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complex integrons containing qnrb4-ampc (bla(dha-1)) in plasmids of multidrug-resistant citrobacter freundii from wastewater.microbial populations in wastewater treatment plants (wwtps) are increasingly being recognized as environmental reservoirs of antibiotic resistance genes. pcr amplicons for plasmid-mediated quinolone resistance determinants qnra, qnrb, and qnrs were recorded in samples from a wwtp in vancouver, british columbia. six strains of ciprofloxacin-resistant citrobacter freundii were isolated and found to carry mutations in gyra and parc, as well as multiple plasmid-borne resistance genes, collectively ...201223461518
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