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a comprehensive microbiological safety approach for agarose encapsulated porcine islets intended for clinical trials.the use of porcine islets to replace insulin-producing islet β-cells, destroyed during the diabetogenic disease process, presents distinct challenges if this option is to become a therapeutic reality for the treatment of type 1 diabetes. these challenges include a thorough evaluation of the microbiological safety of the islets. in this study, we describe a robust porcine islet-screening program that provides a high level of confidence in the microbiological safety of porcine islets suitable for ...201627862363
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