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1-n-alkyl analogs of butirosin.butirosin (ia), 5''-amino-5''-deoxy-(ic), 3',4'-dideoxy-(ie), and 5''-amino-3',4',5''-trideoxy-butirosin a (if) were converted into the corresponding 1'''-deoxo derivatives, ib, id, ig, and ih by borane reduction. in addition, xylostasin (iiia) was converted into its 1-n-ethyl derivative (iiib) by reductive ethylation. their antibacterial activities were discussed.200094324
phosphonoformate inhibits reverse transcriptase.the new antiviral substance phosphonoformate (pfa) has been tested in a cell-free system for its effect on reverse transcriptases from an avian retrovirus (avian myeloblastosis virus, amv) and from mammalian retroviruses (rauscher leukaemia virus, rmulv; bovine leukaemia virus; baboon endogenous virus; simian sarcoma virus; visna virus). the observed inhibitory effect of pfa has been compared with that of a structurally related substance, phosphonoacetate (paa). phosphonoformate, at a concentrat ...197994344
priming increases the amount of interferon mrna in poly(ri).poly(rc)-treated l cells.priming by mouse interferon pre-treatment resulted in an accumulation of interferon mrna in poly(ri).poly(rc)-treated l cells, starting early in the period of interferon synthesis. on electrophoresis, the priming activity of an interferon preparation co-migrated with the antiviral activity, which suggests identity of the functional principle(s) for these activities.197994345
characterization of the coronary vasodilator and hemodynamic actions of monensin, a carboxylic ionophore.the effects of monensin on coronary blood flow (cbf) and other hemodynamic parameters were studied in anesthetized dogs. a dose-response relationship was established, and it was found that the lowest doses of monensin (5-25 micrograms/kg) produced a dose-dependent increase (3-5x) in cbf with a concomitant decrease in total peripheral resistance (tpr). pretreatment with diphenhydramine, atropine, indomethacin, or propranolol resulted in no reduction in peak increase in cbf or in the duration of r ...197994374
methylprednisolone sodium succinate treatment in global ischemia of the cat isolated heart.effects of methylprednisolone were studied on isolated, blood-perfused cat hearts subjected to 1 hr of normothermic ischemic arrest. untreated hearts sustained decreases in peak ventricular pressure pulse, dp/dt, and ventricular compliance. ischemic hearts also became edematous, gained sodium, and lost potassium and creatine kinase enzyme activity. steroid treatment did not significantly alter any of these ischemia-induced changes. methylprednisolone treatment did increase resting coronary flow ...197994382
electrophysiological actions of lorcainide in patients with cardiac disease.lorcainide is a new antiarrhythmic agent which effectively suppresses ventricular premature contractions. its electrophysiological actions were studied in 15 cardiac patients with and without cardiac conduction abnormalities. in a dose of 2 mg/kg body weight, lorcainide decreased the sinus cycle length (scl) and increased the corrected sinus node recovery time. the intra-atrial, atrioventricular (av), and intraventricular conduction times were prolonged. a third-degree av block developed in 2 pa ...200094401
disopyramide plasma and myocardial tissue concentrations as they relate to antiarrhythmic activity.antiarrhythmic concentrations of disopyramide in canine plasma and myocardium were determined by gas chromatography. ventricular tachycardia was incuded in anesthetized dogs by the intravenous administration of ouabain. disopyramide phosphate was then administered by a two-stage continuous infusion method. a rapid infusion of disopyramide (9.08 mg/kg/hr) was administered for 30 min, followed by a slow infusion (2.18 mg/kg/hr) to maintain steady-state plasma levels of 1.98-2.21, mean +/- sem = 2. ...197994410
[endogenous peptides and analgesia]. 200094442
effect of subminimal inhibitory concentrations of mecillinam on the synthesis of dna, rna, and protein of salmonella typhimurium: a proposed mechanism of action.salmonellae alter their rod-like morphology to become large ovals within 3-5 hr after being exposed to concentrations of mecillinam below the minimal inhibitory concentration. before this overt morphologic change occurs, synthesis of dna increases, with a concomitant decrease in total protein synthesis. incorporation of [3h]leucine into cell wall protein is markedly inhibited by mecillinam, whereas incorporation of leucine into soluble intracellular proteins is enchanced by the drug. electrophor ...197994451
hereditary alpha 2-macroglobulin deficiency.on screening of a normal material 1 man was found (age 37) who on repeated determinations had a low alpha 2m, namely 25 % with electroimmuno assay according to laurell. investigation of the family revealed that the mother (age 69) and one daughter (age 5) had low values too. all other coagulation and fibrinolytic components were normal. they had no signs of increased fibrinolysis and normal levels of alpha 2-antiplasmin, alpha 1-antitrypsin and antithrombin iii. liver function tests were normal. ...197994459
[amniocentesis for antenatal diagnosis. a report on an initial series of 180 cases (author's transl)].the results are presented of amniocentesis for diagnostic genetic purposes in 180 patients. a diagnosis was obtainable in 170 cases (94%). genetic abnormalities were detected in 11 cases; one patient miscarried 3 days after amniocentesis. antenatal diagnosis of certain genetic disorders can be considered a routine method nowadays and should be offered to any woman at risk. it therefore seems necessary to supply the practitioners with the relevant information on this topic.200094482
a detergent-citric acid technique for isolating nuclear and cytoplasmic fractions containing undegraded rna from cells of xenopus laevis. 197994513
rapid isolation of rna using proteinase k and sodium perchlorate. 197994516
factors involved in the age-dependent resistance of mice infected with low-virulence mouse hepatitis virus.four-week-old weanling mice survived, whereas 1-week-old suckling mice died, after intraperitoneal inoculation of mouse hepatitis virus, mhv-s strain. the factors involved in this difference in susceptibility were studied. after virus inoculation, differences in virus growth in the liver and spleen were observed, which correlated with the susceptibility of animals to the virus. interferon, detected at an early stage of infection, was considerably lower in suckling mice than in weanling mice. tit ...197994538
pathophysiology and pharmacotherapy of spasmodic torticollis: a review.the few existing neuropathological, neurochemical, and neuropharmacological studies have shed little light on the pathophysiology of spasmodic torticollis (st). the relevance of experimental st in animals and drug-induced st in man to idiopathic st is unclear. most pharmacotherapeutic endeavors have focused on drugs affecting basal ganglia function. unfortunately, problems of sample size, clinical heterogeneity of patient population, research design, objective evaluation of response, documentati ...197994551
correlation of a specific chromosomal marker, 21q-, and retroviral indicators in patients with thrombocythemia.a chromosomal anomaly, 21q-, has been found in association with retroviral indicators in patients with myeloproliferative disorders (mpd) including polycythemia vera (pv), essential thrombocythemia (et), chronic myelocytic leukemia (cml) and acute non-lymphocytic leukemia (anll). the viral indicators are found in platelet homogenates of thrombocythemic patients. evidence is presented from 2 laboratories (philadelphia, usa and bologna, italy) for the 21q- deletion in mpd patients. thirty patients ...197994552
isolation and characterization of bleomycin-resistant clones of cho cells. 200094572
cell-free protein synthesis and interferon action: protein kinase(s) and an oligonucleotide effector, pppa2'p5'a2'p5'a. 200094574
quantitative estimation of hemoglobin and its fractions in permanent mountain dwellers in the tyan'-shan' and pamir. 200094587
toxicity to the nervous system of diphenylhydantoin: a review. 200094596
the errors in assembly of mulv in interferon treated cells.interferon treatment of jlsv-6 cells chronically infected with rauscher mulv leads to the formation of noninfectious particles (interferon virions) containing the structural proteins of env and gag genes as well as additional viral polypeptides. in the control virions the major glycoprotein detected is gp71, interferon virions contain in addition to gp71 and 85k dalton (gp85) glucosamine-containing, fucose-deficient glycoprotein which is recognized by antiserum to mulv but not by the gp71 antise ...200094615
acute and chronic beta-receptor blockage with propranolol and the cardiovascular responses to intravenous sodium nitroprusside in the conscious rabbit.sodium nitroprusside infused intravenously into conscious rabbits lowered blood pressure and raised heart rate and plasma noradrenaline. acute beta blockade with propranolol, 2 mg/kg/hr i.v. for 2 hr, increased resting plasma noradrenaline and did not change the hypotensive effects of nitroprusside or the rise in plasma noradrenaline but attenuated the increase in heart rate. chronic treatment with propranolol, 2 mg/kg twice daily for 3 weeks, did not modify the cardiovascular or reflex effects ...197994618
do overlapping genes violate molecular biology and the theory of evolution? 200094642
[duodenal endoscopic macrophotography using a zoom lens following in vivo staining]. 200094648
[is treatment with interferon already possible?]. 200094668
alcian blue and tannic acid in the studies on pulmonary alveolar lining layer. 197994744
increase of phosphoribosylpyrophosphate levels in cultured l1210 leukemia cells exposed to methotrexate. 200094762
immunologic detection of lesions in dna [proceedings]. 200094783
dielectric perturbation of hydrogen-bonded systems by high electric fields [proceedings]. 200094784
quantitative study of the energy conversion in halobacterium halobium [proceedings]. 197994791
light scattering on solutions of biopolymers : a critical evaluation of the technique [proceedings]. 200094799
[role of calcium in realization of nervous control during rna synthesis in skeletal muscles].the effects of ca2+ on the rna polymerase activity of the nuclei isolated from normal and denervated gastrocnemius muscles of the rabbit were studied. it was shown that 18 hrs after denervation the rna synthesis in vitro, ca2+ content and the ca, mg-atpase activity of the nuclei are decreased. after addition of exogenous ca2+ the incorporation of labelled utp into the nuclei is stimulated in the denervated muscle and is inhibited in the control. electrostimulation of the denervated muscle at the ...197994840
[prevention of reinfarction with acetylsalicylic acid].a report is presented on the prospective trial for prophylaxis of myocardial reinfarction by means of acetylsalicyclic acid. for the first time it was organized on the basis of population. 1,340 patients were treated with acetylsalicylic acid or placebo respectively for 22 months on an average. there were 24 cases of reinfarction in the group of treatment and 51 in the placebo group. the difference is significant.200194871
[prevention of cardiovascular complications in manifest arteriosclerosis by the use of micristine].a long-term clinical trial in micristin-treated patients suffering from organic arterial circulatory disturbances is reported. problems of therapy monitoring by determination of the asa level in plasma and of control of platelet aggregation are discussed. acute cardiovascular complications (myocardial infarction, stroke, acute vascular occlusion, amputation and angiographically demonstrated progression) were observed. the observation time did not suffice to establish statistically significant di ...200194872
pyrazolidine derivatives: a comparative study of their effects on platelet aggregation.quantitative studies were carried out of the in vitro and ex vivo effects of phenylbutazone and 3-oxoalkyl substituted diphenyldioxopyrazolidines (kebuzone, tribuzone, benzopyrazone) on platelet aggregation. the specified pyrazolidine derivatives exhibited in vitro inhibitory effects on secondary platelet aggregation (induced by adrenaline and collagen), commensurable with the effects of sulfinpyrazone. the ex vivo efficacy was markedly influenced by the height of the drug level in blood and by ...197994876
[preparation of human platelets without the use of anticoagulants and study of the effect of catt on aggregation].a method for the preparation of human blood platelets is presented which substitutes the use of anticoagulants by a gelfiltration for the removal of plasma calcium from native blood. in a second step the platelets are separated from the gel filtered blood by a centrifugation on a ficoll density gradient. the anticoagulant-free platelets reveal an intact morphological feature and a normal aggregation behaviour in response to different aggregation inducers. it was found that in adp-induced aggrega ...197994881
[the mechanism of thrombolysis with streptokinase]. 200194883
induction of monoclonal antibody synthesis in malignant human b cells by polyclonal b cell activators. relationship between b cell subsets and prognosis. 197994897
ability of enriched immune t cells to confer resistance in hamsters to infection with treponema pertenue.this investigation presents the first direct evidence that t cells are involved in resistance to challenge with treponema pertenue. enriched t cells from immune hamsters were obtained by sequential filtration through glass and nylon-wool columns. this procedure removed the majority of functional antibody-producing and immunoglobulin-bearing cells. the fractionated cell suspensions were less responsive to stimulation by phytohemagglutinin, lipopolysaccharide, and dextran sulfate, but they were en ...197994906
role of interferon in mice in protection against influenza a virus by bacterial ribosomes together with membranal glycoproteins of klebsiella pneumoniae as adjuvant.nonspecific protection against infectious aerosols of influenza a virus was obtained in swiss mice after vaccination by aerosols of bacterial ribosomes together with membranal glycoproteins extracted from klebsiella pneumoniae as the adjuvant. it was shown that repeated stimulant aerosols were necessary to obtain this protection. routine estimation of serum interferon levels after administration of the association of ribosomes plus membranal glycoproteins to the animals by aerosol or intravenous ...197994908
determination of kepone dechlorination products in finfish, oysters, and crustaceans. 200194920
electron microscope histochemistry of acetylcholinesterase distribution in the optic tectum of teleosts.an ultrastructural analysis was made on acetylcholinesterase (ache) localization in the optic tectum of two teleosts, the goldfish and the catfish. electron microscope histochemistry reveals several details on synthesis, distribution and possible sites of utilization of the enzyme in the different tectal layers. the results show that ache is synthesized by all the neuronal types present in the optic tectum. the final localization of the enzyme is the result of its synthesis in cell bodies, its s ...200194927
cholesterol in high-density lipoproteins: a comparison between dextran sulfate-magnesium chloride precipitation and preparative ultracentrifugation.the cholesterol in high density lipoproteins (hdl) has been determined in 140 serum samples after dextran sulfate-magnesium chloride precipitation of the apolipoprotein b-containing lipoproteins. the values correlated well with simultaneously measured values from preparative ultracentrifugation (slope 0.98, r = 0.93). furthermore, there was a significant correlation in 60 specimen between the dextran sulfate-mgcl2 and heparin-mncl2-precipitation method.200194930
staining with chromoxane cyanine r.since pearse in 1957 introduced chromoxane cyanine r as a dual nuclear and cytoplasmic stain there have appeared numerous procedures for use of this dye. these have differed widely, sharing in common mainly the implication that each is best. a defendable procedure has been developed on an experimental basis and is reported here. four stock solutions are needed: (1) a 0.2% solution of chromoxane cyanine r in 0.5% aqueous h2so4 (v/v); boil this solution for 5 min, (2) 10% fecl3 in 3% hcl, (3) 1% a ...197994954
[interferon in the anti-influenza protection provided by a mixtures of bacterial ribosomes and a membrane fraction of k. pneumoniae applied as an aerosol]. 197994959
[quantitative disc electrophoretic determination of amylase activity in the urine with regard to age]. 200194964
therapeutic effect of intravenously administered yeast glucan, in mice locally infected by mycobacterium leprae. 197994971
affinity sensors for individual metabolites.specific metabolite sensors may be constructed for species when a specific binding agent and optically detectable competing assay ligands are available.200194999
[intracellular localization of alpha-fetoprotein and serum albumin in the central nervous system of the rat during fetal and postnatal development].the morphological localisation of alphafetoprotein (afp), serumalbumin (sa), transferrin and immunoglobulins (igg) has been studied in the developing central nervous system of the rat by immunocytochemical methods. evidence is presented of a highly selective staining for afp and sa, both proteins exhibiting the same topographical distribution. practically all the areas of the brain and the spinal cord are stained at a given moment of the developmental process. the labeling is cytoplasmic and in ...197995002
[repeated palliative measures for intrathoracic neurofibrosarcoma and hypoglycemia]. 200195005
[respective position of antidepressants in therapeutics (author's transl)].the author points out the heterogeneity of depressions and antidepressants. he stresses the need of finding predictive indicators of antidepressant activity. genetic, "demographic", biological, biochemical and pharmacokinetic factors can help to guide antidepressant's prescription. urinary mhpg dosage seems to be one of the most interesting in this field.200195010
reactivity of monoclonal antibodies specific for h-2 antigenic determinants with cells of wild mice. 200195013
monoclonal antibodies for analysis of the hla system. 200195015
effect of temperature on the dielectric pattern of dna-actinomycin d complex. 200195017
the need for quality hospice care. 200195042
[so-called refractory hypoxemia: treatment with acexamic acid].acexamic acid is currently used to avoid pulmonary fibrosis in patients treated with bleomycim. it seems to be equally effective to prevent pulmonary fibrosis in adult respiratory distress syndrome. the complications of this therapy are hypercalcemia and hypernatremia.200195046
[influence of parotin on the repressing action of cyanylethyl group to histamine stress (author's transl)]. 197895057
fundus changes in sarcoidosis. review of 33 patients with histological confirmation.a series of 33 patients with histological evidence of sarcoidosis and a retinopathy is reviewed. the fundus can be involved in the absence of anterior uveitis and involvement may be grossly asymmetrical. the most common lesion was a retinal periphlebitis which can progress to occlusion and neovascularization at the same site or at the optic disc. focal chorio-retinal changes frequently occur, usually without serious visual loss. central retinal vein or large branch vein occlusions did not occur ...200195061
the keraton. a biological unit of the epidermis.the term keraton is proposed to denote that specific subpopulation of epidermal cells that matures to form epidermis and horny layer exclusive of other functional units within the epidermis such as melanocytes, acrosyringium, acrotrichium, langerhans' cells, and nerves.200195081
the role of bulk and surface properties of selected amino acid copolymers on blood coagulation. 200195084
demonstration of a murine cell surface component with affinity for exogenous beta 2-microglobulin.murine and human beta 2-microglobulin (beta 2m) bind to various types of mouse cells. the binding is saturable and displays a single association constant of about 1 x 10(9) liter/mol. the binding of beta 2m to splenocytes was not affected by a variety of metabolic inhibitors but was temperature-dependent. it is suggested that the beta 2m "receptor" exhibits a temperature-dependent conformational change since the "receptor", whether integrated into the membrane or solubilized by the detergent tri ...197995108
synthesis of nucleic acids by bone marrow cells from patients with iron deficiency anaemia. 200195112
electrokinetic study of the reactions of peritoneal macrophages and eosinophils with igg immune complexes.electrophoretic light scattering (laser doppler electrophoresis) has been employed to study the effects of guinea pig igg immune complexes on the electrophoretic mobility distributions of guinea pig resident peritoneal cells. the resident population of cells is composed of macrophages (approximately 75%) and eosinophils (approximately 25%). these cells were separated according to the well-established method of boyum. populations of resident macrophages, eosinophils, and the unfractionated sample ...197995166
subclassification of murine t cells by computerized microphotometric analysis.splenocytes separated by physical means and classified as t cells bay immunologic tests and computerized microphotometric analysis are differentiated into subgroups by analysis of the distribution patterns of feulgen-positive nuclear dna. in like fashion t cells obtained as purified preparations after separation on a nylon column, and accepted as t cells by micromorphometric analysis were subjected to further computerized morphometric analysis of nuclear dna to form subgroups of cells. in each c ...200195181
ribonucleotides in dna newly synthesised in 3t6 cells in vivo.within the field of dna replication, considerable interest has focused in recent years on the mechanism of initiation of synthesis of dna molecules. in vitro replication systems from escherichia coli have been instrumental in uncovering a priming function fo9r ribonucleotides on the earliest intermediates of dna polymerisation in vitro and in identifying the proteins involved. in vitro replication systems from mammalian cells that permit the use of the phosphate-transfer method for detection of ...197995207
[study of 4 cases of massive acute interstitial pathology of the lungs (adult respiratory distress syndrome or ards)]. 200195212
pacing-induced alternate wenckebach periods: incidence and clinical significance.alternate wenckebach periods have been defined as episodes of 2:1 atrioventricular (av) block in which conducted p waves exhibit progressive pr prolongation until two or three successively blocked p waves. ocurrence of this phenomenon during atrial pacing has been established. thirty-six patients were studied and right atrial pacing was achieved at increasing rates up to 350 beats/min in order to induce alternate wenckebach periods. his bundle recordings were obtained in every patient. the patie ...200195224
aggression in humans correlates with cerebrospinal fluid amine metabolites.cerebrospinal fluid of the major central metabolites of serotonin (5ht), norepinephrine (ne), and dopamine (da)--5-hydroxyindoleacetic acid (5hiaa), 3-methoxy-4-hydroxy=phenylglycol (mhpg), and homovanillic acid (hva), respectively--were studied in a group of 26 age-similar military men with no history of major psychiatric illness, but with various personality disorders and difficulties adjusting to military life. independently scored history of aggressive behavior showed a significant negative ...200195232
determination of small differences in buoyant density of macromolecules by analytical density gradient equilibrium centrifugation.a sensitive method is proposed for the determination of small differences between the buoyant densities of different species of monodisperse macromolecules by analytical density gradient equilibrium centrifugation. the procedure involves the measurement at sedimentation equilibrium of the bandwidths of the concentration distribution of the separate macromolecules and of a mixture of the different species. the difference in buoyant densities can then be estimated from the difference between the b ...200195253
mode of operation induced by rapid external chest wall stimulation in patients with normally functioning qrs-inhibited (vvi) pacemakers.the effects of rapid external chest wall stimulation were evaluated in 10 patients with normally-operating unipolar, lithium-powered, qrs-inhibited pacemakers functioning in their control vvi (qrs-inhibited) mode. stimuli delivered at slow rates resulted in the expected pacemaker inhibition. on the other hand, during rapid (greater than 900/min) external chest wall stimulation, 8 pacemakers reverted to a voo mode, 1 to a vvi mode and 1 to either a vvi or voo mode. no pacemaker was totally inhibi ...200195261
dual-demand pacing for refractory atrioventricular re-entry tachycardia.an automatic dual-demand pacemaker has been used in six patients to treat refractory attacks of paroxysmal re-entry atrioventricular tachycardia that occurred in the wolff-parkinson-white syndrome. the pacemaker was designed to pace at a fixed rate of 70 beats per minute when sensed heart rates were either below this rate or above 150 beats per minute; in the latter case, it would compete with the paroxysmal tachycardia and interrupt it after a short period of random scaning. the best location f ...200195273
ventricular pacing from the middle cardiac vein mimicking supraventricular morphology.a case is described in which ventricular pacing from the middle cardiac vein produced an electrocardiographic pattern which mimicked the morphology of the normally conducted beats. the possible etiologies of this unusual phenomenon and its implications concerning the functional anatomy of the normal conduction system in the human heart are discussed.197995282
radiation from implantable nuclear pacemakers. i. dosimetry. 200195284
unusual demand pacemaker arrhythmia due to partial recycling in the relative refractory period.this report presents the electrocardiograms of a patient with a normally functioning lithium qrs-inhibited pulse generator that exhibited partial recycling with inappropriately short escape intervals. the occurrence of partial recycling was time-dependent rather than voltage-dependent, and was observed only when qrs complexes fell within the relative refractory period of the pulse generator. this resulted in a complex arrhythmia simulating pulse generator malfunction. this observation re-emphasi ...200195285
reuse of the implanted cardiac pacemaker. 200195290
symptomatic sinus node disease: natural history after permanent ventricular pacing.fifty-nine patients between the ages of 13 and 88 with sinus node disease, who received a permanent ventricular pacemaker between 1965 and 1976 at one institution, were followed to determine the natural history of the disorder after permanent pacing. nineteen had ischemic heart disease, six had primary myocardial disease, and eight valvular heart disease. in 26, no etiology for the arrhythmia was apparent. the one- and five-year survival was 85.5% and 73.1%, respectively. patients with underlyin ...200195295
terminology and electrophysiologic concepts in cardiac arrhythmias. v. phase 3 block and phase 4 block. part 1. 197995299
runaway cordis omni-stanicor pacemaker. 200195306
immunodiffusion study on group-specific antigen of mc-29 chicken hepatoma.rabbit serum against crude mc-29 hepatoma extract does not contain anti-avian gs antibodies detectable by gel diffusion methods. rabbit serum containing antibodies against purified gs 1, gs 2, gs 3 and gs 4 antigens of avian myeloblastosis virus reveals gs 1 antigen in mc-29 hepatoma extract.197995333
[correlation between supraventricular extrasystoles and ventricular ectopic activity: description of 1 case]. 200195336
visualisation of the diffuse endocrine system. 200195342
hormonal control of gene expression: differential activation of rat bone marrow rna polymerases by erythropoietin and testosterone.hormones play a role in the regulation of gene expression by inducing changes in enzyme patterns in target cells mediated by the synthesis of specific rna molecules. erythropoiesis has been used as a system for studying the molecular mechanism of regulation of gene action by means of two hormones: erythropoietin and testosterone. experiments designed to correlate the biochemical action of both hormones on rat marrow cells are herein reported. both factors seems to act at different biochemical an ...197995387
embryonic gene regulation: role of an inducer rna in manipulation of embryonic gene functions. 200195389
pathogenesis of proliferative neovascular retinopathies and the role of vitrectomy. a hypothesis.proliferative neovascular retinopathies may be caused by the release of a hypothetical vasoproliferative factor, but mechanical factors seem to self-perpetuate the disease as well. contraction of proliferative tissue causes vitreous detachment and traction on the retina. congestion of vascular fronds by traction further stimulates vascularization. traction on vessels results in hemorrhages. surgical removal of all intravitreal scaffolds by vitrectomy seems to eliminate the development of this vi ...200195405
[replacement solutions and hemodilution].by definition, haemodilution involves the use of filling solutions, but in this technique the role of different solutions has yet to be clearly defined. amongst the criteria of choice used at the present time, two would seem to be essential: good tolerance, limiting the risks of complication and side effects to an absolute minimum; and a sufficiently long intravascular half-life ensuring good control of blood volume. on this basis, amongst the crystalloids ringer lactate offers definite advantag ...197995461
biochemical and energetic gradients in the mucosa of stomach and duodenum of patients with antral ulcer.separation and measurement of adenine-adenosine, adenosine monophosphate (amp), adenosine diphosphate (adp), adenosine triphosphate (atp), lipid phosphates, rna and dna, further, separation and measurement of mg2+-dependent, total (mg2+-dependent plus na+--k+-dependent, mg2+-na+-k-dependent) and na+-k+-dependent atpases were carried out in the mucosa and muscles of the corpus, antrum and duodenum of 68 patients with antral ulcer. it was found that (1) the substrate levels of adenosine nucleotide ...200195466
[immunological problems in oncology (author's transl)].the authors, after a view of the problems of immunology, regarding the most recent discoveries, deal with the conclusions about the immunological reactions in research and clinical oncology. many specific antibodies, formed as a result of the tumor, have been discovered in the field of research. it is impossible to say the same about human tumors and the probable hypothesis are numerous. the results until now obtained, even if they don't give a definite response, show that the immune defense of ...197995475
on the occurrence and prognosis of aphasia in patients with cerebral infarction.of 338 consecutive patients with cerebral infarction, aphasia in the acute phase was found in 96. of these, 18 had totally recovered from aphasic speech disturbances when leaving the hospital. the patients were examined 2-8, in average 6 years after the onset of the illness. 39% of them had died, 27% still suffered from aphasic speech disturbances, while 32% were recovered from aphasia. in addition, disturbances in writing, reading, and/or calculation were observed in more than the half of the s ...200195489
[combined intra-arterial proliferation inhibition and irradiation. a curative, cell kinetic therapy concept for carcinoma of the jaw and facial area]. 200195492
[local radiotherapy and adriblastin chemotherapy in metastatic breast carcinoma]. 200195495
[clinical evaluation of the use of prifinium bromide in urologic patients]. 200195506
[acute mercury poisoning in children (author's transl)]. 200195513
hormone receptors. 200195535
[morphological and histoenzymatic changes in the white rat testis after long-term administration of low doses of lindan and trichlorfon (author's transl)]. 197995555
field trials of slow-release formulations of chlorpyrifos and malathion for the control of chagas's disease vectors. 197995561
leiomyosarcoma of the inferior vena cava.the thirty-second case of leiomyosarcoma of the inferior vena cava and the twelfth resectable patient in the series is presented. a review of the literature demonstrates a marked female preponderance (5 to 1). the most common presenting symptom is right abdominal pain and a palpable mass. the different surgical problems generated by the involved segment of the cava are discussed. noteworthy is the high incidence of budd-chiari syndrome owing to hepatic vein obstruction with involvement of the up ...199895619
effect of neurotensin, substance p and morphine sulfate on the secretion of prolactin and growth hormone in the rat.neurotensin (nt), substance p (sp) and morphine sulfate (ms) elevate plasma prolactin and growth hormone levels in both normal or estrogen-progesterone pretreated male rats. by contrast, steroid priming is required for trf to exhibit prl-releasing activity. naloxone, an opiate receptor blocker, reverses the stimulatory effect of ms only. diphenhydramine, a histamine antagonist, inhibits the response to nt, sp and ms without affecting the response to trf. these results suggest the involvement of ...197795701
external cardiac compression. 199995737
binding of mouse peritoneal macrophages to tumour cells by a "lectin-like" macrophage receptor.a binding interaction is described between mouse peritoneal macrophages, tumour cells and proliferating mouse embryo fibroblasts. the interaction appears to be between a "lectin-like" receptor in the macrophage plasma membrane and carbohydrates in the plasma membrane of the target cells.197995806
[the proventriculus of the xenopsylla cheopis flea studied by scanning electron microscopy].the proventriculus of the flea x. cheopis was studied by means of scanning electron microscopy. the external surface of the proventriculus is a rigid structure with an alveolate surface ("wasp nest") formed by muscular cords. the internal surface of the proventriculus is represented by numerous acanthae which fall close together. they have a shape of bent dens with longitudinal sharply angular edges and concave spaces between them. some edges are crenate.197995815
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