co-circulation of canine coronavirus i and iia/b with high prevalence and genetic diversity in heilongjiang province, northeast trace the evolution of canine coronavirus (ccov), 201 stool samples from diarrheic dogs in northeast china were subjected to reverse transcription-polymerase chain reactions (rt-pcrs) targeting the partial m and s genes of ccov, followed by an epidemiological analysis. m gene rt-pcrs showed that 28.36% (57/201) of the samples were positive for ccov; of the 57 positive samples, ccov-i and ccov-ii accounted for 15.79% (9/57) and 84.21% (48/57), respectively. a sequence comparison of the partial ...201626771312
co-circulation of the rare cpv-2c with unique gln370arg substitution, new cpv-2b with unique thr440ala substitution, and new cpv-2a with high prevalence and variation in heilongjiang province, northeast trace evolution of canine parvovirus-2 (cpv-2), a total of 201 stool samples were collected from dogs with diarrhea in heilongjiang province of northeast china from may 2014 to april 2015. the presence of cpv-2 in the samples was determined by pcr amplification of the vp2 gene (568 bp) of cpv-2. the results revealed that 95 samples (47.26%) were positive for cpv-2, and they showed 98.8%-100% nucleotide identity and 97.6%-100% amino acid identity. of 95 cpv-2-positive samples, types new2a (ser ...201526348721
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