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genomic characterization of echovirus 6 causing aseptic meningitis in hokkaido, japan: a novel cluster in the nonstructural protein coding region of human enterovirus b.we determined four complete nucleotide sequences of echovirus 6 (e6) isolated from an epidemic of aseptic meningitis (am) in hokkaido, japan, in 2011. phylogenetic analysis of the genes encoding viral capsid protein 1 revealed that the strains were closely related to e6 strains isolated in china in recent years, but they were distantly related to e6 strains isolated from patients with am in osaka prefecture, japan, in 2011. the genes encoding the viral protease and rna-dependent rna polymerase ( ...201323178967
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