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[microbiological quality of mechanically deboned beef].microbial quality of mechanically deboned beef (mdb), which was obtained by the discontinuous hydraulic horizontal separator, type inject-star (firm laska, austria), was analyzed for the presence of indicatory microorganisms (coliforms and enterococci), pathogenic and conditionally pathogenic microorganisms. the basic microbial parameters have been determined separately for mdb of 1st, 2nd degrees as well as for average daily samples from one collecting vessel. apart from it, also a raw material ...19912042400
detection of escherichia coli alpha-haemolysin genes and their expression in a human faecal strain of enterobacter cloacae.faecal samples of 200 infants were investigated for haemolytic enterobacteriaceae. forty infants were carrying alpha-haemolysin producing escherichia coli, two carried haemolytic strains of morganella morganii and one infant carried a haemolytic strain of enterobacter cloacae. the m. morganii and e. cloacae strains were found to produce alpha-haemolysin which was tested with a specific monoclonal antibody and by dna-hybridization with an alpha-haemolysin specific gene probe. to our knowledge thi ...19912044935
the efficacy of polysporin first aid antibiotic spray (polymyxin b sulfate and bacitracin zinc) against clinical burn wound isolates.polysporin first aid antibiotic spray (burroughs wellcome co., research triangle park, n.c.) is a dry spray containing 200,000 units aerosporin (polymyxin b sulfate) and 10,000 units bacitracin zinc, along with a propellant. each 1-second spray delivers approximately 2300 units of polymyxin b sulfate and 115 units of bacitracin zinc. this study was designed to evaluate the efficacy of polysporin spray against various clinical isolates. blood agar plates were inoculated with a pure culture of eac ...19912050717
antibacterial activity of crotalid venoms against oral snake flora and other clinical bacteria.despite heavy oral and fang contamination of crotalid species with a wide variety of potentially pathogenic bacteria, crotalid envenomation is associated with a low incidence of bacterial infection. minimal inhibitory and bactericidal concentrations of venoms from three crotalid species were determined against six aerobic and eight anaerobic reference and oral crotalid microorganisms. all anaerobic isolates were resistant to greater than 20,480 micrograms/ml, whereas variable activity (range, 5- ...19912056205
recognition of morganella subspecies, with proposal of morganella morganii subsp. morganii subsp. nov. and morganella morganii subsp. sibonii subsp. nov.the genus name morganella was established within the family enterobacteriaceae in 1978. morganella morganii is the only species described thus far within this genus, and the name m. morganii has been accepted by usage in the scientific community for strains previously known as proteus morganii. m. morganii isolates differ in their abilities to ferment trehalose and exhibit variable lysine and ornithine decarboxylase patterns, emphasizing the phenotypic heterogeneity within this species. previous ...19921390112
comparative in vitro activity and beta-lactamase stability of ru29246, the active metabolite of hr916b.hr 916b is a new orally absorbed cephalosporin. in tests its active metabolite, ru29246, inhibited streptococcus pyogenes, streptococcus agalactiae and streptococcus pneumoniae at less than or equal to 0.12 micrograms/ml, which is similar to the antibacterial activity of cefuroxime, and was more active than cefaclor. it was also more active (mic 2 micrograms/ml) than cefixime, cefuroxime, cefaclor and cefotaxime against staphylococci. ru29246 inhibited escherichia coli, klebsiella pneumoniae, ci ...19921396779
in vitro activity and susceptibility to hydrolysis of s-1006.the in vitro activity of s-1006, the active component of a new orally absorbed cephalosporin, s-1108, inhibited 90% of staphylococcus aureus isolates at less than or equal to 2 micrograms/ml, 90% of group a, b, c, f, and g streptococci and streptococcus pneumoniae isolates at less than or equal to 0.12 microgram/ml, and all haemophilus influenzae isolates at less than or equal to 0.06 microgram/ml. although 50% of the members of the family enterobacteriaceae were inhibited by less than or equal ...19921416835
cefdinir (fk482), an orally administered cephalosporin in vitro activity comparison against recent clinical isolates from five medical centers and determination of mic quality control guidelines.cefdinir, a new oral cephalosporin, was compared to cefaclor, cefadroxil, cefixime, and cefuroxime against greater than 5000 recent aerobic clinical isolates. this multicenter study revealed broad-spectrum cefdinir activity against all enterobacteriaceae (mic50s, 0.06-2 micrograms/ml) except enterobacter cloacae, morganella morganii, proteus vulgaris, and serratia marcescens (mic50s, greater than or equal to 4 micrograms/ml). oxacillin-susceptible staphylococci (mic90s, 0.5-2 micrograms/ml), bet ...19921424507
[antibacterial activities of sisomicin against fresh clinical isolates].to investigate antibacterial activities of sisomicin (siso), mics of siso as well as other aminoglycosides (ags) were determined against many clinical isolates which were obtained in 1991. results are summarized below: 1. no siso-resistant strains were observed among isolates of escherichia coli, citrobacter diversus, klebsiella pneumoniae, klebsiella oxytoca, enterobacter aerogenes, proteus mirabilis and morganella morganii. 2. in comparison with the results of our previous study against isolat ...19921433905
analysis of polar lipids from some representative enterobacteria, plesiomonas and acinetobacter by fast atom bombardment-mass spectrometry.fast atom bombardment-mass spectrometry (fab-ms) was used to analyse lipid extracts of bacteria to assess its usefulness for analysing anionic phospholipids of potential chemotaxonomic value. the following micro-organisms were tested: acinetobacter calcoaceticus, acinetobacter sp., citrobacter freundii, enterobacter cloacae (2 strains), escherichia coli (3 strains), hafnia alvei, klebsiella oxytoca, klebsiella pneumoniae, morganella morganii, plesiomonas shigelloides, proteus mirabilis (3 strain ...19921447059
[basic and clinical study of meropenem in pediatric field].meropenem (mepm), a novel parenteral carbapenem antibiotic, was examined in a cooperative study involving 12 pediatric and 1 neonatologic facilities. the results are summarized as follows. 1. antibacterial activity antibacterial activity of mepm against stock organisms including 31 strains of streptococcus agalactiae, 14 of listeria monocytogenes, 4 of bordetella pertussis and 3 of neisseria meningitidis ranged from 0.025 to 0.10 micrograms/ml in mic90's, which were equal or lower than those of ...19921479687
in vitro activity of ru 29246, the active compound of the cephalosporin prodrug ester hr 916.the in vitro activity of ru 29246 was compared with those of other agents against 536 recent clinical isolates. the mics of ru 29246 for 90% of members of the family enterobacteriaceae tested (mic90s) were less than 2 micrograms/ml except those for morganella spp. (16 micrograms/ml) and proteus spp. (8 micrograms/ml). ru 29246 was active against staphylococcus aureus (mic90, < or = 8 micrograms/ml) and against staphylococcus saprophyticus and coagulase-negative staphylococci (mic90s, < or = 2 mi ...19921489178
survey of the prevalence of beta-lactamases amongst 1000 gram-negative bacilli isolated consecutively at the royal london hospital.beta-lactamase expression was examined in 1000 consecutive gram-negative bacilli isolated from urine, wound swab, sputum or blood specimens received at the microbiology laboratory of the royal london hospital. this survey, performed between january and april, 1991, followed a similar study undertaken in early 1982. the distribution of species was similar in the two surveys, except that the proportion of pseudomonas aeruginosa isolates had increased from 11% in 1982 to 17.5% in the present study. ...19921490917
[antimicrobial activities of ceftazidime on fresh clinical isolates].antimicrobial activity of ceftazidime (caz) was compared with those of other cephem antibiotics against clinically isolated strains sent to us by medical institutions throughout japan in 1989 and 1991. those strains separated and identified from samples collected from patients with various infections were also examined, and the following results were obtained. 1. the results suggested that, compared with reports of studies conducted with clinical isolates in early 1980's, mic90 of caz in 1991 we ...19921494227
[synergistic action of cefodizime with other antimicrobial agents on clinically isolated microorganisms. ii. synergistic action with sisomicin].cefodizime (cdzm) possesses a broad antimicrobial spectrum and a relatively long half life in the blood. in addition, it shows excellent therapeutic efficacies in the treatment of infections in leukopenic animal models, hence it is expected that cdzm may have good efficacies against various infections in immunocompromised hosts. in the meantime, sisomicin (siso) not only has strong antibacterial activities against gram-negative rods (gnr), but has relatively low nephrotoxicity and ototoxicity. t ...19921495193
in vitro activity and beta-lactamase stability of ljc 10,627.the in vitro activity of ljc 10,627, a new carbapenem, was compared with those of imipenem, cefotaxime, ceftazidime, and gentamicin. ljc 10,627 inhibited 90% of escherichia coli, klebsiella pneumoniae, klebsiella oxytoca, enterobacter aerogenes, enterobacter agglomerans, enterobacter cloacae, hafnia alvei, citrobacter freundii, citrobacter diversus, proteus mirabilis, morganella morganii, proteus rettgeri, serratia marcescens, pseudomonas cepacia, salmonellae, shigellae, aeromonas, and yersiniae ...19921510436
[antimicrobial activities of ceftriaxone against clinically isolated strains].antibiotic activities (mics) of ceftriaxone (ctrx) against 1,210 strains of bacteria including 28 spp. isolated in 1987 and 1990 were compared with those of other cephems. 1. when compared to data on clinically isolated strains reported in the early 1980s, strains of the following species isolated in 1990 showed extremely elevated mic90s of ctrx: staphylococcus spp., streptococcus pneumoniae, escherichia coli, citrobacter spp., enterobacter spp., serratia spp., proteus vulgaris, morganella morga ...19921522669
in vitro activity of cefodizime.cefodizime is a bactericidal cephem with the typical broad spectrum activity of an aminothiazolyl cephalosporin, including both gram-positive and gram-negative bacteria: its mic90 is 0.125 mg/l for streptococcus pneumoniae, streptococcus pyogenes and other streptococci; and 0.05 mg/l for haemophilus spp., neisseria meningitidis, neisseria gonorrhoeae and moraxella catarrhalis; while beta-lactamase positive strains of m. catarrhalis require 1 mg/l. less than 1 mg/l is needed for escherichia coli, ...19921526673
in vitro activity of cefquinome, a new cephalosporin, compared with other cephalosporin antibiotics.the in vitro activity of cefquinome, a new aminothiazolyl cephalosporin with a c-3 bicyclic pyridinium group, was compared with ceftazidime, cefpirome, and cefepime. cefquinome inhibited members of the enterobacteriaceae at less than or equal to 0.5 microgram/ml for escherichia coli, klebsiella pneumoniae, k. oxytoca, citrobacter diversus, salmonella shigella, proteus mirabilis, morganella, and providencia. although most citrobacter freundii and enterobacter cloacae were inhibited by less than 2 ...19921611848
purification of recombinant helicobacter pylori urease apoenzyme encoded by urea and ureb.helicobacter pylori, a gram-negative, microaerophilic, spiral-shaped bacterium, is an etiologic agent of human gastritis and peptic ulceration and is highly restricted to the gastric mucosa of humans. urease, synthesized at up to 6% of the soluble cell protein, hydrolyzes urea, thereby releasing ammonia, which may neutralize acid, allowing survival of the bacterium and initial colonization of the gastric mucosa. the urease protein is encoded by two subunit genes, urea and ureb; however, accessor ...19921612735
a rare case of chorioamnionitis by morganella morganii complicated by septicemia and adult respiratory distress syndrome.morganella morganii, a gram-negative bacterium, usually infects older patients with urinary catheters, but does not commonly affect pregnant women. in this report we present a case of chorioamnionitis caused by morganella morganii. the case was complicated by a life-threatening adult respiratory distress syndrome.19921618364
reliability of a bioluminescence atp assay for detection of bacteria.the reliability of bioluminescence assays which employ the luciferin-luciferase atp-dependent reaction to evaluate bacterial counts was studied, both in vitro and on urine specimens. bioluminescence and cultural results for the most common urinary tract pathogens were analyzed. furthermore, the influence of the culture medium, of the assaying method, and of the phase of growth on bioluminescence readings was studied. results show that proteus, providencia, and morganella strains are not correctl ...19921629329
[the antigenic relationships of morganella].interspecies relationships in the genus morganella have been studied in the agglutination and adsorption tests. new data on the antigenic relationships of o groups o43 and o49 and more precise data on the antigenic relationships of o groups o1 to o42 have been obtained. for the first time the relationships of antigens 40 and 42 with 4, 35 and 31, 38 and 39, 9 and 45, 1a, d and 49; 45 and 47, 24 and 45; 5, 23, 26 with 47; 1, 19, 46 with 41, 48 have been described and the complete identity of o an ...19921281595
detection of ciprofloxacin resistance in gram-negative bacteria due to alterations in gyra.two plasmids containing the cloned escherichia coli wild-type gyra gene were used to transform ciprofloxacin-resistant gram-negative clinical isolates to screen for dna gyrase a-mediated quinolone resistance. the results show that the technique is simple and applicable to a wide range of gram-negative species including e. coli, enterobacter cloacae, klebsiella aerogenes, morganella morganii, proteus mirabilis, pseudomonas aeruginosa, campylobacter jejuni and neisseria gonorrhoeae. the use of an ...19921310671
modified macconkey medium which allows simple and reliable identification of providencia stuartii.this work describes a modified macconkey medium (mcp medium) enabling the simple identification of providencia stuartii, an emerging nosocomial pathogen. a total of 813 strains, belonging to the families enterobacteriaceae and pseudomonadaceae, were tested on mcp medium; all p. stuartii strains were phosphatase positive, as were 97.5% of morganella morganii strains, in contrast with all other tested organisms. a simple discriminating test, such as the ornithine or citrate test, allowed identific ...19921323575
susceptibility of recent clinical isolates to temafloxacin (a-63004) and other antimicrobial agents.in vitro susceptibility of 1008 strains of recent clinical isolates was determined against the new aryl fluoroquinolone temafloxacin (t-167, a-63004) ciprofloxacin, norfloxacin, ampicillin, piperacillin, cephalothin, cefoxitin, ceftazidime, gentamicin, amikacin, oxacillin and vancomycin. the minimum inhibitory concentrations (mics) of temafloxacin in micrograms/ml required for > or = 90% isolates were 0.13-0.5 for enterobacter, 0.03-0.25 for escherichia coli, 0.12-0.5 for klebsiella, 0.5-1.0 for ...19921338041
horizontal transfer of a phosphatase gene as evidence for mosaic structure of the salmonella genome.the genomes of escherichia coli and salmonella typhimurium are similar with respect to base composition, chromosome size, and the order, orientation and spacing of genes, but differ with respect to some 29 'loops', regions unique to one species. to evaluate the genetic basis for the structure and organization of the enteric bacterial genomes, we examined the gene encoding a non-specific acid phosphatase (phon) which maps to a loop at 96 min on the s.typhimurium chromosome. we detected atypical b ...19921339343
epidemiological role of arthropods detectable in health facilities.a total of 161 arthropod specimens were collected from 55 sites in a health care facility during july and september 1990. of the 116 bacterial isolates obtained from their body surfaces 6% were from parasites (mosquitoes), 59% from eusynanthropic arthropods (tenebrionid beetles, flies, german cockroaches, wasps), 16% from hemisynanthropic arthropods (ants, spiders) and 19% from occasionally encountered insects (non-biting midges, moths, beetles). most (88%) of the isolated bacteria were gram-neg ...19921350604
[occurrence of p.fimbrii in strains from selected genera of enterobacteriaceae].this study was aimed at recognition of frequency of occurrence of p fimbriae in strains of escherichia coli isolated from samples of feces of children with symptoms of diarrhoea and at search of these adhesions in strains representing other than escherichia genera of enterobacteriaceae strains. one hundred forty laboratory strains were investigated. they belonged to genus citrobacter, enterobacter, hafnia, klebsiella, morganella, proteus, providencia, salmonella, shigella, and yersinia. also wer ...19921363960
the current and future impact of antimicrobial resistance among nosocomial bacterial pathogens.the selection of drug-resistant microorganisms has generally been associated with the widespread use of antimicrobial agents. the emergence of these antimicrobial resistance has an undesirable impact that often severely limits the use of these drugs that could have otherwise been identified as "drugs of first choice." among the most serious drug-resistance problems, the chromosomally mediated type -i beta-lactamase mechanism has become more common among the infecting gram-negative bacteria. type ...19921737440
compositional analysis of peptidoglycan by high-performance anion-exchange chromatography.a high-performance anion-exchange chromatography method with pulsed-amperometric detection has been developed for the simultaneous analysis of both amino acids and amino sugars and applied to the compositional analysis of peptidoglycan hydrolysates. chromatography of the acid hydrolysis products was performed on a carbopac pa-1 anion-exchange column, with pulsed-amperometric detection. complete resolution of the two amino sugars (glucosamine and muramic acid) and eight of the nine amino acids (a ...19938214575
multicentre survey of the comparative in-vitro activity of piperacillin/tazobactam against bacteria from hospitalized patients in the british isles.twenty-nine british and irish hospitals each collected up to 300 bacterial isolates from in-patients. the organisms were identified by an appropriate api system or, for staphylococci, by their gram and coagulase reactions. disc susceptibility tests were performed. isolates that gave zones < or = 25 mm to piperacillin/tazobactam (75 micrograms + 10 micrograms) discs were sent to a central laboratory for re-examination and determination of mic, together with a sample of the more susceptible organi ...19938226427
[susceptibility in vitro to certain quinolines of gram-negative bacteria and gram-positive cocci causing urinary tract infections].susceptibility to norfloxacin, ofloxacin, pipemidic acid and nalidixic acid of 848 bacterial strains isolated from urine of patients treated in 1989-1992 in wrocław hospitals was investigated. the study, performed by the disc diffusion methods, concerned 568 enterobacteriaceae strains, 147 gram-negative non-fermenting bacteria and 133 strains of staphylococci. highest percentage (90-100%) of susceptibility to all used antimicrobial agents was detected among escherichia, proteus, morganella and c ...19938231429
study of enterobacteriaceae throughout the manufacturing and ripening of hard goats' cheese.the evolution of the counts and the species of enterobacteriaceae as well as some physico-chemical parameters (ph, aw and nacl and moisture contents) during manufacturing and ripening of a hard spanish goats' cheese of the armada-sobado variety were studied. enterobacteriaceae (mean log counts 4.45 g-1 in milk) increased 0.71-2.18 log units in curd and afterwards decreased until they disappeared after 2-4 weeks of ripening. this premature disappearance seems to be due to the decrease in aw value ...19938244902
interpretive accuracy of the disk diffusion method for testing newer orally administered cephalosporins against morganella morganii.eight newer orally administered cephems (cefdinir, cefetamet, cefixime, cefpodoxime, cefprozil, ceftibuten, cefuroxime, and loracarbef) were tested against 100 clinical strains of morganella morganii to determine the extent of serious interpretive very major (false-susceptible) errors when current criteria for the disk diffusion test are applied. agar dilution mics and disk diffusion tests were performed as recommended by the national committee for clinical laboratory standards (villanova, pa.) ...19938253998
[antimicrobial activity of cefodizime against fresh clinical isolates].in order evaluate antimicrobial activities of cefodizime (cdzm), minimum inhibitory concentrations (mic's) of cdzm and other control drugs were determined against various clinical isolates, that were sent to our center from nation-wide medical institutions or were isolated and identified in our laboratory from various specimens of infected patients. the followings are a summary of the results: 1. bacterial species with no or few strains resistant to cephems including cdzm included streptococcus ...19938254888
[the antimicrobial activity of cefteram against recently clinically detected and isolated strains].in order to examine antibiotic activities of cefteram (cftm), its minimum inhibitory concentrations (mic's) and those of other cephem drugs were determined against clinically isolated strains received from july 1990 to june 1991 and from july 1992 to february 1993 from medical facilities throughout the country and against clinically isolated strains detected in our laboratory in samples from patients with various infectious diseases. the obtained results are summarized below. 1. no cftm-resistan ...19938254900
identification and typing of proteus penneri and proteus vulgaris biogroups 2 and 3, from clinical sources, by computerized analysis of electrophoretic protein patterns.seventy-six strains of the proteus vulgaris complex (pr. penneri and pr. vulgaris biogroups 2 and 3) were characterized by one-dimensional sds-page of cellular proteins. the protein patterns were highly reproducible. the strains came from various countries and were mainly of human origin: urine (28), respiratory tract (13), wounds (8), faeces (7), blood (3), miscellaneous sources (6) and unknown sources (11). the patterns of these strains, together with those of the type strains of seven morgane ...19938300450
[report of three cases of purple urine bag syndrome which occurred with a combination of both e. coli and m. morganii].purple urine bag syndrome is a rare phenomenon in which bags turns purple or blue following catheterization. this phenomenon was reported to occur by providencia stuartii in the presence of indicanuria. we reported herein three females above 75 years of age having a similar phenomenon. all were bedridden chronically and constipated. in these cases, no growth of p. stuartii was found on repeated urine culture, but escherichia coli and morganella morganii were concomitantly isolated during the blu ...19938320467
extent of peptidoglycan o acetylation in the tribe proteeae.the degree of peptidoglycan o acetylation in 18 strains of the different genera of the tribe proteeae (proteus, providencia, and morganella) has been determined by high-performance liquid chromatography-based organic acid analysis of mild-base-released acetic acid and quantitation of peptidoglycan concentrations by simultaneous amino sugar-amino acid analysis using high-performance anion-exchange chromatography with pulsed amperometric detection. the n,o-diacetylmuramyl content of all isolated a ...19938331084
comparative in vitro activity of biapenem, a new carbapenem antibiotic.biapenem is a new carbapenem antibiotic with high stability to human renal dehydropeptidase i. its in vitro activity was compared with that of imipenem, meropenem, ceftazidime, ceftriaxone, piperacillin and gentamicin against a total of 650 recent clinical isolates. mics were determined by a standard agar dilution procedure and all isolates were tested at two inocula (10(4) and 10(6) cfu). biapenem inhibited 90% of isolates of escherichia coli, klebsiella spp., proteus mirabilis, proteus vulgari ...19938354306
[a nationwide survey of antimicrobial susceptibilities of clinical isolates to antibiotics in japan (1988-1990)].this study was conducted to investigate susceptibilities of clinical isolates to antibacterial agents at 149 hospitals throughout japan from september to december in both 1989 and 1990. in this study, identifications and susceptibility testings were carried out at each hospital laboratory. the susceptibility testings were performed according to the disk diffusion method recommended by nccls. staphylococcus aureus and coagulase-negative staphylococci showed high or moderate resistance rates to be ...19938360981
analysis of intestinal flora of a patient with congenital absence of the portal vein.a 14-year-old female patient, admitted for a closer examination of liver tumour (hepatocellular adenoma), was diagnosed as having a congenital absence of the portal vein. the blood ammonia level (approximately 120 micrograms dl-1) in the superior mesenteric vein was markedly low compared to the normal value of 300-350 micrograms dl-1 in the portal vein. the decreased ammonia concentration and urease activity of the patient's faeces were demonstrated. the dominant intestinal flora in the faeces o ...19938364525
resistance to third-generation cephalosporins in barbados.resistance to third-generation, or extended-spectrum, cephalosporins caused by induction of class i beta-lactamases has been reported rarely from developing countries. seven isolates of cephalosporin-resistant gram-negative rods were recovered recently from urine, burns and ulcers in the queen elizabeth hospital, barbados. the isolates were identified as acinetobacter calcoaceticus (2), citrobacter freundii (1), enterobacter cloacae (1), morganella morganii (1), providencia stuartii (1) and prot ...19938367967
t lymphocyte responses to antigens of gram-negative bacteria in pyelonephritis.we showed previously that large numbers of t lymphocytes accumulate within a few days in the kidneys of rats with ascending pyelonephritis induced with escherichia coli or pseudomonas aeruginosa. cd4+ t cells propagated from the lesions exhibited mhc-restricted proliferative responses to formalin-fixed bacteria of the species used to induce infection. in the present study we investigated further the nature of the antigens responsible for the t cell proliferation and studied the ability of differ ...19938403542
determinants of the activity of beta-lactamase inhibitor combinations.inhibitor combinations provide one strategy to overcome beta-lactamase-mediated resistance. their success depends, obviously, on the inhibitor being able to bind and inactivate the beta-lactamase molecules. clavulanate, sulbactam and tazobactam are irreversible inactivators of many beta-lactamases, forming covalent complexes which resist hydrolysis. 'suicide' kinetics are seen with some, but not all, enzymes. all three compounds inactivate staphylococcal penicillinase, the chromosomal beta-lacta ...19938449836
alpha-keto acids are novel siderophores in the genera proteus, providencia, and morganella and are produced by amino acid deaminases.growth promotion and iron transport studies revealed that certain alpha-keto acids generated by amino acid deaminases, by enterobacteria of the proteus-providencia-morganella group (of the tribe proteeae), show significant siderophore activity. their iron-binding properties were confirmed by the chrome azurol s assay and uv spectra. these compounds form ligand-to-metal charge transfer bands in the range of 400 to 500 nm. additional absorption bands of the enolized ligands at 500 to 700 nm are re ...19938478334
the activity of cefpirome and ten other antibacterial agents against 2858 clinical isolates collected from 20 centres.two thousand eight hundred and fifty-eight aerobic clinical isolates of enterobacteriaceae, pseudomonas species, staphylococci, streptococci and haemophilus species were collected in 19 geographically separated centres in the uk and one in ireland. the identity of each isolate was confirmed at southmead hospital and the mic of cefpirome, cefotaxime, ceftazidime, cefuroxime, cephradine, amoxycillin, piperacillin, imipenem, gentamicin, ciprofloxacin and trimethoprim was determined by an agar dilut ...19938486569
comparative antibacterial activity of the aminothiazolyl cephalosporin ru 29,246.a total of 1,007 clinical isolates from a tertiary care center were tested against ru 29,246, ampicillin, cephalothin, cefoxitin, ceftazidime, augmentin, oxacillin, piperacillin, gentamicin, amikacin and vancomycin. bacteria tested consisted of 479 strains of enterobacteriaceae, 64 pseudomonads, 18 xanthomonas, 42 other gram-negative bacilli, 56 enterococci and 348 isolates of staphylococci. ru 29,246 showed excellent in vitro activity inhibiting > 90% of escherichia coli, klebsiella pneumoniae, ...19938508687
[antimicrobial susceptibility patterns of the proteeae in japan, 1989].we discussed the antimicrobial susceptibilities of proteeae isolated in japan, 1989. eight hundred six clinical isolates were collected from 47 hospitals. these were comprised of 431 strains of proteus mirabilis, 155 proteus vulgaris, 154 morganella morganii, 44 providencia rettgeri and 22 providencia stuartii. antibiotics tested in this study were 2 penicillins, 5 cephems, 1 carbapenem and 2 aminoglycosides. the mic's were determined using the standard method of the japan society of chemotherap ...19938515560
in vitro antimicrobial activity of fluoroquinolones against clinical isolates obtained in 1989 and 1990.the in vitro activity of nine fluoroquinolones, enoxacin, norfloxacin, ofloxacin, ciprofloxacin, lomefloxacin, tosufloxacin, sparfloxacin, fleroxacin and levofloxacin, and two earlier quinolones, nalidixic acid and pipemidic acid, against 1,346 bacterial strains isolated clinically between 1989 and 1990, was evaluated by agar dilution method. the bacteria studied were staphylococcus aureus (including methicillin-susceptible and -resistant strains), staphylococcus epidermidis, enterococcus specie ...19937911351
prediction of bacterial susceptibility to cefpodoxime by using the ceftriaxone minimum inhibitory concentration result.the cross-resistance or cross-susceptibility of cefpodoxime and ceftriaxone for 3700 strains of enterobacteriaceae, oxacillin-susceptible staphylococci, streptococcus spp., haemophilus influenzae, moraxella catarrhalis, and neisseria gonorrhoeae was evaluated. with the exception of tests with enterobacter spp. and morganella morganii, the ceftriaxone minimum inhibitory concentration (mic) result interpretive criteria predicted bacterial susceptibility (or resistance) to cefpodoxime with an accep ...19938112047
[in vitro antibacterial activity of isoxazolyl++ naphthoquinones. i].the in vitro antibacterial activity of 2-hydroxy-n-(3,4-dimethyl-5-isoxazolyl) 1,4 naphthoquinone-4-imine (i) and three of this derivatives against staphylococcus aureus, escherichia coli, pseudomonas aeruginosa, proteus mirabilis y morganella morganii was investigated. from the four naphthoquinone-imine studied, compound i exhibited activity against s. aureus. this effect was observed even in oxygen atmosphere with 5% co2 and in the presence of human albumin. the development of drug-resistant s ...19938140244
[susceptibility of proteus, morganella and providencia strains isolated from patients with urinary tract infections on bactericidal activity of normal human serum].usefulness of the test determining bactericidal activity of normal human serum was investigated with 50 strains of proteus, morganella and providencia isolated from patients with urinary tract infections (uti) and with 50 strains isolated from feces. it was found that strains from uti were more frequently resistant to the action of normal human serum (50% resistant) in comparison with strains isolated from feces (30% resistant). strains of proteus belonging to four species were differing greatly ...19938189801
potential role of proteus-providencia-morganella species in quality deterioration of beef.proteeae isolation medium of hawkey et al. (1986) was effective for isolation and enumeration of proteus-providencia-morganella spp. from beef and beef products. on this medium colonies were brown, surrounded by a zone of clearing. in an examination of retail beef samples packaged and stored in polyvinyl chloride (pvc) film, 5% contained these bacteria in a concentration of 10(1)-10(2) cells per gram or cm(2). isolates from retail beef samples included p. vulgaris, p. alcalifaciens, p. rettgeri, ...199322061226
penetration of topically applied ciprofloxacin, norfloxacin, and ofloxacin into the aqueous humor.to determine the intraocular penetration of topically applied fluoroquinolone antibiotics into aqueous humor.19948190478
pore-formation by escherichia coli hemolysin (hlya) and other members of the rtx toxins family.escherichia coli hemolysin (hlya) is a major cause of e. coli virulence. it lyses erythrocytes by a colloid osmotic shock due to the formation of hydrophilic pores in the cell wall. the size of these channels can be estimated using osmotic protectant of increasing dimensions. to show that the formation of pores does not depend critically on the osmotic swelling we prepared resealed human erythrocyte ghosts loaded with a fluorescent marker. when attacked by hlya the internal marker was released, ...19948160187
spontaneous bacterial empyema and peritonitis caused by morganella morganii. 19948113596
comparison of the antibody responses to the 77 klebsiella capsular types in ankylosing spondylitis and various rheumatic diseases.the production of antibodies to klebsiella capsular polysaccharides was measured in sera from either hla-b27-positive (hla-b27+) or hla-b27-negative (hla-b27-) patients with classical ankylosing spondylitis (n = 54). these sera were compared with sera from patients with various rheumatic diseases (n = 82) and hla-b27+ or hla-b27- healthy individuals (n = 85). all sera were analyzed by means of an enzyme-linked immunosorbent assay specific to each of the 77 klebsiella serotypes. the sera from hla ...19947927763
evaluation of different antimicrobial agents used as selective supplements for isolation and recovery of yersinia enterocolitica.seventeen antimicrobial agents were evaluated separately or in combination for their efficiency as selective supplements in a broth medium against six different serotypes of yersinia enterocolitica and 20 selected strains of different gram-negative bacteria. irgasan (dp300, 5-chloro-2-(2,4- dichlorophenoxy) phenol) at a concentration of 4 micrograms ml-1 inhibited the growth of most gram-negative bacteria with the exceptions of aeromonas hydrophila, morganella morganii, pseudomonas aeruginosa an ...19947928783
[antibacterial activities of isepamicin against fresh clinical isolates of gram-negative bacilli].to investigate antibacterial activities of isepamicin (isp), mics of isp as well as other aminoglycosides (ags) were determined against many strains of gram-negative bacilli that were clinically isolated in 1993. 1. no isp-resistant strains were observed among isolates of escherichia coli, citrobacter diversus, klebsiella spp., enterobacter spp. or proteus mirabilis. 2. isp-resistant strains were observed among isolates of citrobacter freundii, serratia spp., proteus vulgaris, morganella morgani ...19947933534
[multicenter evaluation of oral antibiotics: resistance behavior in 5 swiss centers].the susceptibility of 2196 fresh clinical isolates to twelve different oral compounds was assessed in five swiss microbiology institutions during summer 1992. a standardized microdilution system including all other material necessary was employed to assess the antibacterial activity of penicillin g, ampicillin, ampicillin + sulbactam, amoxycillin + clavulanic acid, cefadroxil, cephalexin, cefaclor, cefuroxime, cefetamet, doxycycline, erythromycin and clindamycin. the aminopenicillins (including ...19947939052
microbiological studies of abscesses complicating bothrops snakebite in humans: a prospective study.forty patients with abscesses at the site of bothrops bite were evaluated. ten brought the snake responsible for the bite, bothrops jararaca in all cases. on admission a sample was collected from each case for aerobic and anaerobic culture, and no abscesses drained spontaneously. none of the patients had received antibacterial therapy at this time. the bacteria most frequently isolated were morganella morganii (23 patients), providencia rettgeri (7) enterobacter sp. (4), escherichia coli (3), gr ...19947940580
in vitro activity of cefpirome against beta-lactamase-inducible and stably derepressed enterobacteriaceae.most members of the enterobacteriaceae and pseudomonas aeruginosa possess an inducible chromosomal class i beta-lactamase. bacterial strains which produce high levels of beta-lactamase constitutively can be isolated from infections; these derepressed mutants are responsible for resistance to third-generation cephalosporins and ureidopenicillins. minimum inhibitory concentrations of cefpirome, a fourth-generation cephalosporin, and other beta-lactam antibiotics were determined for a series of mut ...19947956454
human t helper cells reactive with somatic bacterial antigens belong to the th1 subset.the aim of this study was to characterize the cytokine secretion patterns of human t helper cells from healthy donors reactive with somatic antigens from various bacteria, the nematode anisakis and tetanus toxoid. from the peripheral blood of four healthy donors we have established 70 t cell lines reactive with antigens from yersinia, salmonella, morganella, klebsiella, serratia, escherichia, chlamydia, shigella, streptococcus, tetanus toxoid and anisakis, respectively. our results show that all ...19947997190
comparative in-vitro activity of biapenem against enterobacteria with beta-lactamase-mediated antibiotic resistance.the effects of enterobacterial beta-lactamases were studied for biapenem (l627), a new carbapenem. susceptibility tests were performed for isogenic mutant series of citrobacter freundii, enterobacter cloacae, morganella morganii, serratia marcescens and proteus vulgaris which varied only in chromosomal beta-lactamase expression. beta-lactamase-derepressed organisms in these series were as susceptible as beta-lactamase-inducible strains to biapenem; beta-lactamase-basal mutants were up to eight-f ...19948040111
[antibacterial activity of aztreonam against clinical isolates].to evaluate the antibacterial activity of a monobactam antibiotic, aztreonam (azt), mics of azt and other antibiotics against clinical isolates collected at 36 participating institutions after january 1992 were determined using the agar plate dilution method (size of inoculum, 10(6) cfu/ml) according to the japan society of chemotherapy standard. the antibiotics that were tested along with azt included piperacillin (pipc), cefoperazone (cpz), and amikacin (amk). azt was found to be more active a ...19948051793
characterization and sequence of phoc, the principal phosphate-irrepressible acid phosphatase of morganella morganii.phosphatase activities were investigated in morganella morganii, which is one of the few enterobacterial species producing high-level phosphate-irrepressible acid phosphatase activity (hpap phenotype), and the gene encoding the major phosphate-irrepressible acid phosphatase was cloned, sequenced, and its product characterized. using p-nitrophenyl phosphate as substrate, morganella produced a major phosphate-irrepressible acid phosphatase (named phoc) which is associated with the hpap phenotype, ...19948081499
in vitro antibacterial activity and beta-lactamase stability of sy5555, a new oral penem antibiotic.the antibacterial activity of sy5555, a new oral penem antibiotic, was compared with those of cefaclor, cefixime, and cefteram. sy5555 was more active than the comparison agents against methicillin-susceptible staphylococcus aureus, staphylococcus epidermidis, streptococcus pneumoniae, enterococcus faecalis, citrobacter freundii, enterobacter cloacae, morganella morganii, acinetobacter calcoaceticus, clostridium spp., and bacteroides fragilis. against providencia spp., proteus spp., and haemophi ...19947811005
isolation of three hexahydro-1,3,5-trinitro-1,3,5-triazine-degrading species of the family enterobacteriaceae from nitramine explosive-contaminated soil.three species of the family enterobacteriaceae that biochemically reduced hexahydro-1,3,5-trinitro-1,3,5-triazine (rdx) and octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (hmx) were isolated from nitramine explosive-contaminated soil. two isolates, identified as morganella morganii and providencia rettgeri, completely transformed both rdx and the nitroso-rdx reduction intermediates. the third isolate, identified as citrobacter freundii, partially transformed rdx and generated high concentratio ...19947811097
in vitro antimicrobial activity of cefpirome against ceftazidime-resistant isolates from two multicenter studies.the in vitro activity of cefpirome against ceftazidime-resistant (mic > 16 mg/l) isolates from two multicenter studies was analyzed. the first investigation carried out in the usa, was an in vitro comparison of cefpirome and five third-generation cephalosporins in which more than 6,000 isolates were evaluated, including 97 enterobacteriaceae and 1,509 staphylococci resistant to ceftazidime. the second study was a multicenter international study (> 5,000 strains total) in which 160 ceftazidime-re ...19947813503
in vitro activity of cp-99,219, a novel 7-(3-azabicyclo[3.1.0]hexyl) naphthyridone antimicrobial.the in vitro activity of cp-99,219 was compared with that of ciprofloxacin and sparfloxacin against 814 clinical bacterial isolates using a microdilution method with brain-heart infusion broth. cp-99,219 was the most potent agent tested against methicillin-resistant, ciprofloxacin-susceptible staphylocci (minimum inhibitory concentration [mic]90 < or = 0.25 microgram/ml). cp-99,219 was 32-fold and fourfold more potent than ciprofloxacin and sparfloxacin, respectively, against streptococcus pneum ...19947851087
[clinical study of a new injectable cephem, fk037, for acute bacterial prostatitis].fk037, a new injectable cephem antibiotic, was administered in the treatment of 13 acute bacterial prostatitis (mean age 53.5, range 30-79), and its effectiveness and safety were evaluated. the human prostatic fluid (pf) concentration of fk037 on 7 specimens 1 hour after 1 g i.v.d., was in the range of 0.87-7.47 micrograms/ml (mean +/- sd, 3.43 +/- 2.23 micrograms/ml), whereas, the serum concentration averaged 45.3 +/- 2.88 micrograms/ml, the ratio of pf/serum consequently being 0.08 +/- 0.05. i ...19947863869
comparative in vitro activity of fk-037, a new cephalosporin antibiotic.the in vitro activity of fk-037, a novel parenteral oxime-type cephalosporin, was compared with that of cefepime, cefpirome, ceftazidime, imipenem, and gentamicin against a total of 668 recent clinical isolates. minimum inhibitory concentrations were determined by a standard agar dilution procedure, and all isolates were tested at two inocula (10(4) and 10(6) colony forming units). fk-037 inhibited 90% of isolates of escherichia coli, klebsiella species, proteus mirabilis, p. vulgaris, morganell ...19947867295
microbiological surveillance during selective decontamination of the digestive tract (sdd)the use of selective decontamination of the digestive tract (sdd) as prophylaxis against nosocomial respiratory tract infection remains controversial, largely because of concerns that, in the long term, it may promote the emergence of antibiotic-resistant strains. this report describes the results of surveillance cultures and susceptibility testing undertaken during the course of a 2-year, double-blind study of the efficacy of sdd which was conducted in a respiratory intensive care unit (icu). s ...19947868405
morganella morganii meningitis in a patient with aids. 19947884233
comparative microbiological activity and pharmacokinetics of cefprozil.in vitro studies on the activity of cefprozil have been conducted in europe and north america. against gram-negative bacilli, cefprozil and cefaclor are at least two to four times more active than cephalexin. cefixime is more active against these organisms. against gram-positive cocci, cefprozil is at least two to four times more active than cefaclor and cephalexin; cefixime has limited gram-positive activity, and is particularly inactive against staphylococci (mic90 32 mg/l). cefprozil is highl ...19947889957
pore formation in artificial membranes by the secreted hemolysins of proteus vulgaris and morganella morganii.lipid-bilayer experiments were performed with the related hemolysins from proteus vulgaris and morganella morganii (hlya). the addition of the toxins to the aqueous phase bathing lipid-bilayer membranes composed of different lipids resulted in the formation of transient ion-permeable channels. membranes formed of pure lipids were rather inactive targets for the hemolysins as compared with lipid mixtures such as asolectin. the channels had several different substrates. the major open state had si ...19947510229
commensal enteric bacteria engender a self-limiting humoral mucosal immune response while permanently colonizing the gut.we have employed a germfree mouse model to study the development and persistence of a humoral mucosal immune response to a gram-negative murine commensal organism, morganella morganii. m. morganii bacteria rapidly colonize the gut, resulting in hypertrophy of peyer's patches (pp), including germinal center reactions (gcr), and the development of specific immunoglobulin a (iga) responses detected in vitro in pp fragment cultures and by elispot assays of lamina propria cells. the gcr peaks 14 days ...19957558298
the in-vitro activity of cp 99,219, a new naphthyridone antimicrobial agent: a comparison with fluoroquinolone agents.the in-vitro activity of a new fluoroquinolone, cp 99,219 was compared with that of ciprofloxacin, du 6859, sparfloxacin and levofloxacin. cp 99,219 showed generally similar in-vitro activity to the other compounds tested against the enterobacteriaceae (mic90 of all agents < 0.5 mg/l except morganella morganii). it was found to be more active than ciprofloxacin, sparfloxacin and levofloxacin against the strains of acinetobacter calcoaceticus tested (mic90 1 mg/l). cp 99,219 was found to be four- ...19957559198
[in vitro activity of six beta-lactams against 295 strains of enterobacteriaceae and p. aeruginosa isolated from neutropenic patients].the in vitro activity of two new beta-lactam agents, cefpirome (cpo) and cefepime (fep), was investigated against 295 gram-negative bacilli (250 enterobacteriaceae and 45 p. aeruginosa) isolated from neutropenic patients. they were compared with ceftazidime (caz), piperacillin-tazobactam (tzp), imipenem (ipm) and cefotaxime (ctx). all enterobacteriacae were susceptible to ipm, 16 strains were intermediately susceptible or resistant to caz (1 strain of e. coli, 4 of morganella morganii and 11 of ...19957567110
ceftibuten: a review of antimicrobial activity, spectrum and other microbiologic features.ceftibuten is a new, orally administered cephalosporin with exceptional beta-lactamase stability and potency against commonly isolated gram-negative pathogens. more than 90% of recent enterobacteriaceae clinical isolates were inhibited by < or = 8 micrograms/ml of ceftibuten. in only five enteric species (citrobacter freundii, enterobacter aerogenes, enterobacter cloacae, morganella morganii, serratia marcescens) were more than 15% of strains resistant (minimal inhibitory concentrations (mic, wi ...19957567314
proteus mirabilis amino acid deaminase: cloning, nucleotide sequence, and characterization of aad.proteus, providencia, and morganella species produce deaminases that generate alpha-keto acids from amino acids. the alpha-keto acid products are detected by the formation of colored iron complexes, raising the possibility that the enzyme functions to secure iron for these species, which do not produce traditional siderophores. a gene encoding an amino acid deaminase of uropathogenic proteus mirabilis was identified by screening a genomic library hosted in escherichia coli dh5 alpha for amino ac ...19957592338
toc-39, a novel parenteral broad-spectrum cephalosporin with excellent activity against methicillin-resistant staphylococcus aureus.toc-39, a new parenteral cephalosporin, is a hydroxyimino-type cephem antibiotic with vinylthio-pyridyl moiety at the 3 position. toc-39 was evaluated for antibacterial activity against various clinically isolated strains. toc-39 had excellent activity, stronger than that of methicillin, oxacillin, the cephalosporins tested, imipenem, gentamicin, minocycline, tobramycin, ofloxacin, and ciprofloxacin against methicillin-resistant staphylococcus aureus (mrsa) and had an mic comparable to that of v ...19957625799
comparative antibacterial activity of l-695,256, a carbapenem active against methicillin-resistant staphylococci.the activity of a new prototype carbapenem, l-695,256, against clinical isolates of gram-positive and gram-negative aerobes was studied in vitro by agar dilution. l-695,256 was highly active against methicillin-resistant and -susceptible isolates of staphylococci (mics, 0.016 to 2 micrograms/ml) and against penicillin-resistant pneumococci (mics, 0.016 to 0.064 micrograms/ml), irrespective of penicillin susceptibility. activity against members of the family enterobacteriaceae was less than that ...19957625810
head and neck infections in pediatric cardiac transplant patients.a retrospective chart review was undertaken at columbia presbyterian medical center to assess the incidence, etiology and management of head and neck infections in pediatric cardiac transplant patients on immunosuppression. from june 1984 to february 1992, 59 cardiac transplants were performed on 57 pediatric patients. standard immunosuppressive therapy was used. thirteen of these patients died within three months of transplant and were not included. of the 44 patient charts reviewed, 82 head an ...19957628334
laboratory data which differentiate meropenem and imipenem.meropenem and imipenem are carbapenems which are distinguishable from all other currently available beta-lactam antibiotics by breadth of antibacterial spectrum and stability to beta-lactamases, but can be differentiated one from another. meropenem is relatively stable to human renal dehydropeptidase-i (dhp-i); it does not require to be co-administered with cilastatin and consequently, unlike imipenem, will be administered as a single agent. in vitro both meropenem and imipenem are active agains ...19957652504
bactericidal activity of normal human serum against morganella, proteus, and providencia strains.the susceptibility od proteus, providencia, and morganella strains to bactericidal action of human serum was examined. the percentage of survival was determined after one and three hours incubation with 50% human serum. the susceptible strains were treated by serum preparations with blocked classical or alternative complement activation pathways as well as with lysozyme removed. following mechanisms of the bactericidal action of serum were found: complement activated by the classical or alternat ...19957660859
neonatal brain abscess caused by morganella morgagni. 19957742461
[comparison of mics of new quinolones obtained using agar-dilution and broth-microdilution procedures].minimum inhibitory concentrations (mic) of new quinolones against both gram-positive and gram-negative bacteria obtained using agar-dilution and broth-microdilution procedures were compared. a primary regression curve and a correlation coefficient (r) between 2 mics for each of ofloxacin, ciprofloxacin, tosufloxacin, sparfloxacin or balofloxacin were calculated. for the 5 quinolones, average correlation coefficients were 0.891 for the gram-positive bacteria tested, and 0.865 for the gram-negativ ...19957752452
a histidine decarboxylase gene encoded by the vibrio anguillarum plasmid pjm1 is essential for virulence: histamine is a precursor in the biosynthesis of anguibactin.we have identified and sequenced an hdc gene in the vibrio anguillarum plasmid pjm1 which encodes a histidine decarboxylase enzyme and is an essential component for the biosynthesis of anguibactin. the open reading frame corresponds to a protein of 386 amino acids with a calculated molecular mass of 44,259.69 da. the amino acid sequence has extensive homology with the pyridoxal-p-dependent histidine decarboxylases of morganella morganii, klebsiella planticola, and enterobacter aerogenes. tn3-hoh ...19957752899
purification and properties of crystalline 3-methylaspartase from two facultative anaerobes, citrobacter sp. strain yg-0504 and morganella morganii strain yg-0601.3-methylaspartase (3-methylaspartate ammonia-lyase, ec 4.3.1.2) from two facultative anaerobes from soil, citrobacter sp. strain yg-0504 and morganella morganii strain yg-0601, were purified and crystallized from their crude extracts. both of the citrobacter and morganella enzymes appeared to be a dimer of subunits of m(r) 40,000 and 44,000, respectively. the enzymes had similar enzymological properties: optimum ph for the deamination reaction of (2s,3s)-3-methylaspartic acid, substrate specific ...19957765982
cloning and characterization of the napa acid phosphatase/phosphotransferase of morganella morganii: identification of a new family of bacterial acid-phosphatase-encoding genes.the gene encoding a minor phosphate-irrepressible acid phosphatase (named napa) of morganella morganii was cloned and sequenced, and its product characterized. napa is a secreted acid phosphatase composed of four 27 kda polypeptide subunits. the enzyme is active on several organic phosphate monoesters but not on diesters, and is also endowed with transphosphorylating activity from organic phosphoric acid esters to nucleosides and other compounds with free hydroxyl groups. its activity is inhibit ...19957894706
in vitro activity of subinhibitory concentrations of quinolones on urea-splitting bacteria: effect on urease activity and on cell surface hydrophobicity.the effect of subinhibitory concentrations of ciprofloxacin, lomefloxacin, norfloxacin, ofloxacin, and sparfloxacin on urease activity and on cell surface hydrophobicity of urea-splitting bacteria was examined. quinolones at 0.5 mics demonstrated variable effects on bacterial-urease activity. norfloxacin inhibited enzyme activity in proteus vulgaris and proteus mirabilis, while other quinolones had no effects. in morganella morganii, sparfloxacin and ciprofloxacin enhanced urease activity, parti ...19957844396
turkey rhinotracheitis virus isolated from broiler chicken with swollen head syndrome in japan.turkey rhinotracheitis (trt) virus was first isolated from a commercial broiler chicken with swollen head syndrome (shs) in japan. at the same time, newcastle disease virus (ndv), infectious bronchitis virus (ibv), avian reovirus (arv), escherichia coli (e.coli), morganella morganii, and proteus mirabilis were also isolated from the same broiler chicken. the presence of antibodies to trt virus was confirmed in the sera of 34-day-old chickens of the flock with shs, however the antibodies to trt v ...19958593307
the most frequently occurring aminoglycoside resistance mechanisms--combined results of surveys in eight regions of the world. the aminoglycoside resistance study groups.aminoglycoside-resistant isolates from different patients were collected in 149 hospitals in eight regions of the world. aminoglycoside resistance mechanisms were determined in 11,079 of these isolates by the correlation of resistance phenotypes to 12 aminoglycosides and dna hybridisation with up to 19 resistance genes. a very large diversity of different resistance mechanisms was found. for example, in escherichia-morganella-proteus-salmonella-shigella, at total of 53 different mechanisms was f ...19958622108
the changing nature of aminoglycoside resistance mechanisms and the role of isepamicin--a new broad-spectrum aminoglycoside. the aminoglycoside resistance study groups.aminoglycoside resistance mechanisms from recent studies were compared with those found in earlier studies in the usa and europe for three pathogen groups. among citrobacter-enterobacter-klebsiella, four single mechanisms (aac(3)-ii, aac(3)-i, ant(2")-i and aac(6')-i were found in all studies, but the most recent studies showed a significant increase in combinations of aac(6')-i with the other common mechanisms. since aac(6')-i confers resistance to tobramycin, netilmicin and amikacin, combinati ...19958622109
[clinical and laboratory significance of inducible beta-lactamases].many species of bacteria have inducible expression of beta-lactamase and the enzyme production in these bacteria is normally held at a low level by a repressor mechanism, but in the presence of a beta-lactamase inducer this repression is lifted and enzyme production is greatly increased. inducible synthesis of beta-lactamase was first described for the gram-positive organism bacillus licheniformis. after that inducible expression of beta-lactamase was discovered in gram-negative bacteria like en ...19958643019
morganella morganii pericarditis after resolvent splenectomy for immune pancytopenia following allogeneic bone marrow transplantation for acute lymphoblastic leukemia. 19958645811
in vitro activity of e-4868, a new fluoroquinolone with a 7-azetidin ring, compared with ciprofloxacin, ofloxacin and fleroxacin.e-4868, (-)-7[3-(r)-amino-2-(s)-methyl-1-azetidinyl]-1-(2,4- difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-3-quinolinecarboxylic acid, is a new fluoroquinolone with a 7-azetidin ring substituent. the in vitro activity against clinical isolates was compared with that of ciprofloxacin, ofloxacin and fleroxacin. in general, activity of e-4868 against aerobic and facultative anaerobic gram-negative bacilli was equal to or slightly less active than ciprofloxacin with the exception of morganella morganii ...19958529525
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