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review. the origin of the prion agent of kuru: molecular and biological strain typing.kuru is an acquired human prion disease that primarily affected the fore linguistic group of the eastern highlands of papua new guinea. the central clinical feature of kuru is progressive cerebellar ataxia and, in sharp contrast to most cases of sporadic creutzfeldt-jakob disease (cjd), dementia is a less prominent and usually late clinical feature. in this regard, kuru is more similar to variant cjd, which also has similar prodromal symptoms of sensory disturbance and joint pains in the legs an ...200818849291
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