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eight genotypes (a-h) of hepatitis b virus infecting patients from san francisco and their demographic, clinical, and virological characteristics.clinical lines of evidence have been accumulated that hepatitis b virus (hbv) genotypes have characteristic geographical distributions and distinct clinical impact on liver diseases. the distribution of hbv genotypes was determined with reference to hepatitis b e antigen (hbeag) and alanine aminotransferase (alt) levels in 165 patients with hepatitis b in san francisco. hbv genotypes were determined by enzyme-linked immunosorbent assay (elisa) and the unclassified samples were sequenced within t ...200415221894
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