Publications

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the sensitive period and malformation syndrome produced by thalidomide in crab-eating monkey (macaca fascicularis). 19734207404
vascular heterograft: human umbilical cord vein as an aortic substitute in baboon. a preliminary report. 19734207407
the use of hibitane for hospital disinfection. 19734213490
intensity of chemical mutagenesis in human cells as a function of age and sex. 19734216079
[the effect of ultraviolet rays on the microflora of meat]. 19734207537
[urinary tract infections in patients hospitalized in a department of internal medicine. bacteriological and clinical studies and therapeutic results in 925 cases]. 19734207438
comparison of porphyrin and heme biosynthesis in various heterotrophic bacteria. 19734208581
studies on antiseptic soap. 19734213403
immunochemical studies on glutamic acid decarboxylase (ec 4.1.1.15) from mouse brain. 19734198391
pyogenic vertebral osteomyelitis in heroin addicts.the diagnosis of pyogenic vertebral osteomyelitis was made in seven narcotic addicts between 1967 and 1972. vertebrae involved were either cervical or lumbar. bacteriologic diagnosis was made in each case by percutaneous needle biopsy and aspiration. staphylococcus aureus was cultured in two patients. five patients had infections due to gram-negative bacteria, including klebsiella pneumoniae, pseudomonas aeruginosa and enterobacter. all patients were cured by treatment with antibiotics and immob ...19734199351
aminoglycoside antibiotics. iv. bu-1709 e1 and e2, new aminoglycoside antibiotics related to the butirosins. 19734205652
basic studies on 3', 4'-dideoxykanamycin b. 19734205657
aminoglycoside antibiotic-inactivating enzymes in actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria.various species of streptomyces possess aminoglycoside-modifying enzymes. streptomyces kanamyceticus contains an enzyme that acetylates the 6'-amino group of kanamycin a and b, gentamicin c(1a), and neomycin. streptomyces spectabilis produces an enzyme that acetylates the 2'-amino group of the hexose ring of gentamicin c(1a). these enzymes catalyze reactions identical to those catalyzed by enzymes found in gram-negative bacteria containing r(antibiotic resistance)-factors. the discovery of these ...19734209515
letter: synthesis of (s)-4-amino-2-hydroxybutyryl derivatives of 3',4'-dideoxykanamycin b and their antibacterial activities. 19734209533
[role of the mesenchymal cells in the development of arteriosclerosis]. 19734196366
pharmacology of cyanate. i. general effects on experimental animals. 19734197279
[biochemical qualities of 14 strains of the genus klebsiella isolated from bovine mastitis]. 19734197682
testicular leucine aminopeptidase in different vertebrates. 19734197867
effects of bilirubin loading of pregnant rats on hepatic udp-glucuronyltransferase activity in the offspring. 19734204960
effect of colon flora and short-chain fatty acids on growth in vitro of pseudomonas aeruginsoa and enterobacteriaceae.heat-stable antibacterial activity in the following suspensions was demonstrated against pseudomonas aeruginosa at ph 6.5, 6.0, and 5.5: (i) pooled colon contents of normal mice; (ii) an anaerobic, 48-h culture of normal mouse feces; and (iii) anaerobic, 48-h cultures of different bacteria from human colon flora (escherichia coli, bacteroides fragilis, klebsiella pneumoniae, and proteus mirabilis). the lower the ph of the medium, the greater was the antibacterial activity of these suspensions. t ...19734198102
some properties of the uridine diphosphate glucuronyltransferase activity synthesizing thio-beta-d-glucuronides.1. some properties of the udp-glucuronyltransferase synthesizing thio-beta-d-glucuronides were investigated and compared with those of the enzyme synthesizing the o-glucuronides of analogous phenols. 2. enzyme activity was generally similar for both classes of substrate in tissue distribution, intracellular location, optimum ph, perinatal development and induction by organ culture or by phenobarbital. 3. certain differences were noted between the two types of activity in behaviour on storage and ...19734198582
a clinical and microbiological study of venous catheterization.in a prospective study of 210 intravenous catheters and needles 31 (15%) swabs yielded 34 microbial isolates. twenty-eight were "non-pathogenic" skin commensals and six were "pathogenic" organisms. commensals were isolated predominantly from catheters left in situ for only a short time (up to two days) and pathogenic organisms most frequently from specimens left in situ for a longer time. correlation was not confirmed between colonization and infection, antibiotic therapy or phlebitis. all sampl ...19734198593
clinical effectiveness of lividomycin on urinary tract infections: evaluation with double-blind method. 19734203572
the microbiology of gentamicin resistance. 19734205065
effect of dimethyl sulfoxide on natural resistance to bacterial infections in mice. 19734210025
production of lesions in various tissues by amino acids. 19734200263
the vaccination of man and other animals against rabies. 19734207636
pseudomonas bacteremia. evaluation of factors influencing response to therapy. 19734205064
[experimental tumors of the sciatic nerve in monkeys]. 19734206856
epidemiological problems in paediatric intensive therapy and resuscitation unit. 19734213084
receptive fields in single cells of monkey visual cortex during visual tracking. 19734213353
neurologic disorders following live measles-virus vaccination. 19734196154
selenium heterocycles. 8. synthesis and antibacterial activity of selenosemicarbazide and 1,3,4-selenadiazolylcarbamic acid esters. 19734196206
growth of bacteria and fungi in total parenteral nutrition solutions. 19734199595
activity of aminoglycoside antibiotics aganst pseudomonas aeruginosa: specificity and site of calcium and magnesium antagonism. 19734196445
laboratory experiments with uropathogenic bacteria and chlorhexidine. 19734196567
intrauterine pneumonia. an experimental study. 19734201065
terminal riboadenylate transferase: a poly a polymerase in purified vaccinia virus.purified vaccinia virus treated with triton x-100 catalyzes the incorporation of atp into an acid-insoluble product. the enzymatic activity responsible for the atp polymerization is demonstrated to be different from vaccinia rna polymerase in its preferential use of atp as substrate and on the basis of heat stability, ph optima, and metal ion requirement. the atp polymerization reaction is stimulated 10-fold by the addition of ra(pa)(5.) in accordance with our earlier terminology, we call this m ...19734201186
oxidation of furans. 2. synthesis and biological properties of 6-hydroxy-2h-pyran-3(6h)-ones and derivatives. 19734201420
preparation hoe 105 (citenazone) in chemoprophylaxis of variola in monkeys: a preliminary communication. 19734201915
accumulation of histidine, 3-methylhistidine, and homocarnosine in the brains of protein-calorie deficient monkeys. 19734201946
the effect of prenatal malnutrition on dimensions of cerebral cortex. 19734196753
electron microscopic study of endothelium of stored and cryopreserved monkey corneas. 19734202638
drug susceptibility-resistance pattern of gram-negative uropathogens to seven cephalosporins. 19734202701
acute cavitary histoplasmosis in rhesus monkeys: influence of immunological status.male rhesus monkeys were randomized into groups according to body weight, immunized with different histoplasma capsulatum antigens, and two weeks later were infected intratracheally with 10(8)h. capsulatum yeast cells. complement fixation antibody titers, skin tests, and chest x rays were performed at weekly intervals from immunization until autopsy, at which time the spleens were cultured and the lungs and other organs were dissected. pulmonary cavities were found in 33% of the animals, and ext ...19734199155
studies on in vitro dna synthesis. purification of the dna g gene product from escherichia coli.varphix174 dna-dependent dnmp incorporation is temperature-sensitive (ts) in extracts of uninfected e. coli dna a, b, c, d, e, and g ts strains. dna synthesis can be restored in heat-inactivated extracts of various dna ts mutants by addition of extracts of wild-type or other dna ts mutants. a protein that restores activity to heat-inactivated extracts of dna g ts cells has been extensively purified. this protein has also been purified from dna g ts cells and is thermolabile when compared to the ...19734197093
involvement of a carboxyl group in the active site of bacillus cereus 569-h penicillinse ( -lactamase i). 19734197157
chromatographic separation of two ionic strength dependent conformations of valine transfer ribonucleic acid of bacillus subtilis. 19734198186
[statistical observation on chronological changes of sensitivity of various bacteria to antibiotics. 1. gram negative bacilli; escherichia coli, bacillus pneumoniae, proteus vulgaris, alcaligenes faecalis, cloaca, providencia, citrobactor, pseudomonas aeruginosa (1966-71)]. 19734198261
antimicrobials. new nitrofuran derivatives. 19734200221
[submicroscopic structure of the bacterial cell wall (review of the literature)]. 19734206610
[on the antibacterial effect of subinhibitory concentrations of tetracycline (author's transl)]. 19734206734
penicillinases of klebsiella pneumoniae and their phylogenetic relationship to penicillinases mediated by r factors.on the assumption that the penicillinase determinants on a group of r factors conferring ampicillin resistance have a phylogenetically close relationship to the penicillinase gene of the klebsiella group, the penicillinases from four strains of k. pneumoniae, gn69, gn1103r(-), gn422, and gn118, were purified 230- to 1,000-fold and compared with the known two r-factor-mediated penicillinases. by gel filtration on sephadex g-75, the molecular weights were estimated to be 17,400, 18,100, 20,000 and ...19734199503
consequences of smallpox vaccination in leprosy patients.this study illustrates the consequences of smallpox revaccination in 45 lepromatous, 28 tuberculoid, and 47 normal individuals. results obtained with intradermal inoculations indicated that the patients with leprosy were associated with a relative anergy against the vaccinia virus, the anergy being minimal in the tuberculoid leprosy but marked in the cases with lepromatous leprosy. major vaccinial reactions were observed more often in patients with lepromatous leprosy than in the controls or pat ...19734199714
[differentiation of hypothalamic sex in subhuman primates and in man]. 19734199935
[sensitivity of t. vaginalis donné and other vaginal microorganisms to macmiror in vitro]. 19734200156
early events in cell-animal virus interactions. 19734200163
thiourea derivatives of 2-aminooxazoles showing antibacterial and antifungal activity. 19734203141
[photosynthetic membranes of biliprotein-containing algae observed after freeze etching]. 19734200556
activity of magnocellular neuroendocrine cells in the hypothalamus of unanaesthetized monkeys. ii. osmosensitivity of functional cell types in the supraoptic nucleus and the internuclear zone.1. we studied magnocellular neuroendocrine cells and non-neuroendocrine cells in the supraoptic nucleus (n.s.o.) and internuclear zone (i.n.z.) in the hypothalamus of unanaesthetized, chronically prepared monkeys. after antidromic identification, functional cell typing and sensory testing we injected solutions of varying tonicity into an implanted carotid cannula to determine osmosensitivity.2. on the basis of the anatomical location of the cells, the pattern of discharge in response to osmotic ...19734202433
one stage cardiac denervation without transplantation. 19734202435
[purification of bacteriophages on sepharose by gel chromatography]. 19734208006
[an application of universal determination of body fluid protein-concentration. ii. 131-i-bsp binding human serum proteins (author's transl)]. 19734202437
multiplication of nosocomial pathogens in intravenous feeding solutions.a major problem in total parenteral nutrition is sepsis, particularly that caused by candida. studies of four solutions, a casein hydrolysate, a fibrin hydrolysate, and two crystalline amino acid solutions, show that the protein hydrolysate solutions appear to be highly selective for candida over bacteria, whereas the crystalline amino acid solutions are not. these findings suggest that the crystalline amino acid preparations may offer a partial solution to the infection problem by minimizing th ...19734203333
effect of propylene oxide treatment on the microflora of pecans.studies were conducted to determine the effectiveness of propylene oxide (po) treatment in controlling the microflora of pecans. as used commercially, po has little effect on internal bacteria and fungi in pecan halves. tests of surface washings of commercially treated pecans showed a reduction of 96% in coliform bacteria following po treatment. under controlled laboratory conditions, po gave 80 to 92% reduction of surface microflora and at least 64% reduction of internal flora, but neither bact ...19734202707
a test for nucleotide sequence homology. 19734203659
the role of multivalent cations in the uptake and oxidation of glucose by pseudomonas fluorescens.the effects of mg(2+), mn(2+), ca(2+) and fe(3+) on the uptake and oxidation of glucose in induced and non-induced pseudomonas fluorescens cells were studied. mg(2+) is the most effective single metal ion in the uptake of glucose by the cell, and it functions in membrane stabilization and enzymic activity. ca(2+) will substitute for mg(2+), but mn(2+) and fe(3+) will not.19734204323
intestinal carriage of klebsiella and pseudomonas in burned children and their comparative role in nosocomial infection. 19734198320
[effect of pyocyanic infection on wound healing in experimental animals]. 19734136138
[improvement of surgical curability in lung cancer]. 19734147230
[studies on the determination of nalidixic acid-resistance of r-plasmids in e. coli]. 19734147408
concentration of echoviruses by polyethylene glycol. 19734150027
[pathological significance of the surface of crystalline silicogenic dust in experimental silicosis]. 19734122316
immunofluorescent demonstration of an intra-articular antigen-antibody complex in experimental arthritis of the guinea-pig. 19734120914
[topical use of phosphonomycin]. 19734120915
the ultrastructure of the capsules of diplococcus pneumoniae and klebsiella pneumoniae stained with ruthenium red. 19734121098
distribution of the human average movement potential. 19734121319
herpesvirus hominis: from latency to carcinogenesis? 19734137697
group b arbovirus structural and nonstructural antigens. ii. purification of saint louis encephalitis virus intracellular antigens.three serologically distinct antigens were identified in homogenates of saint louis encephalitis (sle) virus-infected cells after brij-58 solubilization and diethylaminoethyl (deae)-cellulose chromatography. these antigens were designated as antigen i, ii, and iii. immunodiffusion analyses showed that all antigen peaks which eluted from the deae-cellulose column contained the intracellular major envelope protein, antigen i. this protein was the only viral antigen which eluted at 0.125 m kcl in d ...19734131772
inhibition of migration of guinea pig macrophages and mouse spleen cells by unconcentrated human mif in serum-free medium. 19734134367
detection of the "pregnancy zone" protein by means of an immunodiffusion method. 19734120261
detection of the "pregnancy zone" protein by means of an immunodiffusion method. 19734120261
antigenic determinants in the n-terminal part of bovine encephalitogenic protein studied with the macrophage migration inhibition assay in guinea pigs. evidence for an immunological reactivity of peptide 1-43 when tested on cells from animals injected with freunds's complete adjuvant. 19734125507
flower vases in hospitals as reservoirs of pathogens. 19734127638
[protein electrophoresis after homologous spleen transplantation in the dog]. 19734128467
changes in the timm sulfide silver staining pattern of the rat hippocampus and fascia dentata following early postnatal deafferentation. 19734131249
introductory immunologic studies on human gastrointestinal tract tumors. 19734131722
introductory immunologic studies on human gastrointestinal tract tumors. 19734131722
drug-protein binding: a method for studying the interactions of drugs with bishydroxycoumarin (dicoumarol) in dogs. 19734129139
relation between pressure and sodium excretion in perfused kidneys from rabbits with experimental hypertension. 19734128057
renewal of proteins and glycoproteins of synaptic constituents by means of axonal transport. 19734128237
cultures of tissues from patients with amyotrophic lateral sclerosis. 19734126530
the ecology of whataroa virus, an alphavirus, in south westland, new zealand.the findings of a survey on the ecology of an alphavirus over the years 1964-9 are reviewed. evidence is presented to show that wild birds constitute a vertebrate reservoir of the virus and that mosquitoes, primarily culiseta tonnoiri and culex pervigilans, which are both endemic new zealand species, are responsible for summer transmission.serological evidence of infection was obtained in all years and evidence is presented to indicate that the virus is enzootic rather than being reintroduced ea ...19734149068
[proceedings: intraepithelial filaments in the human kidney]. 19734142234
proceedings: the absorption, distribution, and excretion of 2-amino-4-phenylsulphonyl benzene sulphonamide (nsd 3004) in rats. 19734150543
further studies regarding the structure activity relationships of beta-adrenoceptor antagonists.1. the ortho (m66,527) and para (m66,368) analogues of 1-t-butylamino-3-(methoxyphenoxy)-2-propanol and para substituted tertiary butylphenoxy-1-n-isopropylamine-3 propanol-2 oxalate acid (l8429) were tested in dogs for their beta-adrenoceptor blocking activity.2. m66,527, which contains a methoxy group in the ortho position of the benzene ring, was found to be comparable to propranolol in blocking cardiac and peripheral vascular responses to isoprenaline. like propranolol, m66,527 was more pote ...19734150921
transmission of kyasanur forest disease virus by the soft tick, ornithodoros crossi. 19734148214
the effects on cardiac muscle and nerve of a fluorinated decahydroquinoline derivative, l7810, rapidly absorbed after oral administration.1. l7810 (4-carbamoyloxy-1-(4-(4-fluorophenyl)-4-oxobutyl) decahydroquinoline, has a local anaesthetic action on frog nerve 1.75 times that of procaine.2. l7810 protected anaesthetized guinea-pigs against ouabain-induced ventricular fibrillation and increased the lethal dose of ouabain.3. l7810 reduced the rate of rise of intracellularly recorded action potentials in rabbit isolated atria; the resting potential was not affected, but the duration of the action potential was prolonged.4. unlike mo ...19734147426
cefazolin in the treatment of bacterial pneumonia. 19734147579
synthesis of cephapirin and related cephalosporins from 7-(alpha-bromoacetamido)cephalosporanic acid. 19734148798
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