Publications

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in vitro activity of pexiganan and 10 comparator antimicrobials against 234 isolates including 93 pasteurella spp. and 50 anaerobic bacteria recovered from animal bite wounds.animal bite wounds affect more than 5 million americans resulting in 300,000 emergency department visits, 10,000 hospitalizations and untold number of physician office visits annually. various forms of topical therapy are empirically self-employed by many patients prior to seeking medical attention. pexiganan, a 22-amino acid synthetic cationic analogue of peptide magainin ii, acts by selectively damaging bacterial cell membranes. we determined the mics for pexiganan and other antimicrobial agen ...201728373186
impact of antibiotic resistance in the management of ocular infections: the role of current and future antibiotics.this article reviews the effects of the increase in bacterial resistance on the treatment of ocular infections.200919789660
role of cognitive parameters in dengue hemorrhagic fever and dengue shock syndrome.dengue is becoming recognized as one of the most important vector-borne human diseases. it is predominant in tropical and subtropical zones but its geographical distribution is progressively expanding, making it an escalating global health problem of today. dengue presents with spectrum of clinical manifestations, ranging from asymptomatic, undifferentiated mild fever, dengue fever (df), to dengue hemorrhagic fever (dhf) with or without shock (dss), a life-threatening illness characterized by pl ...201324305068
evaluation of different wastewater treatment processes and development of a modified attached growth bioreactor as a decentralized approach for small communities.this study was undertaken to evaluate the potential future use of three biological processes in order to designate the most desired solution for on-site treatment of wastewater from residential complexes, that is, conventional activated sludge process (casp), moving-bed biofilm reactor (mbbr), and packed-bed biofilm reactor (pbbr). hydraulic retention time (hrt) of 6, 3, and 2 h can be achieved in casp, mbbr, and pbbr, respectively. the pbbr dealt with a particular arrangement to prevent the res ...201324327802
types and drug susceptibility patterns of bacterial isolates from eye discharge samples at gondar university hospital, northwest ethiopia.the type and pattern of organisms that cause ocular infection changes over time. moreover, the causative organisms have developed increased drug resistance. therefore, the aim of this study was to determine the prevalent bacterial agents of eye discharge and their drug susceptibility patterns to commonly used antimicrobial agents.201424885599
nasopharyngeal microbiota in healthy children and pneumonia patients.our study is the first to compare the nasopharyngeal microbiota of pediatric pneumonia patients and control children by 454 pyrosequencing. a distinct microbiota was associated with different pneumonia etiologies. viral pneumonia was associated with a high abundance of the operational taxonomic unit (otu) corresponding to moraxella lacunata. patients with nonviral pneumonia showed high abundances of otus of three typical bacterial pathogens, streptococcus pneumoniae complex, haemophilus influenz ...201424599973
draft genome sequence of moraxella bovoculi strain 237t (atcc baa-1259t) isolated from a calf with infectious bovine keratoconjunctivitis.moraxella bovoculi is a recently identified species, recovered from the bovine eye, which is under investigation as an etiological agent of infectious bovine keratoconjunctivitis. a draft genome sequence of the moraxella bovoculi type strain 237(t) has been determined to identify features that may be important during host colonization.201424970830
conjunctivitis: diagnosis and management. 199917491982
[undulant fever and autoimmune hemolytic anemia in a 20-year-old exchange student from jordan - the human brucellosis as an important differential diagnosis in migrants].a 20-year-old jordanian exchange student presents with recurrent fever, night sweats, cough, and swelling and redness around the ankle. physical examination further reveals bilateral ankle arthritis and painful cervical lymphadenopathy.201526625239
conservative approach in the management of severe acute pancreatitis: eight-year experience in a single institution.recognition of severe acute pancreatitis (sap), intensive care, shifting away from early surgical treatment, and monitoring of the intra-abdominal pressure (iap) is important in the management of sap. the aim of our study was retrospective evaluation and critical assessment of the experience with sap management protocol involving new strategy in the university hospital.200818982151
transaminases for the synthesis of enantiopure beta-amino acids.optically pure β-amino acids constitute interesting building blocks for peptidomimetics and a great variety of pharmaceutically important compounds. their efficient synthesis still poses a major challenge. transaminases (also known as aminotransferases) possess a great potential for the synthesis of optically pure β-amino acids. these pyridoxal 5'-dependent enzymes catalyze the transfer of an amino group from a donor substrate to an acceptor, thus enabling the synthesis of a wide variety of chir ...201222293122
moraxella lacunata infection associated with septicemia, endocarditis, and bilateral septic arthritis in a patient undergoing hemodialysis: a case report and review of the literature.we report the first case of both endocarditis and bilateral septic arthritis in a patient caused by moraxella lacunata and successful management of the infection with antimicrobial therapy. the route of entry leading to bacteremia may have been the oral cavity given the poor oral hygiene of the patient as evidenced by bleeding gums. we hypothesize that the bacteremia led to septic arthritis and mitral valve infective endocarditis. in this case report, we also review the literature on m. lacunata ...201424462428
[keratitis due to moraxella lacunata: a case report]. 201323817656
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