| diversity of dromedary camel coronavirus hku23 in african camels revealed multiple recombination events among closely related betacoronaviruses of the subgenus embecovirus. | genetic recombination has frequently been observed in coronaviruses. here, we sequenced multiple complete genomes of dromedary camel coronavirus hku23 (dccov-hku23) from nigeria, morocco, and ethiopia and identified several genomic positions indicative of cross-species virus recombination events among other betacoronaviruses of the subgenus embecovirus (clade a beta-covs). recombinant fragments of a rabbit coronavirus (rbcov-hku14) were identified at the hemagglutinin esterase gene position. hom ... | 2019 | 31534035 |
| novel betacoronavirus in dromedaries of the middle east, 2013. | in 2013, a novel betacoronavirus was identified in fecal samples from dromedaries in dubai, united arab emirates. antibodies against the recombinant nucleocapsid protein of the virus, which we named dromedary camel coronavirus (dccov) uae-hku23, were detected in 52% of 59 dromedary serum samples tested. in an analysis of 3 complete dccov uae-hku23 genomes, we identified the virus as a betacoronavirus in lineage a1. the dccov uae-hku23 genome has g+c contents; a general preference for g/c in the ... | 2014 | 24655427 |
| metagenomic analysis of viromes of dromedary camel fecal samples reveals large number and high diversity of circoviruses and picobirnaviruses. | the recent discovery of middle east respiratory coronavirus and another novel dromedary camel coronavirus uae-hku23 in dromedaries has boosted interest in search of novel viruses in dromedaries. in this study, fecal samples of 203 dromedaries in dubai were pooled and deep sequenced. among the 7330 assembled viral contigs, 1970 were assigned to mammalian viruses. the largest groups of these contigs matched to picobirnaviridae, circoviridae, picornaviridae, parvoviridae, astroviridae and hepevirid ... | 2014 | 25461537 |
| isolation and characterization of dromedary camel coronavirus uae-hku23 from dromedaries of the middle east: minimal serological cross-reactivity between mers coronavirus and dromedary camel coronavirus uae-hku23. | recently, we reported the discovery of a dromedary camel coronavirus uae-hku23 (dccov uae-hku23) from dromedaries in the middle east. in this study, dccov uae-hku23 was successfully isolated in two of the 14 dromedary fecal samples using hrt-18g cells, with cytopathic effects observed five days after inoculation. northern blot analysis revealed at least seven distinct rna species, corresponding to predicted subgenomic mrnas and confirming the core sequence of transcription regulatory sequence mo ... | 2016 | 27164099 |