| tropical leg ulcers in children: more than yaws. | the management of yaws has changed in recent years. mass treatment with oral azithromycin has replaced intramuscular benzathine benzylpenicillin. treponemal and non-treponemal serology (equivalent to tpha and rpr) point-of-care blood testing is now available. in addition, recent studies in yaws endemic regions have shown that a significant number of leg ulcers in children which are clinically suggestive of yaws are caused by haemophilus ducreyi. it is noteworthy that the world health organizatio ... | 2016 | 26289420 |
| cutaneous chancroid in a visitor from vanuatu. | a 23-year-old woman from vanuatu presented to an australian hospital with a 3-week history of a non-healing ulcer on the lower leg. a swab was submitted for a multiplex polymerase chain reaction designed to investigate genital ulcerative conditions. haemophilus ducreyi was detected and the gene product was subsequently sequenced, confirming the diagnosis of cutaneous chancroid. the lesion responded to intramuscular benzathine penicillin. this report adds further evidence that cutaneous chancroid ... | 2008 | 18412810 |
| haemophilus ducreyi cutaneous ulcer strains diverged from both class i and class ii genital ulcer strains: implications for epidemiological studies. | haemophilus ducreyi has emerged as a major cause of cutaneous ulcers (cu) in yaws-endemic regions of the tropics in the south pacific, south east asia and africa. h. ducreyi was once thought only to cause the genital ulcer (gu) disease chancroid; gu strains belong to 2 distinct classes, class i and class ii. using whole-genome sequencing of 4 cu strains from samoa, 1 from vanuatu and 1 from papua new guinea, we showed that cu strains diverged from the class i strain 35000hp and that one cu strai ... | 2016 | 28027326 |