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phylogenetic analysis of three orf virus strains isolated from different districts in shandong province, east china.orf virus (orfv) is the causative agent of contagious ecthyma, which is a zoonotic disease that affects sheep, goats, wild small ruminants and humans. shandong province in east china is one of the main producing areas in china for sheep and goats. here, we conducted epidemiological surveys in different areas in this province, isolated three orf virus strains, sdlc, sdta and sdjn, from goat flocks and then analyzed the genetic evolution of these strains. the orfv011, orfv059, orfv109, orfv110 and ...201626311786
phylogenetic analysis of two chinese orf virus isolates based on sequences of b2l and vir genes.orf virus (orfv) is an enveloped virus with a double-stranded dna genome, causing a contagious pustular dermatitis, mainly in goats and sheep. in this study, two strains of orfv were isolated from sheep and goat samples in xinjiang and shaanxi, china. the b2l and virus interferon resistance (vir) genes of these two isolates were sequenced and analyzed after pcr amplification. phylogenetic analysis showed that the two isolates clustered with other orfv strains but were separated into different su ...201323443934
characterization of an orf virus isolate from an outbreak in heilongjiang province, china.contagious ecthyma, caused by orf virus (orfv), is an epitheliotrophic contagious disease with zoonotic implications that mainly affects sheep, goats, wild ruminants, and humans. recently, a novel orfv strain, ov/hlj/04, was successfully isolated from the skin and mucosal lesions of a goat with severe clinical sore mouth symptoms in heilongjiang province of china. the ov/hlj/04 isolate was characterized by electron microscopy, serological tests, and experimental reproduction of disease. the puri ...201728631053
human infection with orf virus from goats in china, 2012.orf virus, which belongs to the parapoxvirus genus, induces a zoonotic infectious disease characterized by acute, highly vascularized cutaneous pustular lesions in sheep and goats. a number of orf outbreaks have been reported in sheep and goats in recent years, but no reports have described an orf virus strain from humans in china. in this study, we diagnosed orf virus infection in two people, a mother and son, in the gansu province of china. the human orf virus was isolated and its phylogenetic ...201424745915
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