| vaccination with the chat strain of type 1 attenuated poliomyelitis virus in leopoldville. belgian congo. 2. studies of the safety and efficacy of vaccination. | in the course of the attenuated live poliovirus vaccination trial described in the preceding paper, an estimated 46 000 african children were given chat strain. among the 3400 children followed up by home visits, none developed paralytic poliomyelitis or aspetic meningitis. when bled 2-3 months after vaccination, 60% of previously type-1 negative children had antibodies; interference by wild enteric viruses is suggested in explanation of this low figure.two months after the beginning of vaccinat ... | 1960 | 14433516 |
| vaccination with the chat strain of type 1 attenuated poliomyelities virus in leopoldville, belgian congo. 1. description of the city, its history of poliomyelitis, and the plan of the vaccination campaign. | a trial of the chat, type 1, attenuated poliovirus strain of koprowski was begun in august 1958 in léopoldville, a city of 350 000 people, and possessing modern medical facilities, including an institute of public health.paralytic poliomyelitis is endemic in the city; since 1951 there has been an average annual incidence of 63 cases, and a rate of 19.4 cases per 100 000 inhabitants. more than 80% of the cases have occurred in african children less than 3 years old. consequently, a plan to vaccin ... | 1960 | 14415050 |