| [two new cases of sporadic creutzfeldt-jakob disease in madrid, spain]. | creutzfeldt-jakob disease is a transmissible spongiform encephalopathy, in which there is typically an accumulation of an altered isoform of the prion protein in the brain. the sporadic form is characterised by presenting a rapidly progressive dementia, with signs and symptoms of pyramidal, extrapyramidal, cerebellar and cortical involvement, as well as the presence of myoclonias. diagnosis is based on the clinical findings in combination with the typical results of an electroencephalogram, cere ... | 2011 | 21796606 |