| emergence of porcine epidemic diarrhea virus in the united states: clinical signs, lesions, and viral genomic sequences. | during the 10 days commencing april 29, 2013, the iowa state university veterinary diagnostic laboratory received the first 4 of many submissions from swine farms experiencing explosive epidemics of diarrhea and vomiting affecting all ages, with 90-95% mortality in suckling pigs. histology revealed severe atrophy of villi in all segments of the small intestines with occasional villus-epithelial syncytial cells, but testing for rotaviruses and transmissible gastroenteritis virus (alphacoronavirus ... | 2013 | 23963154 |
| isolation and characterization of porcine epidemic diarrhea viruses associated with the 2013 disease outbreak among swine in the united states. | porcine epidemic diarrhea virus (pedv) was detected in may 2013 for the first time in u.s. swine and has since caused significant economic loss. obtaining a u.s. pedv isolate that can grow efficiently in cell culture is critical for investigating pathogenesis and developing diagnostic assays and for vaccine development. an additional objective was to determine which gene(s) of pedv is most suitable for studying the genetic relatedness of the virus. here we describe two pedv isolates (isu13-19338 ... | 2014 | 24197882 |
| origin, evolution, and genotyping of emergent porcine epidemic diarrhea virus strains in the united states. | coronaviruses are known to infect humans and other animals and cause respiratory and gastrointestinal diseases. here we report the emergence of porcine epidemic diarrhea virus (pedv) in the united states and determination of its origin, evolution, and genotypes based on temporal and geographical evidence. histological lesions in small intestine sections of affected pigs and the complete genomic sequences of three emergent strains of pedv isolated from outbreaks in minnesota and iowa were charact ... | 2013 | 24129257 |