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alternate circulation of recent equine-2 influenza viruses (h3n8) from two distinct lineages in the united states.phylogenetic and antigenic analyses indicate that recent circulating equine-2 influenza viruses in the united states have been alternating between two genetic and antigenic distinct lineages since 1996. the evolution rates for these two lineages, the kentucky and the florida lineage, are very similar. for the earlier isolates in the kentucky lineage, there are multiple and sequential nonsynonymous substitutions at antigenic sites b and d. however, there are no changes at any of these antigenic s ...200415019234
diverged evolution of recent equine-2 influenza (h3n8) viruses in the western hemisphere.we reported previously that equine-2 influenza a virus (h3n8) had evolved into two genetically and antigenically distinct "eurasian" and "american" lineages. phylogenetic analysis, using the ha1 gene of more recent american isolates, indicated a further divergence of these viruses into three evolution lineages: a south american lineage, a kentucky lineage, and a florida lineage. these multiple evolution pathways were not due to geographic barriers, as viruses from different lineages co-circulate ...200111504416
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