Publications
Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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increased incidence of sporadic creutzfeldt-jakob disease on the island of crete associated with a high rate of prnp 129-methionine homozygosity in the local population. | since the spring of 1997, when the neurology department of the university hospital of crete admitted its first patient, nine cases (eight neuropathologically confirmed and one probable) of sporadic creutzfeldt-jakob disease (scjd) have been recorded. this represents an annual incidence five-fold higher than expected based on the island's population (0.54 million). molecular analysis of the prion-protein gene (prnp) showed no mutations in any of the seven cjd cases studied. five patients (ages 64 ... | 2001 | 11506406 |