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population genetics of chrysomela tremulae: a first step towards management of transgenic bacillus thuringiensis poplars populus tremula x .p. tremuloides.many strategies have been proposed for delaying the development of insect resistance to bacillus thuringiensis (bt). the current paradigm for bt resistance management is the high dose-refuge strategy. for this strategy to be successful: (i) heterozygotes must be killed in treated areas, (ii) resistant alleles must be rare (frequency < 10-3), and (iii) there must be a high level of gene flow between populations to ensure random mating. we studied gene flow within and between populations with a vi ...200011338433
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