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molecular characterization of msp2/p44 of anaplasma phagocytophilum isolated from infected patients and haemaphysalis longicornis in laizhou bay, shandong province, china.molecular characterization of the msp2/p44 protein of anaplasma phagocytophilum may determine not only if the bacterium is capable of invading hosts but also whether it generates antigenic variation for the purpose of escaping the host immune response, resulting in various pathologic injuries and serious clinical outcomes. chinese anaplasmosis patients usually present with serious manifestations, and the fatality rate is as high as 26.5%. in this study, we amplified, cloned and sequenced the msp ...201324167608
molecular analysis of anaplasma phagocytophilum isolated from patients with febrile diseases of unknown etiology in china.although anaplasmosis cases have been nationally identified in china, no human isolates of a. phagocytophilum have been obtained, which limits the analysis of any molecular and genetic contributions to patients' severe clinical manifestations and the study of the bacteria's pathogeneses in china. given this situation, a joint project was conducted in 2009-2010. a total of 421 febrile cases of unknown etiology were collected and the patients' blood samples were collected for laboratory diagnoses ...201323451170
rural residents in china are at increased risk of exposure to tick-borne pathogens anaplasma phagocytophilum and ehrlichia chaffeensis.as emerging tick born rickettsial diseases caused by a. phagocytophilum and e. chaffeensis, anaplasmosis and ehrlichiosis have become a serious threat to human and animal health throughout the world. in particular, in china, an unusual transmission of nosocomial cases of human granulocytic anaplasmosis occurred in anhui province in 2006 and more recent coinfection case of a. phagocytophilum and e. chaffeensis was documented in shandong province. although the seroprevalence of human granulocytic ...201424877080
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