| a novel recombinant lineage's contribution to the outbreak of coxsackievirus a6-associated hand, foot and mouth disease in shanghai, china, 2012-2013. | since late 2012, coxsackievirus a6 (cva6) has gradually become the predominant pathogen responsible for hand-foot-mouth disease (hfmd) in several provinces of china. a total of 626 patients diagnosed with hfmd in shanghai, china from january 2012 to september 2013 were enrolled in this study. of these, 292 cva6 infected cases were subjected to clinical analyses. whole-genome sequencing, recombination and phylogenetic analyses were also performed. a recombinant cva6 monophyletic lineage was found ... | 2015 | 26121916 |
| serological detection and analysis of anti-vp1 responses against various enteroviruses (ev) (ev-a, ev-b and ev-c) in chinese individuals. | the overall serological prevalence of ev infections based on elisa remains unknown. in the present study, the antibody responses against vp1 of the ev-a species (enterovirus 71 (ev71), coxsackievirus a16 (ca16), coxsackievirus a5 (ca5) and coxsackievirus a6 (ca6)), of the ev-b species (coxsackievirus b3 (cb3)), and of the ev-c species (poliovirus 1 (pv1)) were detected and analyzed by a neibm (novel evolved immunoglobulin-binding molecule)-based elisa in shanghai blood donors. the serological pr ... | 2016 | 26917423 |