| characterization of a novel h3n2 influenza virus isolated from domestic ducks in china. | cases of human infection with a novel h7n9 avian influenza virus (aiv) were first reported in march 2013, which caused 115 deaths within a single year. beyond that, other subtypes of h7 aiv were isolated from poultry in eastern china during the same period, including h7n7 and h7n2 aiv. in the present study, a subtype h3n2 aiv was isolated from ducks from anhui province, china. sequence and phylogenetic analyses revealed that seven gene segments of this virus showed the highest sequence homology ... | 2016 | 27000112 |
| analysis of recombinant h7n9 wild-type and mutant viruses in pigs shows that the q226l mutation in ha is important for transmission. | the fact that there have been more than 300 human infections with a novel avian h7n9 virus in china indicates that this emerging strain has pandemic potential. furthermore, many of the h7n9 viruses circulating in animal reservoirs contain putative mammalian signatures in the ha and pb2 genes that are believed to be important in the adaptation of other avian strains to humans. to date, the definitive roles of these mammalian-signature substitutions in transmission and pathogenesis of h7n9 viruses ... | 2014 | 24807722 |