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monoclonal antibody characterization of jamestown canyon (california serogroup) virus topotypes isolated in canada.jamestown canyon (jc) virus of the california (cal) serogroup has been isolated in 12 american states and 6 canadian provinces. a study was undertaken to produce monoclonal antibodies (mabs) to jc virus and to use these mabs to assay for possible heterogeneity among naturally occurring jc topotypes in canada. mabs were produced to the prototype strain of jc virus using balb/c mice. twenty-seven secreting mabs were obtained and three of these mabs were propagated and studied. all three mabs, m1 ( ...19921418321
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