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isolation of plasma-membrane components from cultured human pancreatic cancer cells by immuno-affinity chromatography of anti-beta 2m sepharose 6mb.human pancreatic exocrine adenocarcinoma cells established in tissue culture expressed both hla and beta 2-microglobulin (beta 2m). plasma-membrane components of this pancreatic cancer cell line were purified from plasma membrane fractions enriched by sucrose density-gradient centrifugation, using immunoaffinity chromatography on immobilized anti-human beta 2m antibody. both rabbit and mouse monoclonal anti-beta 2m igg were used, with a 20--25-fold overall purification of 5'-nucleotidase. the me ...197992330
[5-azacytidine and new formation of purine nucleotides, rna, proteins, and lipids in the cerebral cortex of guinea pigs (author's transl)]. 197992352
ductular carcinoma of the breast: serum antibodies to tumor-associated antigens.serum antibodies to tumor-associated antigens of breast carcinoma have been studied by indirect immunofluorescence in 109 patients with breast carcinoma and 125 controls, including age/sex matched normal individuals, patients with nonmalignant disease, and patients with malignant disease other than breast cancer. we report here that sera of a large proportion of patients with ductular carcinoma of the breast have antibodies to cell surface and/or intracellular antigens of autologous tumor cells ...200092359
[clinical effects of chlormadinone acetate (cma) on human benign prostatic hypertrophy--comparative study with hexestrol by a double blind trial (author's transl)]. 197992377
cutaneous manifestations of acute carbon monoxide poisoning.a patient with acute carbon monoxide poisoning due to leakage of gas from the exhaust system in his automobile noted edema and blister formation over large areas of the skin of one half of his body. rhabdomyolysis, acute but transient renal insufficiency, and hemolytic anemia developed subsequently.200092389
serial determination of marker substances in ovarian cancer. 200092437
clinical trial of bleomycin in the treatment of gestational trophoblastic disease. 200092439
populational polymorphisms in silver staining of nucleolus organizer regions (nors) in human acrocentric chromosomes.the ag stainability of the nucleolus organizer region (nor) was studied in the acrocentric chromosomes identified by q banding of cultured lymphocytes in 41 karyotypically normal persons (33 males and 8 females) originating from southeast estonia. the data obtained are compared with those established earlier for a combined vienna-ulm population of 51 karyotypically normal persons (see mikelsaar et al., 1977a). significant differences between the two populations in the frequency and patterns of a ...197992452
nonspecific light loss and intrinsic dna variation problems associated with feulgen dna cytophotometry.nonspecific light loss by the cell-wall-plus-cytoplasm (cwc) can cause a 50% increase in feulgen absorption units in peanut root-tip nuclei as determined by scanning at 450 nm, whereas this phenomenon is not evident with chicken erythrocytes. a two wavelength scanning method of subtracting nonspecific 450 nm absorption from 550 nm feulgen absorption values eliminated the nonspecific light loss in cwc, however, the two wavelength scanning method is time consuming and somewhat impractical with a r ...197992496
ia determinants on human t-cell subsets defined by monoclonal antibody. activation stimuli required for expression.the nature of ia antigens which appear on human t cells after activation and the stimuli required for their expression was examined utilizing a monoclonal antibody reactive with the ia antigen framework. t cells were purified using monoclonal antibodies directed either at the entire t-cell population (okt3) or the t-cell inducer subset (okt4). by indirect immunofluorescence, it was shown that the human t-cell population contains no detectable ia+ cells in the resting state. in contrast, in exces ...197992523
right/left differences of median nerve evoked scalp potentials in multiple sclerosis.scalp potentials evoked by electrical stimulation of the median nerve at the wrist were examined in multiple sclerosis patients and healthy controls. the latencies of the first negative peak (about 18 ms latency) of the response to right and to left-sided stimulation were compared. forty-eight of 60 measured latency differences in 15 suspected or certain ms patients were more than 3 standard deviations beyond the average difference in controls (arbitrary norm limit), whereas none of the 56 resul ...200192533
isotachophoresis of csf proteins in gel tubes especially gammaglobulins. an analytical and preparative technique for high-separation of csf proteins.an isotachophoretic method using polyacrylamide gel (pag-itp) in a simple disc electrophoretic equipment with plastic tubes containing the gels, was elaborated and especially designed for studying the gammaglobulins in csf and serum from control subjects and patients with neurological disorders, especially known or probable ms. the device and the itp system used, including leading and terminating electrolytes and spacer substances, dividing the gammaglobulins in a reproducible way, are described ...200192548
intrathecal igg synthesis in multiple sclerosis and other neurological diseases: a comparative evaluation by igg-index and isoelectric focusing.intrathecal igg synthesis has been investigated by determining the igg index and by isoelectric focusing in 30 cases of definite multiple sclerosis, in 15 cases of probable multiple sclerosis and in 128 patients affected by other neurological diseases. the blood-brain barrier function was evaluated at the same time by serum albumin/csf albumin quotient and isoelectric focusing. the igg index was found elevated in 73.3% of definite multiple sclerosis patients, while oligoclonal igg bands occurred ...200192550
biologically active polycycloalkanes. 6. antiviral 1-tricyclo[4.3.1.1 2,5]undecyl derivatives.functionalization reactions via cationic intermediates of tricyclo[4.3.1.1 2,5]undecane (2) were investigated to prepare derivatives with potential antiviral activities. bromination of 2 took place regiospecifically at c-1, and the resulted bromide 5 was converted into the hydroxide 9, the carboxylic acid 12, and the amine 22, from which were synthesized a variety of secondary derivatives, including homologous esters 10 and 20, amides 14 and 19, carbamates 24, and ureas 17 and 25. the hydroxide ...197992566
[method of differentiating k. ozaenae and k. rhinoscleromatis by means of a biotest]. 197992603
ulcers, heart disease, and type-a behaviour. 200192641
olivocerebellar projections in the cat studied by means of anterograde axonal transport of labelled amino acids as tracers. 197992769
[nursing care of cancer patients]. 200192813
tuberculosis. clinical aspects and diagnosis.the presentation of tuberculosis is variable depending on the severity of the infection, the age of the patient, whether the infection is primary or secondary, and whether the manifestations are due to inhalation of organisms or hematogenous dissemination. a definitive diagnosis is made by culture of the organism; spontaneously expectorated sputum is the most suitable specimen for diagnosing pulmonary tuberculosis. diagnosis of extrapulmonary tuberculosis frequently requires tissue biopsy. the c ...200192919
intracellular ph transients induced by chloride substitution in cardiac purkyne fibres [proceedings]. 197992940
immunological heterogeneity of the subunits of limulus polyhemus haemocyanin [proceedings]. 200192962
isolation and cell culture propagation of rotaviruses from turkeys and chickens.rotaviruses were detected by electron microscopy in the faeces of turkey poults and broiler chickens with diarrhoea. apparently symptomless infection was also observed in broilers. the avian rotaviruses could not be isolated in cell cultures by conventional techniques, but were adapted to serial growth in chick cell cultures following trypsin treatment of the virus and the cells. immunofluorescence studies showed that the avian and mammalian rotaviruses are antigenically related. antibodies to r ...197992979
selective aromatic-hydrophobic binding and fractionation of immunoglobulin by means of phenyl-(ch2)n-nh-substituted agaroses. 197992988
abolition of non-specific fluorescent staining of labrocytes (mast cells) with protamine sulfate. 200193022
presence of human milk particle--specific antigens in malignant human breast tumor tissues. 197993088
quantitative succinate-dehydrogenase histochemistry. i. a methodological study on mammalian and fish muscle.in enzyme histochemistry formazan production can be used as a measure for oxidative enzyme activity. the formazan deposits can be measured quantitatively per cell with a scanning and integrating microspectrophotometer. optimal conditions are described for the estimation of histochemical succinate dehydrogenase activity in sections of fish bodymusculature and mouse soleus and plantaris muscle. it is shown that when proper measuring conditions are chosen a ditetrazolium salt (tnbt) can be used in ...197993099
an exploration of a patient-centred nursing approach in the admission of selected surgical patients: a replicated study.it is well recognized that admission to hospital is a stressful experience for patients, and little attention is directed towards helping patients to adapt to hospitalization. this paper reports the replication of a descriptive study which explored the patient's welfare after the use of a patient-centred nursing approach designed to alleviate stress on admission to hospital. it also attempts to determine the patient's perception of the nurse during the implementation of the admission procedure, ...200193119
immunological relationships among ovine glycoprotein hormones.an antiserum to partially purified ovine fsh (but essentially free of lh) bound 125i-labelled ovine lh or bovine tsh. the antibody was directed exclusively against determinants in the alpha subunit. in a radioimmunoassay, only the intact ovine and bovine hormones and their alpha subunits were reactive; the hormone specific beta subunits exhibited no cross-reaction. the antibody directed against the alpha subunit was highly dependent on conformation. human lh, fsh, tsh or their alpha subunits did ...197993139
specificity of serovar-specific main antigens of leptospiras shown by the inhibition of leptospiral microscopic agglutination. 197993155
[determination of human blood protein phenotypes]. 197993164
hazards of intravenous diazoxide. 200193203
perinatal mortality. 200193220
[clinical aspects, diagnosis and treatment of cancer of the large intestine]. 200193232
spinal subdural hematoma: case report and review of the literature.a case of lumbar spinal subdural hematoma in a patient who had been on anticoagulant therapy is reported. thus far 19 cases of spinal subdural hematoma have been reported in the literature, the majority in patients with a bleeding diathesis and after a lumbar puncture. our case is the third reported to be in association with anticoagulant therapy. the hematoma was lumbosacral, in contrast to the usual location in the dorsal-lumbar area. a possible mechanism for the production of spinal subdural ...200193254
serum beta2-microglobulin in liver disease.the concentration of beta 2-microglobulin in serum was determined in seventy-one patients with various liver disorders. elevated values were found in most patients with chronic active or chronic persistent hepatitis and in over 80% of patients with alcohol-induced liver cirrhosis. in contrast, patients with alcohol-induced fatty liver, the serum beta 2-microglobulin concentrations were mostly within the normal range. significant correlation (p less than 0.001) was noted between the elimination r ...200193302
visualization of subsurface structures in cells and tissues by backscattered electron imaging.a fraction of the beam electrons which interact with a specimen scatter back. the number of backscattered electrons (be's) increases with the atomic number of the elements encountered. cell and tissue structures lacking a heavy metal content yield few be's compared to structures affixed with heavy metals, either vitally or by means of staining methods applied after fixation. the be imaging mode of a scanning electron microscope (sem) provides an intensity map of the be yield from the specimen. b ...197993305
studies on plasma inhibitors of plasma kallikrein using chromogenic peptide substrate assays. 200193313
[monoreceptor sera to the antigenic determinants of influenza virus a hemagglutinin].the method of specific adsorption was used to produce monoreceptor sera to individual antigenic determinants of hemagglutinin of influenza a virus, hong kong variant. the sera were completely free of inhibitors, contained no antibody to neuraminidase or host cell antigens. the monoreceptor sera were used in hi tests and immunoelectrophoresis for the qualitative and quantitative analysis of the antigenic variants isolated in 1968--1977. it was shown that alongside with the appearance of qualitati ...197993350
quantitation of skin bacteria: lethality of the wash solution used to remove bacteria.a widely used technique for the quantitative removal of bacteria from the skin uses a detergent, triton x-100 (p, t-octylphenoxynonaethoxyethanol), to remove and suspend the bacteria. we determined the half-life for the survival of five common skin bacteria suspended in the solution. the shortest-lived was streptococcus pyogenes with a half-life of 0.9 hours. all of the others (propionibacterium acnes, staphylococcus epidermidis, staphylococcus aureus, and klebsiella pneumoniae) had half-lives o ...197993373
a neuropathologic study of whipple's disease.a patient with whipple's disease developed massive and irreversible cns involvement after a drug-induced intestinal remission. the multifocal brain lesions were apparent grossly with the heaviest concentration being noted in rhinencephalon, diencephalon, and mesencephalon. this patient exhibited progressive neurologic deterioration, although viable organisms could not be identified in the brain at autopsy. astrocytes, pericytes, and choroid plexus cells attempted to dispose of the organism, in a ...199993389
viruses and human cancer. a puzzle with a few missing pieces. 197993407
home observation for measurement of the environment: a revision of the preschool scale.information pertaining to a revision of the caldwell home inventory for use with families of children ages 3 to 6 was presented. factor and item analyses were used as a basis for reducing the number of items from 80 to 55. the items were clustered into eight subscales. kuder-richardson 20 coefficients for the scale ranged from .53 to .93. concurrent and predictive validity studies indicated that the home scales significantly correlated with iq (as high as r = .58). low to moderate correlations w ...199993417
direct visualization of collagens and procollagens in polyacrylamide gels. 197993420
in vitro production of rauscher murine leukemia virus: influence of culture age on biological properties.large-scale production and concentration procedures have been standardized to study the biological properties of rauscher leukemia virus produced from the high-passaged jls-v9-h mouse bone marrow cell line. virus produced early (days 4 to 6) in the harvest and refeed cycle contained higher levels of ribonucleic acid-directed deoxyribonucleic acid polymerase activity and was more infectious than rauscher leukemia virus produced later (days 7 to 10) in the growth period. the peak of virus producti ...197993428
[effect of the modality of exercise on the vo2 max].1. maximum oxygen consumption has been measured by means of three different exercises: cycle ergometry, treadmill running and uphill walking with a 20 kg-load. 2. loaded walking allowed to reach a vo2 max level in average 2% greater than running and 13% greater than bicycling. 3. this finding suggest that vo2 max may depend on peripheral factors.199993446
[cis expression, at complementation, of mitochondrial mosaic gene exons regulating cytochrome b in saccharomyces cerevisiae (proceedings)]. 197993454
a novel class of schizosaccharomyces pombe mutants, phenotypically unable to grow on glycerol, a respiratory substrate, but still able to oxidize glycerol aerobically [proceedings]. 197993469
[cerebrospinal fluid monoamine metabolites and cyclic nucleotides in the patients with epilepsy (author's transl)]. 199993481
sickle cell trait and diabetic retinopathy.the presence of sickle cell trait and the prevalence and severity of retinopathy were assessed in 124 negro diabetics. sickle cell trait had no adverse effect on diabetic retinopathy.199993492
pineal vasotocin and sleep: involvement of serotonin containing neurons. 197993502
acute lindane poisoning. 199993506
pharmacokinetics of tallysomycin and bleomycin in the beagle dog.the pharmacokinetics of tallysomycin, a third-generation bleomycin analog, and bleomycin have been determined and compared in the beagle dog. both compounds exhibited biphasic plasma elimination characteristics and were extensively absorbed after in injection. the elimination half-lives of tallysomycin after iv and im administration were 1.51 +/- 0.41 hours and 2.40 +/- 0.667 hours respectively. these values were longer than the comparable iv (1.01 +/- 0.19 hours) and im (1.12 +/- 0.39 hours) el ...197993509
immunochemical studies on alcoholic hyalin. 197993559
[purification and characterization of the free secretory piece of human colostrum (author's transl)].the free secretory piece is isolated from human colostrum by gel filtration and ion-exchange chromatography in high yield (200 mg/l colostrum). deae-cellulose chromatography separates the free secretory piece in two fractions which are electrophoretically distinct, but otherwise have the same characteristics, like molecular weight, antigenic determinants, n-terminal sequence, peptide map and amino acid composition. it was therefore concluded that the protein part of the secretory piece is homoge ...197993565
the application of immunoperoxidase methodology for the visualization of prolactin binding sites in human prostate tissue.in previous studies the immunoperoxidase method was used to detect intracellular prolactin binding sites in epithelial cells of normal and neoplastic rat prostate. as an extension of this work, the same approach was used to test for and to localize prolactin binding sites in autopsy and biopsy specimens of formalin fixed, paraffin embedded human prostate. rehydrated tissue sections were exposed to varying concentrations of human placental lactogen or human prolactin and then to human placental l ...197993568
ma 160 and eb33 cell lines: hela cell contaminants, hybrids or prostatic epithelial cells?studies of acid phosphates produced by cell lines ma 160 and eb 33 demonstrated immunochemically their prostatic origin. ma 160 and eb 33, rather than being hela contaminants, may be hybrids of prostatic epithelial and hela cells or true prostatic cell lines with chromosomal changes common to all long-term cultivated cell lines.199993571
alpha-fetoprotein inhibits antibody binding to acetylcholine receptor. significance for myasthenia gravis and other autoimmune diseases. 197993589
a multidisciplinary therapeutic approach for advanced previously untreated epidermoid cancer of the head and neck: preliminary report. 199993595
chlorpyrifos and 3,5,6,-trichloro-2-pyridinol: residues in the body tissues of cattle wearing chlorpyrifos-impregnated plastic ear tags. 197993609
the prognosis of intraventricular hemorrhage.a series of 40 patients with blood in the cerebral ventricular system demonstrated by computed tomography (ct) is presented. overall prognosis was found to be better than expected from the literature. nearly half of the patients are still alive; 12 of the 40 patients in this study had no significant residual disability. the results suggest that the rupture into the ventricular system by itself is of minor importance. however the clinical condition of the patient on admission, site and origin of ...199993626
differentiation of normal pressure hydrocephalus and cerebral atrophy by computed tomography and spinal infusion test.the diagnostic value of computed tomography (ct) and spinal infusion test (sit) was investigated in 27 patients with normal pressure hydrocephalus (nph) and 35 patients with cerebral atrophy. the most consistent ct finding of nph was dilatation of the temporal horns, that of cerebral atrophy widening of the convexity sulci. however, 43% of patients with cerebral atrophy demonstrated no cortical atrophy. the sit showed an excellent relation with isotope cisternography and continuous intracranial ...199993629
the symptomatology with the most severe clinical course of spontaneous subarachnoid hemorrhage.the symptomatology of 18 patients with the severest clinical course after subarachnoid hemorrhage (sah) is described and analyzed. seventeen patients died, five with an acute bulbar syndrome with cardiac arrest, and 12 with irreversible breakdown of brain function. one patient had an apallic syndrome with minimal signs of remission, who died 4 months after the first rebleeding. the cases are divided into five clinical groups on the basis of the acute brainstem symptomatology which set in instant ...197993630
base-pairing between distant regions of the escherichia coli 16 s ribosomal rna in solution. 197993645
[radiomanometric study of the anatomic sites of the pressure profile (author's transl)].the analysis of the urethral pressure profile was realised on 30 normal patients. the technique of radiomanometry permitted to visualize the anatomic sites of the urethral and the corresponding pressure.199993650
[body surface isopotential mapping of ventricular extrasystole, with special reference to the qrs mapping during ventricular pacing]. 197993651
hepatocellular carcinoma and fetal hemoglobin. 199993665
1-isoamyl-3-isobutylxanthine: a remarkably potent agent for the potentiation of norepinephrine, histamine, and adenosine-elicited accumulations of cyclic amp in brain slices. 197993674
projection system with brightness amplifier for biology and medicine.some results of investigation of biological systems using laser projection microscope is given. the scheme permitted to work both in reflected and transmitting light. the image of a living cell on a large screen was observed.199993683
[ultrastructural changes in keratoacanthoma]. 199993699
demonstration of alpha 2-pregnancy associated-glycoprotein (alpha 2-pga) in serum of men with different localization of cancer.by counterimmunoelectrophoresis in agarose gel the presence of alpha 2-pga in the sera of 28 untreated patients with different localization of cancer was demonstrated. in 17 (60.7%) a precipitation line between the well with patient serum and that with monospecific anti-alpha 2-pga serum, diluted 1 : 7 was obtained. at 1 : 7 dilution, with the sera from 28 healthy persons precipitation lines were not obtained. the determination of alpha 2-pag can be made quickly and contributes to cancer diagnos ...199993708
[the difficulties of acquisition and development of the semiotic function of psychotic-deficient children. possibilities of treatment (author's transl)]. 199993711
a horseradish peroxidase study of primary afferent projections to the medullary cuneate nucleus in the rat.hrp was used to label first order afferent cells of the dorsal root ganglia which synapse at the cuneate nucleus. the results show that it is a population of predominantly large cells that project monosynaptically to the medullary cuneate nucleus and thus support anatomical and physiological studies showing that directly projecting axons to the dorsal column nuclei are larger, faster and conduct information from a select class of sensitive cutaneous mechanoreceptors. the finding, that approximat ...197993721
[mechanism of antibiotic action]. 199993768
[action of feeding lindane or/and zineb on aflatoxin b1-induced toxic effects in rat and mouse liver (author's transl)].the action of the ingestion of balanced diets containing pesticides [lindane (125 ppm) or/and zineb (5200 ppm)] on aflatoxin b1-induced toxic effects (inhibition of rna and protein syntheses in liver) has been determined in two animal species. in the rat, the ingestion of these diets for 4 weeks before aflatoxin b1 treatment (0,7 mg/kg for 3 h), strongly decreased the toxic effects on both transcription and translation. by contrast, in the mouse, the above-mentioned diets did not modify the exte ...197993790
identification of an hla-dr-associated system of b-cell alloantigens. 199993800
chido, rodgers, and c4 deficiency. 199993815
[the current discussion: drug treatment of pain caused by cancer]. 199993853
characterization of an antigen-specific factor from a hybrid t-cell line. 197993865
reinvestigation of denervation diuresis and natriuresis in conscious dogs.the function of innervated and denervated kidney was compared in clearance studies with conscious dogs. the animals were prepared for experiments by unilateral renal denervation and surgical division of the bladder to form two hemibladders enabling separate urine collection from two kidneys. the mean urine flow was 6% higher for the denervated kidney (not significant) while mean differences for osmolar clearance (+ 13%), sodium excretion (+21%) and gft (+5%) were all significant (p less than 0.0 ...197993884
purification of prophenoloxidase in the haemolymph of calliphora vicina (r. & d.).an improved method for the purification of prophenoloxidase is described. the proenzyme was purified 400 fold in homogenous form. the purity was tested by disc-electrophoresis and the molecular weight was found to be 87 000 in comparison to the mobility of marker enzymes, which were run simultaneously in sds-gel electrophoresis. the proenzyme was denatured at 80 degrees c and maximum conversion into active state was found between 40 and 50 degrees c.197993886
effects of exogenous gonadotropic and steroid hormones on the social behaviour and gonadal maturation of male domestic ducklings anas platyrhynchos l.male domestic ducklings were injected during their first month of life with mammalian gonadotrophins (ovine lh or fsh, hmg) or gonadal steroids (testosterone or oestradiol). lh and testosterone stimulated sexual behaviour while oestradiol inhibited the increase of aggression observed in control birds during the experiment. the mammalian gonadotrophins did not increase plasma testosterone but nevertheless they all stimulated the testis growth. several hypotheses which could explain this finding ( ...197993890
preparation and characterization of antisera to 17 beta-oestradiol and to progesterone [proceedings]. 197993905
structure of artemia salina lipovitellin [proceedings]. 199993907
mechanism of action of beta-d-xylosidase from bacillus pumilus prl b12: ph- and alpha-deuterium kinetic isotope effects [proceedings]. 197993945
precocious puberty associated with primary hypothyroidism in a mongol girl.a mongol child suffereing from hypothyroidism who presented with precocious puberty is described. a presumptive diagnosis of idiopathic precocious puberty was first made and she was treated initially with medroxyprogesterone acetate, and later, with cyproterone acetate. the diagnosis of primary hypothyroidism was made late because of misleading results of protein bound iodine estimations. subsequently, thyroid medication resulted in a prompt return to the normal range of the previously elevated ...199993994
a developmental model for studying choline acetyltransferase transport in chick motoneurons.the proximodistal axonal transport of choline acetyltransferase (chac) has been studied in the chick sciatic nerve in the absence of any experimental manipulation. the phenomenon utilized by us is a physiological transient fall in the activity of chac. this fall occurs in most areas of the chick central nervous system after hatching, and moves toward the periphery along the nerves. having ruled out the presence of transient inhibitors, the movement of the fall towards skeletal muscles has been c ...197994010
amylase/creatinine clearance ratio and tubular proteinuria in acute pancreatitis.amylase/creatinine clearance ratio (cam/ccr), urinary protein concentration and urinary protein pattern were studied in 102 samples from 27 patients with acute pancreatitis and in 46 controls. raised cam/ccr, proteinuria and a tubular protein pattern were present in 74, 56 and 96% of the patients, respectively. however, cam/ccr and proteinuria and cam/ccr and tubular protein pattern were not correlated. these results do not support the suggestion that an elevated cam/ccr in acute pancreatitis is ...199994020
a human breast tumor cell line (bt-474) that supports mouse mammary tumor virus replication.a human breast tumor cell line bt-474 derived from an invasive ductal carcinoma was experimentally infected in vitro with a mouse mammary tumor virus from the tiii strain (riii-mumtv). the virus that replicated in the human cells was characterized as a mouse virus by immunofluorescence, electron microscopy and the presence of a specific rna-directed dna polymerase. the cells themselves were human as per the karyotype and isoenzyme migration patterns. it is concluded that human cells are suscepti ...197994035
chemical, biochemical, and cellular properties of copper and iron bleomycins. 199994054
[palliative chemotherapy with 5 fu and cpm in cancer of the prostate with bone metastases resistant to oestrogens. a clinical trial (author's transl)].the efficacy of an association of cyclophosphamide (cpm) and 5-fluorouracil was studied in 15 patients with prostate cancer not responding to oestrogen therapy, and more particularly its effect on pain due to bone metastases. no objective improvement was noted with this association, but there was a definitite reduction in bone metastases pain in 5 of the patients, with an average remission time of 4 months. half of the patients had nausea and vomiting, but in spite of this digestive intolerance ...199994108
[prevention and therapy of disorders of pulmonary microcirculation]. 199994119
kallikreins (kininogenases)--a group of serine proteases with bioregulatory actions. 199994166
mixed bullous disease with labile erythrocyte sedimentation rate.a woman, aged 66, fulfilled all the usual criteria of dermatitis herpetiformis. subsequently, she developed circulating iga and igm basement membrane zone antibodies, a labile erythrocyte sedimentation rate (esr), and the clinical picture changed to one of bullous pemphigoid. her labile esr was obviously caused by a factor related to the erythrocytes. direct coombs test was positive.199994214
induction of delayed-type sensitivity to leishmania parasite in a case of leishmaniasis cutanea diffusa with bcg and cord-factor (trehalose-6-6' dimycolate).the delayed hypersensitivity against the leishmania parasite was restored to a patient who had suffered from diffuse cutaneous leishmaniasis (dcl) for 26 years, by the application of an ointment containing heat-killed and lyophilized bcg and cord-factor (trehalose-6-6'-dimycolate) after stripping the affected and adjacent areas with scotch-tape.197994221
stringent control in e. coli. 197994252
biochemical and immunological studies of three genetic variants of 3-phosphoglycerate kinase 2 from the mouse.three electrophoretic variants of 3-phosphoglycerate kinase 2 (pgk-2a,pgk-2b, and pgk-2c) were purified from dba/2j, c3h/hej, and c57l/j mice, respectively. pgk-2c exhibits only 2% of the specific activity of pgk-2a and pgk-2b in the reaction leading to the formation of 1,3-diphosphoglycerate. compared to pgk-2a and pgk-2b, pgk-2c exhibits broader coenzyme specificity and lower kms for substrate and coenzymes. incubation at 45c revealed immunionactivation and double immunodiffusion studies show ...197994263
[molecular mechanism of action of diamidinephenylindole (dapi). ii. effect of dapi on the template activity of dna and polydeoxynucleotides in the dna-polymerase system from bacteria, eukaryotic cells and rna tumor viruses (author's transl)]. 197994275
[clinical trial of a new locally acting product in acute venous inflammation]. 200094278
serum isoamylases in diseases of the lung and control subjects of thermolabile serum amylase component. 200094301
[improvement of blood viscosity after infusion of low-molecular hydroxyethyl starch (expafusin) in healthy subjects].in healthy volunteers, 500 ml of a 6% low molecular weight hydroxyethyl starch solution (expafusin) was infused intravenously within 30 minutes. blood samples for the measurement of rheological parameters were obtained before and after the infusion. blood and plasma viscosity were significantly decreased after the infusion of hes. red cell deformability as measured by a filtration technique was slightly improved. red cell aggregation as measured by a light transmission method was markedly reduce ...200094316
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