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the degree of leukocytosis and urine gata-3 mrna levels are risk factors for severe acute kidney injury in puumala virus nephropathia epidemica.puumala hantavirus (puuv) infection, also known as nephropathia epidemica, is the most common cause of hemorrhagic fever with renal syndrome (hfrs) in europe. the pathogenesis of puuv nephropathia epidemica is complex and multifactorial, and the risk factors for severe acute kidney injury (aki) during acute puuv infection are not well defined. we conducted a prospective study of hospitalized patients with puuv infection in tampere, finland to identify acute illness risk factors for hfrs severity ...201222523590
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