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discovery of a novel coronavirus, china rattus coronavirus hku24, from norway rats supports the murine origin of betacoronavirus 1 and has implications for the ancestor of betacoronavirus lineage a.we discovered a novel betacoronavirus lineage a coronavirus, china rattus coronavirus (chrcov) hku24, from norway rats in china. chrcov hku24 occupied a deep branch at the root of members of betacoronavirus 1, being distinct from murine coronavirus and human coronavirus hku1. its unique putative cleavage sites between nonstructural proteins 1 and 2 and in the spike (s) protein and low sequence identities to other lineage a betacoronaviruses (╬▓covs) in conserved replicase domains support chrcov h ...201525552712
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