Publications

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sars-cov-2 in fruit bats, ferrets, pigs, and chickens: an experimental transmission study.in december, 2019, a novel zoonotic severe acute respiratory syndrome-related coronavirus emerged in china. the novel severe acute respiratory syndrome coronavirus 2 (sars-cov-2) became pandemic within weeks and the number of human infections and severe cases is increasing. we aimed to investigate the susceptibilty of potential animal hosts and the risk of anthropozoonotic spill-over infections.202032838346
predicting susceptibility to sars-cov-2 infection based on structural differences in ace2 across species.severe acute respiratory syndrome coronavirus 2 (sars-cov-2) is the cause of the global pandemic of coronavirus disease-2019 (covid-19). sars-cov-2 is a zoonotic disease, but little is known about variations in species susceptibility that could identify potential reservoir species, animal models, and the risk to pets, wildlife, and livestock. certain species, such as domestic cats and tigers, are susceptible to sars-cov-2 infection, while other species such as mice and chickens are not. most ani ...202033015868
susceptibility of ferrets, cats, dogs, and other domesticated animals to sars-coronavirus 2.severe acute respiratory syndrome-coronavirus 2 (sars-cov-2) causes the infectious disease covid-19 (coronavirus disease 2019), which was first reported in wuhan, china, in december 2019. despite extensive efforts to control the disease, covid-19 has now spread to more than 100 countries and caused a global pandemic. sars-cov-2 is thought to have originated in bats; however, the intermediate animal sources of the virus are unknown. in this study, we investigated the susceptibility of ferrets and ...202032269068
generation of chicken igy against sars-cov-2 spike protein and epitope mapping.this new decade has started with a global pandemic of covid-19 caused by severe acute respiratory syndrome coronavirus 2 (sars-cov-2), precipitating a worldwide health crisis and economic downturn. scientists and clinicians have been racing against time to find therapies for covid-19. repurposing approved drugs, developing vaccines and employing passive immunization are three major therapeutic approaches to fighting covid-19. chicken immunoglobulin y (igy) has the potential to be used as neutral ...202033134398
non-respiratory presentations of covid-19, a clinical review.severe acute respiratory syndrome coronavirus 2 (sars-cov-2 or covid-19) is a highly infectious viral syndrome currently threatening millions of people worldwide. it is widely recognized as a disease of the pulmonary system, presenting with fever, cough, and shortness of breath. however, a number of extrapulmonary manifestations have been described in the literature.202033039218
a scalable topical vectored vaccine candidate against sars-cov-2.the severe acute respiratory syndrome-coronavirus 2 (sars-cov-2) caused an ongoing unprecedented global public health crises of coronavirus disease in 2019 (covid-19). the precipitously increased death rates, its impact on livelihood and trembling economies warrant the urgent development of a sars-cov-2 vaccine which would be safe, efficacious and scalable. owing to unavailability of the vaccine, we propose a de novo synthesized avian orthoavulavirus 1 (aoav-1)-based topical respiratory vaccine ...202032846910
severe acute respiratory syndrome coronavirus-2 (sars-cov-2): an update.coronaviruses (covs) belong to the family of coronaviridae, the order nidovirales, and the genus coronavirus. they are the largest group of viruses causing respiratory and gastrointestinal infections. morphologically, covs are enveloped viruses containing a non-segmented positive-sense, single-stranded ribonucleic acid (rna) viruses. covs are categorized into four important genera that include alphacoronavirus, betacoronavirus, gammacoronavirus, and deltacoronavirus. a novel member of human cov ...202032337143
can immunization of hens provide oral-based therapeutics against covid-19?in the current worldwide pandemic situation caused by the severe acute respiratory syndrome coronavirus 2 (sars-cov-2) and the newest coronavirus disease (covid-19), therapeutics and prophylactics are urgently needed for a large population. some of the prophylaxis strategies are based on the development of antibodies targeting viral proteins. igy antibodies are a type of immunoglobulin present in birds, amphibians, and reptiles. they are usually obtained from egg yolk of hyper-immunized hens and ...202032872186
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