| replication of mers and sars coronaviruses in bat cells offers insights to their ancestral origins. | previous findings of middle east respiratory syndrome coronavirus (mers-cov)-related viruses in bats, and the ability of tylonycteris-batcov hku4 spike protein to utilize mers-cov receptor, human dipeptidyl peptidase 4 hdpp4, suggest a bat ancestral origin of mers-cov. we developed 12 primary bat cell lines from seven bat species, including tylonycteris pachypus, pipistrellus abramus and rhinolophus sinicus (hosts of tylonycteris-batcov hku4, pipistrellus-batcov hku5, and sars-related-cov respec ... | 2018 | 30531999 |