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optimal dosage regimen for penicillins: bolus or continuous infusion? 1979115829
[profile of cefmetazole. ii. absorption, excretion, distribution and metabolism (author's transl)]. 1979115937
[microbiological studies on ozone sterilization in bioclean rooms (author's transl)]. 1979115943
[life of leprosy patients. 10. for the better days to come. (1)]. 1999116025
[examinations on the behaviour of grampositive and gramnegative bacteria on aluminium foil (author's transl)].the survival times of staph. aureus, strept. faecalis, e. coli, klebs. pneumoniae, ser. marcescens and p. aeruginosa were found out on aluminium foil. it was examined whether there exists a dependence on the initial colony count and in mixed cultures a mutual influence of the several species of bacteria. the longest survival times were found among the grampositive cocci. ser. marcescens and klebs. pneumoniae could no more be indicated after 19 days in case of initial colony count of log 7.0/cm2; ...1979116442
mammography in women with treated hypothyroidism. 1999116528
folacin deficiency and requirement in the squirrel monkey (saimiri sciuresus).acute folacin deficiency was studied in eight young squirrel monkeys (saimiri sciureus). half of the animals were fed a semipurified deficient diet (no added folic acid) and half were fed a control diet (0.84 mg of added folic acid per kilogram of dry diet). monkeys fed the deficient diet lost weight and suffered from diarrhea and dehydration leading to the death of one of the animals after 6 weeks. folacin deficiency also was studied in six older animals fed diets containing varying levels of a ...1979116540
acute acalculous cholecystitis: a complication of hyperalimentation.in a 5 year period, eight patients in whom acute acalculous cholecystitis developed during intravenous hyperalimentation are reviewed with emphasis on factors contributing to pathogenesis. gallbladder distention, biliary stasis, and bile inspissation, thought to be important in the pathogenesis of this disease, are enhanced with the use of hyperalimentation, and this potential complication is being seen with increasing frequency in seriously ill or injured patients who are being fed parenterally ...1999116561
[creutzfeldt-jakob. disease or syndrome]. 2002116587
competition of beta-lactam antibiotics for the penicillin-binding proteins of pseudomonas aeruginosa, enterobacter cloacae, klebsiella aerogenes, proteus rettgeri, and escherichia coli: comparison with antibacterial activity and effects upon bacterial morphology.the competition of a number of beta-lactam morphogenic probes for the penicillin-binding proteins (pbps) of pseudomonas aeruginosa, enterobacter cloacae, klebsiella aerogenes, proteus rettgeri, and escherichia coli has been studied. the results indicate that the various gram-negative bacteria have similar, but not identical, pbp patterns and that the individual proteins probably perform similar morphogenic functions as in e. coli k-12. comparison of the 50% binding concentrations of the compound ...1979116592
mineralization of the enamel of ovine permanent central incisor teeth using microhardness and histological techniques. 1979116728
3-[(1,2,3-thiadiazol-5-ylthio)methyl]cephalosporins.the syntheses of ten 3-](1,2,3-thiadiazol-5-ylthio)methyl]cephalosporins, made by displacement of the 3'-acetoxy group by the novel thiol derivatives, potassium 1,2,3-thiadiazole-5-thiolate and dipotassium 1,2,3-thiadiazole-4-carboxylate-5-thiolate, are described. several of the compounds showed good in vitro antibacterial activity against both gram-positive and gram-negative organisms. the subcutaneous in vivo activities against staphylococcus aureus were generally less than that of cafazolin. ...1979117106
[effect of inhibitory (mic) and subinhibitory concentrations of tobramycin on bacteriostatic and bactericidal activities of beta-lactam antibiotics (author's transl)]. 1979117156
[new nursing concepts in the 70's. 6. development of nursing as an independent profession. (2)]. 2002117183
[at the 50th supervisory nursing course in the cader school of zürich]. 2002117206
in vitro response to rosette inhibition factor (rif) and rosette restoring factor (rrf) of human lymphocyte after fractionation on a discontinuous density albumin gradient.in vitro studies on peripheral blood lymphocytes from tuberculous patients and healthy subjects are reported. factors isolated from human serum used in the experiments included the rosette inhibition factor (rif) from serum of tuberculous patients and the rosette restoring factor (rrf) from serum of healthy subjects. lymphocytes were fractionated on a discontinuous bsa gradient. lymphocytes from healthy subjects, sensitive to rif, as well as lymphocytes from tuberculous patients, sensitive to rr ...1979117785
benefit-cost and cost-effectiveness analysis: theory and application.benefit-cost analysis and cost-effectivensss analysis are terms used with increasing frequency by health planners and those concerned with review and evaluation of specific programs. the economic bases for these formal techniques are however often obscured by adaptations of convenience or misapplications of the concepts by biological scientists (and others). this paper reviews briefly the theory of benefit-cost analysis and its potential as a tool in choosing programs of optimum size, of maximum ...2002118068
isolation and characterization of recombinant dna plasmids carrying drosophila trna genes.recombinant plasmids carrying drosophila melanogaster trna genes were constructed by ligation of hindiii-cleaved drosophila dna to hindiii cut pbr322 dna. 90 clones were isolated that contained genes for one or more of eleven trnas. 43 of the plasmids were characterized by a number of methods: restriction nuclease digestion; agarose gel electrophoresis; hybridization with individual, purified, 125i-labelled drosophila trna molecules and in situ hybridization to drosophila chromosomes. the result ...1979118082
construction and characterization of e. coli promoter-probe plasmid vectors. i. cloning of promoter-containing dna fragments.derivatives of the escherichia coli drug-resistance plasmid pbr316 have been constructed which act as molecular probes for promoter-containing dna restriction fragments from various prokaryotic genomes. the plasmids, designated pbrh1 and pbrh3b, contain a unique ecori restriction site located within the promoter for the tetracycline resistance (tcr) gene. this site was created by the insertion of a chemically synthesized octanucleotide, containing the ecori cleavage sequence, into the hindiii si ...1979118083
protection against klebsiella pneumoniae respiratory tract infection of mice and squirrel monkeys given kanamycin by aerosol and injection.the methods of aerosol administration of kanamycin and im injection of the antibiotic were compared for their protection of mice and squirrel monkeys against klebsiella pneumoniae respiratory tract infection. mice exposed to ld90 of k pneumoniae at 0.5, 4, 24, 48 and 72 hours after they were treated with aerosol of kanamycin (27 mg/kg of body weight) were significantly better protected at all exposure times than were mice given the antibiotic (450 mg/kg) by im injection. squirrel monkeys given t ...1979118692
in vitro and in vivo laboratory studies on three hydroxyiminophenylacetyl cephalosporins with particular reference to sk&f 80303, an unusually long-acting cephalosporin.three cephalosporins with 7-(2-hydroxyiminophenylacetamido) side chains (sk&f 79433, 80000 and 80303), differing in their 3-substituents, exhibited similar broad-spectrum antibacterial activity in vitro against strains of staphylococcus aureus, streptococcus faecalis and various gram-negative bacilli. all three were active in vivo (s.c., mouse) against s. aureus, escherichia coli or klebsiella pneumoniae, but they differed significantly in serum pharmacokinetic profiles. sk&f 80303 produced high ...1979118958
growth of microorganisms in soybean oil emulsion and clinical implications. 1979119714
[analysis of suppurative pneumonia on the basis of our materials]. 1979119951
[antitetanus vaccination campaign in alsace. statistical study of the results]. 2002119997
[the importance of prophylactic, balneo-physiotherapeutic and recuperative treatment in the evolution of coxarthroses]. 2002120072
[treatment of colitis ulcerosa during pregnancy (author's transl)].aggressive pharmacotherapeutic and surgical measures are often contra-indicated in the treatment of colitis ulcerosa in pregnancy. especially in the sensitive embryonal development phase, the use of antibiotics, anti-inflammatory drugs, chemotherapeutics and acth is considered questionable. the subtotal colectomies and ileostomies often demanded in toxically dramatic colitides place a considerable burden on mother and foetus. a conservative therapeutic regimen, which has been successfully used i ...2002120087
mutational mosaicism and genetic counseling in retinoblastoma.mutations may arise throughout an organism's life cycle. typically, sporadic meiotic mutations give rise to individuals with all their germinal and somatic cells bearing the mutant gene. these mutations may be amorphs (with full penetrance and expressivity) or hypomorphs (with reduced penetrance and expressivity). mutational mosaicism, however, involves the origin of mutations occurring during mitosis, whether in the parent at some stage prior to reproductive maturity or in the offspring at some ...1979120116
trypanosoma (megatrypanum) amileari n. sp., isolated from oryzomys eliurus (wagner, 1845) (rodentia-cricetidae).a new species of trypanosome, trypanosoma (megatrypanum) amilcari, is described in the present paper. this new trypanosome was found in the circulating blood of a rodent species oryzomys eliurus (cricetidae). some biological observations were made.2002120124
[in vitro proliferative kinetics of chronic lymphocytic leukaemia lymphocytes (author's transl)]. 2002120288
[effect of enkephalin and morphine on gastric secretion and gastric blood flow]. 1979120296
in vitro microbiological evaluation of tei-1194 and tei-2012, novel antipseudomonal semisynthetic penicillins.tei-1194, sodium 6-[d-(-)-alpha-(coumarin-3-carboxamide)-phenylacetamide] penicillanate and tei-2012, sodium 6[d-(-)alpha-(8-hydroxy-coumarin-3-carboxamide)-phenylacetamide] penicillanate are new semisynthetic penicillin derivatives both possessing a broad spectrum of in vitro antibacterial activities. minimal inhibitory concentrations of both agents were compared with carbenicillin. tei-1194 and tei-2012 were clearly found to have more potent activities especially against pseudomonas aeruginosa ...1979120353
radiorespirometric analysis of glucose metabolism in the rat during feeding with 3'-methyl-4-(dimethylamino)azobenzene--radiorespirometry after partial hepatectomy.in previous papers we reported that the earlier peak time (pt) in radiorespiratory during feeding with 3'-methyl-4-(dimethylamino)azobenzene(3'-me-dab) is due to activation of the hexose monophosphate (hmp) pathway together with hepatic cell proliferation reflecting the toxic effects of this carcinogen. in this study, we investigated the correlation between the results of radiorespiratory and the levels of enzyme activities of hmp pathway in regenerating rat liver in connection with hepatic cell ...1979120561
[principles of rational infant nutrition. ii]. 2002120592
[value of assessment of plasma fsh, lh, and hcg in the prognosis of patients with malignant tumors of the testis]. 2002120613
immunization against experimental trypanosoma cruzi infection: inherent difficulties of a uniform comparative evaluation of antigenic preparations. 1979120626
the effect of lampit on trypanosoma cruzi in mice organs and in the bloodstream.mice infected with bloodstream forms of trypanosoma cruzi were treated with an active nitrofuran compound (nifurtimox, lampit). determination of the number of intracellular forms of t. cruzi in the liver and the spleen of control and lampit-treated mice showed that the drug induced a decrease in the number of parasites inside the cells. a decrease in the number of bloodstream forms was also observed. ultrastructural observations showed that lampit induces several alterations in t. cruzi, the mos ...1979120645
[morphological polysome analysis on bence jones protein myelomas with positive immunofluorescence for heavy chains (author's transl)]. 2002120667
[fabry's disease: diagnosis and therapeutic perspectives]. 2002120669
different measurements of thyroid function in hypothyroid infants diagnosed by screening.different measurements of thyroid function including i123 thyroid scanning were performed in 16 hypothyroid infants diagnosed by a tsh screening project. these results were then related to the clinical presentation and the bone age. although t3 levels were preferentially maintained, it was the best single measure of the severity of hypothyroidism. thyroglobulin may have a role in the diagnosis of athyrosis. scanning showed that athyrosis was uncommon (12.5%) but an ectopic gland occurred in 40%, ...2002120671
a new route to "bifunctional" chelating agents: conversion of amino acids to analogs of ethylenedinitrilotetraacetic acid. 2002120685
annotations on the measurement of liver ferritin, especially in the rat. 1979120687
[interpretation of the gingival inflammatory infiltrate].the investigation of tooth eruption in dermoid cysts of the ovary allows one to observe in the chorion at the level of the epithelial attachment, an anatomical component that seems to correspond to a local system of defense. up until now this has been considered to be a secondary inflammatory response resulting from the bacterial or mechanical assault. this component is found to form when the tooth erupts and constitutes an important element in the physico-pathogical process and of the immune re ...2002120787
[effect of an acute inflammatory process on anti-infectious resistance in mice].acute inflammatory reaction induced by intrapleural injection of calcium pyrophosphate increases the resistance of mice to klebsiella pneumoniae infection. transfer to mice of protection against klebsiella pneumoniae is effected by injection of inflammation sera.1979121260
effects of alcohol abuse on progression of liver disease in methadone-maintained patients. 1998121359
the ultrastructural features of laser trabeculopuncture and cyclodialysis. problems related to successful treatment of chronic simple glaucoma.microexplosions induced by a q-switched nd:glass laser working above optical breakdown power density levels are able to destroy the inner wall of schlemm's canal and to tear open both the supraciliary and suprachoroidal space. furthermore, the ciliary muscles bundles may be disrupted, becoming subsequently permeable to the aqueous and thus also acting as a new outflow route. however, whereas breaks of the inner wall of schlemm's canals are sealed in the monkey by the activity of endothelial cell ...1979121373
the effect of prophylactic tinidazole on the anaerobic vaginal flora in patients undergoing gynaecological surgery.the effects of prophylactic tinidazole on the vaginal carrier state of anaerobic bacteria and the development of postoperative infections were studied in 50 patients undergoing gynaecological surgery. the results are based on a double-blind trial, using tinidazole (fasigyn; pfizer) and placebo. although no postoperative infections other than urinary tract infections were observed in our series, this study shows conclusively that the isolation of anerobic bacteria from the vagina decreased marked ...1979121639
[observations on antibacterial activity of thiamphenicol glycinate acetylcysteinate (author's transl)].in vitro thiamphenicol antibacterial activity in the presence of n-acetylcysteine as sodium salt proved to be enhanced when compared with that of the antibacterial alone against both gram-positive and gram-negative bacterial strains. the in vitro results were confirmed in vivo in the guinea-pig, where the sera from animals previously treated by i.m. route with thiamphenicol glycinate acetylcysteinate, showed a higher antibacterial activity than sera from animals treated with thiamphenicol glycin ...1979122158
[toxic bacillary dysentery and amaurosis (author's transl)]. 2002122214
[modern surgical opinions concerning esophageal diverticula]. 2002122232
bacteriological and histopathological estimation of aerodin efficacy administered by respiratory way to mice and guinea pigs experimentally infected. 1979122262
transient trh deficiency after prolonged thyroid hormone therapy.a patient who had been treated with large doses of thyroid hormone for several years developed features of secondary hypothyroidism after thyroid hormone withdrawal. these findings were low serum t4 (3.8 micrograms/dl), t3 (23 ng/dl), and a failure of serum tsh to rise after trh injection. serum prl values rose normally after trh administration, and evaluation of other pituitary hormones was normal. when retested 3 months later, at which time the serum t4 was 5.5 micrograms/dl, the patient was s ...1978122410
in vitro activity of piperacillin, a new semisynthetic penicillin with an unusually broad spectrum of activity.the in vitro activity of piperacillin (t-1220), a new semisynthetic derivative of aminobenzylpenicillin, was investigated. the majority of streptococci and pneumococci were inhibited by 0.12 micrograms/ml; the staphylococci and enterococci were inhibited by 2 micrograms/ml. piperacillin was slightly more active against neisseria and haemophilus influenzae than was ampicillin. piperacillin was active against all members of the enterobacteriaceae including the klebsiella, 58% of which were inhibit ...1978122518
computed tomography in non-tumoral paediatric neuroradiology. 2002122730
primary hepatic intra-abdominal hemangiopericytoma. 2002122823
reduction products of spectinomycin.the two epimers of dihydrospectinomycin have been separated and identified structurally. four tetrahydrospectinomycins have also been prepared.1975123237
deaf students with other disabilities. 2002123697
successful treatment of transection of aortic arch and innominate artery.a patient was seen with a widened mediastinum following rapid deceleration injury. a retograde angiogram showed rupture of the transverse aortic arch and occlusion of the origin of the innominate artery. at operation cardiopulmonary bypass with systemic, cerebral, and myocardial preservation were used to provide a safe approach for inserting a graft to successfully restore normal circulation.2002123737
inhibitory effect of normal mammalian sera on the rosette formation of human lymphocytes with sheep red blood cells. 1975123840
[localization of allergic contact eczema as an indication of the causing agent]. 2002123883
[ 3 osteomas of mastoid localization]. 2002123942
6-phosphogluconate dehydrogenase from neurospora crassa. 2002124005
[frequency and combination of structural dysharmonias in relation to dysgnathia and therapy]. 2002124118
new chromosomal syndromes. 1975124130
[saltykov's carcinoids on down's syndrome. description of two cases (author's transl)]. 2002124229
[exact and approximate diagnosis in laparoscopy]. 2002124405
[direct carotid-vertebral anastomosis supplying blood collaterally in subclavian occlusion (author's transl)].the anastomosis between the vertebral artery and occipital artery in case of proximal subclavian artery occlusion is demonstrated. the reasons for development and angiographic visibility of this channel are discussed.1998124678
["masked" supra-renal tumour (author's transl)].for the diagnosis of supra-renal tumours or tumours of supra-renal rests, it is necessary to employ all available radiological methods as well as the clinical data. two cases are described in which a supra-renal tumour had been "masked" and found at operation. in the first case a cyst in the tail of the pancreas had been considered, in the second, a tumour of the renal hilum or ureter had been diagnosed. it is concluded that in the differential diagnosis of a cyst of the tail of the pancreas, su ...1998124685
effect of p-chlorophenylalanine on the central nervous excitability threshold and on the activity of some central depressants.the effect of p-chlorophenylalaine (pcpa)on the central nervous excitability threshold for the neurostimulants pentetrazol, picrotoxin and strychnine inflused intravenously was evaluated in male albino mice. the effect of pcpa pretreatment was also studied in mice treated both with the neurostimulants and with central depressants meta-tolylcarbamide (mtc), phenacemide (phenylacetylurea, phenurone) or phenobarbitol sodium (pbs). pcpa applied alone or together with mtc, phenacemide and pbs lowered ...1998124805
teaching the handicapped child to learn. 1998124811
traumatic shock monitored by doppler ultrasonic flowmeter. case report. 1998124813
the mutagenicity of azathioprine in mice, drosophila melanogaster and neurospora crassa.the chemotherapeutic coumpound azathioprine was tested for possible mutagenicity in swiss albino mice, drosophila melanogaster and neurospora crassa. utilizing the dominant-lethal assay it was found that acute oral doses of azathioprine (2 times 25 mg/kg body weight), induced dominant-lethal mutations in mouse spermatocytes. chronic oral doses of azathioprine (2 times 25 mg/kg body weight/week for 10 weeks) resulted in a greater rate of dominant-lethality. this increase was not permanent, and by ...1975124817
[theoretical bases of thrombolytic therapy].purified streptokinase has in vitro a double biochemical activity on plasminogen. at a low molecular ratio of streptokinase/plasminogen, mainly plasmin is generated. at an equimolar streptokinase-plasminogen ratio, mainly a complex streptokinase-plasmin is formed. this complex has a low proteolytic activity but has a high activator activity on plasminogen and maintains esterolytic properties. it is likely that the reactions occurring in vitro with purified reagents also occur in vivo, the situat ...1998124849
soluble and particulate glycolysis in developing castor bean endosperm. 2001125088
papillon-lefèvre syndrome. 2002125316
effects of corticosteroid treatment and inflammation on the cellular content of blood and exudate in mice.inflammatory exudates have been produced in mice by intraperitoneal injection of thioglycollate broth 24 hr and again 3 hr before collecting of the exudate. the first injection of broth exerts a "priming" effect leading to an enhanced response to the second injection. by this procedure more than 30 x 106 leucocytes of which 78 per cent. were polymorphs were obtained from each mouse. administration of paramethasone reduced the number of cells in the exudate when given at the same time as broth bu ...1975125317
xanthine, hypoxanthine and muscle pain. histochemical and biochemical observations.a suspected case of xanthine oxidase deficiency has been further investigated. the patient complained of arthralgia and myalgia. further studies included histochemical and ultramicroscopic analysis of muscle sarcoplasmic reticulum, and biochemical studies. high levels of xanthine and hypoxanthine were found, while uric acid was absent in the muscle extracts.2001125457
separation of subfragment-1 isoenzymes from rabbit skeletal muscle myosin. 1975125854
["the social psychiatric care--aussenfürsorge--of the mental hospital of erlangen" (author's transl)]. 2002126394
cytogenetics and the pathologist. 1975126409
[psychological aspects on genetic counseling]. 2002126413
superannuation-1. swindle or bargain? 2002126445
[observations on the combination of iga-deficiency and extremely low antibody titers against measles (author's transl)]. 1975126541
poncimarin, a new coumarin from poncirus trifoliata l.a new coumarinic derivative (poncimarin; c19h22o5; m.p. 140 c degrees) was isolated from unripe fruits of poncircus trifoliata l. which from spectroscopic evidences was formulated as 7-(2,3-epoxy-3-methyl butyloxy)-8-(2,3-epoxy-3-methyl butyl) coumarin.2002126585
[plasma transport of 5-hydroxytryptamine-3h. ii. identification of the carrier protein of 5-hydroxyindoleacetic acid].in the first note, we have demonstrated a 5-hydroxyindole acetic acid binding to plasma proteins. by gel filtration on sephadex g 200 and polyacrylamide gel electrophoresis, the 5-hydroxyindole acetic acid carrier protein was identified to serum-albumin.1975126777
fine structure of the spermatheca of the mealworm beetle (tenebrio molitor l.).the spermatheca of the female mealworm beetle is an inflorescence of branching cuticular ducts which is connected to the bursa copulatrix via a cuticular neck surrounded by a muscular coat. the infolded bursal cuticle consists of a distinct outer epicuticle, inner epicuticle, procuticle, and a subcuticular zone; the latter is rich in mucopolysaccharides. the cuticle of the neck lacks a distinct procuticle. the cuticle of the spermatheca itself is mostly inner epicuticle with two thin underlying ...2002126805
comparative ultrastructure and blood-brain barrier in diapause and nondiapause larvae of the european corn borer ostrinia nubilalis (hübner).ultrastructural examination of diapause and nondiapause larval brains of the european corn borer disclosed anatomical differences that may be related to the insect's "blood-barrier". the perineurial type i cells are quite closely appressed in the diapause brain, but thrown into extensive folds with large intercellular spaces in the nondiapause brain. the perineurial type ii cells of diapause and nondiapause larvae are basically similar in general ultrastructure, and most likely form the basis fo ...1975126807
an ultrastructural study of neuromuscular spindles in normal mice: with reference to mice and man infected with mycobacterium leprae.mycobacterium leprae have been found within muscle spindles in mice, using electron microscopy, and in man, using light microscopy. their mode of entry clearly is important. it may be via capsular cells, capillaries or nerves. for this reason muscle spindles from normal mice were studied by electron microscopy with special reference to the capsule and the relationship of it with capillaries and nerves, as well as details of the intrafusal fibres and capsular space. a fenestrated capillary was fo ...1975126981
design of living environments for nursing-home residents: increasing participation in recreation activities.nursing-home residents have frequently been characterized as unoccupied and disengaged. at the outset of the present study, most residents were to be found in their own rooms, not exhibiting gross motor behavior or social interaction, and not participating in appropriate activities. to modify residents' levels of participation with the environment, a manipulative area was provided in the lounge. participation in the lounge averaged 20% on days when the activity was not available, but increased t ...2002126983
diseases of the prostate: an outline to diagnosis and treatment. 2002126986
characterization of 5.8s ribosomal ribonucleic acid in neurospora crassa.neurospora crassa ribosomes contain a species of ribonucleic acid (rna) of molecular weight 54,000, similar to 5.8s ribosomal rna previously described for other eukaryotic organisms. the 5.8s rna from n. crassa was found to be released by heat treatment at 60 c from 25s ribosomal rna but not from 18s ribosomal rna. the base composition of n. crassa 5.8s rna was similar to that of 5.8s rna from saccharomyces cerevisiae, but differed from animal 5.8s rna. during the course of this study, it was di ...1975126993
antigens of leptotrichia buccalis i. their serologic reaction with human sera. 1975127031
mitral valve disease associated with tracheal tug and ortner's syndrome. 2002127047
[use of enteroseptol in out-patient surgery for treatment of suppurative processes]. 2002127067
steroid sulphates in human adult testicular steroid synthesis. 1975127080
new mineralcorticoids in the syndrome of low-renin essential hypertension. 2002127083
interaction of homogeneous mitochondrial atpase from rat liver with adenine nucleotides and inorganic phosphate.mitochondrial atpase from rat liver mitochondria contains multiple nucleotide binding sites. at low concentrations adp binds with high affinity (1 mole/mole atpase, kd = 1-2 mum). at high concentrations, adp inhibits atp hydrolysis presumably by competing with atp for the active site (ki = 240-300 mum). as isolated, mitochondrial atpase contains between 0.6 and 2.5 moles atp/mole atpase. this "tightly bound" atp can be removed by repeated precipitations with ammonium sulfate without altering hyd ...1975127085
purification and properties of membrane-bound coupling factor-latent atpase from mycobacterium phlei.the membrane bound coupling factor-latent atpase was solubilized from the membrane vesicles of mycobacterium phlei by using 0.25 m sucrose or low ionic strength buffer. purification of the solubilized enzyme by use of sepharose-adp conjugate gel yielded a homogenous preparation of latent atpase which was purified about 216-fold in a single step with an 84% yield. the enzyme exhibits a specific activity of 39 mumoles of atp hydrolyzed per min per mg protein. the purified enzyme exhibits coupling ...1975127086
impaired cell-mediated immunity in patients with cancer.the ability of peripheral blood lymphocytes to respond in vitro to phytohemagglutinin (pha) and to allogeneic cells in mixed leukocyte reaction (mlc) was studied in 85 patients with cancer and in 50 healthy controls. the effect produced by sera from cancer patients on in vitro lymphocyte blastogenesis was tested on autologous cells and on homologous cells from a constant panel of 10 normal volunteers. patients with cancer showed a distinct deficiency of cellular immune responsiveness reflected i ...2002127091
adolescents on the surface. common dermatologic problems. 2002127095
[nickel eczema]. 2002127096
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