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detection and characterization of oxa-48-producing klebsiella pneumoniae originated in bulgaria.we report the identification of oxa-48-producing klebsiella pneumoniae, causing peritonitis in a cancer patient admitted to the oncology hospital in sofia. the isolate had reduced susceptibility to carbapenems but remained susceptible to extended-spectrum cephalosporins. pcr and sequencing confirmed the presence of blaoxa-48 gene flanked by two intact copies of is1999 on truncated δtn1999.1. this transposon was located on unusual non-typeable 29-kb plasmid that could be transferred only by trans ...201626017897
extended-spectrum beta-lactamase (esbl) ctx-m-15-producing escherichia coli and klebsiella pneumoniae in sofia, bulgaria.during a survey of extended-spectrum beta-lactamase (esbl)-producing enterobacteriaceae in bulgaria in 2001-2002, three isolates from sofia (two escherichia coli, one klebsiella pneumoniae) showed cefotaxime mics that were decreased in the presence of clavulanate and were 2-8-fold higher than those of ceftazidime. resistance was transferred to a sensitive recipient strain of e. coli. both wild-type and transconjugant strains produced a cefotaxime-hydrolysing beta-lactamase of pi 8.8. sequencing ...200415301679
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