exogenous porcine viruses.porcine organs, cells and tissues provide a viable source of transplants in humans, though there is some concern of public health risk from adaptation of swine infectious agents in humans. limited information is available on the public health risk of many exogenous swine viruses, and reliable and rapid diagnostic tests are available for only a few of these. the ability of several porcine viruses to cause transplacental fetal infection (parvoviruses, circoviruses, and arteriviruses), emergence or ...200312934944
coinfection of pigs with porcine respiratory coronavirus and bordetella bronchiseptica.coinfection with two or more pathogens is a common occurrence in respiratory diseases of most species. the manner in which multiple pathogens interact is not always straightforward, however. bordetella bronchiseptica and porcine respiratory coronavirus (prcv) are respiratory pathogens of pigs whose relatives, b. pertussis and the sars virus, cause respiratory disease in humans. in an initial experiment, the effect of coinfection of prcv and b. bronchiseptica was examined in thirty, 4-week-old pi ...200818022332
prevalence of antibodies to selected viral pathogens in wild boars (sus scrofa) in croatia in 2005-06 and 2009-10.we determined prevalence of antibody to selected viral pathogens important for domestic pigs and livestock in 556 wild boar (sus scrofa) sera collected during 2005-06 and 2009-10 in four counties in croatia. these counties account for an important part of the croatian commercial pig production and have a high density of wild boars. samples were tested for antibodies to porcine parvovirus (ppv), aujeszky's disease virus (adv), porcine circovirus type 2 (pcv2), swine influenza virus, porcine respi ...201222247381
epidemiological survey of enteric viruses in wild boars in the czech republic: first evidence of close relationship between wild boar and human rotavirus a strains.population of wild boar is increasing in the whole europe, the animals migrate close to human habitats which greatly increases the possibility of natural transmission between domestic animals or humans and wild boars. the aim of the study was to estimate in population of free-living wild boar in the czech republic the prevalence of enteric viral pathogens, namely rotavirus groups a and c (rva and rvc), porcine reproductive and respiratory syndrome virus (prrsv), and members of family coronavirid ...201627599927
retrospective serological survey on selected viral pathogens in wild boar populations in germany.the objective of this study was to retrospectively evaluate the occurrence of porcine parvovirus (ppv), aujeszky's disease virus (adv), transmissible gastroenteritis virus (tgev), porcine respiratory coronavirus (prcv), porcine reproductive and respiratory syndrome virus (prrsv) and swine influenza virus (siv) in selected wild boar populations in germany (n  = 1,221). commercial enzyme linked immunosorbent assay and hemagglutination inhibition tests were used for serological monitoring. the sero ...200932214937
comparative pathogenesis of bovine and porcine respiratory coronaviruses in the animal host species and sars-cov-2 in humans.discovery of bats with severe acute respiratory syndrome (sars)-related coronaviruses (covs) raised the specter of potential future outbreaks of zoonotic sars-cov-like disease in humans, which largely went unheeded. nevertheless, the novel sars-cov-2 of bat ancestral origin emerged to infect humans in wuhan, china, in late 2019 and then became a global pandemic. less than 5 months after its emergence, millions of people worldwide have been infected asymptomatically or symptomatically and at leas ...202032522830
anti-tnf-alpha therapy does not ameliorate disease in a model of acute virus-endotoxin mediated respiratory disease in pigs.tumour necrosis factor-alpha (tnf-alpha) has been shown to play a role in many inflammatory conditions. currently anti-tnf-alpha drugs (e.g. etanercept) are used in humans for treatment of autoimmune diseases. in this study we aimed to elucidate the role of tnf-alpha in the development of virus-endotoxin-induced respiratory disease. twenty-two caesarean derived colostrum deprived pigs were used. initially, the availability in the lungs and circulation, and possible clinical and inflammatory effe ...201020466438
altered pathogenesis of porcine respiratory coronavirus in pigs due to immunosuppressive effects of dexamethasone: implications for corticosteroid use in treatment of severe acute respiratory syndrome coronavirus.the pathogenesis and optimal treatments for severe acute respiratory syndrome (sars) are unclear, although corticosteroids were used to reduce lung and systemic inflammation. because the pulmonary pathology of porcine respiratory coronavirus (prcv) in pigs resembles sars, we used prcv as a model to clarify the effects of the corticosteroid dexamethasone (dex) on coronavirus (cov)-induced pneumonia. conventional weaned pigs (n = 130) in one of four groups (prcv/phosphate-buffered saline [pbs] [n ...200717942563
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