middle east respiratory syndrome (mers) coronavirus seroprevalence in domestic livestock in saudi arabia, 2010 to saudi arabia, including regions of riyadh and al ahsa, pseudoparticle neutralisation (ppnt) and microneutralisation (mnt) tests detected no antibodies to middle east respiratory syndrome coronavirus (mers-cov) in sheep (n= 100), goats (n= 45), cattle (n= 50) and chickens (n= 240). dromedary camels however, had a high prevalence of mers-cov antibodies. bovine coronavirus (bcov) infected sera from cattle had no cross-reactivity in mers-cov ppnt or mnt, while many dromedary camels’ sera reacted ...201324342517
recent advances in aiv biosensors composed of nanobio hybrid material.since the beginning of the 2000s, globalization has accelerated because of the development of transportation systems that allow for human and material exchanges throughout the world. however, this globalization has brought with it the rise of various pathogenic viral agents, such as middle east respiratory syndrome coronavirus (mers-cov), severe acute respiratory syndrome coronavirus (sars-cov), zika virus, and dengue virus. in particular, avian influenza virus (aiv) is highly infectious and cau ...201830544883
anti-s1 mers-cov igy specific antibodies decreases lung inflammation and viral antigen positive cells in the human transgenic mouse model.the middle east respiratory syndrome coronavirus (mers-cov) was identified in 2012 and causes severe and often fatal acute respiratory illness in humans. no approved prophylactic and therapeutic interventions are currently available. in this study, we have developed egg yolk antibodies (immunoglobulin y (igy)) specific for mers-cov spike protein (s1) in order to evaluate their neutralizing efficiency against mers-cov infection. s1-specific immunoglobulins were produced by injecting chickens with ...202033139631
newcastle disease virus-based mers-cov candidate vaccine elicits high-level and lasting neutralizing antibodies in bactrian camels.middle east respiratory syndrome coronavirus (mers-cov), a member of the coronaviridae family, is the causative pathogen for mers that is characterized by high fever, pneumonia, acute respiratory distress syndrome (ards), as well as extrapulmonary manifestations. currently, there are no approved treatment regimens or vaccines for mers. here, we generated recombinant nonvirulent newcastle disease virus (ndv) lasota strain expressing mers-cov s protein (designated as rla-mers-s), and evaluated its ...201732288953
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