| [significance of the rate of isolation of klebsiella, enterobacter, citrobacter and intestinal yersinia in bacteriological research]. | | 1987 | 3630485 |
| in-vitro activity of ticarcillin with and without clavulanic acid against clinical isolates of gram-positive and gram-negative bacteria. | the in-vitro activity of ticarcillin with and without clavulanic acid was investigated against 285 freshly isolated clinical strains of gram-positive and gram-negative bacteria by the agar-dilution technique on mueller-hinton-agar. clavulanic acid had an excellent or moderate potentiating effect on the in-vitro activity of ticarcillin against staphylococci, escherichia coli, klebsiella spp., enterobacter aerogenes, proteus mirabilis, citrobacter spp., acinetobacter, haemophilus influenzae and ba ... | 1986 | 3636325 |
| susceptibility of ticarcillin-resistant gram-negative bacilli to different combinations of ticarcillin and clavulanic acid. | the susceptibility of ticarcillin-resistant and of ticarcillin-susceptible gram-negative bacilli to different combinations of ticarcillin and clavulanic acid has been investigated. susceptibility to ticarcillin has been restored in ticarcillin-resistant isolates in proportion to the amount of clavulanic acid in the combination and depending upon the species. the decrease in the mics of ticarcillin was excellent to good in proteus, morganella, providencia, escherichia coli and klebsiella, moderat ... | 1986 | 3636338 |
| o-nitrophenyl-beta-d-galactopyranoside-urease-indole broth, a new composite tube medium for salmonella screening. | a new composite broth medium combining o-nitrophenyl-beta-d-galactopyranoside (onpg) and urease and indole tests in a single tube is described. high-level agreement with individual conventional tests was recorded in comparative studies with 2,412 cultures of members of the family enterobacteriaceae, i.e., 100% agreement with the exception of hafnia spp. (96.3% agreement) for the onpg test and citrobacter, enterobacter, and hafnia spp. (75, 86.4, and 98.2% agreement, respectively) for the urease ... | 1986 | 3639886 |
| [practical recommendations for examining the pulmonary pleura of fetuses and newborn infants using contact microscopy]. | it has been found that the pleura visceralis of fetuses and neonates is consistently involved in inflammatory processes occurring in pneumonias caused by gram-negative organisms (citrobacter sp., escherichia coli, klebsiella sp., serratia marcescens) and may display signs of infection when the pneumonia is not yet apparent. this property of the pleura as a filtration membrane may help the pathologist in the early diagnosis of infectious disorders in neonates. recommendations are given on the exc ... | 1987 | 3662866 |
| in vitro antimicrobial activity of cefpirome, a new cephalosporin with a broad antimicrobial spectrum. | the in vitro activity of cefpirome (hr 810), a new cephalosporin antibiotic having a 2,3-cyclopentenopyridine group in the 3-position side chain, was compared with in vitro activities of 5 other cephalosporins. hr 810 showed a broad spectrum of antimicrobial activity against gram-positive and gram-negative bacteria when tested using 71 standard strains and 876 clinical isolates. hr 810 inhibited 70% of the clinically isolated staphylococcus aureus and staphylococcus epidermidis strains when used ... | 1987 | 3669290 |
| vi capsular polysaccharide-protein conjugates for prevention of typhoid fever. preparation, characterization, and immunogenicity in laboratory animals. | the vi has proven to be a protective antigen in two double masked, controlled clinical trials in areas with high rates of typhoid fever (approximately 1% per annum). in both studies the protective efficacy of the vi was approximately 70%. approximately 75% of subjects in these areas responded with a fourfold or greater rise of serum vi antibodies. in contrast, the vi elicited a fourfold or greater rise in 95-100% of young adults in france and the united states. methods were devised, therefore, t ... | 1987 | 3681191 |
| citrobacter freundii endocarditis in an intravenous drug abuser. | we have reported the third case of citrobacter endocarditis. echocardiograms were invaluable in establishing the diagnosis. ours is the first reported case of citrobacter endocarditis to be cured by antimicrobial therapy alone. | 1987 | 3686149 |
| transamination catalysed by tyrosine phenol-lyase from citrobacter intermedius. | the interactions of tyrosine phenol-lyase with its substrates: l-tyrosine and l-serine, and the competitive inhibitors: l-alanine, l-phenylalanine, l-m-tyrosine, were studied. it was demonstrated that the enzyme catalyzed a half-transamination reaction between substrates or inhibitors and the protein-bound pyridoxal phosphate. the products of this side-reaction, pyridoxamine phosphate and the respective keto acids, were identified. the kinetic parameters were determined for beta-elimination of l ... | 1987 | 3691524 |
| [effect of norfloxacin on bacterial flora in human feces]. | norfloxacin (nflx), a synthetic oral antibacterial agent of quinolone carboxylic acid, was given orally for 5 full days at a dose of 200 mg, three times daily after each meal to healthy normal men with ages between 22 and 25 years weighing 53.0 to 84.0 kg (average 67.0 kg). the actual regimen followed was that the drug was administered twice after lunch and supper on the first day of dosing, and once after breakfast on the last day of dosing. on the 5th day before the start of dosing, on the fir ... | 1987 | 3694785 |
| in vitro activity of a new broad spectrum, beta-lactamase-stable oral cephalosporin, cefixime. | cefixime is a new orally absorbed iminomethoxy, aminothiazolyl cephalosporin. it inhibits the majority, 90%, of streptococcus pneumoniae, streptococcus pyogenes, branhamella catarrhalis, haemophilus influenzae, escherichia coli, klebsiella pneumoniae, proteus mirabilis and neisseria gonorrhoeae at concentrations less than or equal to 0.25 micrograms/ml. it inhibits 90% of the other members of the enterobacteriaceae at concentrations less than 1 microgram/ml, with the exception of some strains of ... | 1987 | 3696836 |
| [effect of s6472 and cefaclor on bacterial flora in adult human feces]. | s6472 is a mixture of cefaclor (ccl) granules with gastric-soluble coating and those with enteric-soluble coating at the ratio (in potency) of 4 to 6. with administration of this formulation, a prolonged blood level of ccl is obtained. s6472 and ccl were administered orally to 19 healthy male volunteers between 20 and 27 years of age (mean: 23 years) weighing between 51 and 80 kg (mean: 64.7 kg). four subjects were given 2 capsules and 5 subjects were given 4 capsules each containing 187.5 mg of ... | 1986 | 3702058 |
| [meningitis and brain abscess caused by levinea malonatica in a newborn infant]. | | 1986 | 3707283 |
| infantile maxillary osteomyelitis with cerebral abscess. | | 1986 | 3723299 |
| in vitro activity of ci-934, a new quinolone, compared with that of other quinolones and other antimicrobial agents. | the in vitro activity of ci-934, a new 4-quinolone, was determined against gram-positive and gram-negative bacteria. the mics for 90% of the isolates tested were 0.25 microgram/ml for streptococcus pneumoniae, 0.5 microgram/ml for streptococcus faecalis, 0.25 microgram/ml for staphylococci, including methicillin-resistant strains, and less than or equal to 1.0 microgram/ml for escherichia coli, salmonella and shigella spp., klebsiella spp., proteus spp., and citrobacter spp. ci-934 had activity ... | 1986 | 3729343 |
| in vitro activity of ro 15-8074 and ro 19-5247, two orally administered cephalosporin metabolites. | the activity of two iminomethoxy aminothiazoly cephalosporins, ro 15-8074 and ro 19-5247, was compared with that of other beta-lactams against a total of 491 bacterial strains. both were highly active (mic for 90% of the strains tested [mic 90], less than or equal to 2 micrograms/ml) against the majority of the members of the family enterobacteriaceae, haemophilus influenzae, neisseria spp., and streptococcus pneumoniae, being at least 16-fold more active than cephalexin and 8-fold more active t ... | 1986 | 3729361 |
| salmonellae and other enteropathogenic bacteria in the intestines of wall geckos in nigeria. | the aerobic bacterial flora of the intestine of 150 wall geckos (hemidactylus brookei) was investigated. a variety of bacteria was recovered including 35 isolates of salmonella and several other species of enterobacteriaceae, viz. shigella sonnei - 2, edwardsiella tarda - 4, enterobacter spp - 8, citrobacter freudii - 3, serratia marcescens - 3, proteus spp - 35, klebsiella pneumoniae - 13, and escherichia coli - 17, isolates. eight salmonella serotypes were identified, the predominant ones bein ... | 1986 | 3729372 |
| [neonatal sepsis and urinary tract infection due to citrobacter diversus]. | | 1986 | 3732947 |
| molecular epidemiology of neonatal meningitis due to citrobacter diversus: a study of isolates from hospitals in maryland. | six cases of neonatal meningitis due to citrobacter diversus were diagnosed in three baltimore (maryland) hospitals between 1983 and 1985. using plasmid profiles, biotypes, serotypes, and chromosomal restriction endonuclease digests as epidemiological markers, we studied 63 isolates of c. diversus (including four isolates from cerebrospinal fluid) from these and seven other hospitals in maryland. within two of the three hospitals with meningitis cases, the same strain of c. diversus was isolated ... | 1986 | 3734491 |
| [effect of cefminox on bacterial flora in human adult feces]. | cefminox (cmnx), a new cephamycin, was administered by one shot intravenous injection twice daily with a dose of 1,000 mg each time for 5 days to seven healthy male volunteers whose ages ranged from 21 to 28 years (mean: 25 years) and body weights were from 60 to 92 kg mean: 72 kg). the effect of the drug on fecal bacterial flora was investigated and the concentrations of the drug in feces were measured on 5th day before the treatment, on 0, 3rd, and 5th day (the final day of the treatment) duri ... | 1986 | 3761549 |
| [treatment of urologic infections with cefamandole (pharmachim)--the microbiological and clinical results]. | the authors study the possibilities of cephalosporin antibiotic cefamandol, new for our clinical practice, in the treatment of uroinfections. the microbiological study on a total of 2301 bacterial strains, isolated from patients with uroinfections, reveals that cefamandol excels in its action against gram-positive microorganisms, all beta-lactam antibiotics, used in our country. as regards e. coli, citrobacter, klebsiella, enterobacter, p. mirabilis and indole positive pro cefamandol is better t ... | 1986 | 3765588 |
| novobiocin-brilliant green-glucose agar: new medium for isolation of salmonellae. | a new medium, called novobiocin-brilliant green-glucose (nbg) agar, was developed for the isolation of salmonella spp. and evaluated against other conventionally used media including bismuth sulfite, xylose-lysine decarboxylase, brilliant green-sulfa, hektoen enteric, and salmonella-shigella agars. nbg had recovery rates comparable to the other enteric media tested with pure cultures as well as with naturally contaminated amphibian and reptile waters and fecal specimens. however, nbg, hektoen en ... | 1986 | 3767359 |
| ultrasonic irradiation of bacterial polysaccharides. characterization of the depolymerized products and some applications of the process. | ultrasonic irradiation (u.i.) has been used to depolymerize biopolymers including dna, dextran, and the vi capsular polysaccharide from citrobacter freundii. representative bacterial polysaccharides were subjected to u.i. and the effect of this energy upon their molecular weight and chemical structure was characterized. u.i. depolymerized a neutral polysaccharide (dextran) and acidic polysaccharides containing either a phosphoric diester linkage [haemophilus influenzae type b (hib) and pneumococ ... | 1986 | 3768916 |
| comparative "in vitro" activity of ciprofloxacin (bay o9867) and other antimicrobial agents against urinary bacterial isolates. | ciprofloxacin (bay o9867) is a new quinolone derivative. its activity against 537 urinary bacterial isolates was compared with those of ampicillin, amikacin, carbenicillin, cefazolin, cefotaxime, cefoxitin, ceftazidime, nalidixic and oxolinic acids, norfloxacin, trimethoprim, and other antimicrobial agents, when appropriate. it inhibited 90% of citrobacter freundii, enterobacter spp., e. coli, klebsiella spp., proteus spp., and serratia spp. at 0.78 microgram/ml. the majority of pseudomonas aeru ... | 1986 | 3769047 |
| occurrence and clinical significance of tyrosine clearing positive citrobacter freundii in human faecal specimens. | 59 tyrosine clearing positive citrobacter strains were isolated from a total of 2062 human faecal specimens, specifically from 1167 healthy people and from 895 patients suffering from different gastrointestinal syndromes. all strains were identified biochemically as citrobacter freundii. citrobacter diversus 100% positive for tyrosine clearing could not be isolated in any case. citrobacter freundii was found twice as frequently in stools of healthy human beings than of patients. there is a stati ... | 1986 | 3788353 |
| multiple drug-resistant citrobacter freundii infection mimicking typhoid fever. | | 1986 | 3791397 |
| use of aztreonam in patients suffering from urinary tract infections with contraindications for the use of aminoglycosides. | the clinical efficacy and safety of aztreonam were studied in 30 patients suffering from urinary tract infections caused by gram-negative bacteria. aztreonam was given in a dose of 1 g i.m. at intervals of 12 or 24 hours. duration of therapy was 2-8 days. bacteria isolated in urine cultures were: escherichia coli (60%); proteus mirabilis (10%); pseudomonas aeruginosa and citrobacter sp. (7%); proteus vulgaris, serratia marcescens; klebsiella pneumoniae and pseudomonas species (3%). at completion ... | 1986 | 3791478 |
| structure determination of the o-specific polysaccharides from citrobacter o4- and o27-lipopolysaccharides by methylation analysis and one- and two-dimensional 1h-nmr spectroscopy. | using sugar and methylation analyses, and one- and two-dimensional 1h-nmr spectroscopy at 500 mhz it was established that poly-beta-1,2-4-deoxy-d-arabinohexopyranose occurs as o-specific chains of lipopolysaccharides in citrobacter serotypes o4, o27 and o36. strong serological cross-reactivity between these serotypes is in full agreement with the chemical identity of their o-specific polysaccharides. | 1987 | 3803596 |
| [clinico-pathogenetic basis for using crystalline lysozyme in the combined therapy of food toxinfections]. | in food toxinfections caused by various microorganisms (staphylococcus, escherichia, klebsiella, proteus, citrobacter, etc.) a decrease of lysozyme debit and an increase of ph of gastric juice were found. one third of patients exhibited lactose deficiency of the small intestine. treatment with furazolidone contributed to the development of lactase deficit and delayed stools normalization. crystalline lysozyme shortened duration of febrile reaction and diarrhea, its intake facilitated lactose hyd ... | 1986 | 3817153 |
| rapid catalase supplemental test for identification of members of the family enterobacteriaceae. | a simple, rapid, semiquantitative slide catalase test useful for differentiating members of the family enterobacteriaceae is described. judging by the time required for appearance of oxygen bubbles in 3% hydrogen peroxide, the immediate catalase reactors were yersinia, serratia, proteus, morganella, providencia, cedecea, and hafnia spp. the delayed catalase reactors were escherichia, shigella, klebsiella, enterobacter, salmonella, citrobacter, edwardsiella, kluyvera, and tatumella spp. this info ... | 1987 | 3818934 |
| outbreak of neonatal citrobacter diversus meningitis in a suburban hospital. | between february and june, 1983, four cases of citrobacter diversus neonatal meningitis were identified at a suburban baltimore hospital. one of the 4 infants died at age 13 months, 2 (both of whom had brain abscesses) have evidence of developmental delay and 1 appears to be normal after 33 months of follow-up. a review of microbiology records revealed that c. diversus had been present in the hospital nursery prior to identification of the first infant with meningitis, with isolation from infant ... | 1987 | 3822617 |
| [ability of citrobacter freundii strains isolated in acute intestinal infections to produce lt-enterotoxin]. | c. freundii enteropathogenic strains were found to be capable of producing choleroform thermolabile enterotoxin. thus, in the study of 96 c. freundii strains 38 enterotoxin-producing cultures (39.5%) were revealed by means of the molecular-biological techniques and 29 such cultures (30.0%), by means of the radioimmunoassay (ria). 100% coincidence was noted in the results of tests for enterotoxigenicity, made by means of ria or hybridization techniques with the use of the lt-probe containing a cl ... | 1986 | 3825350 |
| [gram-negative bacteria resistant to antibiotics in foods]. | from 154 food samples, including vegetables (lettuce), milk and meals served at school it was possible to isolate and identify 400 gram negative bacilli distributed among 339 enteric bacteria (escherichia, shigella, citrobacter, klebsiella, enterobacter, serratia and proteus) and other 61 non enteric bacilli (acinetobacter, flavobacterium, aeromonas and pseudomonas). submitting this cultures to the drugs sulfadiazine (su), streptomycin (sm), tetracycline (tc), chloramphenicol (cm), kanamycin (km ... | 1985 | 3837834 |
| temocillin. in vitro antibacterial activity. | temocillin, a 6-alpha-methoxy penicillin derivative, was tested in vitro against 516 recent clinical isolates of enterobacteriaceae. the compound exhibited good antibacterial activity, with 95% of isolates inhibited by a range 2 to 16 mg/l. further studies, against selected isolates resistant to ticarcillin, piperacillin and cefuroxime (klebsiella oxytoca, 25; enterobacter species, 34; and citrobacter species, 5), showed about half of the isolates of k. oxytoca (11/25) to be resistant to aztreon ... | 1985 | 3849425 |
| comparative activity of the penem antibiotic sch 34343 against gram-negative and gram-positive bacteria with special reference to multiresistant strains. | a new penem antibiotic, sch 34343, was shown to be active against a large number of gram-positive bacteria. the drug inhibited penicillinase-positive and -negative staphylococci equally well, being five times more active than cefamandole and ten times more active than methicillin. most methicillin-resistant staphylococci were inhibited by concentrations between 0.25 and 4 mg/l, but a small group of highly resistant strains were observed. sch 34343 was eight times less active than ampicillin and ... | 1985 | 3849537 |
| [effects of ks-r1 (ampicillin suppository) and ampicillin oral dosing on fecal flora of children]. | a newly developed product, ks-r1 (a suppository containing 250 mg potency of ampicillin (abpc)), was given to 7 children (5 boys and 2 girls) ranging from 4 years and 5 months to 8 years and 10 months in age, 3 times a day (average daily dose, 62.4 mg/kg) for 5 days. as a control, the same amount of abpc dry syrup was given orally to 7 children (4 boys and 3 girls) ranging from 2 years and 8 months to 7 years and 7 months in age, 3 times a day (average daily dose, 55.3 mg/kg) for 5 days. the eff ... | 1985 | 3849603 |
| [clinical and experimental studies on the pathogenicity of clinical isolated citrobacter freundii]. | clinical and fundamental studies were performed using citrobacter freundii isolated from urine specimens of in- and out-patients between january 1980 and july 1981. the c. freundii (greater than 10(4)/ml) isolated from urine was closely related to chronic complicated urinary tract infection. mics of pyridonecarbonic acids (enx, oflx and nflx) and cmx against c. freundii were low. pyridonecarbonic acids (enx, oflx and nflx) and cmx showed good therapeutic effects against the experimental ascendin ... | 1985 | 3851621 |
| timentin in the treatment of symptomatic complicated urinary tract infections in adult patients. | the safety and effectiveness of timentin were evaluated in 34 adult patients with symptomatic complicated urinary tract infections, principally due to multiply-drug-resistant bacteria. although a wide variety of organisms, particularly gram-negative bacilli, were found, escherichia coli was the most frequent, accounting for 14 of 45 (31 percent) pathogens isolated. ten (22 percent) isolates were pseudomonas aeruginosa; 11 (24 percent) were proteus or morganella species; three (7 percent) were ci ... | 1985 | 3852637 |
| mezlocillin, ceftizoxime, and amikacin alone and in combination against six enterobacteriaceae in a neutropenic site in rabbits. | closed-space, locally neutropaenic infection sites were simulated in rabbits by implanting subcutaneous semipermeable chambers inoculated with 5 x 10(4) cfu/ml of escherichia coli (one strain), citrobacter diversus (one strain), klebsiella pneumoniae (two strains) or serratia marcescens (two strains). four hours after inoculation, treatment was begun with amikacin (15 mg/kg), mezlocillin (100 mg/kg), or ceftizoxime (50 mg/kg) alone or in two-drug combinations. antibiotics were given intramuscula ... | 1985 | 3856563 |
| in vitro antibacterial activity of bmy-28142, a new extended-spectrum cephalosporin. | the in vitro activity of bmy-28142 was compared with that of cefotaxime, ceftazidime, moxalactam, and imipenem against 639 clinical isolates and a number of in vitro-selected resistant mutants. bmy-28142 was the most potent compound against the members of the family enterobacteriaceae with a mic for 90% of the strains of 0.12 micrograms/ml. the activity against pseudomonas aeruginosa was comparable to that of ceftazidime and imipenem. strains of staphylococci were moderately susceptible to bmy-2 ... | 1985 | 3859244 |
| [evaluation of ceftizoxime in the treatment of respiratory tract infections]. | ceftizoxime (czx) was used for 33 patients with respiratory tract infections; 22 patients with pneumonia, 3 patients with pulmonary abscess, 4 patients with diffuse panbronchiolitis and 4 patients with acute exacerbation of bronchiectasia. clinical effects of czx were evaluated in 33 patients; excellent in 16 and good in 14 patients. the efficacy rate was 91%. bacteriological effects of czx were prominent in 7 patients infected with s. pneumoniae, h. influenzae, k. pneumoniae and citrobacter, bu ... | 1985 | 3861881 |
| in-vitro activity of ofloxacin, a quinolone carboxylic acid compared to other quinolones and other antimicrobial agents. | ofloxacin is a new quinolone carboxylic acid compound. its activity against 900 bacterial isolates was determined. it inhibited 90% of escherichia coli, klebsiella sp., aeromonas hydrophila, salmonella spp., shigella spp., citrobacter spp., enterobacter spp., morganella morganii, proteus mirabilis, yersinia enterocolitica at less than or equal to 0.8 mg/l. branhamella catarrhalis, haemophilus sp., neisseria sp. were inhibited by less than or equal to 0.1 mg/l. pseudomonas aeruginosa and other ps ... | 1985 | 3865923 |
| conversion of cloxacillin into a progressive inhibitor of beta-lactamases by sulfonation and its activity against various types of these enzymes. | on the assumption of the theory that the sulfone of a penam derivative should effectively act as a suicide substrate against beta-lactamases to which the parent compound is a poor substrate, the action of cloxacillin sulfone on four different types of beta-lactamases was studied. as we expected, cloxacillin sulfone showed strong mechanism-based irreversible inactivation against type ib penicillinase and proteus vulgaris cephalosporinase whereas it showed no progressive inactivation against cloxa ... | 1985 | 3871761 |
| mechanisms and clinical relevance of antagonism between beta-lactam antibiotics. | the author discussed the problem of antagonism between combined antibiotics. several examples of antagonistic combinations between cefoxitin plus moxalactam, or carbenicillin were cited in the literature. this phenomenon may occur especially with enterobacter spp., pseudomonas aeruginosa, citrobacter spp. and serratia marcescens: in these species induction of chromosomally mediated beta-lactamase by certain potent inducers such as cefoxitin has been suggested as the main mechanism of antagonism. ... | 1985 | 3872724 |
| a perspective on the present contribution of beta-lactamases to bacterial resistance with particular reference to induction of beta-lactamase and its clinical significance. | resistance of bacteria to beta-lactam antibiotics has become a serious problem in the past several decades. virtually all staphylococcus aureus, many haemophilus influenzae, branhamella catarrhalis, neisseria gonorrhoeae, many enterobacteriaceae, many pseudomonas aeruginosa and bacteroides species possess beta-lactamases which hydrolyze to varying degree penems, penams, carbapenems, cephems, cephamycins and monobactams. the most common plasmid-mediated beta-lactamase is the so-called tem beta-la ... | 1985 | 3872725 |
| evidence for nonspecific induction of beta-lactamase in overproducing variants of enterobacter cloacae and citrobacter freundii. | induction of chromosomally mediated beta-lactamases was studied in clinical isolates of enterobacter cloacae and citrobacter freundii. whereas isolates resistant to ampicillin and cefoxitin exhibited an inducible enzyme, those sensitive to both agents did not. cefoxitin and above all imipenem proved the most efficacious enzyme inducers. variants among these inducible isolates which produced large amounts of beta-lactamase could be selected in the presence of cefamandole. in each of these selecte ... | 1985 | 3872794 |
| in vitro and in vivo activities of dn-9550, a new broad-spectrum cephalosporin. | dn-9550 [(6r, 7r)-7-[(z)-2-(2-aminothiazol-4-yl)-2-(1h-imidazol-4-yl) methoxyiminoacetamido]-3-[(1-pyridinio)methyl]-8-oxo-5-thia -1-azabicyclo methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride] is a new semisynthetic cephalosporin with a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria. the activity of dn-9550 against most species of the family enterobacteriaceae was roughly comparable to that of ceftazidime, slightly lower th ... | 1985 | 3873898 |
| covalent binding of moxalactam to cephalosporinase of citrobacter freundii. | the inhibition of citrobacter freundii cephalosporinase activity by moxalactam is shown to be due to the formation of a transiently stable covalent complex, probably acyl enzyme. the covalent complex formed was identified by coelution of [14c] moxalactam with the enzyme by using sephadex g-25 gel filtration in the presence of 5.7 m guanidine hydrochloride and by analytical isoelectric focusing. both the side-chain carboxyl group and the 7 alpha-methoxy group of moxalactam were necessary to stabi ... | 1985 | 3874595 |
| the interaction of beta-lactam compounds with chromosomally mediated enzymes: relations to the molecular structure. | the interaction of 25 beta-lactam compounds with both chromosomally mediated beta-lactamases from enterobacter cloacae and citrobacter freundii was studied by enzyme kinetics. all the penams, cephems, and the penem sch 29482 revealed 'competitive inhibition' of both enzymes. the penem required a preincubation period of approximately 5 min before reaching a state of equilibrium between the active and the inactive enzyme. except for the recently developed compound hr 810, newer cephalosporins gene ... | 1985 | 3875455 |
| gram-negative bacilli resistant to third-generation cephalosporins: beta-lactamase characterization and susceptibility to sch 34343. | we studied 192 recent clinical isolates, comprising six species of gram-negative bacilli resistant either to cefotaxime or latamoxef (moxalactam), from several hospitals. all isolates were resistant to several other third-generation cephalosporins or a monobactam. two to five types of chromosomal beta-lactamases, as defined by isoelectric focusing, were readily identified in each species. isolates of citrobacter, enterobacter and serratia produced higher levels of chromosomal beta-lactamase than ... | 1985 | 3875602 |
| in-vitro activity and beta-lactamase stability and inhibitory properties of a new penem antibiotic, sch 34343. | sch 34343 is a new penem antibiotic. its in-vitro activity was determined against gram-positive and -negative aerobic and anaerobic isolates. sch 34343 inhibited 90% of strains of escherichia coli, klebsiella pneumoniae, proteus mirabilis, salmonella spp, citrobacter spp. and shigella spp. at less than 1 mg/1. ninety per cent of strains of enterobacter, morganella and providencia spp. were inhibited by less than 4 mg/1. sch 34343 did not inhibit pseudomonas spp., and it had slightly less activit ... | 1985 | 3875603 |
| population analysis of susceptibility to cefotaxime and desacetyl-cefotaxime in staphylococcus and enterobacteriaceae. | population analyses of susceptibility to cefotaxime (ctx) and desacetyl-cefotaxime (dctx) of strains of staphylococcus and some genera of enterobacteriaceae were carried out. dctx, which is the main metabolite of ctx, has antimicrobial activity. the penicillinase-producing strains of s. aureus and s. epidermidis were homogeneous as regards susceptibility to both agents. ctx was about 4-8 times more active than dctx. the methicillin-resistant strains contained a sub-population of resistant bacter ... | 1985 | 3875967 |
| multiple antibiotic resistance plasmids in enterobacteriaceae isolated from diarrhoeal specimens of hospitalized children in indonesia. | we studied the plasmid and antibiotic resistance characteristics of 35 strains of enterobacteriaceae recovered from faecal specimens of children with diarrhoea in central general hospital, bandung, indonesia. twenty three escherichia coli, three providencia, three proteus, three klebsiella, two enterobacter and one citrobacter were examined. all strains were multiply resistant, many carrying six to nine antibiotic resistances. most of these resistances were transferable to a laboratory e. coli s ... | 1985 | 3876328 |
| the activity and beta-lactamase stability of cefotetan compared to other beta-lactam antibiotics. | the in vitro activity of cefotetan was assessed against beta-lactamase producing clinical isolates. the majority of enterobacteriaceae were inhibited by less than or equal to 8 micrograms/ml with 50% of isolates inhibited by less than or equal to 1 microgram/ml. cefotetan inhibited organisms resistant to cefazolin, cefonicid and cefoperazone, but not isolates of enterobacter, citrobacter or serratia resistant to ceftizoxime. cefotetan inhibited beta-lactamase producing haemophilus influenzae and ... | 1985 | 3876887 |
| the activity of cefbuperazone, a 7 alpha-methoxy 7 beta acyl ureido cephalosporin. | the activity of cefbuperazone, a 7 alpha-methoxy ureido cephalosporin, was determined against 726 clinical isolates. ninety percent of escherichia coli, klebsiella pneumoniae, klebsiella oxytoca, citrobacter diversus, proteus mirabilis, enterobacter aerogenes, proteus vulgaris, morganella morganii, salmonella, and shigella species were inhibited by less than or equal to 6.3 micrograms/ml. cefbuperazone was more active than cefamandole, cefoxitin and piperacillin against these species. concentrat ... | 1985 | 3879464 |
| biochemical identification of new species and biogroups of enterobacteriaceae isolated from clinical specimens. | in 1972 there were only 11 genera and 26 species in the family enterobacteriaceae. today there are 22 genera, 69 species, and 29 biogroups or enteric groups. this paper is a review of all of the new organisms. it has a series of differential charts to assist in identification and a large chart with the reactions of 98 different organisms for 47 tests often used in identification. a simplified version of this chart gives the most common species and tests most often used for identification. the so ... | 1985 | 3881471 |
| aztreonam in the treatment of serious orthopedic infections. | aztreozam was evaluated in the treatment of a variety of orthopedic infections. included were 17 patients with osteomyelitis, three with purulent arthropathy with prostheses, and 16 with superficial infections secondary to trauma or surgical procedure. pathogens were gram-negative bacilli sensitive to aztreonam. concomitant antibiotics were administered for gram-positive cocci that were present initially or by superinfection. infecting organisms included pseudomonas aeruginosa (minimal inhibitor ... | 1985 | 3881949 |
| application of in-vitro models: development of resistance. | the development of chromosomal beta-lactam resistance of escherichia coli, enterobacter cloacae and citrobacter freundii was observed by following the bacterial kill-kinetics in an in-vitro model simulating human serum antibiotic concentrations. from sensitive escherichia coli cells mutants arose resistant to aminopenicillins, and to first and second generation cephalosporins, whereas with the ent. cloacae and citro. freundii mutants were also resistant to cefotaxime. resistant mutants from all ... | 1985 | 3884569 |
| pathogenesis of escherichia coli cystitis and pyelonephritis: apparent lack of significance of bacterial motility and chemotaxis towards human urine. | all 45 microscopically motile urinary isolates tested here (37 escherichia coli, two enterobacter cloacae, two citrobacter freundii, three proteus mirabilis and one proteus morganii) were strongly attracted to fresh human urine in a capillary chemotaxis assay. this observation suggested that urine taxis of gram-negative bacteria promotes their invasion of the human lower urinary tract and their ascension to the kidney(s). however, the incidence of motile isolates and their activity in urine taxi ... | 1985 | 3886554 |
| an outbreak of antibiotic-resistant salmonella enteritidis in liberia, west africa. | between october 1980 and august 1982, 100 patients in the pediatric population at curran lutheran hospital, zorzor, liberia were identified as having multiple drug-resistant salmonella enteritidis serotype enteritidis. the illness usually presented as an enteric fever but also as meningitis, gastroenteritis, empyema, subcutaneous abscesses, chronic otitis media, or a combination of these conditions. predisposing factors were young age and debilitation from malnutrition or measles. the mortality ... | 1985 | 3886805 |
| inhibitory activity of cefpiramide on beta-lactamase. | the beta-lactamase stability and inhibitory activity of cefpiramide were investigated. cefpiramide was found to be stable to hydrolysis and inhibited beta-lactamase produced by citrobacter freundii, enterobacter cloacae, morganella morganii, and escherichia coli. kinetic studies showed that cefpiramide is a competitive inhibitor of cephaloridine hydrolysis by e. cloacae beta-lactamase. | 1985 | 3888544 |
| in vitro studies on the antibacterial activities of ym-13115, a new broad-spectrum cephalosporin. | the in vitro antibacterial activities of ym-13115, a new parenteral cephalosporin, were compared with those of ceftazidime, cefoperazone, and cefsulodin. the compound was highly active against the common members of the enterobacteriaceae and 2 to 256 times more active than cefoperazone. ym-13115 was as active as ceftazidime against citrobacter freundii, proteus vulgaris, and morganella morganii and two to four times more active than ceftazidime against escherichia coli, klebsiella pneumoniae, en ... | 1985 | 3890729 |
| in vitro antibacterial activity of ceftizoxime against gram-negative strains. | the in vitro activity of ceftizoxime against 200 clinical isolates of enterobacteria and pseudomonas, was compared with those of other beta-lactam antibiotics such as: cefotaxime, cefoperazone, cefuroxime, and the aminoglycosides gentamicin and amikacin. ceftizoxime inhibited escherichia coli and klebsiella pneumoniae with doses from two to four fold lower than cefotaxime. ceftizoxime and cefotaxime were more active than cefuroxime and cefoperazone against enterobacter spp., and proteus morganii ... | 1985 | 3891115 |
| aztreonam in the therapy of nosocomial infections in patients with impaired host defenses. | a clinical trial was carried out to evaluate the effectiveness of treatment with aztreonam in hospital-acquired infections. twenty patients (13 men and 7 women) with impaired host defenses and nosocomial infections were treated with aztreonam at a dosage ranging 4 and 6 g/day i.v. at 8 or 12-hour intervals. average length of therapy was 10.35 +/- 4.61 days. the isolated organisms were as follows: escherichia coli (5), pseudomonas aeruginosa (5), klebsiella pneumoniae (3), enterobacter cloacae (1 ... | 1985 | 3891117 |
| rapid and automated detection of salmonella by electrical measurements. | a rapid method for determining the presence of salmonella in food is described. it consists of pre-enrichment in buffered peptone water modified by the addition of dulcitol and trimethylamine oxide, followed by selective enrichment in a selenite-cystine broth with similar modifications. changes in the conductance of the selective enrichment broth are monitored continuously using a suitable impediometric instrument. most of the salmonella spp. tested gave a fast (approximately 100 micros/h) and l ... | 1985 | 3891846 |
| new beta-lactam antibiotics in granulocytopenic patients. new options and new questions. | infectious complications are a frequent cause of morbidity and, at many centers, the major cause of death in patients with cancer. the increased risk and severity of infectious sequelae result from profound alterations in normal host defenses that occur secondary to the underlying malignancy and the treatment thereof. during the last decade, early empiric antibiotic therapy has become standard practice in the initial management of febrile granulocytopenic patients and has contributed significant ... | 1985 | 3895922 |
| therapeutic experience with temocillin in peritonitis. | the therapeutic efficacy of the new beta-lactam antibiotic, temocillin, was studied in 30 critically ill patients with peritonitis, abscesses, bronchopneumonia, and serious soft tissue infections. patients were treated with temocillin ig intravenously twice daily. the isolated pathogens comprised mainly escherichia coli and proteus, but enterococci, pseudomonas species, klebsiella pneumoniae, citrobacter species, bacteroides species, streptococci and peptococci were also implicated. temocillin w ... | 1985 | 3896740 |
| sch 34343 activity against streptococci and beta-lactam-resistant enterobacteriaceae. | the in-vitro activity of sch 34343 was compared with that of cefotaxime, ceftazidime, latamoxef (moxalactam), aztreonam and ampicillin. against pneumococci, sch 34343 was as active as ampicillin, whereas against the other streptococci it was less active than ampicillin but significantly better than the other antibiotics against enterococci. with clinical isolates of enterobacteriaceae resistant to cefotaxime, sch 34343 had mics generally less than 2 mg/l. after introduction of plasmid-mediated b ... | 1985 | 3897168 |
| sch 34343: in-vitro antibacterial activity and susceptibility to beta-lactamases. | the in-vitro activity of the penem sch 34343 was assessed in comparison with third-generation cephalosporins, aztreonam and imipenem. sch 34343 was active, with mics generally 2 mg/1 or less, against a broad spectrum of organisms amongst which were staphylococci (including methicillin-resistant strains), streptococci (though enterococci were less susceptible with sch 34343 mics mostly 4-8 mg/1), anaerobes (including the bacteroides fragilis group), haemophilus influenzae and neisseria gonorrhoea ... | 1985 | 3897169 |
| bacteremias due to citrobacter diversus and citrobacter freundii. incidence, risk factors, and clinical outcome. | from 1974 to 1982, 38 patients developed citrobacter bacteremia at two adult community-teaching hospitals in the detroit medical center (incidence, 1.2 cases per 10,000 discharges). citrobacter accounted for 0.7% of all bacteremias during the study period. of 31 cases reviewed, citrobacter bacteremia frequently developed in elderly patients (65%) and was hospital acquired (77%). initial sites of infection included the urinary tract (39%), gastrointestinal tract (27%), wound (10%), and unknown (1 ... | 1985 | 3899035 |
| trat gene sequences, serum resistance and pathogenicity-related factors in clinical isolates of escherichia coli and other gram-negative bacteria. | the r6-5 plasmid-specified outer membrane protein, trat protein, has previously been shown to mediate resistance to bacterial killing by serum. colony hybridization with a 700 bp dna fragment carrying most of the trat gene was used to examine the prevalence of trat in gram-negative bacteria, particularly strains of escherichia coli, isolated from clinical specimens. trat was found in isolates of e. coli, salmonella, shigella and klebsiella, but not in pseudomonas, aeromonas or plesiomonas, nor i ... | 1985 | 3900279 |
| changes in the incidence and spectrum of neonatal septicemia during a fifteen-year period. | over a period of 15 years the incidence of neonatal septicemia seen at st göran's children's hospital has increased both per 1000 births and per 100 admitted neonates. the spectrum of causative organisms has changed towards more gram-positive organisms and fewer gram-negative organisms. in the initial antibiotic treatment an aminoglycoside and ampicillin derivate will still be needed to give full coverage. | 1985 | 3901662 |
| [carbenicillin resistance of gram-negative bacteria: incidence, biochemical and genetic determinism]. | of nine hundred ampicillin resistant (amp-r) enterobacteria strains, isolated in hospital between july and december 1981, 73,7% are also carbenicillin-resistant (carb-r). this particular double resistance varies depending upon the species considered: indole positive proteus (23%), enterobacter cloacae (64%), citrobacter freundii (67%), acinetobacter calcoaceticus (73%), proteus mirabilis (75%), serratia marcescens (90%), escherichia coli (91%), providencia stuartii (96%) and klebsiella pneumonia ... | 1985 | 3903620 |
| ceftriaxone: a beta-lactamase-stable, broad-spectrum cephalosporin with an extended half-life. | ceftriaxone is an aminothiazolyl-oxyimino cephalosporin. it possesses the typical in vitro activity of a third-generation cephalosporin with excellent activity against many gram-negative aerobic bacilli: escherichia coli; species of proteus, klebsiella, morganella, providencia and citrobacter; and enterobacter agglomerans. ceftriaxone also has outstanding bactericidal action against pneumococci, group b streptococci, meningococci, gonococci and hemophilus influenzae. in healthy volunteers, it ha ... | 1985 | 3906584 |
| contribution of beta-lactamases to bacterial resistance and mechanisms to inhibit beta-lactamases. | resistance of bacteria to beta-lactam antibiotics has become a serious problem in the past several decades. virtually all staphylococcus aureus, and many hemophilus influenzae, branhamella catarrhalis, neisseria gonorrhoeae, enterobacteriaceae, and bacteroides species possess beta-lactamases that hydrolyze penicillins and cephalosporins. the most common plasmid-mediated beta-lactamase is the tem enzyme (richmond-sykes type iiia), which is present in hemophilus, neisseria, and enterobacteriaceae. ... | 1985 | 3907341 |
| [biochemical properties of enterobacteria on polystyrene plates]. | the authors studied 84 strains of enterobacteria. the reliability of the results of the biochemical testing obtained by the micromethod with the use of polystyrene plates was examined comparatively to the data obtained by the classical method and api microsystems manufactured in france. of the 84 strains of enterobacteria, 36 belonged to proteus, 24 to enterobacter, 8 to klebsiella, 5 to citrobacter, and 11 to e. coli. of the strains tested, 50 were isolated from the intestine of children and ad ... | 1985 | 3909634 |
| cefamandole resistance transfer in bacterial strains from two newborn units. | transfer of cefamandole resistance was demonstrated from strains of citrobacter freundii as well as from individual strains of enterobacter cloacae, acinetobacter anitratus and klebsiella pneumoniae isolated from patients in two newborn units. in citrobacter freundii, cefamandole resistance was transferred always with cephalotin resistance as well as with a tem-like beta lactamase (conferring resistance to ampicillin, carbenicillin and azlocillin). citrobacter freundii strains from hospital i we ... | 1985 | 3910723 |
| rapid identification of escherichia coli from routine urine specimens based on macroscopic criteria. | in our laboratory, selected strains of gram-negative rods from urine samples are identified as escherichia coli on the basis of smell and morphology on lactose agar. to investigate the accuracy of this routine practice, 211 consecutive strains were tested in the urea-indole tube of the three-tube method (3-tm), in the pgua test detecting beta-glucuronidase activity and in the simmons' citrate test, to select the strains that were non-e. coli. additional 1022 strains were tested by the indole and ... | 1985 | 3914821 |
| studies on specificity of protection induced by immunization with outer membrane proteins of shigella. | immunization of c3h/hej mice with outer membrane proteins (omp) and with peptidoglycan associated proteins (pgp) isolated from shigella flexneri 3a and from shigella sonnei phase i protected the animals against lethal dose of homologous and heterologous bacteria and against various serotypes of shigella flexneri. neither of the protein preparations protected the animals against challenge with escherichia, klebsiella, citrobacter, salmonella, serratia, proteus and pseudomonas. omp preparations ho ... | 1985 | 3914866 |
| [enzymatic synthesis of 3,4-dihydroxyphenyl-l-alanine by free and immobilized citrobacter freundii cells]. | the citrobacter freundii 62 cells immobilized in paag and possessing the tyrosine-phenol-lyase (tpl) activity catalyse the synthesis of 3,4-dihydroxyphenyl-l-alanine (dopa) from pyrocatechol and ammonium pyruvate. the synthesis of dopa was studied using both free and immobilized bacterial cells. when the concentration of pyrocatechol is over 0.1 m the tpl activity of the cells is inhibited. the concentration of pyrocatechol can be increased up to 0.3 m by using an equimolar mixture of pyrocatech ... | 1985 | 3921951 |
| the in vitro activity and beta-lactamase stability of cefpirome (hr 810), a pyridine cephalosporin agent active against staphylococci, enterobacteriaceae and pseudomonas aeruginosa. | the in vitro activity of cefpirome, a new cyclopyridinium cephalosporin, was evaluated against 947 aerobic and anaerobic bacteria. cefpirome inhibited 90% of escherichia coli, klebsiella spp., citrobacter diversus, morganella morganii, proteus vulgaris, proteus mirabilis, aeromonas spp., salmonella spp., shigella spp. and haemophilus and neisseria species at less than or equal to 0.4 mg/l. it had activity comparable to that of cefotaxime, ceftizoxime, ceftazidime, aztreonam, and moxalactam again ... | 1985 | 3928497 |
| [activity of the amoxicillin-clavulanic acid (augmentin) combination on strains of hospital isolates]. | all strains of staphylococcus aureus and gram negative bacilli (enterobacteriaceae, pseudomonas aeruginosa, acinetobacter) isolated from 01.01 to 03.31.83 were studied using agar diffusion with augmentin-impregnated discs (amoxicillin 20 micrograms + clavulanic acid 10 micrograms). augmentin is active against penicillinase-producing staphylococci susceptible to methicillin, whereas methicillin-resistant strains are also resistant to augmentin. according to the susceptibility of strains to amoxic ... | 1985 | 3929215 |
| [laboratory and clinical studies on cefminox]. | laboratory and clinical studies were performed on cefminox (cmnx, mt-141), a new cephamycin antibiotic, and results were as follows. antimicrobial activities. mics of cmnx against various clinical isolates were determined with the inoculum size of 10(6) cells/ml. percentages of strains susceptible to 12.5 micrograms/ml or less were 4% for s. aureus, 0% for e. faecalis, 100% for e. coli, 81% for k. pneumoniae, 3% for enterobacter sp., 18% for s. marcescens, 90% for p. mirabilis, 88% for indole-po ... | 1985 | 3930782 |
| [cefminox concentration in tissues and clinical efficacy of cefminox in acute peritonitis]. | cefminox sodium (cmnx, mt-141), a new semisynthetic cephamycin, having marked resistance to beta-lactamase, and a broad spectrum of antibacterial activity against various bacterial species, including haemophilus influenzae, serratia marcescens and citrobacter freundii, cmnx has higher activity in vivo than in vitro. for therapeutic purpose, cmnx was given in a daily dose of 0.5 g (0.5 g x 1) to 2 g (1 x 2) by intravenous drip infusion for 4 to 8 days to 24 cases with acute peritonitis (17 cases ... | 1985 | 3930784 |
| [distribution and changes in the susceptibility of bacteria isolated from clinical samples. iii]. | this report presents data concerning in vitro activity of antimicrobial agents against citrobacter freundii, enterobacter spp., serratia marcescens and proteus vulgaris isolated from patients with complicated urinary tract infections and against pseudomonas aeruginosa isolated from surgical wounds with postoperative infection and exudate from superficial abscesses. there was a marked increase of resistant strains of c. freundii, enterobacter spp. and s. marcescens to penicillins, ceps or gm. the ... | 1985 | 3930806 |
| [synthesis of tyrosine and 3,4-dihydroxyphenylalanine by citrobacter freundii bacteria from lactic acid]. | a possibility of using lactic acid as a precursor for the synthesis of l-tyrosine and l-3,4-dihydroxyphenylalanine (dopa) by citrobacter freundii 62 and 63 was established. the synthesis of tyrosine from lactic acid occurs at a phenol concentration of less than 0.6%. the conditions were found which enable c. freundii 62 and 63 to synthesize from lactic acid tyrosine and dopa with the yield of 35-38 g/l and 32-33 g/l, respectively. | 1985 | 3931068 |
| [characteristics of the composition of the causative agents of different forms of suppurative inflammatory diseases and their antibiotic sensitivity]. | antibiotic sensitivity of 466 clinical strains of gram-positive and gram-negative microorganisms isolated from patients with different forms of pyoinflammatory diseases was studied. most of the staphylococcal isolates were resistant to benzylpenicillin (74.3 per cent). the number of the isolates resistant to erythromycin amounted to 59.6 per cent. the respective figures for methicillin and dicloxacillin were 17.9 and 10.8 per cent. staphylococci resistant to new aminoglycosides, fusidin and rifa ... | 1985 | 3933419 |
| infection control during parenteral nutrition therapy. | parenteral nutrition therapy can achieve an anabolic state in patients who are unable to maintain normal nitrogen balance; however, it may be associated with infectious complications. infections may be related to contamination of the cannula and the cannula wound, of the infusate, or of other parts of the parenteral nutrition system. a variety of microorganisms has been associated with these infections. the exact mechanisms that initiate cannula-related infection are poorly understood. susceptib ... | 1985 | 3934408 |
| [comparative studies of antimicrobial agents against causative organisms isolated from urinary tract infections (1983). iii. secular changes in susceptibility]. | the in vitro antimicrobial activities of antibiotics against causative pathogens isolated from patients with urinary tract infections (uti) in the 8 institutions in japan during the period from 1980 to 1983 were compared. a number of new beta-lactam antibiotics with broad spectrum of activity have become available for clinical use in recent years. some of them, in particular so-called third generation cephems, are reported to be responsible for developing microbial-cross resistance to multiple b ... | 1985 | 3935824 |
| [effect of ceftazidime on enterobacteria and pseudomonas producers of beta-lactamases]. | the activity of cephalotin, cefoxitin, cefamandole, cefoperazone, cefotaxime, latamoxef, thienamycin, azthreonam, cefsulodine and ceftazidime against beta-lactamase producing strains of enterobacteriaceae and pseudomonas was compared by determination of 99% inhibitory concentrations. the isogenic strains studied differed by a single genetic event: mutation, gene amplification, acquisition of a high or low copy-number plasmid or of a transposon and were representative of the major known mechanism ... | 1985 | 3936006 |
| toxic exoproducts of citrobacter freundii. | a strain of citrobacter freundii isolated from the feces of a patient with diarrhoea was examined for growth kinetics and toxic exoproduct formation using the complete (bhi) and synthetic culture media. it was found that the test organism in synthetic medium grew distinctly slower than in bhi. fractionations on sephadex g-100 column yielded 3 fractions from the complete medium culture filtrate and 2 fractions from the culture filtrate obtained from synthetic medium. the first culture filtrate fr ... | 1985 | 3936878 |
| bacteriology and ultrastructure of the bladder in patients with urinary tract infections. | tissue obtained by biopsy of the bladder from 33 patients with various urinary tract symptoms was studied by conventional bacteriological techniques and by scanning electron microscopy (sem). all the patients had recurrent urinary tract symptoms which had not completely responded to antibiotic therapy. eleven of the patients had greater than or equal to 10(8) colony-forming units (cfu) of bacteria/1 urine; six had between 10(6) and 10(7) cfu/1, and 16 were abacteruric. bacteria were isolated, ho ... | 1985 | 3936879 |
| [in vitro effect of ceftriaxone on hospital bacteria. line of regression and critical values]. | antimicrobial activity of ceftriaxone, a new third generation cephalosporin, against hospital isolates was investigated. 312 strains belonging to the most commonly recovered species were studied using the following methods: agar diffusion (disk antibiotic testing), agar dilution (determination of mic) and dilution in a liquid medium with subculture to agar plates (determination of mbc). except for a few citrobacter strains and rare serratia strains, all enterobacteriaceae tested proved highly su ... | 1985 | 3937122 |
| [hr 810 (cefpirome). experimental evaluation of the in vitro and in vivo antibiotic activity of a new amino-2-thiazole methoxy- imino cephalosporin]. | hr 810 or cefpirome is a new amino thiazole cephalosporin whose specific characteristic is a cyclopentenopyridinium group in position 3 of the cephem nucleus. this structure is responsible for a broad spectrum of activity, covering enterobacteriaceae, including cephalosporinase-producing enterobacter spp. and citrobacter spp., staphylococcus aureus, pseudomonas aeruginosa and group d streptococci. | 1985 | 3937124 |
| conservation of dna sequences for plasmid-mediated citrate utilization within the enterobacteria. | southern blot dna-dna hybridization experiments with a cloned cit+ dna fragment as a probe showed that the plasmid-mediated cit+ determinants from four cit plasmids (r726, poh3001, poh3035, and poh30221) were all homologous. sequences homologous to the plasmid-borne cit+ gene were also found in total bacterial dna isolated from salmonella paratyphi b, salmonella enteritidis, salmonella typhimurium lt-2, citrobacter freundii, atcc 8090, citrobacter amalonaticus atcc 25405, klebsiella pneumoniae i ... | 1986 | 3941048 |
| opportunistic infections in hysterectomy-derived, barrier-maintained guinea pigs. | guineapigs were rederived by hysterectomy and associated with a colonization-resistant enteric microflora (crf) of mouse origin to establish a strict barrier-maintained breeding colony. infections were suspected in 55 of 209 animals autopsied. from 65 of 67 tissue samples selected for bacteriological examination 167 isolates, belonging to 16 usually non-pathogenic bacterial species or groups, were isolated mostly from cases of mastitis, typhlitis, enteritis, otitis media and pneumonia. faecal st ... | 1986 | 3951194 |
| mercury resistant bacteria isolated from sediment. | | 1986 | 3955253 |
| selective and differential medium for the primary isolation of members of the proteeae. | a new differential and selective medium for the isolation of members of the proteeae, pim (proteeae isolation medium) agar, was developed and evaluated. the medium relies on the ability of all members of the proteeae (with the exception of a very few morganella morganii strains) to produce a dark brown pigment in medium containing dl-tryptophan. an additional differential property, tyrosine degradation, was also demonstrated by the medium. members of the proteeae appeared as dark brown colonies ... | 1986 | 3958148 |
| [isolation and properties of citrobacter bacteriophages]. | four phages differing in their antigenic properties, thermosensitivity and spectrum of action have been obtained from citrobacter lysogenic cultures. to prepare the suspension of citrobacter phages, phagolysates may be treated with chloroform 1:10 for 30 minutes. the isolated phages have proved to be highly specific. the possibility of distinguishing citrobacter cultures by means of the phages under study has been shown. | 1986 | 3962533 |
| studies on microorganisms secured from different organs of slaughtered sheep with special reference to the microbial load in certain muscles. | a total of 312 samples collected from different organs and muscles of dead, disabled, diseased, dying, and normal carcasses of sheep were examined bacteriologically to determine the different species of microorganisms as to their public health significance. in addition, the aerobic plate count (apc) and most probable number (mpn) coliform/g were determined of musculus biceps brachii, musculus quadriceps femoris, and musculus longissimus dorsi. the mean bacterial load was higher in summer than in ... | 1986 | 3964203 |