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severe fever with thrombocytopenia syndrome, shandong province, china, 2011.severe fever with thrombocytopenia syndrome (sfts) is an emerging infectious disease in china. the incidence and clinical and laboratory characteristics of sfts are not clearly defined. during may 22-october 2, 2011, a total of 24 patients with fever, thrombocytopenia, and leukopenia were clinically diagnosed as having sfts in yiyuan county, shandong province, china. we conducted laboratory tests for these sfts patients. sfts virus (sftsv) infection was confirmed in 22 patients by using reverse ...201424378074
novel sub-lineages, recombinants and reassortants of severe fever with thrombocytopenia syndrome virus.severe fever with thrombocytopenia syndrome virus (sftsv) has been continuously circulating in eastern asia in recent years, without the availability of effective vaccines or antiviral drugs, posing a serious threat to public health, particularly in the central-eastern provinces of china. in this study, we isolated and sequenced four new sftsv strains from shandong province identified in 2015. phylogenetic analysis, with all publicly available l, m and s gene segments, revealed that the four new ...201728117273
seroprevalence of severe fever with thrombocytopenia syndrome virus in hedgehog from china.severe fever with thrombocytopenia syndrome, an emerging hemorrhagic fever, is caused by severe fever with thrombocytopenia syndrome virus (sftsv), a tick-borne bunyavirus. information regarding sftsv animal hosts is very limited. in this study, we showed that 64% (9/14) of hedgehogs in shandong province, china were seropositive to sftsv antibody, suggesting that hedgehog could be a vertebrate parasitifer for sftsv.201728323557
a cluster of symptomatic and asymptomatic infections of severe fever with thrombocytopenia syndrome caused by person-to-person transmission.severe fever with thrombocytopenia syndrome virus (sftsv) is a novel phlebovirus that was identified to be the etiological pathogen of the emerging infectious disease, severe fever with thrombocytopenia syndrome (sfts). sftsv could be transmitted through tick bite. transmission of sftsv among humans has also been reported mainly through direct blood contact. in july 2014, a cluster of six suspected sfts cases occurred in shandong province, china. in this cluster, both symptomatic and asymptomati ...201728722592
a cross-sectional survey of severe fever with thrombocytopenia syndrome virus infection of domestic animals in laizhou city, shandong province, china.a serosurvey of severe fever with thrombocytopenia syndrome virus (sftsv) infection in domestic animals was conducted in the rural areas of laizhou city, shandong province, china to determine strategies for control and prevention of sfts. serum samples were collected from cattle, goats, dogs, pigs, and chickens and antibodies against sftsv were detected by double-antigen sandwich enzyme-linked immunosorbent assay (elisa). of 641 serum samples, the sftsv seropositive rate was 41.8% (268/641): 74. ...201424451093
[prevalence and homology analysis on human and animals severe fever with thrombocytopenia syndrome virus infection in yantai of shandong province].to learn the prevalence of infection of human and animals severe fever with thrombocytopenia syndrome bunyavirus (sftsv) in yantai, shandong province, and to analyze the pathogenic features of sftsv as well as its relationship between human and animal hosts.201425059360
severe fever with thrombocytopenia syndrome virus, shandong province, china.severe fever with thrombocytopenia syndrome, which results in severe illness and has a high case-fatality rate, is caused by a novel bunyavirus, severe fever with thrombocytopenia syndrome virus. we found that samples from 2/237 (0.8%) healthy persons and 111/134 (83%) goats in yiyuan county, shandong province, china, were seropositive for this virus.022608264
haemaphysalis longicornis ticks as reservoir and vector of severe fever with thrombocytopenia syndrome virus in china.severe fever with thrombocytopenia syndrome (sfts) is an emerging hemorrhagic fever in east asia caused by sfts virus (sftsv), a newly discovered phlebovirus. the haemaphysalis longicornis tick has been suspected to be the vector of sftsv. to determine whether sftsv can be transmitted among ticks, from ticks to animals, and from animals to ticks, we conducted transmission studies between developmental stages of h. longicornis ticks and between ticks and mice. using reverse transcription pcr, we ...026402039
sfts virus in ticks in an endemic area of china.in total, 3,145 ticks of the species haemaphysalis longicornis (3,048; 96.9%), r. microplus (82; 2.6%), h. campanulata (9; 0.3%), and dermacentor sinicus (5; 0.2%) were collected from animals and vegetation at yantai in shandong province. both adult and immature ticks were obtained, and all ticks collected from vegetation were unfed. eggs were obtained from 22 blood-fed female ticks through maintenance at room temperature after collection. severe fever with thrombocytopenia syndrome virus (sftsv ...201525711611
severe fever with thrombocytopenia syndrome virus among domesticated animals, china.to investigate the infections of severe fever with thrombocytopenia syndrome virus (sftsv) in domesticated animals, we sampled a total of 3,039 animals in 2 counties in shandong province, people's republic of china, from april to november 2011. sftsv-specific antibodies were detected in 328 (69.5%) of 472 sheep, 509 (60.5%) of 842 cattle, 136 (37.9%) of 359 dogs, 26 (3.1%) of 839 pigs, and 250 (47.4%) of 527 chickens. sftsv rna was detected in all sampled animal species, but the prevalence was l ...201323648209
first detection of severe fever with thrombocytopenia syndrome virus in the tick species haemaphysalis concinna in shandong province, china.the aim of this study was to detect severe fever with thrombocytopenia syndrome virus (sftsv) infection using polymerase chain reaction (pcr) amplification in adult haemaphysalis concinna ticks. a total of 72 adult h. concinna ticks were obtained from 35 goats, three adult h. concinna ticks (4.17 %) collected from two goats were found to be infected with sftsv via pcr assay. sequence analysis showed that the partial segment m glycoprotein gene of sftsv was about 500 bases long by polymerase chai ...201526350381
detection of a novel rickettsia from leptotrombidium scutellare mites (acari: trombiculidae) from shandong of china.leptotrombidium scutellare mites, the vector of orientia tsutsugamushi, have rarely been reported to associate with rickettsia species. three hundred nineteen chiggers were collected from the ears of 32 rodents captured in huangdao district of qingdao city, china, in october 2015. the chigger samples were tested for rickettsia, severe fever with thrombocytopenia syndrome virus, and hantavirus by pcr or rt-pcr amplification. all mites were classified morphologically and molecularly as l. scutella ...201728399204
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