriae was demonstrated by electron microscopy and the presence of genes for two different types of major fimbrial subunits (mr/p-like or uca-like) was demonstrated b ...19968701578
piperacillin/tazobactam in the treatment of hospitalized patients with urinary tract infections: an open non-comparative and multicentered trial.the aim of this multicentered, prospective and open study was to determine the clinical and bacteriological efficacy and safety of piperacillin/tazobactam (4g/500 mg iv tid) in the treatment of 79 adult patients with complicated urinary tract infections (uti) requiring hospitalization. forty-seven women and 32 men (mean age 54.2 years, and range 21-91) from 4 argentinean and 6 mexican hospitals were enrolled. sixty-one clinically and bacteriologically evaluable patients were treated for a mean o ...19968708743
distribution of diaminopropane and acetylspermidine in enterobacteriaceae.polyamines of 97 strains (60 species) belonging to 18 genera of the family enterobacteriaceae were determined by high performance liquid chromatographic analysis. in addition to putrescine and cadavarine, diaminopropane was widely distributed in enterobacteriaceae and almost ubiquitously within enterobacter, pantoea, erwinia, leminorella, proteus, leclercia, morganella, klebsiella, hafnia, rahnella, serratia, and tatumella species and sporadically within citrobacter, escherichia, moellerella, pr ...19968742354
comparative in vitro studies on the beta-lactamase-inhibiting effect of clavulanic acid and sulbactam on ampicillin-resistant enterobacteriaceae.clavulanic acid and sulbactam alone are ineffective against pseudomonas and enterococci. staphylococci and enterobacteriaceae are inhibited by high concentrations not attainable under clinical conditions. strains of acinetobacter, especially a. lwoffii are susceptible to clavulanic acid and highly susceptible to sulbactam. the ampicillin/sulbactam combination is superior to ampicillin/clavulanic acid against citrobacter freundii, enterobacter spp. and morganella morganii. the latter combination ...199618611726
in vitro activity of e-4868, a new fluoroquinolone with a 7-azetidin ring, compared with ciprofloxacin, ofloxacin and fleroxacin.e-4868, (-)-7[3-(r)-amino-2-(s)-methyl-1-azetidinyl]-1-(2,4- difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-3-quinolinecarboxylic acid, is a new fluoroquinolone with a 7-azetidin ring substituent. the in vitro activity against clinical isolates was compared with that of ciprofloxacin, ofloxacin and fleroxacin. in general, activity of e-4868 against aerobic and facultative anaerobic gram-negative bacilli was equal to or slightly less active than ciprofloxacin with the exception of morganella morganii ...19958529525
[value of media containing chromogenic substrates for the identification and the listing of urinary bacteria].performance in terms of enumeration, growth and identification with a new culture medium (cps id2, biomérieux) was evaluated using 405 urine samples and 244 collection strains. the cps id2 medium contains chromogenic substrates enabling the detection of 4 bacterial enzymes which leads to the identification of colonies: escherichia coli, proteus mirabilis, proteus-morganella-providencia and enterococci. no discrepancies in the enumeration were observed with the collected strains and urine samples ...19958746095
regulation of the escherichia coli s10 ribosomal protein operon by heterologous l4 ribosomal proteins.we have cloned the l4 ribosomal protein genes from morganella morganii and haemophilus influenza. the sequences of these genes were compared with published sequences for escherichia coli, yersinia pseudotuberculosis, and bacillus stearothermophilus. all five of these l4 genes were expressed in e. coli and shown to function as repressors of both transcription and translation of the e. coli s10 operon. possible implications for regulation of r-protein synthesis in species other e. coli are discuss ...19958722027
turkey rhinotracheitis virus isolated from broiler chicken with swollen head syndrome in japan.turkey rhinotracheitis (trt) virus was first isolated from a commercial broiler chicken with swollen head syndrome (shs) in japan. at the same time, newcastle disease virus (ndv), infectious bronchitis virus (ibv), avian reovirus (arv), escherichia coli (e.coli), morganella morganii, and proteus mirabilis were also isolated from the same broiler chicken. the presence of antibodies to trt virus was confirmed in the sera of 34-day-old chickens of the flock with shs, however the antibodies to trt v ...19958593307
the most frequently occurring aminoglycoside resistance mechanisms--combined results of surveys in eight regions of the world. the aminoglycoside resistance study groups.aminoglycoside-resistant isolates from different patients were collected in 149 hospitals in eight regions of the world. aminoglycoside resistance mechanisms were determined in 11,079 of these isolates by the correlation of resistance phenotypes to 12 aminoglycosides and dna hybridisation with up to 19 resistance genes. a very large diversity of different resistance mechanisms was found. for example, in escherichia-morganella-proteus-salmonella-shigella, at total of 53 different mechanisms was f ...19958622108
the changing nature of aminoglycoside resistance mechanisms and the role of isepamicin--a new broad-spectrum aminoglycoside. the aminoglycoside resistance study groups.aminoglycoside resistance mechanisms from recent studies were compared with those found in earlier studies in the usa and europe for three pathogen groups. among citrobacter-enterobacter-klebsiella, four single mechanisms (aac(3)-ii, aac(3)-i, ant(2")-i and aac(6')-i were found in all studies, but the most recent studies showed a significant increase in combinations of aac(6')-i with the other common mechanisms. since aac(6')-i confers resistance to tobramycin, netilmicin and amikacin, combinati ...19958622109
[clinical and laboratory significance of inducible beta-lactamases].many species of bacteria have inducible expression of beta-lactamase and the enzyme production in these bacteria is normally held at a low level by a repressor mechanism, but in the presence of a beta-lactamase inducer this repression is lifted and enzyme production is greatly increased. inducible synthesis of beta-lactamase was first described for the gram-positive organism bacillus licheniformis. after that inducible expression of beta-lactamase was discovered in gram-negative bacteria like en ...19958643019
morganella morganii pericarditis after resolvent splenectomy for immune pancytopenia following allogeneic bone marrow transplantation for acute lymphoblastic leukemia. 19958645811
cloning and characterization of the napa acid phosphatase/phosphotransferase of morganella morganii: identification of a new family of bacterial acid-phosphatase-encoding genes.the gene encoding a minor phosphate-irrepressible acid phosphatase (named napa) of morganella morganii was cloned and sequenced, and its product characterized. napa is a secreted acid phosphatase composed of four 27 kda polypeptide subunits. the enzyme is active on several organic phosphate monoesters but not on diesters, and is also endowed with transphosphorylating activity from organic phosphoric acid esters to nucleosides and other compounds with free hydroxyl groups. its activity is inhibit ...19957894706
commensal enteric bacteria engender a self-limiting humoral mucosal immune response while permanently colonizing the gut.we have employed a germfree mouse model to study the development and persistence of a humoral mucosal immune response to a gram-negative murine commensal organism, morganella morganii. m. morganii bacteria rapidly colonize the gut, resulting in hypertrophy of peyer's patches (pp), including germinal center reactions (gcr), and the development of specific immunoglobulin a (iga) responses detected in vitro in pp fragment cultures and by elispot assays of lamina propria cells. the gcr peaks 14 days ...19957558298
the in-vitro activity of cp 99,219, a new naphthyridone antimicrobial agent: a comparison with fluoroquinolone agents.the in-vitro activity of a new fluoroquinolone, cp 99,219 was compared with that of ciprofloxacin, du 6859, sparfloxacin and levofloxacin. cp 99,219 showed generally similar in-vitro activity to the other compounds tested against the enterobacteriaceae (mic90 of all agents < 0.5 mg/l except morganella morganii). it was found to be more active than ciprofloxacin, sparfloxacin and levofloxacin against the strains of acinetobacter calcoaceticus tested (mic90 1 mg/l). cp 99,219 was found to be four- ...19957559198
[in vitro activity of six beta-lactams against 295 strains of enterobacteriaceae and p. aeruginosa isolated from neutropenic patients].the in vitro activity of two new beta-lactam agents, cefpirome (cpo) and cefepime (fep), was investigated against 295 gram-negative bacilli (250 enterobacteriaceae and 45 p. aeruginosa) isolated from neutropenic patients. they were compared with ceftazidime (caz), piperacillin-tazobactam (tzp), imipenem (ipm) and cefotaxime (ctx). all enterobacteriacae were susceptible to ipm, 16 strains were intermediately susceptible or resistant to caz (1 strain of e. coli, 4 of morganella morganii and 11 of ...19957567110
ceftibuten: a review of antimicrobial activity, spectrum and other microbiologic features.ceftibuten is a new, orally administered cephalosporin with exceptional beta-lactamase stability and potency against commonly isolated gram-negative pathogens. more than 90% of recent enterobacteriaceae clinical isolates were inhibited by < or = 8 micrograms/ml of ceftibuten. in only five enteric species (citrobacter freundii, enterobacter aerogenes, enterobacter cloacae, morganella morganii, serratia marcescens) were more than 15% of strains resistant (minimal inhibitory concentrations (mic, wi ...19957567314
proteus mirabilis amino acid deaminase: cloning, nucleotide sequence, and characterization of aad.proteus, providencia, and morganella species produce deaminases that generate alpha-keto acids from amino acids. the alpha-keto acid products are detected by the formation of colored iron complexes, raising the possibility that the enzyme functions to secure iron for these species, which do not produce traditional siderophores. a gene encoding an amino acid deaminase of uropathogenic proteus mirabilis was identified by screening a genomic library hosted in escherichia coli dh5 alpha for amino ac ...19957592338
toc-39, a novel parenteral broad-spectrum cephalosporin with excellent activity against methicillin-resistant staphylococcus aureus.toc-39, a new parenteral cephalosporin, is a hydroxyimino-type cephem antibiotic with vinylthio-pyridyl moiety at the 3 position. toc-39 was evaluated for antibacterial activity against various clinically isolated strains. toc-39 had excellent activity, stronger than that of methicillin, oxacillin, the cephalosporins tested, imipenem, gentamicin, minocycline, tobramycin, ofloxacin, and ciprofloxacin against methicillin-resistant staphylococcus aureus (mrsa) and had an mic comparable to that of v ...19957625799
comparative antibacterial activity of l-695,256, a carbapenem active against methicillin-resistant staphylococci.the activity of a new prototype carbapenem, l-695,256, against clinical isolates of gram-positive and gram-negative aerobes was studied in vitro by agar dilution. l-695,256 was highly active against methicillin-resistant and -susceptible isolates of staphylococci (mics, 0.016 to 2 micrograms/ml) and against penicillin-resistant pneumococci (mics, 0.016 to 0.064 micrograms/ml), irrespective of penicillin susceptibility. activity against members of the family enterobacteriaceae was less than that ...19957625810
head and neck infections in pediatric cardiac transplant patients.a retrospective chart review was undertaken at columbia presbyterian medical center to assess the incidence, etiology and management of head and neck infections in pediatric cardiac transplant patients on immunosuppression. from june 1984 to february 1992, 59 cardiac transplants were performed on 57 pediatric patients. standard immunosuppressive therapy was used. thirteen of these patients died within three months of transplant and were not included. of the 44 patient charts reviewed, 82 head an ...19957628334
laboratory data which differentiate meropenem and imipenem.meropenem and imipenem are carbapenems which are distinguishable from all other currently available beta-lactam antibiotics by breadth of antibacterial spectrum and stability to beta-lactamases, but can be differentiated one from another. meropenem is relatively stable to human renal dehydropeptidase-i (dhp-i); it does not require to be co-administered with cilastatin and consequently, unlike imipenem, will be administered as a single agent. in vitro both meropenem and imipenem are active agains ...19957652504
bactericidal activity of normal human serum against morganella, proteus, and providencia strains.the susceptibility od proteus, providencia, and morganella strains to bactericidal action of human serum was examined. the percentage of survival was determined after one and three hours incubation with 50% human serum. the susceptible strains were treated by serum preparations with blocked classical or alternative complement activation pathways as well as with lysozyme removed. following mechanisms of the bactericidal action of serum were found: complement activated by the classical or alternat ...19957660859
neonatal brain abscess caused by morganella morgagni. 19957742461
[comparison of mics of new quinolones obtained using agar-dilution and broth-microdilution procedures].minimum inhibitory concentrations (mic) of new quinolones against both gram-positive and gram-negative bacteria obtained using agar-dilution and broth-microdilution procedures were compared. a primary regression curve and a correlation coefficient (r) between 2 mics for each of ofloxacin, ciprofloxacin, tosufloxacin, sparfloxacin or balofloxacin were calculated. for the 5 quinolones, average correlation coefficients were 0.891 for the gram-positive bacteria tested, and 0.865 for the gram-negativ ...19957752452
a histidine decarboxylase gene encoded by the vibrio anguillarum plasmid pjm1 is essential for virulence: histamine is a precursor in the biosynthesis of anguibactin.we have identified and sequenced an hdc gene in the vibrio anguillarum plasmid pjm1 which encodes a histidine decarboxylase enzyme and is an essential component for the biosynthesis of anguibactin. the open reading frame corresponds to a protein of 386 amino acids with a calculated molecular mass of 44,259.69 da. the amino acid sequence has extensive homology with the pyridoxal-p-dependent histidine decarboxylases of morganella morganii, klebsiella planticola, and enterobacter aerogenes. tn3-hoh ...19957752899
purification and properties of crystalline 3-methylaspartase from two facultative anaerobes, citrobacter sp. strain yg-0504 and morganella morganii strain yg-0601.3-methylaspartase (3-methylaspartate ammonia-lyase, ec 4.3.1.2) from two facultative anaerobes from soil, citrobacter sp. strain yg-0504 and morganella morganii strain yg-0601, were purified and crystallized from their crude extracts. both of the citrobacter and morganella enzymes appeared to be a dimer of subunits of m(r) 40,000 and 44,000, respectively. the enzymes had similar enzymological properties: optimum ph for the deamination reaction of (2s,3s)-3-methylaspartic acid, substrate specific ...19957765982
in vitro activity of subinhibitory concentrations of quinolones on urea-splitting bacteria: effect on urease activity and on cell surface hydrophobicity.the effect of subinhibitory concentrations of ciprofloxacin, lomefloxacin, norfloxacin, ofloxacin, and sparfloxacin on urease activity and on cell surface hydrophobicity of urea-splitting bacteria was examined. quinolones at 0.5 mics demonstrated variable effects on bacterial-urease activity. norfloxacin inhibited enzyme activity in proteus vulgaris and proteus mirabilis, while other quinolones had no effects. in morganella morganii, sparfloxacin and ciprofloxacin enhanced urease activity, parti ...19957844396
[evaluation of the usefulness of tests for production of beta-d-glucuronidase and propylene glycol utilization for the differentiation of enterobacteriaceae rods].the aim of the study was to inquire about the diagnostic usefulness of determining the activity of glucuronidase and utilisation of propylene glycol in enterobacteriaceae rods. the study included 1511 strains: 411- e. coli, 278 - klebsiella, 231 - salmonella, 159 - yersinia, 97 - citrobacter, 75 - shigella and 260 strains representing 6 other kinds of enteric rods. determination was performed in a liquid medium containing in 1 ml 25 mcg mug and 100 mcg onpg. propylene glycol (pg) utilisation was ...19958833927
a comparative study of the bbl crystal enteric/nonfermenter identification system and the biomerieux api20e and api20ne identification systems after overnight incubation.the bbl crystal enteric/nonfermenter (crystal, becton dickinson microbiology systems) is a new multi-test identification system for gram negative rods requiring no oil overlay or addition of reagents. one hundred and three selected gram negative rod isolates from routine clinical specimens were tested in parallel using the appropriate api20e or api20ne (biomerieux) reading after overnight incubation. the isolates included in the study, and the number tested, were as follows: acinetobacter sp, 8; ...19958771156
in vitro activity of cp-99,219, a novel 7-(3-azabicyclo[3.1.0]hexyl) naphthyridone antimicrobial.the in vitro activity of cp-99,219 was compared with that of ciprofloxacin and sparfloxacin against 814 clinical bacterial isolates using a microdilution method with brain-heart infusion broth. cp-99,219 was the most potent agent tested against methicillin-resistant, ciprofloxacin-susceptible staphylocci (minimum inhibitory concentration [mic]90 < or = 0.25 microgram/ml). cp-99,219 was 32-fold and fourfold more potent than ciprofloxacin and sparfloxacin, respectively, against streptococcus pneum ...19947851087
[clinical study of a new injectable cephem, fk037, for acute bacterial prostatitis].fk037, a new injectable cephem antibiotic, was administered in the treatment of 13 acute bacterial prostatitis (mean age 53.5, range 30-79), and its effectiveness and safety were evaluated. the human prostatic fluid (pf) concentration of fk037 on 7 specimens 1 hour after 1 g i.v.d., was in the range of 0.87-7.47 micrograms/ml (mean +/- sd, 3.43 +/- 2.23 micrograms/ml), whereas, the serum concentration averaged 45.3 +/- 2.88 micrograms/ml, the ratio of pf/serum consequently being 0.08 +/- 0.05. i ...19947863869
comparative in vitro activity of fk-037, a new cephalosporin antibiotic.the in vitro activity of fk-037, a novel parenteral oxime-type cephalosporin, was compared with that of cefepime, cefpirome, ceftazidime, imipenem, and gentamicin against a total of 668 recent clinical isolates. minimum inhibitory concentrations were determined by a standard agar dilution procedure, and all isolates were tested at two inocula (10(4) and 10(6) colony forming units). fk-037 inhibited 90% of isolates of escherichia coli, klebsiella species, proteus mirabilis, p. vulgaris, morganell ...19947867295
microbiological surveillance during selective decontamination of the digestive tract (sdd)the use of selective decontamination of the digestive tract (sdd) as prophylaxis against nosocomial respiratory tract infection remains controversial, largely because of concerns that, in the long term, it may promote the emergence of antibiotic-resistant strains. this report describes the results of surveillance cultures and susceptibility testing undertaken during the course of a 2-year, double-blind study of the efficacy of sdd which was conducted in a respiratory intensive care unit (icu). s ...19947868405
morganella morganii meningitis in a patient with aids. 19947884233
comparative microbiological activity and pharmacokinetics of cefprozil.in vitro studies on the activity of cefprozil have been conducted in europe and north america. against gram-negative bacilli, cefprozil and cefaclor are at least two to four times more active than cephalexin. cefixime is more active against these organisms. against gram-positive cocci, cefprozil is at least two to four times more active than cefaclor and cephalexin; cefixime has limited gram-positive activity, and is particularly inactive against staphylococci (mic90 32 mg/l). cefprozil is highl ...19947889957
pore formation in artificial membranes by the secreted hemolysins of proteus vulgaris and morganella morganii.lipid-bilayer experiments were performed with the related hemolysins from proteus vulgaris and morganella morganii (hlya). the addition of the toxins to the aqueous phase bathing lipid-bilayer membranes composed of different lipids resulted in the formation of transient ion-permeable channels. membranes formed of pure lipids were rather inactive targets for the hemolysins as compared with lipid mixtures such as asolectin. the channels had several different substrates. the major open state had si ...19947510229
comparison of the antibody responses to the 77 klebsiella capsular types in ankylosing spondylitis and various rheumatic diseases.the production of antibodies to klebsiella capsular polysaccharides was measured in sera from either hla-b27-positive (hla-b27+) or hla-b27-negative (hla-b27-) patients with classical ankylosing spondylitis (n = 54). these sera were compared with sera from patients with various rheumatic diseases (n = 82) and hla-b27+ or hla-b27- healthy individuals (n = 85). all sera were analyzed by means of an enzyme-linked immunosorbent assay specific to each of the 77 klebsiella serotypes. the sera from hla ...19947927763
evaluation of different antimicrobial agents used as selective supplements for isolation and recovery of yersinia enterocolitica.seventeen antimicrobial agents were evaluated separately or in combination for their efficiency as selective supplements in a broth medium against six different serotypes of yersinia enterocolitica and 20 selected strains of different gram-negative bacteria. irgasan (dp300, 5-chloro-2-(2,4- dichlorophenoxy) phenol) at a concentration of 4 micrograms ml-1 inhibited the growth of most gram-negative bacteria with the exceptions of aeromonas hydrophila, morganella morganii, pseudomonas aeruginosa an ...19947928783
[antibacterial activities of isepamicin against fresh clinical isolates of gram-negative bacilli].to investigate antibacterial activities of isepamicin (isp), mics of isp as well as other aminoglycosides (ags) were determined against many strains of gram-negative bacilli that were clinically isolated in 1993. 1. no isp-resistant strains were observed among isolates of escherichia coli, citrobacter diversus, klebsiella spp., enterobacter spp. or proteus mirabilis. 2. isp-resistant strains were observed among isolates of citrobacter freundii, serratia spp., proteus vulgaris, morganella morgani ...19947933534
[multicenter evaluation of oral antibiotics: resistance behavior in 5 swiss centers].the susceptibility of 2196 fresh clinical isolates to twelve different oral compounds was assessed in five swiss microbiology institutions during summer 1992. a standardized microdilution system including all other material necessary was employed to assess the antibacterial activity of penicillin g, ampicillin, ampicillin + sulbactam, amoxycillin + clavulanic acid, cefadroxil, cephalexin, cefaclor, cefuroxime, cefetamet, doxycycline, erythromycin and clindamycin. the aminopenicillins (including ...19947939052
microbiological studies of abscesses complicating bothrops snakebite in humans: a prospective study.forty patients with abscesses at the site of bothrops bite were evaluated. ten brought the snake responsible for the bite, bothrops jararaca in all cases. on admission a sample was collected from each case for aerobic and anaerobic culture, and no abscesses drained spontaneously. none of the patients had received antibacterial therapy at this time. the bacteria most frequently isolated were morganella morganii (23 patients), providencia rettgeri (7) enterobacter sp. (4), escherichia coli (3), gr ...19947940580
in vitro activity of cefpirome against beta-lactamase-inducible and stably derepressed enterobacteriaceae.most members of the enterobacteriaceae and pseudomonas aeruginosa possess an inducible chromosomal class i beta-lactamase. bacterial strains which produce high levels of beta-lactamase constitutively can be isolated from infections; these derepressed mutants are responsible for resistance to third-generation cephalosporins and ureidopenicillins. minimum inhibitory concentrations of cefpirome, a fourth-generation cephalosporin, and other beta-lactam antibiotics were determined for a series of mut ...19947956454
human t helper cells reactive with somatic bacterial antigens belong to the th1 subset.the aim of this study was to characterize the cytokine secretion patterns of human t helper cells from healthy donors reactive with somatic antigens from various bacteria, the nematode anisakis and tetanus toxoid. from the peripheral blood of four healthy donors we have established 70 t cell lines reactive with antigens from yersinia, salmonella, morganella, klebsiella, serratia, escherichia, chlamydia, shigella, streptococcus, tetanus toxoid and anisakis, respectively. our results show that all ...19947997190
comparative in-vitro activity of biapenem against enterobacteria with beta-lactamase-mediated antibiotic resistance.the effects of enterobacterial beta-lactamases were studied for biapenem (l627), a new carbapenem. susceptibility tests were performed for isogenic mutant series of citrobacter freundii, enterobacter cloacae, morganella morganii, serratia marcescens and proteus vulgaris which varied only in chromosomal beta-lactamase expression. beta-lactamase-derepressed organisms in these series were as susceptible as beta-lactamase-inducible strains to biapenem; beta-lactamase-basal mutants were up to eight-f ...19948040111
[antibacterial activity of aztreonam against clinical isolates].to evaluate the antibacterial activity of a monobactam antibiotic, aztreonam (azt), mics of azt and other antibiotics against clinical isolates collected at 36 participating institutions after january 1992 were determined using the agar plate dilution method (size of inoculum, 10(6) cfu/ml) according to the japan society of chemotherapy standard. the antibiotics that were tested along with azt included piperacillin (pipc), cefoperazone (cpz), and amikacin (amk). azt was found to be more active a ...19948051793
characterization and sequence of phoc, the principal phosphate-irrepressible acid phosphatase of morganella morganii.phosphatase activities were investigated in morganella morganii, which is one of the few enterobacterial species producing high-level phosphate-irrepressible acid phosphatase activity (hpap phenotype), and the gene encoding the major phosphate-irrepressible acid phosphatase was cloned, sequenced, and its product characterized. using p-nitrophenyl phosphate as substrate, morganella produced a major phosphate-irrepressible acid phosphatase (named phoc) which is associated with the hpap phenotype, ...19948081499
in vitro antibacterial activity and beta-lactamase stability of sy5555, a new oral penem antibiotic.the antibacterial activity of sy5555, a new oral penem antibiotic, was compared with those of cefaclor, cefixime, and cefteram. sy5555 was more active than the comparison agents against methicillin-susceptible staphylococcus aureus, staphylococcus epidermidis, streptococcus pneumoniae, enterococcus faecalis, citrobacter freundii, enterobacter cloacae, morganella morganii, acinetobacter calcoaceticus, clostridium spp., and bacteroides fragilis. against providencia spp., proteus spp., and haemophi ...19947811005
isolation of three hexahydro-1,3,5-trinitro-1,3,5-triazine-degrading species of the family enterobacteriaceae from nitramine explosive-contaminated soil.three species of the family enterobacteriaceae that biochemically reduced hexahydro-1,3,5-trinitro-1,3,5-triazine (rdx) and octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (hmx) were isolated from nitramine explosive-contaminated soil. two isolates, identified as morganella morganii and providencia rettgeri, completely transformed both rdx and the nitroso-rdx reduction intermediates. the third isolate, identified as citrobacter freundii, partially transformed rdx and generated high concentratio ...19947811097
in vitro antimicrobial activity of cefpirome against ceftazidime-resistant isolates from two multicenter studies.the in vitro activity of cefpirome against ceftazidime-resistant (mic > 16 mg/l) isolates from two multicenter studies was analyzed. the first investigation carried out in the usa, was an in vitro comparison of cefpirome and five third-generation cephalosporins in which more than 6,000 isolates were evaluated, including 97 enterobacteriaceae and 1,509 staphylococci resistant to ceftazidime. the second study was a multicenter international study (> 5,000 strains total) in which 160 ceftazidime-re ...19947813503
spontaneous bacterial empyema and peritonitis caused by morganella morganii. 19948113596
pore-formation by escherichia coli hemolysin (hlya) and other members of the rtx toxins family.escherichia coli hemolysin (hlya) is a major cause of e. coli virulence. it lyses erythrocytes by a colloid osmotic shock due to the formation of hydrophilic pores in the cell wall. the size of these channels can be estimated using osmotic protectant of increasing dimensions. to show that the formation of pores does not depend critically on the osmotic swelling we prepared resealed human erythrocyte ghosts loaded with a fluorescent marker. when attacked by hlya the internal marker was released, ...19948160187
penetration of topically applied ciprofloxacin, norfloxacin, and ofloxacin into the aqueous humor.to determine the intraocular penetration of topically applied fluoroquinolone antibiotics into aqueous humor.19948190478
compositional analysis of peptidoglycan by high-performance anion-exchange chromatography.a high-performance anion-exchange chromatography method with pulsed-amperometric detection has been developed for the simultaneous analysis of both amino acids and amino sugars and applied to the compositional analysis of peptidoglycan hydrolysates. chromatography of the acid hydrolysis products was performed on a carbopac pa-1 anion-exchange column, with pulsed-amperometric detection. complete resolution of the two amino sugars (glucosamine and muramic acid) and eight of the nine amino acids (a ...19938214575
multicentre survey of the comparative in-vitro activity of piperacillin/tazobactam against bacteria from hospitalized patients in the british isles.twenty-nine british and irish hospitals each collected up to 300 bacterial isolates from in-patients. the organisms were identified by an appropriate api system or, for staphylococci, by their gram and coagulase reactions. disc susceptibility tests were performed. isolates that gave zones < or = 25 mm to piperacillin/tazobactam (75 micrograms + 10 micrograms) discs were sent to a central laboratory for re-examination and determination of mic, together with a sample of the more susceptible organi ...19938226427
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