Publications

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neutralizing antibodies against flaviviruses, babanki virus, and rift valley fever virus in ugandan bats.introduction:a number of arboviruses have previously been isolated from naturally-infected east african bats, however the role of bats in arbovirus maintenance is poorly understood. the aim of this study was to investigate the exposure history of ugandan bats to a panel of arboviruses.materials and methods:insectivorous and fruit bats were captured from multiple locations throughout uganda during 2009 and 2011-2013. all serum samples were tested for neutralizing antibodies against west nile viru ...201829511459
subgenomic flavivirus rna (sfrna) associated with asian lineage zika virus identified in three species of ugandan bats (family pteropodidae).serological cross-reactivity among flaviviruses makes determining the prior arbovirus exposure of animals challenging in areas where multiple flavivirus strains are circulating. we hypothesized that prior infection with zikv could be confirmed through the presence of subgenomic flavivirus rna (sfrna) of the 3' untranslated region (utr), which persists in tissues due to xrn-1 stalling during rna decay. we amplified zikv sfrna but not ns5 from three experimentally-infected jamaican fruit bats, sup ...202133863991
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