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dengue hemorrhagic fever caused by sequential dengue 1-3 virus infections over a long time interval: havana epidemic, 2001-2002.a dengue epidemic caused by dengue virus 3 (denv-3) occurred in cuba in 2001-2002. it included cases of dengue hemorrhagic fever/dengue shock syndrome (dhf/dss). we report neutralizing antibody studies on sera from 54 of 78 dhf/dss patients that provide evidence of infections occurring in the sequence denv-1 followed by denv-3. no sera showed infection in the sequence denv-2 followed by denv-3. some sera showed a pattern of infection in the sequence denv-1 followed by denv-2 and then denv-3. how ...200617172378
dual infection with dengue virus 3 and human immunodeficiency virus 1 in havana, cuba.although dengue virus (den) endemic regions overlap with human immunodeficiency virus 1 (hiv) high incidence areas, little has been documented on hiv and den mixed infection. here we report den/hiv concurrent infections recorded during the den-3 epidemic in 2001-2002 in havana. serologic-confirmed den is described in two hiv-infected subjects with dengue fever symptoms. although patients had dengue disease, the cd4+ cells remained within normal levels and no accelerated progression of hiv diseas ...200919759497
[biological properties of virus dengue-3 strains isolated during the epidemic ocurred in havana, 2001-2002].during dengue epidemics in cuba, an increase in clinical severity with the epidemics progression in time, particularly in secondary infections, have been frequently observed. it is considered that this increase could be related with genetic changes in the circulating virus.201223444637
increasing clinical severity during a dengue virus type 3 cuban epidemic: deep sequencing of evolving viral populations.during the dengue virus type 3 (denv-3) epidemic that occurred in havana in 2001 to 2002, severe disease was associated with the infection sequence denv-1 followed by denv-3 (denv-1/denv-3), while the sequence denv-2/denv-3 was associated with mild/asymptomatic infections. to determine the role of the virus in the increasing severity demonstrated during the epidemic, serum samples collected at different time points were studied. a total of 22 full-length sequences were obtained using a deep-sequ ...201626889031
epidemiological studies on dengue virus type 3 in playa municipality, havana, cuba, 2001-2002.recognizing the uniqueness of secondary dengue virus (denv)-1/3 dengue hemorrhagic fever/dengue shock syndrome (dhf/dss) cases at an interval of 24 years, we sought to estimate denv infections as well as the ratios between mild disease and dhf/dss by denv infection sequence in playa district (havana, cuba) during the 2001-2002 outbreak of dengue virus type 3 (denv-3).201222277259
classical dengue hemorrhagic fever resulting from two dengue infections spaced 20 years or more apart: havana, dengue 3 epidemic, 2001-2002.to report the clinical, laboratory and sonographic findings in 76 adult cases of dengue hemorrhagic fever (dhf).200516023878
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